Homo sapiens

7 known processes

ARHGEF6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

(Aliases: Cool-2,KIAA0006,COOL2,MRX46,alpha-PIX,PIXA,alphaPIX)

ARHGEF6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of fibroblast migration GO:0010763 3 0.250
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.116
Human
gtp catabolic process GO:0006184 237 0.102
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.097
post embryonic development GO:0009791 2 0.091
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.091
regulation of lamellipodium morphogenesis GO:2000392 4 0.090
Human
nucleoside catabolic process GO:0009164 408 0.087
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.084
Human
gtp metabolic process GO:0046039 239 0.083
Human
single organism membrane organization GO:0044802 268 0.079
mapk cascade GO:0000165 288 0.076
nucleotide catabolic process GO:0009166 408 0.075
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.073
purine nucleoside triphosphate metabolic process GO:0009144 412 0.070
Human
regulation of cell motility GO:2000145 299 0.065
Human
system process GO:0003008 349 0.065
negative regulation of protein metabolic process GO:0051248 391 0.064
membrane organization GO:0061024 292 0.061
regulation of cell migration GO:0030334 289 0.060
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.060
Human
transmembrane transport GO:0055085 399 0.059
regulation of cellular amine metabolic process GO:0033238 11 0.058
nucleoside phosphate catabolic process GO:1901292 412 0.056
Human
positive regulation of mapk cascade GO:0043410 190 0.056
organophosphate catabolic process GO:0046434 430 0.053
Human
regulation of peptidase activity GO:0052547 180 0.053
glycosyl compound catabolic process GO:1901658 413 0.052
Human
small gtpase mediated signal transduction GO:0007264 78 0.051
response to nitrogen compound GO:1901698 184 0.050
cellular amine metabolic process GO:0044106 41 0.050
locomotory behavior GO:0007626 1 0.050
regulation of intracellular transport GO:0032386 195 0.049
regulation of cytoskeleton organization GO:0051493 177 0.049
regulation of apoptotic signaling pathway GO:2001233 175 0.047
guanosine containing compound catabolic process GO:1901069 239 0.046
Human
multicellular organismal aging GO:0010259 3 0.045
regulation of cellular component movement GO:0051270 334 0.045
Human
positive regulation of cell death GO:0010942 263 0.045
Human
regeneration GO:0031099 4 0.044
regulation of establishment of protein localization GO:0070201 242 0.044
ras protein signal transduction GO:0007265 73 0.044
cellular response to oxygen containing compound GO:1901701 276 0.044
positive regulation of cell motility GO:2000147 177 0.044
Human
positive regulation of cellular component movement GO:0051272 181 0.043
Human
positive regulation of protein transport GO:0051222 135 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.043
Human
purine nucleoside catabolic process GO:0006152 398 0.043
Human
single organism cellular localization GO:1902580 332 0.043
regulation of protein transport GO:0051223 213 0.042
regulation of cellular response to stress GO:0080135 244 0.042
signal transduction by phosphorylation GO:0023014 297 0.041
protein localization to organelle GO:0033365 280 0.041
amine metabolic process GO:0009308 44 0.041
cell substrate junction assembly GO:0007044 35 0.041
Human
apoptotic signaling pathway GO:0097190 268 0.041
regulation of cell cycle GO:0051726 393 0.041
guanosine containing compound metabolic process GO:1901068 244 0.041
Human
mitotic cell cycle GO:0000278 326 0.041
purine nucleotide catabolic process GO:0006195 405 0.040
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.040
cellular macromolecular complex assembly GO:0034622 324 0.040
segmentation GO:0035282 4 0.040
glial cell migration GO:0008347 4 0.040
regulation of cellular component biogenesis GO:0044087 281 0.039
negative regulation of cell death GO:0060548 345 0.039
ameboidal type cell migration GO:0001667 135 0.039
Human
positive regulation of protein phosphorylation GO:0001934 313 0.039
cellular ketone metabolic process GO:0042180 80 0.039
regulation of protein localization GO:0032880 296 0.039
positive regulation of ras gtpase activity GO:0032320 117 0.039
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.039
purine ribonucleoside catabolic process GO:0046130 398 0.038
Human
regulation of endopeptidase activity GO:0052548 170 0.038
regulation of proteolysis GO:0030162 293 0.037
nucleoside triphosphate catabolic process GO:0009143 394 0.036
Human
organelle inheritance GO:0048308 2 0.036
positive regulation of hydrolase activity GO:0051345 331 0.036
Human
neuron projection regeneration GO:0031102 1 0.036
oogenesis GO:0048477 2 0.036
activation of mapkkk activity GO:0000185 7 0.035
actin filament based process GO:0030029 224 0.035
extrinsic apoptotic signaling pathway GO:0097191 119 0.035
lipid localization GO:0010876 106 0.034
regulation of mitotic cell cycle GO:0007346 189 0.034
determination of adult lifespan GO:0008340 2 0.034
positive regulation of phosphorylation GO:0042327 394 0.034
positive regulation of apoptotic process GO:0043065 246 0.034
Human
nucleocytoplasmic transport GO:0006913 176 0.033
positive regulation of actin filament bundle assembly GO:0032233 25 0.033
positive regulation of transferase activity GO:0051347 227 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.033
Human
purine ribonucleoside metabolic process GO:0046128 437 0.032
Human
regulation of cytoplasmic transport GO:1903649 149 0.032
neuromuscular junction development GO:0007528 3 0.032
lipid transport GO:0006869 90 0.032
stress activated mapk cascade GO:0051403 93 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.031
regulation of cell differentiation GO:0045595 393 0.031
Human
intracellular protein transport GO:0006886 270 0.031
regulation of cell cycle process GO:0010564 266 0.031
negative regulation of apoptotic process GO:0043066 316 0.031
keratinization GO:0031424 2 0.030
multicellular organismal response to stress GO:0033555 1 0.030
organelle assembly GO:0070925 176 0.030
positive regulation of transport GO:0051050 336 0.030
regulation of protein processing GO:0070613 150 0.030
cell junction organization GO:0034330 79 0.030
Human
wound healing GO:0042060 115 0.029
cellular component morphogenesis GO:0032989 314 0.029
Human
positive regulation of cellular component organization GO:0051130 376 0.029
Human
female gamete generation GO:0007292 2 0.029
protein autophosphorylation GO:0046777 123 0.029
positive regulation of gtp catabolic process GO:0033126 166 0.029
Human
cellular lipid metabolic process GO:0044255 303 0.029
positive regulation of cell migration GO:0030335 172 0.028
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.028
Human
regulation of gtpase activity GO:0043087 180 0.028
Human
rhythmic behavior GO:0007622 2 0.028
regulation of protein kinase activity GO:0045859 289 0.028
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.027
organ formation GO:0048645 3 0.027
peptidyl tyrosine phosphorylation GO:0018108 170 0.027
cell matrix adhesion GO:0007160 85 0.027
Human
peptidyl tyrosine modification GO:0018212 170 0.027
sterol transmembrane transport GO:0035382 4 0.027
cell division GO:0051301 168 0.027
ribonucleoprotein complex assembly GO:0022618 78 0.027
cell projection organization GO:0030030 252 0.027
Human Mouse
regulation of kinase activity GO:0043549 314 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
rna processing GO:0006396 255 0.027
negative regulation of hydrolase activity GO:0051346 182 0.026
mitotic cell cycle process GO:1903047 286 0.026
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.026
negative regulation of endopeptidase activity GO:0010951 84 0.026
mating GO:0007618 1 0.026
regulation of cysteine type endopeptidase activity GO:2000116 127 0.026
cell adhesion GO:0007155 325 0.026
Human
neuron fate commitment GO:0048663 2 0.026
inner ear morphogenesis GO:0042472 4 0.026
nuclear transport GO:0051169 179 0.026
positive regulation of intracellular protein transport GO:0090316 76 0.026
cellular response to abiotic stimulus GO:0071214 117 0.025
positive regulation of cell adhesion GO:0045785 84 0.025
Human
cellular amino acid metabolic process GO:0006520 116 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
regulation of anatomical structure morphogenesis GO:0022603 286 0.025
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.025
regulation of protein localization to nucleus GO:1900180 85 0.025
defense response GO:0006952 315 0.024
response to wounding GO:0009611 168 0.024
response to organonitrogen compound GO:0010243 156 0.024
sterol transport GO:0015918 39 0.024
purine containing compound catabolic process GO:0072523 411 0.024
Human
cell substrate adhesion GO:0031589 132 0.024
Human
cell junction assembly GO:0034329 67 0.024
Human
negative regulation of proteolysis GO:0045861 132 0.024
positive regulation of intracellular transport GO:0032388 104 0.024
protein processing GO:0016485 226 0.024
negative regulation of protein processing GO:0010955 142 0.024
protein catabolic process GO:0030163 325 0.024
hematopoietic or lymphoid organ development GO:0048534 186 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
ribonucleoprotein complex biogenesis GO:0022613 116 0.023
hemopoiesis GO:0030097 180 0.023
regulation of actin cytoskeleton organization GO:0032956 116 0.023
negative regulation of peptidase activity GO:0010466 91 0.023
forebrain neuron differentiation GO:0021879 3 0.023
ion transmembrane transport GO:0034220 338 0.023
maintenance of location GO:0051235 112 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
Human
positive regulation of cellular catabolic process GO:0031331 284 0.023
Human
oocyte development GO:0048599 1 0.023
dephosphorylation GO:0016311 209 0.023
motor neuron axon guidance GO:0008045 2 0.022
protein maturation GO:0051604 233 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
regulation of peptidyl serine phosphorylation GO:0033135 50 0.022
regulation of rho protein signal transduction GO:0035023 79 0.022
Human
midgut development GO:0007494 1 0.022
positive regulation of kinase activity GO:0033674 204 0.022
vacuole organization GO:0007033 44 0.022
positive regulation of catabolic process GO:0009896 310 0.022
Human
response to decreased oxygen levels GO:0036293 96 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
Human
regulation of small gtpase mediated signal transduction GO:0051056 156 0.022
Human
regulation of mapk cascade GO:0043408 262 0.022
growth GO:0040007 202 0.022
biological adhesion GO:0022610 331 0.022
Human
positive regulation of cytoplasmic transport GO:1903651 82 0.022
protein targeting GO:0006605 187 0.022
protein localization to membrane GO:0072657 160 0.022
negative regulation of protein modification process GO:0031400 200 0.022
salivary gland morphogenesis GO:0007435 4 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
tripartite regional subdivision GO:0007351 2 0.021
ribonucleoprotein complex subunit organization GO:0071826 81 0.021
regulation of intracellular protein transport GO:0033157 123 0.021
cellular protein complex assembly GO:0043623 188 0.021
forebrain generation of neurons GO:0021872 3 0.021
regulation of protein complex assembly GO:0043254 147 0.021
positive regulation of immune system process GO:0002684 283 0.021
circadian behavior GO:0048512 2 0.021
regulation of secretion GO:0051046 194 0.021
protein localization to nucleus GO:0034504 136 0.021
lipid metabolic process GO:0006629 381 0.021
protein import GO:0017038 130 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
Human
positive regulation of programmed cell death GO:0043068 249 0.021
Human
hindbrain development GO:0030902 3 0.021
negative regulation of programmed cell death GO:0043069 321 0.020
stress activated protein kinase signaling cascade GO:0031098 94 0.020
positive regulation of immune response GO:0050778 159 0.020
regulation of mitosis GO:0007088 63 0.020
muscle structure development GO:0061061 98 0.020
regulation of cardiac muscle cell proliferation GO:0060043 4 0.020
negative regulation of protein maturation GO:1903318 142 0.020
cardiac muscle cell contraction GO:0086003 4 0.020
regulation of binding GO:0051098 111 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.020
cell growth GO:0016049 160 0.020
fibroblast migration GO:0010761 7 0.020
Human
plasma membrane organization GO:0007009 115 0.020
response to oxygen containing compound GO:1901700 369 0.020
regulation of cell development GO:0060284 161 0.020
Human
generation of neurons GO:0048699 152 0.020
nuclear division GO:0000280 128 0.020
positive regulation of protein localization to nucleus GO:1900182 48 0.019
epithelium development GO:0060429 227 0.019
regulation of cell substrate adhesion GO:0010810 68 0.019
Human
organelle fission GO:0048285 149 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
protein polymerization GO:0051258 71 0.019
stress fiber assembly GO:0043149 40 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
regulation of cell division GO:0051302 116 0.019
blood circulation GO:0008015 113 0.019
regulation of protein polymerization GO:0032271 63 0.019
astrocyte cell migration GO:0043615 1 0.019
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.019
single organism nuclear import GO:1902593 104 0.019
positive regulation of defense response GO:0031349 87 0.019
spermatid differentiation GO:0048515 4 0.019
response to inorganic substance GO:0010035 127 0.019
regulation of protein maturation GO:1903317 150 0.019
cellular response to nitrogen compound GO:1901699 144 0.019
positive regulation of synapse structural plasticity GO:0051835 2 0.019
ribonucleotide catabolic process GO:0009261 405 0.018
Human
forebrain neuron development GO:0021884 2 0.018
response to abiotic stimulus GO:0009628 336 0.018
cation transport GO:0006812 331 0.018
peptidyl serine phosphorylation GO:0018105 101 0.018
regulation of actin filament bundle assembly GO:0032231 36 0.018
response to oxygen levels GO:0070482 100 0.018
positive regulation of cytokine production GO:0001819 167 0.018
single organism cell adhesion GO:0098602 179 0.018
Human
regulation of transferase activity GO:0051338 355 0.018
chemotaxis GO:0006935 157 0.018
positive regulation of map kinase activity GO:0043406 80 0.018
regulation of membrane potential GO:0042391 95 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.018
Human
response to peptide GO:1901652 65 0.018
nuclear migration GO:0007097 1 0.018
activation of protein kinase activity GO:0032147 90 0.018
positive regulation of protein kinase activity GO:0045860 190 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
response to external biotic stimulus GO:0043207 261 0.018
metal ion transport GO:0030001 272 0.018
organic hydroxy compound transport GO:0015850 63 0.018
axon regeneration GO:0031103 1 0.018
immune system development GO:0002520 195 0.018
positive regulation of stress activated mapk cascade GO:0032874 60 0.018
cell morphogenesis GO:0000902 296 0.018
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.018
tissue regeneration GO:0042246 3 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
blastoderm segmentation GO:0007350 2 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
positive regulation of locomotion GO:0040017 186 0.017
Human
response to hypoxia GO:0001666 96 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
Human
mrna metabolic process GO:0016071 175 0.017
anterior posterior axis specification embryo GO:0008595 2 0.017
regulation of nucleocytoplasmic transport GO:0046822 98 0.017
striated muscle contraction GO:0006941 52 0.017
histone modification GO:0016570 251 0.017
ion homeostasis GO:0050801 230 0.017
regulation of neurotransmitter secretion GO:0046928 3 0.017
positive regulation of protein import into nucleus GO:0042307 46 0.017
spermatid development GO:0007286 4 0.017
specification of organ identity GO:0010092 3 0.017
regulation of nuclear division GO:0051783 65 0.016
actin filament bundle assembly GO:0051017 54 0.016
positive regulation of organelle organization GO:0010638 195 0.016
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.016
response to organic cyclic compound GO:0014070 204 0.016
negative regulation of apoptotic signaling pathway GO:2001234 97 0.016
regulation of stress activated mapk cascade GO:0032872 84 0.016
adult locomotory behavior GO:0008344 1 0.016
intracellular receptor signaling pathway GO:0030522 104 0.016
mitotic nuclear division GO:0007067 119 0.016
regulation of meiotic cell cycle GO:0051445 4 0.016
actin filament organization GO:0007015 128 0.016
cell migration involved in gastrulation GO:0042074 1 0.016
vesicle mediated transport GO:0016192 371 0.016
immune effector process GO:0002252 159 0.016
cerebral cortex radially oriented cell migration GO:0021799 1 0.016
positive regulation of apoptotic signaling pathway GO:2001235 70 0.016
actin filament bundle organization GO:0061572 54 0.016
hair cell differentiation GO:0035315 2 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
innate immune response GO:0045087 178 0.016
actin cytoskeleton organization GO:0030036 207 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
Human
positive regulation of behavior GO:0048520 60 0.016
muscle contraction GO:0006936 73 0.016
contact inhibition GO:0060242 3 0.016
regulation of response to external stimulus GO:0032101 222 0.015
heart formation GO:0060914 2 0.015
cerebral cortex cell migration GO:0021795 3 0.015
cytoplasmic transport GO:0016482 379 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
Human
reactive oxygen species biosynthetic process GO:1903409 4 0.015
neuroblast proliferation GO:0007405 4 0.015
t cell activation GO:0042110 99 0.015
cell development GO:0048468 328 0.015
Human
activation of immune response GO:0002253 114 0.015
metencephalon development GO:0022037 2 0.015
associative learning GO:0008306 1 0.015
sequestering of calcium ion GO:0051208 17 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
sequestering of metal ion GO:0051238 24 0.015
regulation of protein catabolic process GO:0042176 155 0.015
immune response GO:0006955 307 0.015
regulation of cytokine production GO:0001817 232 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
establishment of tissue polarity GO:0007164 3 0.014
oocyte differentiation GO:0009994 2 0.014
muscle cell fate commitment GO:0042693 4 0.014
wnt signaling pathway GO:0016055 156 0.014
regulation of dephosphorylation GO:0035303 96 0.014
embryo development GO:0009790 123 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
Human
taxis GO:0042330 157 0.014
cellular response to peptide hormone stimulus GO:0071375 56 0.014
cell cell junction organization GO:0045216 69 0.014
Human
cell projection assembly GO:0030031 126 0.014
Mouse
covalent chromatin modification GO:0016569 254 0.014
tissue morphogenesis GO:0048729 96 0.014
jnk cascade GO:0007254 80 0.014
response to virus GO:0009615 126 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
cochlea development GO:0090102 1 0.014
cation transmembrane transport GO:0098655 238 0.014
cell projection morphogenesis GO:0048858 129 0.014
Human
response to lipid GO:0033993 206 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
regulation of actin filament length GO:0030832 56 0.014
limbic system development GO:0021761 3 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
Human
somatic muscle development GO:0007525 1 0.014
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
sensory perception GO:0007600 103 0.013
blood vessel development GO:0001568 172 0.013
response to fungus GO:0009620 4 0.013
protein targeting to nucleus GO:0044744 104 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
Human
positive regulation of endothelial cell migration GO:0010595 39 0.013
regulation of ion transport GO:0043269 189 0.013
myoblast fusion GO:0007520 1 0.013
regulation of heart growth GO:0060420 4 0.013
positive regulation of developmental process GO:0051094 314 0.013
Human
regulation of locomotion GO:0040012 329 0.013
Human
positive regulation of pseudopodium assembly GO:0031274 7 0.013
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 5 0.013
neurogenesis GO:0022008 169 0.013
cation homeostasis GO:0055080 189 0.013
ectodermal placode development GO:0071696 1 0.013
negative regulation of transferase activity GO:0051348 124 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
Human
cellular response to dna damage stimulus GO:0006974 379 0.013
neuron projection development GO:0031175 106 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.013
nucleus localization GO:0051647 1 0.013
response to other organism GO:0051707 261 0.013
cerebellum development GO:0021549 2 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
cell fate determination GO:0001709 3 0.013
substrate adhesion dependent cell spreading GO:0034446 41 0.013
Human
positive regulation of lymphocyte activation GO:0051251 73 0.013
nuclear import GO:0051170 106 0.013
regulation of map kinase activity GO:0043405 108 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
peripheral nervous system development GO:0007422 2 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
regulation of cell growth GO:0001558 135 0.013
compound eye development GO:0048749 1 0.013
response to hormone GO:0009725 175 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
divalent metal ion transport GO:0070838 152 0.013
small molecule biosynthetic process GO:0044283 157 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
establishment of planar polarity GO:0001736 3 0.013
protein import into nucleus GO:0006606 104 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
cellular response to hormone stimulus GO:0032870 125 0.012
myosin filament assembly GO:0031034 2 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.012
visual behavior GO:0007632 2 0.012
response to insulin GO:0032868 45 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
positive regulation of cell cycle GO:0045787 140 0.012
protein localization to plasma membrane GO:0072659 93 0.012
secretion GO:0046903 254 0.012
response to growth factor GO:0070848 205 0.012
metal ion homeostasis GO:0055065 169 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
regulation of protein import into nucleus GO:0042306 78 0.012
regulation of cell adhesion GO:0030155 166 0.012
Human
muscle system process GO:0003012 81 0.012
anion transport GO:0006820 161 0.012
somatic stem cell maintenance GO:0035019 4 0.012
sensory perception of mechanical stimulus GO:0050954 37 0.012
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.012
negative regulation of kinase activity GO:0033673 106 0.012
cellular component disassembly GO:0022411 92 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.012
actin mediated cell contraction GO:0070252 12 0.012
cellular macromolecule catabolic process GO:0044265 380 0.012
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.012
regulation of nervous system development GO:0051960 88 0.012
actomyosin structure organization GO:0031032 59 0.012
calcium ion transmembrane transport GO:0070588 76 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.012
copulation GO:0007620 1 0.012
lipid biosynthetic process GO:0008610 177 0.012
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
cellular chemical homeostasis GO:0055082 180 0.012
circulatory system development GO:0072359 262 0.012
positive regulation of cell substrate adhesion GO:0010811 37 0.012
Human
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
blastocyst development GO:0001824 3 0.011
phospholipid metabolic process GO:0006644 99 0.011
response to oxidative stress GO:0006979 121 0.011
actin polymerization or depolymerization GO:0008154 56 0.011
endosomal transport GO:0016197 129 0.011
epithelium migration GO:0090132 119 0.011
actin filament based movement GO:0030048 17 0.011
response to peptide hormone GO:0043434 61 0.011
dna repair GO:0006281 198 0.011
regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis GO:2001270 3 0.011
ectodermal placode formation GO:0060788 1 0.011
regulation of secretion by cell GO:1903530 177 0.011
nitrogen compound transport GO:0071705 191 0.011
cellular amide metabolic process GO:0043603 69 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
regulation of actin polymerization or depolymerization GO:0008064 56 0.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.011
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 11 0.011
regulation of multi organism process GO:0043900 157 0.011
semaphorin plexin signaling pathway GO:0071526 4 0.011
rna splicing GO:0008380 131 0.011

ARHGEF6 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.049
disease of metabolism DOID:0014667 295 0.024
muscular disease DOID:0080000 114 0.023
myopathy DOID:423 104 0.021
muscle tissue disease DOID:66 113 0.021
sensory system disease DOID:0050155 203 0.019
eye and adnexa disease DOID:1492 150 0.019
nervous system disease DOID:863 431 0.019
eye disease DOID:5614 149 0.019
connective tissue disease DOID:65 109 0.018
central nervous system disease DOID:331 186 0.016
inherited metabolic disorder DOID:655 242 0.015
heart disease DOID:114 68 0.014
cardiomyopathy DOID:0050700 50 0.014
intrinsic cardiomyopathy DOID:0060036 50 0.014
cardiovascular system disease DOID:1287 106 0.014
bone disease DOID:0080001 88 0.013
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
retinal disease DOID:5679 118 0.013
muscular dystrophy DOID:9884 51 0.012