|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.699
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.664
|
Human Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.631
|
Human Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.624
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.601
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.588
|
Human Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.523
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.506
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.505
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.491
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.491
|
|
|
|
response to copper ion
|
GO:0046688 |
8 |
0.465
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.438
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.434
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.433
|
Human Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.416
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.395
|
Human Mouse |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.392
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.369
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.364
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.352
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.340
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.309
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.306
|
Zebrafish |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.301
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.284
|
Human Mouse |
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.281
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.270
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.258
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.245
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.240
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.240
|
Human Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.239
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.233
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.227
|
|
|
|
negative regulation of neurotrophin trk receptor signaling pathway
|
GO:0051387 |
2 |
0.216
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.216
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.206
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.204
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.199
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.195
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.189
|
Human Mouse |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.189
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.186
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.185
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.179
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.178
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.178
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.176
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.173
|
|
|
|
regulation of neurotrophin trk receptor signaling pathway
|
GO:0051386 |
2 |
0.170
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.169
|
Human Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.165
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.162
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.161
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.158
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.157
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.155
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.154
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.152
|
Human |
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.151
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.148
|
Zebrafish Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.147
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.145
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.144
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.141
|
Human Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.134
|
Fly |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.133
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.133
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.133
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.132
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.130
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.129
|
Human Mouse |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.128
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.128
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.128
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.125
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.123
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.118
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.118
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.114
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.112
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.112
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.112
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.112
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.107
|
|
|
|
lung growth
|
GO:0060437 |
2 |
0.107
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.106
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.103
|
Zebrafish Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.102
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.100
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.100
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.099
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.099
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.098
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.096
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.096
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.094
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.092
|
Zebrafish |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.092
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.087
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.085
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.085
|
Zebrafish Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.084
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.083
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.083
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.083
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.083
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.082
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.081
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.081
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.077
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.076
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.076
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.076
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.076
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.075
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.075
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.073
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.072
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.072
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.071
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.069
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.069
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.068
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.067
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.066
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.065
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.065
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.065
|
Human |
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.064
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.064
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.062
|
Human Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.062
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.062
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.062
|
Zebrafish Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.061
|
Human |
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.061
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.061
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.061
|
Zebrafish Fly |
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.060
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.059
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.059
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.058
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.058
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.058
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.057
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.057
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.056
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.056
|
Human Mouse |
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.055
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.053
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.053
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.052
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.052
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.052
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.051
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.051
|
Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.051
|
Fly |
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.051
|
|
|
|
aging
|
GO:0007568 |
66 |
0.051
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.051
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.050
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.050
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.050
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.050
|
Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.050
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.049
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.049
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
8 |
0.049
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.049
|
|
|
|
negative regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040037 |
2 |
0.048
|
Zebrafish Fly |
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.048
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.047
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.047
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.047
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.047
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.045
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.045
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.045
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.045
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.044
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.044
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.044
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.043
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.043
|
Zebrafish Fly |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.042
|
Human |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.042
|
Mouse |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.042
|
Fly |
|
|
response to drug
|
GO:0042493 |
81 |
0.042
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.042
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.042
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.042
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.041
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.041
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.041
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.041
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.041
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.041
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.040
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.039
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.039
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.039
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.039
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.039
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.039
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.038
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.038
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.038
|
|
|
|
regulation of lamellipodium morphogenesis
|
GO:2000392 |
4 |
0.038
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.038
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.038
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.038
|
|
|
|
enteric nervous system development
|
GO:0048484 |
1 |
0.038
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.037
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.037
|
|
|
|
ureter development
|
GO:0072189 |
3 |
0.037
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.036
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.035
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.035
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.035
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.035
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.035
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.035
|
Human Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.035
|
|
|
|
system process
|
GO:0003008 |
349 |
0.034
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.034
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.034
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.034
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.034
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.034
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.034
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.034
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.033
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.033
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.033
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.033
|
Zebrafish Fly |
|
|
glial cell migration
|
GO:0008347 |
4 |
0.033
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.032
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.032
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.032
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.032
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.032
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.032
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.031
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.031
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.031
|
Zebrafish |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.031
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.031
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.031
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.031
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.031
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.031
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.030
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.030
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.030
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.030
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.030
|
Zebrafish Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.030
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.030
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.029
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.029
|
Fly |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.029
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.029
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.029
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.029
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.029
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.029
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.029
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.028
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.028
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.028
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.028
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.028
|
Mouse |
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.027
|
Human |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.027
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.027
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.027
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.027
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.026
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.026
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.026
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.026
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.026
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.025
|
|
|
|
regulation of icosanoid secretion
|
GO:0032303 |
4 |
0.025
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.025
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.025
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.025
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.025
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.025
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.025
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.025
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.025
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.025
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.025
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.025
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.025
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.024
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.024
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.024
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.024
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.024
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.024
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.024
|
Zebrafish |
|
|
dendritic cell apoptotic process
|
GO:0097048 |
4 |
0.024
|
|
|
|
branch elongation of an epithelium
|
GO:0060602 |
3 |
0.024
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.024
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.024
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.024
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.024
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.024
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.024
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.024
|
Fly |
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.024
|
Zebrafish Fly |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.024
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.024
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.024
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.023
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.023
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.023
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.023
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.023
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.023
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.023
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.023
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.023
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.023
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.023
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.023
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.023
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.023
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.023
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.023
|
Human |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.022
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.022
|
|
|
|
growth
|
GO:0040007 |
202 |
0.022
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
4 |
0.022
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.022
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.022
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.022
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.022
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.022
|
Human |
|
|
renal system development
|
GO:0072001 |
63 |
0.022
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.022
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.022
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.022
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.022
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.021
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.021
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.021
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.021
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.021
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.021
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.021
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.021
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.021
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.021
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.021
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.021
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.021
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.021
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
3 |
0.020
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.020
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.020
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.020
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.020
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.020
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.020
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.020
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.020
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.020
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.020
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.020
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.020
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.020
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.020
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.020
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.020
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.020
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.020
|
Fly |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.019
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.019
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.019
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.019
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.019
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.019
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.019
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.019
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.019
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.019
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.019
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.019
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.019
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.019
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.019
|
Fly |
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.019
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.019
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.019
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.018
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.018
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.018
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.018
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.018
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.018
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.018
|
Fly |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.018
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.018
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.018
|
Mouse |
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.018
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.018
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
1 |
0.018
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.018
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.018
|
Fly |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.018
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.018
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.018
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.018
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.018
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.018
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.018
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.018
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.018
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.018
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.018
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.018
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.017
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.017
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.017
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.017
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.017
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.017
|
Zebrafish |
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.017
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.017
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.017
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.017
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.017
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.017
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.017
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.017
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.017
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.017
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.017
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.016
|
Zebrafish |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.016
|
|
|
|
serotonin secretion
|
GO:0001820 |
1 |
0.016
|
|
|
|
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling
|
GO:0060665 |
1 |
0.016
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.016
|
Zebrafish Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.016
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.016
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.016
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.016
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.016
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.016
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.016
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.016
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.016
|
Zebrafish Fly |
|
|
endoderm formation
|
GO:0001706 |
33 |
0.016
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.016
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.016
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.016
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.016
|
|
|
|
macrophage activation involved in immune response
|
GO:0002281 |
1 |
0.016
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.016
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.016
|
Fly |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.016
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.016
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.016
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.015
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.015
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.015
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.015
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.015
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.015
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.015
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.015
|
Human |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.015
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.015
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.015
|
|
