Homo sapiens

0 known processes

ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

(Aliases: SUB1.5,LBCL2,LSC,P115-RHOGEF,GEF1)

ARHGEF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rho protein signal transduction GO:0007266 26 0.651
Human Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.354
Fly
ras protein signal transduction GO:0007265 73 0.349
Human Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.297
Fly
regulation of gtpase activity GO:0043087 180 0.209
Fly
ribonucleoside catabolic process GO:0042454 406 0.202
Fly
guanosine containing compound metabolic process GO:1901068 244 0.199
Fly
post embryonic development GO:0009791 2 0.196
Fly
circadian behavior GO:0048512 2 0.186
purine ribonucleotide catabolic process GO:0009154 404 0.186
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.185
Fly
organophosphate catabolic process GO:0046434 430 0.178
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.177
glycosyl compound catabolic process GO:1901658 413 0.175
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.174
Fly
regulation of nucleotide catabolic process GO:0030811 205 0.172
Fly
purine nucleoside catabolic process GO:0006152 398 0.171
Fly
amine metabolic process GO:0009308 44 0.170
positive regulation of nucleotide catabolic process GO:0030813 185 0.168
Fly
cellular amino acid metabolic process GO:0006520 116 0.168
positive regulation of catabolic process GO:0009896 310 0.167
Fly
actin cytoskeleton organization GO:0030036 207 0.167
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.163
Fly
ameboidal type cell migration GO:0001667 135 0.156
nucleotide catabolic process GO:0009166 408 0.156
Fly
cell morphogenesis GO:0000902 296 0.155
Fly
cellular ketone metabolic process GO:0042180 80 0.146
positive regulation of phosphorylation GO:0042327 394 0.146
small gtpase mediated signal transduction GO:0007264 78 0.141
Human Fly
cell development GO:0048468 328 0.140
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.140
regulation of cellular ketone metabolic process GO:0010565 50 0.138
purine nucleotide catabolic process GO:0006195 405 0.137
Fly
regulation of nucleoside metabolic process GO:0009118 209 0.133
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.133
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.131
Fly
rhythmic behavior GO:0007622 2 0.130
somatic stem cell maintenance GO:0035019 4 0.125
mapk cascade GO:0000165 288 0.124
cellular amine metabolic process GO:0044106 41 0.123
purine nucleoside triphosphate catabolic process GO:0009146 392 0.122
Fly
regulation of cell motility GO:2000145 299 0.115
positive regulation of nucleotide metabolic process GO:0045981 230 0.114
Fly
nervous system development GO:0007399 293 0.111
Fly
negative regulation of cell fate commitment GO:0010454 3 0.109
circulatory system development GO:0072359 262 0.108
positive regulation of protein phosphorylation GO:0001934 313 0.106
purine ribonucleoside catabolic process GO:0046130 398 0.103
Fly
positive regulation of nucleoside metabolic process GO:0045979 186 0.102
Fly
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.102
system process GO:0003008 349 0.101
Worm
positive regulation of cellular amine metabolic process GO:0033240 7 0.100
regulation of cell morphogenesis GO:0022604 153 0.099
Fly
positive regulation of gtpase activity GO:0043547 166 0.098
Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.097
Fly
response to cocaine GO:0042220 1 0.095
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.095
regulation of rho protein signal transduction GO:0035023 79 0.095
Fly
cellular component morphogenesis GO:0032989 314 0.094
Fly
positive regulation of map kinase activity GO:0043406 80 0.094
response to abiotic stimulus GO:0009628 336 0.094
Worm
regulation of nucleotide metabolic process GO:0006140 269 0.092
Fly
regulation of locomotion GO:0040012 329 0.092
cell adhesion GO:0007155 325 0.091
gtp catabolic process GO:0006184 237 0.090
Fly
female gamete generation GO:0007292 2 0.090
positive regulation of ras gtpase activity GO:0032320 117 0.089
Fly
regulation of mapk cascade GO:0043408 262 0.089
regulation of cellular component biogenesis GO:0044087 281 0.088
guanosine containing compound catabolic process GO:1901069 239 0.086
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.085
Fly
salivary gland morphogenesis GO:0007435 4 0.083
positive regulation of transferase activity GO:0051347 227 0.083
oogenesis GO:0048477 2 0.082
nucleoside monophosphate metabolic process GO:0009123 191 0.082
signal transduction by phosphorylation GO:0023014 297 0.080
regulation of cellular amine metabolic process GO:0033238 11 0.079
stress activated protein kinase signaling cascade GO:0031098 94 0.078
negative regulation of phosphorus metabolic process GO:0010563 267 0.078
regulation of epithelial cell migration GO:0010632 93 0.078
biological adhesion GO:0022610 331 0.076
actin mediated cell contraction GO:0070252 12 0.075
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.075
Fly
regulation of jnk cascade GO:0046328 73 0.075
actin filament based process GO:0030029 224 0.075
Fly
regulation of small gtpase mediated signal transduction GO:0051056 156 0.075
Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.075
Fly
locomotory behavior GO:0007626 1 0.074
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.074
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.074
Fly
negative regulation of multicellular organismal process GO:0051241 317 0.073
positive regulation of mapk cascade GO:0043410 190 0.073
cellular macromolecule catabolic process GO:0044265 380 0.071
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.071
neurological system process GO:0050877 163 0.071
Worm
regulation of kinase activity GO:0043549 314 0.070
positive regulation of jnk cascade GO:0046330 52 0.070
regulation of cellular component movement GO:0051270 334 0.070
ribonucleoside monophosphate metabolic process GO:0009161 187 0.069
growth GO:0040007 202 0.068
Fly
regulation of cell migration GO:0030334 289 0.068
positive regulation of gtp catabolic process GO:0033126 166 0.067
Fly
purine containing compound catabolic process GO:0072523 411 0.067
Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.066
digestive system development GO:0055123 75 0.065
Fly
regulation of gtp catabolic process GO:0033124 180 0.065
Fly
cell projection organization GO:0030030 252 0.064
Fly
ribonucleotide catabolic process GO:0009261 405 0.064
Fly
nucleoside catabolic process GO:0009164 408 0.064
Fly
regulation of ras gtpase activity GO:0032318 128 0.063
Fly
jnk cascade GO:0007254 80 0.062
negative regulation of developmental process GO:0051093 247 0.061
purine ribonucleoside metabolic process GO:0046128 437 0.061
Fly
regulation of proteolysis GO:0030162 293 0.057
regulation of protein kinase activity GO:0045859 289 0.056
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.056
epithelial cell migration GO:0010631 119 0.055
actin filament organization GO:0007015 128 0.054
Fly
adult locomotory behavior GO:0008344 1 0.053
positive regulation of kinase activity GO:0033674 204 0.053
negative regulation of cell differentiation GO:0045596 171 0.052
cardiovascular system development GO:0072358 262 0.051
regulation of actin cytoskeleton organization GO:0032956 116 0.050
regulation of stress activated mapk cascade GO:0032872 84 0.050
regulation of protein serine threonine kinase activity GO:0071900 179 0.049
response to oxygen containing compound GO:1901700 369 0.049
organ formation GO:0048645 3 0.049
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.049
purine nucleoside monophosphate metabolic process GO:0009126 186 0.048
epithelial cell differentiation GO:0030855 141 0.048
atp catabolic process GO:0006200 157 0.048
endocrine process GO:0050886 25 0.047
positive regulation of developmental process GO:0051094 314 0.047
regulation of map kinase activity GO:0043405 108 0.047
ubiquitin dependent protein catabolic process GO:0006511 206 0.046
purine nucleoside monophosphate catabolic process GO:0009128 158 0.046
histone modification GO:0016570 251 0.046
positive regulation of protein kinase activity GO:0045860 190 0.046
peptidyl tyrosine phosphorylation GO:0018108 170 0.045
nucleoside monophosphate catabolic process GO:0009125 159 0.045
actin filament based movement GO:0030048 17 0.045
Fly
protein autophosphorylation GO:0046777 123 0.044
segmentation GO:0035282 4 0.044
atp metabolic process GO:0046034 176 0.044
regulation of embryonic development GO:0045995 20 0.044
Fly
negative regulation of phosphorylation GO:0042326 174 0.043
positive regulation of locomotion GO:0040017 186 0.043
chromatin modification GO:0016568 298 0.043
lamellipodium organization GO:0097581 30 0.043
chromatin organization GO:0006325 351 0.043
positive regulation of hydrolase activity GO:0051345 331 0.043
Fly
actin filament bundle organization GO:0061572 54 0.042
regulation of cellular response to stress GO:0080135 244 0.042
regulation of rho gtpase activity GO:0032319 66 0.042
Fly
regulation of proteasomal protein catabolic process GO:0061136 87 0.041
meiotic chromosome segregation GO:0045132 4 0.041
memory GO:0007613 3 0.041
regulation of defense response GO:0031347 154 0.041
single organism cell adhesion GO:0098602 179 0.040
histone acetylation GO:0016573 93 0.040
negative regulation of catalytic activity GO:0043086 335 0.040
cellular macromolecular complex assembly GO:0034622 324 0.040
cell division GO:0051301 168 0.040
covalent chromatin modification GO:0016569 254 0.039
regulation of response to external stimulus GO:0032101 222 0.039
cell migration involved in gastrulation GO:0042074 1 0.039
cell fate determination GO:0001709 3 0.039
cell projection assembly GO:0030031 126 0.038
regulation of actin filament based process GO:0032970 141 0.038
modification dependent protein catabolic process GO:0019941 209 0.038
response to radiation GO:0009314 151 0.037
response to nitrogen compound GO:1901698 184 0.037
positive regulation of stress activated mapk cascade GO:0032874 60 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.037
taxis GO:0042330 157 0.036
regulation of cell cycle GO:0051726 393 0.036
enzyme linked receptor protein signaling pathway GO:0007167 303 0.036
negative regulation of epithelial cell migration GO:0010633 38 0.036
multicellular organismal aging GO:0010259 3 0.036
regulation of transferase activity GO:0051338 355 0.036
neuromuscular junction development GO:0007528 3 0.035
determination of adult lifespan GO:0008340 2 0.035
epithelium development GO:0060429 227 0.035
Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
metal ion transport GO:0030001 272 0.034
positive regulation of cellular component organization GO:0051130 376 0.034
wnt signaling pathway GO:0016055 156 0.034
cell junction organization GO:0034330 79 0.034
actin filament bundle assembly GO:0051017 54 0.033
tissue migration GO:0090130 119 0.033
cellular protein catabolic process GO:0044257 261 0.033
cell part morphogenesis GO:0032990 137 0.033
Fly
regulation of cell differentiation GO:0045595 393 0.033
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.033
Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.032
Fly
negative regulation of cell migration GO:0030336 102 0.032
negative regulation of protein phosphorylation GO:0001933 140 0.032
negative regulation of cellular component movement GO:0051271 106 0.032
cell growth GO:0016049 160 0.032
Fly
single organism membrane organization GO:0044802 268 0.032
regulation of cellular protein catabolic process GO:1903362 96 0.032
microtubule cytoskeleton organization GO:0000226 176 0.032
digestive tract development GO:0048565 75 0.032
Fly
regulation of organ formation GO:0003156 4 0.032
regulation of ras protein signal transduction GO:0046578 155 0.031
Fly
tube development GO:0035295 125 0.031
Fly
single organism cellular localization GO:1902580 332 0.031
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.030
heart formation GO:0060914 2 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
organ induction GO:0001759 4 0.030
protein oligomerization GO:0051259 173 0.030
regulation of protein catabolic process GO:0042176 155 0.030
regulation of cell cycle process GO:0010564 266 0.030
internal protein amino acid acetylation GO:0006475 101 0.030
cellular protein complex assembly GO:0043623 188 0.030
cdc42 protein signal transduction GO:0032488 4 0.030
positive regulation of rho gtpase activity GO:0032321 56 0.029
Fly
behavior GO:0007610 112 0.029
Worm
cytoplasmic transport GO:0016482 379 0.029
epithelium migration GO:0090132 119 0.029
positive regulation of cell migration GO:0030335 172 0.029
regulation of cardioblast differentiation GO:0051890 4 0.029
heart field specification GO:0003128 2 0.029
morphogenesis of an epithelium GO:0002009 60 0.029
Fly
positive regulation of cell motility GO:2000147 177 0.029
response to wounding GO:0009611 168 0.028
negative regulation of cell death GO:0060548 345 0.028
Rat
regulation of cytoskeleton organization GO:0051493 177 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.028
regulation of microtubule based process GO:0032886 74 0.028
protein catabolic process GO:0030163 325 0.028
regulation of wnt signaling pathway GO:0030111 123 0.028
regulation of protein localization GO:0032880 296 0.028
internal peptidyl lysine acetylation GO:0018393 97 0.027
stress activated mapk cascade GO:0051403 93 0.027
motor neuron axon guidance GO:0008045 2 0.027
negative regulation of protein modification process GO:0031400 200 0.027
dephosphorylation GO:0016311 209 0.027
phototransduction GO:0007602 3 0.027
proteasomal protein catabolic process GO:0010498 176 0.027
cell projection morphogenesis GO:0048858 129 0.027
Fly
i kappab kinase nf kappab signaling GO:0007249 166 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
modification dependent macromolecule catabolic process GO:0043632 212 0.027
protein homooligomerization GO:0051260 100 0.026
cell substrate adhesion GO:0031589 132 0.026
regulation of microtubule cytoskeleton organization GO:0070507 61 0.026
postsynaptic membrane organization GO:0001941 2 0.026
chemical homeostasis GO:0048878 306 0.026
membrane organization GO:0061024 292 0.025
sulfur compound metabolic process GO:0006790 101 0.025
rna processing GO:0006396 255 0.025
negative regulation of locomotion GO:0040013 118 0.025
tube closure GO:0060606 3 0.025
regulation of canonical wnt signaling pathway GO:0060828 88 0.024
cation transport GO:0006812 331 0.024
ion homeostasis GO:0050801 230 0.024
endothelial cell migration GO:0043542 86 0.024
regulation of jun kinase activity GO:0043506 27 0.024
gtp metabolic process GO:0046039 239 0.024
Fly
response to drug GO:0042493 81 0.024
peptidyl tyrosine modification GO:0018212 170 0.024
hindbrain development GO:0030902 3 0.023
regulation of growth GO:0040008 165 0.023
peptidyl lysine modification GO:0018205 144 0.023
regulation of protein complex assembly GO:0043254 147 0.023
mitotic cell cycle process GO:1903047 286 0.023
cation homeostasis GO:0055080 189 0.023
maintenance of location GO:0051235 112 0.023
neuroblast proliferation GO:0007405 4 0.023
mitotic cell cycle GO:0000278 326 0.023
intracellular protein transport GO:0006886 270 0.023
morphogenesis of embryonic epithelium GO:0016331 4 0.023
Fly
regulation of cell projection organization GO:0031344 107 0.022
Fly
negative regulation of hydrolase activity GO:0051346 182 0.022
regulation of cell shape GO:0008360 48 0.022
Fly
generation of neurons GO:0048699 152 0.022
Fly
regulation of mitotic cell cycle GO:0007346 189 0.022
neuron differentiation GO:0030182 138 0.022
Fly
cardiac cell fate specification GO:0060912 1 0.022
negative regulation of cell motility GO:2000146 104 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
steroid hormone secretion GO:0035929 8 0.022
protein localization to nucleus GO:0034504 136 0.021
canonical wnt signaling pathway GO:0060070 116 0.021
heart morphogenesis GO:0003007 48 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
regulation of cell adhesion GO:0030155 166 0.021
sensory perception GO:0007600 103 0.021
Worm
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.021
dna repair GO:0006281 198 0.021
developmental growth GO:0048589 48 0.021
Fly
microtubule based process GO:0007017 210 0.021
protein localization to membrane GO:0072657 160 0.020
morphogenesis of a polarized epithelium GO:0001738 3 0.020
protein acylation GO:0043543 138 0.020
muscle contraction GO:0006936 73 0.020
negative regulation of cell cycle GO:0045786 193 0.020
sex determination GO:0007530 3 0.020
mitotic nuclear division GO:0007067 119 0.020
tube morphogenesis GO:0035239 95 0.020
Fly
nerve development GO:0021675 4 0.020
meiosis i GO:0007127 4 0.020
vesicle mediated transport GO:0016192 371 0.020
response to inorganic substance GO:0010035 127 0.020
activation of mapk activity GO:0000187 45 0.020
regulation of heart morphogenesis GO:2000826 4 0.020
negative regulation of transferase activity GO:0051348 124 0.020
regulation of vesicle mediated transport GO:0060627 130 0.020
regulation of heart induction GO:0090381 2 0.019
protein processing GO:0016485 226 0.019
g protein coupled receptor signaling pathway GO:0007186 207 0.019
Human
regulation of cell development GO:0060284 161 0.019
Fly
cellular homeostasis GO:0019725 196 0.019
response to organic cyclic compound GO:0014070 204 0.019
retinal ganglion cell axon guidance GO:0031290 2 0.019
regulation of dephosphorylation GO:0035303 96 0.019
ribonucleoside monophosphate catabolic process GO:0009158 158 0.019
cell matrix adhesion GO:0007160 85 0.019
cell junction assembly GO:0034329 67 0.019
positive regulation of cell development GO:0010720 92 0.019
protein localization to organelle GO:0033365 280 0.019
regulation of tor signaling GO:0032006 30 0.019
regulation of cardiac cell fate specification GO:2000043 1 0.019
unidimensional cell growth GO:0009826 1 0.018
Fly
defense response GO:0006952 315 0.018
epithelial cell development GO:0002064 34 0.018
regulation of dna metabolic process GO:0051052 153 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.018
chromosome segregation GO:0007059 114 0.018
regeneration GO:0031099 4 0.018
activation of protein kinase activity GO:0032147 90 0.018
secretion by cell GO:0032940 226 0.018
embryo development GO:0009790 123 0.018
Worm Fly
convergent extension GO:0060026 1 0.018
nuclear transport GO:0051169 179 0.018
heart development GO:0007507 95 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
protein acetylation GO:0006473 116 0.018
oocyte development GO:0048599 1 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
neural tube closure GO:0001843 3 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
regulation of secretion by cell GO:1903530 177 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
digestive tract morphogenesis GO:0048546 56 0.017
Fly
response to cytokine GO:0034097 232 0.017
positive regulation of jun kinase activity GO:0043507 23 0.017
cation transmembrane transport GO:0098655 238 0.017
somitogenesis GO:0001756 2 0.017
response to oxygen levels GO:0070482 100 0.017
forebrain generation of neurons GO:0021872 3 0.017
leukocyte chemotaxis GO:0030595 76 0.017
immune response GO:0006955 307 0.017
negative regulation of protein kinase activity GO:0006469 98 0.017
peptidyl lysine acetylation GO:0018394 101 0.017
response to organonitrogen compound GO:0010243 156 0.017
tissue morphogenesis GO:0048729 96 0.017
Fly
positive regulation of cell differentiation GO:0045597 211 0.017
cellular ion homeostasis GO:0006873 168 0.017
blastoderm segmentation GO:0007350 2 0.017
cell chemotaxis GO:0060326 112 0.017
regulation of neuron differentiation GO:0045664 70 0.017
Fly
detection of stimulus GO:0051606 85 0.017
organelle fission GO:0048285 149 0.017
regulation of chromosome organization GO:0033044 103 0.016
regulation of response to wounding GO:1903034 101 0.016
metal ion homeostasis GO:0055065 169 0.016
metanephric nephron tubule morphogenesis GO:0072282 1 0.016
monovalent inorganic cation transport GO:0015672 128 0.016
oocyte differentiation GO:0009994 2 0.016
positive regulation of endothelial cell development GO:1901552 1 0.016
cellular cation homeostasis GO:0030003 163 0.016
inner ear morphogenesis GO:0042472 4 0.016
stress fiber assembly GO:0043149 40 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
Fly
regulation of epithelial cell proliferation GO:0050678 113 0.016
regulation of binding GO:0051098 111 0.016
anatomical structure homeostasis GO:0060249 100 0.015
ectoderm development GO:0007398 3 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
regulation of lymphocyte activation GO:0051249 103 0.015
gastrulation GO:0007369 51 0.015
Fly
hematopoietic or lymphoid organ development GO:0048534 186 0.015
hemopoiesis GO:0030097 180 0.015
lipid localization GO:0010876 106 0.015
nuclear division GO:0000280 128 0.015
regulation of secretion GO:0051046 194 0.015
heart induction GO:0003129 4 0.015
regulation of cell cell adhesion GO:0022407 57 0.015
cannabinoid signaling pathway GO:0038171 2 0.015
regulation of synaptic plasticity GO:0048167 3 0.015
response to decreased oxygen levels GO:0036293 96 0.015
positive regulation of immune system process GO:0002684 283 0.014
regulation of cell growth GO:0001558 135 0.014
response to oxidative stress GO:0006979 121 0.014
negative regulation of cardioblast differentiation GO:0051892 2 0.014
head development GO:0060322 108 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
tor signaling GO:0031929 39 0.014
negative regulation of cell development GO:0010721 48 0.014
lymphocyte activation GO:0046649 133 0.014
lipid transport GO:0006869 90 0.014
regulation of cell division GO:0051302 116 0.014
establishment of tissue polarity GO:0007164 3 0.014
neuron fate commitment GO:0048663 2 0.014
glycerolipid metabolic process GO:0046486 107 0.014
neural tube formation GO:0001841 3 0.014
regulation of cell activation GO:0050865 125 0.014
cranial nerve development GO:0021545 4 0.014
negative regulation of protein maturation GO:1903318 142 0.014
epidermis morphogenesis GO:0048730 3 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
compound eye development GO:0048749 1 0.014
developmental growth involved in morphogenesis GO:0060560 23 0.014
Fly
phospholipid metabolic process GO:0006644 99 0.014
regulation of protein transport GO:0051223 213 0.014
leukocyte migration GO:0050900 107 0.014
long term memory GO:0007616 2 0.014
cell cell adhesion mediated by cadherin GO:0044331 4 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
negative regulation of organelle organization GO:0010639 126 0.014
alpha amino acid metabolic process GO:1901605 72 0.014
negative regulation of phosphatase activity GO:0010923 61 0.014
regulation of stem cell differentiation GO:2000736 56 0.014
positive regulation of transport GO:0051050 336 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.014
organelle assembly GO:0070925 176 0.014
regulation of phosphatase activity GO:0010921 81 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
endodermal cell fate specification GO:0001714 4 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
positive regulation of organelle organization GO:0010638 195 0.013
innate immune response GO:0045087 178 0.013
cochlea development GO:0090102 1 0.013
epithelial cell proliferation GO:0050673 128 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
single organism behavior GO:0044708 28 0.013
Worm
wound healing GO:0042060 115 0.013
regulation of immune response GO:0050776 201 0.013
gastrulation with mouth forming second GO:0001702 1 0.013
single organismal cell cell adhesion GO:0016337 148 0.013
cellular chemical homeostasis GO:0055082 180 0.013
positive regulation of rab gtpase activity GO:0032851 39 0.013
golgi vesicle transport GO:0048193 80 0.013
stem cell development GO:0048864 69 0.013
vasculature development GO:0001944 181 0.013
cellular modified amino acid metabolic process GO:0006575 64 0.013
protein ubiquitination GO:0016567 314 0.013
thymus development GO:0048538 3 0.013
cellular calcium ion homeostasis GO:0006874 117 0.013
neurogenesis GO:0022008 169 0.013
Fly
peripheral nervous system development GO:0007422 2 0.013
cell fate commitment involved in pattern specification GO:0060581 1 0.013
positive regulation of mitotic cell cycle GO:0045931 60 0.013
detection of stimulus involved in sensory perception GO:0050906 43 0.013
pancreatic a cell differentiation GO:0003310 1 0.012
spermatid development GO:0007286 4 0.012
protein maturation GO:0051604 233 0.012
positive regulation of cell death GO:0010942 263 0.012
developmental process involved in reproduction GO:0003006 66 0.012
Fly
stem cell differentiation GO:0048863 93 0.012
protein targeting GO:0006605 187 0.012
positive regulation of cell division GO:0051781 59 0.012
cell activation GO:0001775 213 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
response to light stimulus GO:0009416 87 0.012
sensory perception of sound GO:0007605 37 0.012
calcium ion homeostasis GO:0055074 122 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
negative regulation of immune system process GO:0002683 136 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
response to hypoxia GO:0001666 96 0.012
negative regulation of growth GO:0045926 97 0.012
sleep GO:0030431 2 0.012
organophosphate biosynthetic process GO:0090407 163 0.012

ARHGEF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.101
hypersensitivity reaction disease DOID:0060056 25 0.039
disease of metabolism DOID:0014667 295 0.028
cancer DOID:162 167 0.026
Human
disease of cellular proliferation DOID:14566 174 0.026
Human
organ system cancer DOID:0050686 164 0.026
Human
inherited metabolic disorder DOID:655 242 0.017
musculoskeletal system disease DOID:17 223 0.015
sensory system disease DOID:0050155 203 0.012
nervous system disease DOID:863 431 0.012