Homo sapiens

97 known processes

CENPF

centromere protein F, 350/400kDa (mitosin)

(Aliases: PRO1779,CENF,hcp-1)

CENPF biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome segregation GO:0007059 114 0.714
nuclear division GO:0000280 128 0.682
Worm
microtubule based process GO:0007017 210 0.626
Worm
microtubule polymerization or depolymerization GO:0031109 37 0.616
organelle fission GO:0048285 149 0.613
Worm
neuroblast proliferation GO:0007405 4 0.545
microtubule cytoskeleton organization GO:0000226 176 0.535
Worm
nucleoside triphosphate metabolic process GO:0009141 422 0.455
spindle assembly involved in mitosis GO:0090307 12 0.438
cellular protein complex assembly GO:0043623 188 0.424
Worm
mitotic cell cycle GO:0000278 326 0.415
organelle assembly GO:0070925 176 0.403
Worm
meiotic chromosome segregation GO:0045132 4 0.384
mitotic cell cycle process GO:1903047 286 0.382
ribonucleoside triphosphate catabolic process GO:0009203 391 0.375
microtubule anchoring GO:0034453 24 0.366
Worm
single organism cellular localization GO:1902580 332 0.362
sister chromatid segregation GO:0000819 54 0.356
Worm
microtubule organizing center organization GO:0031023 62 0.348
regulation of microtubule cytoskeleton organization GO:0070507 61 0.331
cellular macromolecular complex assembly GO:0034622 324 0.319
Worm
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.317
neuronal stem cell division GO:0036445 1 0.317
ribonucleoside catabolic process GO:0042454 406 0.306
establishment of spindle localization GO:0051293 12 0.304
mitotic nuclear division GO:0007067 119 0.303
Worm
nucleoside triphosphate catabolic process GO:0009143 394 0.300
embryo development GO:0009790 123 0.290
Worm
positive regulation of cell division GO:0051781 59 0.286
centrosome organization GO:0051297 58 0.285
regulation of cytoskeleton organization GO:0051493 177 0.281
glycosyl compound catabolic process GO:1901658 413 0.275
negative regulation of cellular component organization GO:0051129 235 0.273
neuroblast division GO:0055057 1 0.269
cell division GO:0051301 168 0.249
establishment of organelle localization GO:0051656 59 0.243
regulation of chromosome segregation GO:0051983 44 0.233
regulation of cell cycle process GO:0010564 266 0.226
regulation of protein localization GO:0032880 296 0.224
stem cell division GO:0017145 2 0.214
maintenance of location in cell GO:0051651 62 0.212
Worm
mitotic spindle elongation GO:0000022 4 0.209
ribonucleotide catabolic process GO:0009261 405 0.203
organelle localization GO:0051640 84 0.198
mitotic sister chromatid segregation GO:0000070 53 0.196
Worm
cellular component disassembly GO:0022411 92 0.194
post embryonic development GO:0009791 2 0.192
nucleoside phosphate catabolic process GO:1901292 412 0.181
cytoplasmic transport GO:0016482 379 0.179
regulation of microtubule based process GO:0032886 74 0.165
intracellular protein transport GO:0006886 270 0.161
purine ribonucleoside catabolic process GO:0046130 398 0.160
protein localization to organelle GO:0033365 280 0.158
nucleoside monophosphate catabolic process GO:0009125 159 0.155
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.153
positive regulation of cell cycle GO:0045787 140 0.152
nuclear transport GO:0051169 179 0.152
ribonucleoside triphosphate metabolic process GO:0009199 412 0.148
nucleus localization GO:0051647 1 0.145
purine containing compound catabolic process GO:0072523 411 0.145
protein targeting GO:0006605 187 0.144
purine nucleoside monophosphate metabolic process GO:0009126 186 0.142
spindle elongation GO:0051231 4 0.139
organophosphate catabolic process GO:0046434 430 0.136
purine nucleotide catabolic process GO:0006195 405 0.136
protein import GO:0017038 130 0.130
negative regulation of integrin activation GO:0033624 2 0.126
regulation of cell division GO:0051302 116 0.118
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.117
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.116
positive regulation of catabolic process GO:0009896 310 0.113
purine nucleoside triphosphate metabolic process GO:0009144 412 0.112
maintenance of protein location in cell GO:0032507 56 0.112
Worm
purine nucleoside triphosphate catabolic process GO:0009146 392 0.111
protein depolymerization GO:0051261 30 0.108
metaphase plate congression GO:0051310 18 0.107
nucleocytoplasmic transport GO:0006913 176 0.106
spindle assembly GO:0051225 29 0.105
nucleoside monophosphate metabolic process GO:0009123 191 0.104
proteasomal protein catabolic process GO:0010498 176 0.103
centrosome cycle GO:0007098 32 0.103
establishment of nucleus localization GO:0040023 1 0.102
positive regulation of cell cycle process GO:0090068 106 0.098
atp metabolic process GO:0046034 176 0.097
establishment of protein localization to organelle GO:0072594 172 0.094
somatic stem cell division GO:0048103 1 0.092
nucleotide catabolic process GO:0009166 408 0.092
purine ribonucleoside metabolic process GO:0046128 437 0.091
ribonucleoside monophosphate catabolic process GO:0009158 158 0.091
microtubule based movement GO:0007018 32 0.091
regulation of mitotic cell cycle GO:0007346 189 0.091
regulation of cell cycle GO:0051726 393 0.089
oogenesis GO:0048477 2 0.089
positive regulation of organelle organization GO:0010638 195 0.087
ribonucleoside monophosphate metabolic process GO:0009161 187 0.087
nucleoside catabolic process GO:0009164 408 0.086
spindle organization GO:0007051 53 0.084
Worm
mesenchyme development GO:0060485 59 0.082
regulation of establishment of protein localization GO:0070201 242 0.082
actin cytoskeleton organization GO:0030036 207 0.081
purine ribonucleotide catabolic process GO:0009154 404 0.080
blastocyst development GO:0001824 3 0.080
meiotic nuclear division GO:0007126 10 0.078
dna conformation change GO:0071103 113 0.076
atp catabolic process GO:0006200 157 0.074
nuclear migration GO:0007097 1 0.074
regulation of mitotic sister chromatid segregation GO:0033047 27 0.074
cellular macromolecule catabolic process GO:0044265 380 0.070
regulation of spindle organization GO:0090224 10 0.070
purine nucleoside catabolic process GO:0006152 398 0.069
actin filament based process GO:0030029 224 0.068
regulation of locomotion GO:0040012 329 0.068
positive regulation of cellular component organization GO:0051130 376 0.068
ubiquitin dependent protein catabolic process GO:0006511 206 0.067
negative regulation of organelle organization GO:0010639 126 0.065
regulation of cellular component biogenesis GO:0044087 281 0.064
microtubule polymerization GO:0046785 18 0.063
negative regulation of cell cycle GO:0045786 193 0.063
mitotic spindle organization GO:0007052 27 0.063
Worm
protein targeting to nucleus GO:0044744 104 0.061
positive regulation of protein transport GO:0051222 135 0.060
neurogenesis GO:0022008 169 0.060
positive regulation of mitosis GO:0045840 25 0.058
positive regulation of cellular catabolic process GO:0031331 284 0.058
modification dependent protein catabolic process GO:0019941 209 0.058
maintenance of location GO:0051235 112 0.058
Worm
positive regulation of kinase activity GO:0033674 204 0.057
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.055
regulation of proteolysis GO:0030162 293 0.054
negative regulation of proteolysis GO:0045861 132 0.053
positive regulation of protein kinase activity GO:0045860 190 0.053
nervous system development GO:0007399 293 0.053
protein catabolic process GO:0030163 325 0.053
anatomical structure formation involved in morphogenesis GO:0048646 284 0.052
nitrogen compound transport GO:0071705 191 0.052
positive regulation of cytoskeleton organization GO:0051495 83 0.052
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.051
female gamete generation GO:0007292 2 0.050
nuclear import GO:0051170 106 0.049
regulation of canonical wnt signaling pathway GO:0060828 88 0.049
positive regulation of neural precursor cell proliferation GO:2000179 2 0.049
organ morphogenesis GO:0009887 147 0.048
sister chromatid biorientation GO:0031134 2 0.047
Worm
positive regulation of transport GO:0051050 336 0.047
meiotic cell cycle process GO:1903046 8 0.045
cytokinesis GO:0000910 96 0.045
positive regulation of phosphorylation GO:0042327 394 0.044
centrosome duplication GO:0051298 28 0.044
protein import into nucleus GO:0006606 104 0.044
regulation of cytoplasmic transport GO:1903649 149 0.043
negative regulation of protein maturation GO:1903318 142 0.043
positive regulation of protein phosphorylation GO:0001934 313 0.041
nuclear pore organization GO:0006999 10 0.041
reproductive process GO:0022414 106 0.041
single organism nuclear import GO:1902593 104 0.041
positive regulation of proteolysis GO:0045862 142 0.040
positive regulation of intracellular protein transport GO:0090316 76 0.040
regulation of protein processing GO:0070613 150 0.040
regulation of cell differentiation GO:0045595 393 0.040
maintenance of protein location GO:0045185 57 0.039
Worm
cellular response to endogenous stimulus GO:0071495 336 0.038
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.038
regulation of protein transport GO:0051223 213 0.038
protein complex disassembly GO:0043241 52 0.037
cellular protein complex disassembly GO:0043624 36 0.036
microtubule bundle formation GO:0001578 15 0.035
embryo development ending in birth or egg hatching GO:0009792 34 0.035
Worm
negative regulation of cell differentiation GO:0045596 171 0.034
protein maturation GO:0051604 233 0.034
dna packaging GO:0006323 77 0.033
cell cycle checkpoint GO:0000075 117 0.033
regulation of kinase activity GO:0043549 314 0.033
purine nucleoside monophosphate catabolic process GO:0009128 158 0.032
establishment of cell polarity GO:0030010 22 0.032
positive regulation of neuroblast proliferation GO:0002052 2 0.031
regulation of protein catabolic process GO:0042176 155 0.031
protein processing GO:0016485 226 0.031
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.031
regulation of neuron differentiation GO:0045664 70 0.030
regulation of intracellular transport GO:0032386 195 0.030
cilium morphogenesis GO:0060271 75 0.030
nucleus organization GO:0006997 28 0.029
mitotic spindle midzone assembly GO:0051256 4 0.029
endomembrane system organization GO:0010256 196 0.029
positive regulation of transferase activity GO:0051347 227 0.029
wnt signaling pathway GO:0016055 156 0.029
epithelium development GO:0060429 227 0.029
meiotic cell cycle GO:0051321 13 0.029
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.029
Worm
protein polymerization GO:0051258 71 0.028
mitotic centrosome separation GO:0007100 1 0.028
male meiosis GO:0007140 1 0.028
regulation of proteasomal protein catabolic process GO:0061136 87 0.027
regulation of gtp catabolic process GO:0033124 180 0.027
modification dependent macromolecule catabolic process GO:0043632 212 0.027
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.027
Worm
positive regulation of cdc42 gtpase activity GO:0043089 6 0.026
macromolecular complex disassembly GO:0032984 60 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
forebrain generation of neurons GO:0021872 3 0.026
regulation of nucleocytoplasmic transport GO:0046822 98 0.026
regulation of cell development GO:0060284 161 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.025
regulation of cell migration GO:0030334 289 0.025
protein localization to nucleus GO:0034504 136 0.025
regulation of protein complex assembly GO:0043254 147 0.025
cytoskeleton dependent cytokinesis GO:0061640 22 0.024
regulation of intracellular protein transport GO:0033157 123 0.024
centrosome separation GO:0051299 3 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
regulation of cytokinesis GO:0032465 45 0.023
regulation of cellular protein catabolic process GO:1903362 96 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.023
positive regulation of protein catabolic process GO:0045732 75 0.023
spindle checkpoint GO:0031577 26 0.023
spindle midzone assembly GO:0051255 4 0.023
positive regulation of wnt signaling pathway GO:0030177 54 0.022
regulation of cellular component movement GO:0051270 334 0.022
establishment of spindle orientation GO:0051294 9 0.022
regulation of protein maturation GO:1903317 150 0.022
positive regulation of nuclear division GO:0051785 27 0.022
mitotic sister chromatid separation GO:0051306 18 0.022
positive regulation of cytoplasmic transport GO:1903651 82 0.022
mitotic spindle checkpoint GO:0071174 18 0.021
cellular component morphogenesis GO:0032989 314 0.021
positive regulation of dna metabolic process GO:0051054 73 0.021
regulation of cell motility GO:2000145 299 0.021
positive regulation of chromosome organization GO:2001252 41 0.020
regulation of nuclear division GO:0051783 65 0.020
regulation of neurogenesis GO:0050767 82 0.020
regulation of protein import into nucleus GO:0042306 78 0.020
positive regulation of mitotic cell cycle GO:0045931 60 0.020
positive regulation of cytokinesis GO:0032467 29 0.020
reproduction GO:0000003 63 0.020
positive regulation of intracellular transport GO:0032388 104 0.020
regulation of transferase activity GO:0051338 355 0.020
cell part morphogenesis GO:0032990 137 0.020
positive regulation of cell proliferation GO:0008284 301 0.019
cell projection assembly GO:0030031 126 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
regulation of mitosis GO:0007088 63 0.019
primary neural tube formation GO:0014020 3 0.019
brain morphogenesis GO:0048854 1 0.018
cell morphogenesis GO:0000902 296 0.018
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.018
secretion GO:0046903 254 0.018
growth GO:0040007 202 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
microtubule nucleation GO:0007020 6 0.018
negative regulation of cell division GO:0051782 31 0.018
negative regulation of protein processing GO:0010955 142 0.017
generation of neurons GO:0048699 152 0.017
regulation of protein targeting GO:1903533 91 0.017
cellular amino acid metabolic process GO:0006520 116 0.017
ras protein signal transduction GO:0007265 73 0.017
single organism membrane organization GO:0044802 268 0.017
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
cellular ketone metabolic process GO:0042180 80 0.016
cell projection organization GO:0030030 252 0.016
regulation of protein localization to nucleus GO:1900180 85 0.016
attachment of spindle microtubules to kinetochore GO:0008608 17 0.016
Worm
positive regulation of attachment of spindle microtubules to kinetochore GO:0051987 2 0.016
stem cell development GO:0048864 69 0.016
cell adhesion GO:0007155 325 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
regeneration GO:0031099 4 0.016
small gtpase mediated signal transduction GO:0007264 78 0.015
response to abiotic stimulus GO:0009628 336 0.015
neural tube closure GO:0001843 3 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
protein dephosphorylation GO:0006470 81 0.015
head development GO:0060322 108 0.015
chromosome separation GO:0051304 23 0.015
neural crest cell development GO:0014032 3 0.015
regulation of sister chromatid segregation GO:0033045 27 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
response to nitrogen compound GO:1901698 184 0.015
multicellular organismal aging GO:0010259 3 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
cell development GO:0048468 328 0.015
regulation of cellular response to stress GO:0080135 244 0.014
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.014
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
vesicle mediated transport GO:0016192 371 0.014
tissue regeneration GO:0042246 3 0.014
establishment or maintenance of cell polarity GO:0007163 31 0.014
negative regulation of developmental process GO:0051093 247 0.014
regulation of mitotic spindle organization GO:0060236 6 0.014
regulation of nervous system development GO:0051960 88 0.013
reciprocal meiotic recombination GO:0007131 4 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
dephosphorylation GO:0016311 209 0.013
cytoskeleton dependent intracellular transport GO:0030705 21 0.013
central nervous system development GO:0007417 123 0.013
multi organism reproductive process GO:0044703 54 0.013
regulation of organelle assembly GO:1902115 40 0.013
cellular protein catabolic process GO:0044257 261 0.013
negative regulation of protein catabolic process GO:0042177 59 0.013
determination of adult lifespan GO:0008340 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
neural crest cell migration GO:0001755 2 0.013
positive regulation of cellular protein catabolic process GO:1903364 37 0.013
positive regulation of protein import into nucleus GO:0042307 46 0.013
multi organism cellular process GO:0044764 156 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
negative regulation of chromosome organization GO:2001251 48 0.012
response to hormone GO:0009725 175 0.012
single fertilization GO:0007338 11 0.012
regulation of mitotic sister chromatid separation GO:0010965 27 0.012
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.012
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.012
atrial septum primum morphogenesis GO:0003289 1 0.012
cardiovascular system development GO:0072358 262 0.012
actin filament organization GO:0007015 128 0.012
cilium assembly GO:0042384 63 0.012
single organism reproductive process GO:0044702 98 0.012
mitochondrial genome maintenance GO:0000002 8 0.012
morphogenesis of an epithelium GO:0002009 60 0.012
tube morphogenesis GO:0035239 95 0.012
canonical wnt signaling pathway GO:0060070 116 0.011
meiosis i GO:0007127 4 0.011
cell projection morphogenesis GO:0048858 129 0.011
cell substrate adhesion GO:0031589 132 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
regulation of protein kinase activity GO:0045859 289 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
regulation of gtpase activity GO:0043087 180 0.011
nuclear export GO:0051168 69 0.011
apoptotic signaling pathway GO:0097190 268 0.011
negative regulation of cell development GO:0010721 48 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
reciprocal dna recombination GO:0035825 4 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
negative regulation of catabolic process GO:0009895 104 0.011
epithelial cell differentiation GO:0030855 141 0.011
negative regulation of cell cycle process GO:0010948 121 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
tube development GO:0035295 125 0.010
mitotic cell cycle checkpoint GO:0007093 68 0.010
protein oligomerization GO:0051259 173 0.010
response to radiation GO:0009314 151 0.010
regulation of protein stability GO:0031647 87 0.010
regulation of peptidase activity GO:0052547 180 0.010

CENPF disease predictions

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 41 0.102
congenital nervous system abnormality DOID:2490 21 0.075
microcephaly DOID:10907 6 0.024
disease of cellular proliferation DOID:14566 174 0.017
immune system disease DOID:2914 155 0.015
anemia DOID:2355 55 0.010
hematopoietic system disease DOID:74 100 0.010