Homo sapiens

0 known processes

IFI44

interferon-induced protein 44

(Aliases: p44,MTAP44)

IFI44 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
defense response to virus GO:0051607 71 1.000
viral life cycle GO:0019058 132 1.000
response to other organism GO:0051707 261 0.999
response to biotic stimulus GO:0009607 276 0.998
viral process GO:0016032 146 0.998
multi organism cellular process GO:0044764 156 0.997
regulation of multi organism process GO:0043900 157 0.997
negative regulation of viral genome replication GO:0045071 35 0.995
defense response to other organism GO:0098542 129 0.995
response to virus GO:0009615 126 0.995
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.993
negative regulation of viral process GO:0048525 66 0.993
regulation of defense response to virus GO:0050688 33 0.988
response to external biotic stimulus GO:0043207 261 0.987
regulation of viral genome replication GO:0045069 48 0.985
interspecies interaction between organisms GO:0044419 156 0.985
regulation of viral process GO:0050792 103 0.982
immune effector process GO:0002252 159 0.976
negative regulation of multi organism process GO:0043901 92 0.971
positive regulation of rig i signaling pathway GO:1900246 4 0.970
viral genome replication GO:0019079 50 0.957
innate immune response GO:0045087 178 0.956
defense response GO:0006952 315 0.955
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.947
immune response GO:0006955 307 0.945
response to cytokine GO:0034097 232 0.937
response to interferon alpha GO:0035455 11 0.874
organophosphate biosynthetic process GO:0090407 163 0.801
regulation of defense response GO:0031347 154 0.799
response to dsrna GO:0043331 25 0.793
t helper 2 cell cytokine production GO:0035745 3 0.665
regulation of cytokine production GO:0001817 232 0.663
rig i signaling pathway GO:0039529 7 0.640
positive regulation of defense response GO:0031349 87 0.600
cytokine production GO:0001816 247 0.586
nucleoside phosphate biosynthetic process GO:1901293 109 0.563
positive regulation of cytokine production GO:0001819 167 0.557
pattern recognition receptor signaling pathway GO:0002221 48 0.535
regulation of rig i signaling pathway GO:0039535 6 0.533
immune response activating signal transduction GO:0002757 90 0.530
negative regulation of protein maturation GO:1903318 142 0.493
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.492
cellular response to interferon alpha GO:0035457 4 0.483
regulation of immune effector process GO:0002697 91 0.474
regulation of response to biotic stimulus GO:0002831 55 0.464
transport of virus GO:0046794 14 0.452
regulation of defense response to virus by host GO:0050691 22 0.411
regulation of intracellular transport GO:0032386 195 0.397
regulation of apoptotic signaling pathway GO:2001233 175 0.357
nuclear transport GO:0051169 179 0.353
positive regulation of cell death GO:0010942 263 0.352
regulation of protein transport GO:0051223 213 0.345
positive regulation of multi organism process GO:0043902 56 0.342
regulation of response to external stimulus GO:0032101 222 0.330
organonitrogen compound biosynthetic process GO:1901566 200 0.328
mda 5 signaling pathway GO:0039530 4 0.318
glycosylation GO:0070085 71 0.315
activation of immune response GO:0002253 114 0.304
negative regulation of defense response to virus by host GO:0050689 4 0.290
negative regulation of catalytic activity GO:0043086 335 0.275
positive regulation of viral entry into host cell GO:0046598 3 0.269
positive regulation of innate immune response GO:0045089 79 0.267
chemical homeostasis GO:0048878 306 0.257
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.256
viral transcription GO:0019083 35 0.254
positive regulation of interferon beta production GO:0032728 17 0.253
cellular response to cytokine stimulus GO:0071345 181 0.241
positive regulation of immune effector process GO:0002699 40 0.235
regulation of binding GO:0051098 111 0.221
regulation of fas signaling pathway GO:1902044 2 0.220
regulation of innate immune response GO:0045088 97 0.220
innate immune response activating signal transduction GO:0002758 48 0.191
activation of innate immune response GO:0002218 55 0.190
multi organism intracellular transport GO:1902583 14 0.183
response to nitrogen compound GO:1901698 184 0.182
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.178
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.169
intracellular receptor signaling pathway GO:0030522 104 0.165
regulation of nuclease activity GO:0032069 11 0.163
regulation of mda 5 signaling pathway GO:0039533 4 0.161
protein oligomerization GO:0051259 173 0.160
protein maturation GO:0051604 233 0.156
positive regulation of immune response GO:0050778 159 0.153
cellular response to dsrna GO:0071359 19 0.153
cytoplasmic transport GO:0016482 379 0.153
regulation of intracellular transport of viral material GO:1901252 2 0.150
positive regulation of immune system process GO:0002684 283 0.149
intracellular transport of virus GO:0075733 14 0.149
regulation of ribonuclease activity GO:0060700 3 0.148
response to exogenous dsrna GO:0043330 10 0.147
purine nucleotide biosynthetic process GO:0006164 84 0.143
positive regulation of programmed cell death GO:0043068 249 0.122
multi organism transport GO:0044766 14 0.118
protein myristoylation GO:0018377 1 0.115
intracellular protein transport GO:0006886 270 0.113
regulation of establishment of protein localization GO:0070201 242 0.109
negative regulation of protein metabolic process GO:0051248 391 0.108
negative regulation of immune system process GO:0002683 136 0.108
multi organism localization GO:1902579 14 0.107
regulation of cytoplasmic transport GO:1903649 149 0.105
apoptotic signaling pathway GO:0097190 268 0.103
negative regulation of peptidase activity GO:0010466 91 0.102
lipoprotein metabolic process GO:0042157 42 0.101
response to lipid GO:0033993 206 0.100
regulation of immune response GO:0050776 201 0.098
positive regulation of interferon alpha production GO:0032727 11 0.097
multi organism metabolic process GO:0044033 41 0.096
ncrna metabolic process GO:0034660 108 0.093
regulation of protein processing GO:0070613 150 0.092
regulation of protein localization GO:0032880 296 0.091
carbohydrate derivative biosynthetic process GO:1901137 207 0.091
regulation of cell migration GO:0030334 289 0.088
negative regulation of hydrolase activity GO:0051346 182 0.087
rna interference GO:0016246 4 0.085
positive regulation of transport GO:0051050 336 0.081
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.080
intracellular transport of viral protein in host cell GO:0019060 4 0.076
positive regulation of type i interferon production GO:0032481 20 0.074
lipoprotein biosynthetic process GO:0042158 33 0.073
cellular response to nitrogen compound GO:1901699 144 0.073
negative regulation of transport GO:0051051 176 0.072
negative regulation of defense response to virus GO:0050687 10 0.070
secretion GO:0046903 254 0.069
glucose metabolic process GO:0006006 45 0.069
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.068
negative regulation of proteolysis GO:0045861 132 0.068
negative regulation of intracellular transport of viral material GO:1901253 2 0.068
nucleotide biosynthetic process GO:0009165 109 0.066
cellular response to organic cyclic compound GO:0071407 127 0.062
negative regulation of locomotion GO:0040013 118 0.062
regulation of nucleocytoplasmic transport GO:0046822 98 0.062
mhc class ii biosynthetic process GO:0045342 4 0.062
negative regulation of programmed cell death GO:0043069 321 0.061
fas signaling pathway GO:0036337 3 0.061
negative regulation of calcium ion import GO:0090281 1 0.060
positive regulation of intracellular protein transport GO:0090316 76 0.059
negative regulation of cell death GO:0060548 345 0.059
viral gene expression GO:0019080 35 0.057
negative regulation of cytokine production GO:0001818 82 0.056
positive regulation of proteolysis GO:0045862 142 0.056
negative regulation of response to external stimulus GO:0032102 83 0.054
purine containing compound biosynthetic process GO:0072522 88 0.054
posttranscriptional regulation of gene expression GO:0010608 213 0.053
regulation of gene expression epigenetic GO:0040029 73 0.053
response to organic cyclic compound GO:0014070 204 0.052
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.051
protein processing GO:0016485 226 0.051
regulation of secretion by cell GO:1903530 177 0.049
immune response regulating signaling pathway GO:0002764 97 0.049
positive regulation of hydrolase activity GO:0051345 331 0.048
protein modification by small protein conjugation GO:0032446 342 0.047
symbiont intracellular protein transport in host GO:0030581 4 0.047
monosaccharide metabolic process GO:0005996 74 0.046
cellular response to molecule of bacterial origin GO:0071219 62 0.046
regulation of locomotion GO:0040012 329 0.046
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 3 0.046
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
negative regulation of multicellular organismal process GO:0051241 317 0.045
positive regulation of viral process GO:0048524 37 0.044
negative regulation of apoptotic process GO:0043066 316 0.044
regulation of protein maturation GO:1903317 150 0.044
regulation of cell motility GO:2000145 299 0.042
regulation of dna binding GO:0051101 37 0.042
regulation of cellular component movement GO:0051270 334 0.041
regulation of peptidase activity GO:0052547 180 0.041
nucleocytoplasmic transport GO:0006913 176 0.040
extracellular transport GO:0006858 4 0.040
ncrna processing GO:0034470 83 0.040
regulation of t helper 2 cell cytokine production GO:2000551 2 0.039
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.038
cellular macromolecular complex assembly GO:0034622 324 0.038
regulation of secretion GO:0051046 194 0.037
regulation of cell cycle GO:0051726 393 0.037
immune system development GO:0002520 195 0.037
positive regulation of protein complex assembly GO:0031334 86 0.036
single organism nuclear import GO:1902593 104 0.036
regulation of protein secretion GO:0050708 86 0.036
cellular macromolecule catabolic process GO:0044265 380 0.035
negative regulation of intracellular transport GO:0032387 60 0.034
regulation of proteolysis GO:0030162 293 0.034
regulation of purine nucleotide metabolic process GO:1900542 264 0.034
regulation by virus of viral protein levels in host cell GO:0046719 4 0.032
nucleotide catabolic process GO:0009166 408 0.032
negative regulation of cell motility GO:2000146 104 0.032
negative regulation of response to biotic stimulus GO:0002832 18 0.031
protein deubiquitination GO:0016579 79 0.031
interleukin 2 secretion GO:0070970 3 0.031
extrinsic apoptotic signaling pathway GO:0097191 119 0.031
gene silencing by mirna GO:0035195 23 0.031
positive regulation of developmental process GO:0051094 314 0.030
negative regulation of protein processing GO:0010955 142 0.030
macromolecule glycosylation GO:0043413 63 0.030
positive regulation of cellular component organization GO:0051130 376 0.030
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.029
negative regulation of defense response GO:0031348 47 0.029
positive regulation of cellular component biogenesis GO:0044089 158 0.029
compound eye development GO:0048749 1 0.028
negative regulation of viral transcription GO:0032897 23 0.028
secretion by cell GO:0032940 226 0.028
positive regulation of cell differentiation GO:0045597 211 0.028
regulation of mitochondrial membrane potential GO:0051881 23 0.028
rna processing GO:0006396 255 0.027
response to oxygen containing compound GO:1901700 369 0.027
protein export from nucleus GO:0006611 29 0.026
posttranscriptional gene silencing GO:0016441 25 0.026
positive regulation of response to external stimulus GO:0032103 88 0.026
regulation of endopeptidase activity GO:0052548 170 0.025
organophosphate catabolic process GO:0046434 430 0.025
purine ribonucleotide catabolic process GO:0009154 404 0.024
glycoprotein metabolic process GO:0009100 110 0.024
positive regulation of phosphorylation GO:0042327 394 0.024
protein lipidation GO:0006497 33 0.024
transmembrane transport GO:0055085 399 0.024
protein secretion GO:0009306 98 0.024
cellular response to oxygen containing compound GO:1901701 276 0.023
negative regulation of immune response GO:0050777 40 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
response to bacterium GO:0009617 144 0.023
regulation of protein complex assembly GO:0043254 147 0.023
positive regulation of cytoplasmic transport GO:1903651 82 0.023
angiogenesis GO:0001525 147 0.023
regulation of transferase activity GO:0051338 355 0.023
negative regulation of endothelial cell migration GO:0010596 29 0.023
regulation of kinase activity GO:0043549 314 0.022
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.022
positive regulation of protein transport GO:0051222 135 0.022
response to molecule of bacterial origin GO:0002237 82 0.022
divalent inorganic cation transport GO:0072511 158 0.022
regulation of cytoskeleton organization GO:0051493 177 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
hemopoiesis GO:0030097 180 0.022
negative regulation of endopeptidase activity GO:0010951 84 0.022
regulation of ion transport GO:0043269 189 0.022
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.021
zymogen activation GO:0031638 70 0.021
negative regulation of cell cycle GO:0045786 193 0.021
negative regulation of cell migration GO:0030336 102 0.021
hematopoietic or lymphoid organ development GO:0048534 186 0.021
regulation of protein binding GO:0043393 66 0.021
response to type i interferon GO:0034340 14 0.021
rhythmic behavior GO:0007622 2 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.020
protein import into nucleus GO:0006606 104 0.020
female gamete generation GO:0007292 2 0.020
mapk cascade GO:0000165 288 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
regulation of protein export from nucleus GO:0046825 15 0.020
regulation of metal ion transport GO:0010959 120 0.020
neuron projection regeneration GO:0031102 1 0.020
positive regulation of mapk cascade GO:0043410 190 0.020
activation of cysteine type endopeptidase activity GO:0097202 57 0.020
cellular response to lipid GO:0071396 127 0.020
negative regulation of cellular component movement GO:0051271 106 0.019
regulation of actin filament based process GO:0032970 141 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
negative regulation of protein deubiquitination GO:0090086 3 0.019
positive regulation of organelle organization GO:0010638 195 0.019
protein glycosylation GO:0006486 62 0.019
positive regulation of erk1 and erk2 cascade via tnfsf11 mediated signaling GO:0071848 2 0.019
negative regulation of transferase activity GO:0051348 124 0.019
regulation of type i interferon production GO:0032479 26 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
regulation of viral transcription GO:0046782 34 0.019
cellular protein catabolic process GO:0044257 261 0.019
positive regulation of locomotion GO:0040017 186 0.019
protein sumoylation GO:0016925 25 0.018
calcium ion import GO:0070509 23 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
regulation of cysteine type endopeptidase activity GO:2000116 127 0.018
protein targeting GO:0006605 187 0.018
glucose homeostasis GO:0042593 31 0.018
protein acylation GO:0043543 138 0.018
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.018
signal transduction by p53 class mediator GO:0072331 72 0.018
negative regulation of immune effector process GO:0002698 38 0.018
myeloid cell differentiation GO:0030099 117 0.017
regulation of protein localization to nucleus GO:1900180 85 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
ion transmembrane transport GO:0034220 338 0.017
ribonucleoprotein complex biogenesis GO:0022613 116 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.016
release of cytochrome c from mitochondria GO:0001836 35 0.016
response to lipopolysaccharide GO:0032496 70 0.016
cell fate determination GO:0001709 3 0.016
spermatid differentiation GO:0048515 4 0.016
determination of adult lifespan GO:0008340 2 0.016
ion homeostasis GO:0050801 230 0.016
cellular response to virus GO:0098586 9 0.016
cellular protein complex assembly GO:0043623 188 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.015
ribonucleoprotein complex subunit organization GO:0071826 81 0.015
positive regulation of cell cycle GO:0045787 140 0.015
epithelial cell migration GO:0010631 119 0.015
negative regulation of rig i signaling pathway GO:0039536 2 0.015
negative regulation of protein secretion GO:0050709 29 0.015
regulation of transcription factor import into nucleus GO:0042990 39 0.015
response to abiotic stimulus GO:0009628 336 0.014
positive regulation of apoptotic signaling pathway GO:2001235 70 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
rna catabolic process GO:0006401 71 0.014
regulation of vasculature development GO:1901342 97 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
protein autoubiquitination GO:0051865 37 0.014
protein polymerization GO:0051258 71 0.014
cellular response to biotic stimulus GO:0071216 71 0.014
metal ion transport GO:0030001 272 0.014
macrophage fusion GO:0034238 1 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
ribonucleoprotein complex assembly GO:0022618 78 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
mrna metabolic process GO:0016071 175 0.014
positive regulation of transcription factor import into nucleus GO:0042993 25 0.014
cellular response to type i interferon GO:0071357 12 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
protein polyubiquitination GO:0000209 110 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.014
positive regulation of myeloid cell differentiation GO:0045639 39 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
ameboidal type cell migration GO:0001667 135 0.013
interferon gamma production GO:0032609 39 0.013
protein localization to organelle GO:0033365 280 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
single organism cellular localization GO:1902580 332 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
regulation of membrane potential GO:0042391 95 0.013
nuclear export GO:0051168 69 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
regulation of angiogenesis GO:0045765 92 0.013
protein modification by small protein removal GO:0070646 92 0.013
response to interferon beta GO:0035456 11 0.013
purine containing compound catabolic process GO:0072523 411 0.013
sequestering of metal ion GO:0051238 24 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
actin filament based process GO:0030029 224 0.013
positive regulation of mitochondrion organization GO:0010822 30 0.013
circulatory system development GO:0072359 262 0.013
gene silencing by rna GO:0031047 26 0.013
carbohydrate homeostasis GO:0033500 31 0.013
negative regulation of epithelial cell migration GO:0010633 38 0.013
calcium ion transport GO:0006816 147 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
positive regulation of intracellular transport GO:0032388 104 0.012
vasculature development GO:0001944 181 0.012
positive regulation of catabolic process GO:0009896 310 0.012
cation transport GO:0006812 331 0.012
signal transduction in response to dna damage GO:0042770 57 0.012
vesicle mediated transport GO:0016192 371 0.012
positive regulation of macrophage differentiation GO:0045651 7 0.012
negative regulation of binding GO:0051100 57 0.012
cell cycle arrest GO:0007050 71 0.012
regulation of ion homeostasis GO:2000021 73 0.012
regulation of anatomical structure size GO:0090066 101 0.012
regulation of cytokine production involved in immune response GO:0002718 22 0.012
negative regulation of kinase activity GO:0033673 106 0.012
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.012
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.012
spermatid development GO:0007286 4 0.012
negative regulation of secretion GO:0051048 58 0.012
mitotic cell cycle process GO:1903047 286 0.011
regulation of endothelial cell migration GO:0010594 67 0.011
melanin metabolic process GO:0006582 1 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
rna phosphodiester bond hydrolysis GO:0090501 35 0.011
negative regulation of viral release from host cell GO:1902187 12 0.011
response to radiation GO:0009314 151 0.011
protein ubiquitination GO:0016567 314 0.011
regulation of mapk cascade GO:0043408 262 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
positive regulation of response to biotic stimulus GO:0002833 18 0.011
cellular amino acid metabolic process GO:0006520 116 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
mitotic cell cycle GO:0000278 326 0.011
positive regulation of protein import into nucleus GO:0042307 46 0.011
negative regulation of catabolic process GO:0009895 104 0.011
regulation of ras protein signal transduction GO:0046578 155 0.010
regulation of cell differentiation GO:0045595 393 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010
ribonucleoside triphosphate catabolic process GO:0009203 391 0.010
regulation of cellular response to stress GO:0080135 244 0.010
positive regulation of protein localization to nucleus GO:1900182 48 0.010
negative regulation of ion transport GO:0043271 39 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
mitochondrion organization GO:0007005 156 0.010
negative regulation of dna binding GO:0043392 18 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
entry into host GO:0044409 25 0.010
negative regulation of cellular protein catabolic process GO:1903363 38 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010
glycoprotein biosynthetic process GO:0009101 91 0.010

IFI44 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.020
acquired metabolic disease DOID:0060158 58 0.020