Homo sapiens

43 known processes

SEC63

SEC63 homolog (S. cerevisiae)

(Aliases: SEC63L,PRO2507,ERdj2)

SEC63 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 212 0.246
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.179
transmembrane transport GO:0055085 399 0.159
modification dependent protein catabolic process GO:0019941 209 0.117
protein catabolic process GO:0030163 325 0.112
cellular protein catabolic process GO:0044257 261 0.112
ubiquitin dependent protein catabolic process GO:0006511 206 0.101
ion transmembrane transport GO:0034220 338 0.099
response to endoplasmic reticulum stress GO:0034976 49 0.097
Zebrafish
protein localization to endoplasmic reticulum GO:0070972 19 0.081
carbohydrate derivative biosynthetic process GO:1901137 207 0.079
cellular macromolecule catabolic process GO:0044265 380 0.078
protein localization to membrane GO:0072657 160 0.074
metal ion transport GO:0030001 272 0.072
protein modification by small protein conjugation GO:0032446 342 0.071
cellular amino acid metabolic process GO:0006520 116 0.070
protein ubiquitination GO:0016567 314 0.069
glycoprotein metabolic process GO:0009100 110 0.062
cellular divalent inorganic cation homeostasis GO:0072503 128 0.060
maintenance of location GO:0051235 112 0.058
lipid localization GO:0010876 106 0.055
cellular homeostasis GO:0019725 196 0.055
divalent inorganic cation homeostasis GO:0072507 136 0.054
protein localization to organelle GO:0033365 280 0.053
carbohydrate metabolic process GO:0005975 207 0.051
purine nucleotide catabolic process GO:0006195 405 0.050
glycoprotein biosynthetic process GO:0009101 91 0.049
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.048
regulation of proteolysis GO:0030162 293 0.047
inorganic ion transmembrane transport GO:0098660 231 0.047
proteasomal protein catabolic process GO:0010498 176 0.042
ion homeostasis GO:0050801 230 0.041
apoptotic signaling pathway GO:0097190 268 0.041
regulation of cellular amine metabolic process GO:0033238 11 0.040
establishment of protein localization to membrane GO:0090150 121 0.040
embryonic epithelial tube formation GO:0001838 4 0.040
cation homeostasis GO:0055080 189 0.040
response to biotic stimulus GO:0009607 276 0.038
single organism cellular localization GO:1902580 332 0.038
chemical homeostasis GO:0048878 306 0.038
negative regulation of apoptotic process GO:0043066 316 0.038
cytoplasmic transport GO:0016482 379 0.037
determination of adult lifespan GO:0008340 2 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
nucleotide catabolic process GO:0009166 408 0.036
glycosyl compound catabolic process GO:1901658 413 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
post embryonic development GO:0009791 2 0.035
innate immune response GO:0045087 178 0.035
cellular metal ion homeostasis GO:0006875 146 0.034
ribonucleotide catabolic process GO:0009261 405 0.034
single organism membrane organization GO:0044802 268 0.033
negative regulation of protein modification process GO:0031400 200 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.033
cation transport GO:0006812 331 0.033
divalent inorganic cation transport GO:0072511 158 0.033
intracellular protein transport GO:0006886 270 0.032
vesicle mediated transport GO:0016192 371 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.031
system process GO:0003008 349 0.031
Zebrafish
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
negative regulation of phosphorus metabolic process GO:0010563 267 0.031
single organism carbohydrate metabolic process GO:0044723 193 0.031
immune response GO:0006955 307 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.030
cellular cation homeostasis GO:0030003 163 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
cellular amine metabolic process GO:0044106 41 0.029
positive regulation of immune system process GO:0002684 283 0.029
metal ion homeostasis GO:0055065 169 0.029
ribonucleoside triphosphate metabolic process GO:0009199 412 0.029
response to other organism GO:0051707 261 0.028
osteoblast differentiation GO:0001649 92 0.028
ribonucleoside catabolic process GO:0042454 406 0.027
regulation of locomotion GO:0040012 329 0.027
divalent metal ion transport GO:0070838 152 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
cellular lipid metabolic process GO:0044255 303 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.025
purine nucleoside catabolic process GO:0006152 398 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
amine metabolic process GO:0009308 44 0.024
cation transmembrane transport GO:0098655 238 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
macromolecule glycosylation GO:0043413 63 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
regulation of protein localization GO:0032880 296 0.022
protein targeting GO:0006605 187 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
regulation of protein ubiquitination GO:0031396 95 0.021
intrinsic apoptotic signaling pathway GO:0097193 127 0.021
sequestering of metal ion GO:0051238 24 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
cardiovascular system development GO:0072358 262 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
defense response GO:0006952 315 0.021
nitrogen compound transport GO:0071705 191 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
regulation of cellular component movement GO:0051270 334 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
cellular chemical homeostasis GO:0055082 180 0.020
tissue morphogenesis GO:0048729 96 0.020
nervous system development GO:0007399 293 0.020
Zebrafish
negative regulation of phosphate metabolic process GO:0045936 267 0.020
response to external biotic stimulus GO:0043207 261 0.019
regulation of transferase activity GO:0051338 355 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
inorganic cation transmembrane transport GO:0098662 194 0.019
nucleoside catabolic process GO:0009164 408 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.019
ossification GO:0001503 121 0.019
regulation of cell motility GO:2000145 299 0.018
glycosylation GO:0070085 71 0.018
ameboidal type cell migration GO:0001667 135 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
purine containing compound catabolic process GO:0072523 411 0.018
regulation of cellular ketone metabolic process GO:0010565 50 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
spermatid development GO:0007286 4 0.017
regulation of cell migration GO:0030334 289 0.017
protein glycosylation GO:0006486 62 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
multicellular organismal aging GO:0010259 3 0.017
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.017
cellular ion homeostasis GO:0006873 168 0.016
gtp catabolic process GO:0006184 237 0.016
regulation of kinase activity GO:0043549 314 0.016
positive regulation of catabolic process GO:0009896 310 0.016
regulation of gtpase activity GO:0043087 180 0.016
locomotory behavior GO:0007626 1 0.015
cellular response to lipid GO:0071396 127 0.015
transition metal ion transport GO:0000041 23 0.015
negative regulation of cell death GO:0060548 345 0.015
dephosphorylation GO:0016311 209 0.015
anion transport GO:0006820 161 0.015
spermatid differentiation GO:0048515 4 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
cellular ketone metabolic process GO:0042180 80 0.015
biological adhesion GO:0022610 331 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
nucleobase containing compound transport GO:0015931 51 0.015
positive regulation of developmental process GO:0051094 314 0.015
muscle cell fate commitment GO:0042693 4 0.015
regulation of homeostatic process GO:0032844 121 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
cell adhesion GO:0007155 325 0.014
cellular calcium ion homeostasis GO:0006874 117 0.014
endocytosis GO:0006897 159 0.014
oxidation reduction process GO:0055114 396 0.014
circulatory system development GO:0072359 262 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
response to oxygen containing compound GO:1901700 369 0.013
neuromuscular junction development GO:0007528 3 0.013
segmentation GO:0035282 4 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
mitotic cell cycle process GO:1903047 286 0.013
calcium ion transport GO:0006816 147 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.012
golgi vesicle transport GO:0048193 80 0.012
regulation of cell differentiation GO:0045595 393 0.012
regulation of protein kinase activity GO:0045859 289 0.012
atp metabolic process GO:0046034 176 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
neurogenesis GO:0022008 169 0.012
regulation of vasculature development GO:1901342 97 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
rna interference GO:0016246 4 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
response to fungus GO:0009620 4 0.012
membrane organization GO:0061024 292 0.011
endomembrane system organization GO:0010256 196 0.011
sequestering of calcium ion GO:0051208 17 0.011
translation GO:0006412 132 0.011
regulation of phosphatase activity GO:0010921 81 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
metencephalon development GO:0022037 2 0.011
receptor mediated endocytosis GO:0006898 84 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
single organism cell adhesion GO:0098602 179 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
calcium ion homeostasis GO:0055074 122 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
regulation of protein catabolic process GO:0042176 155 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
regulation of calcium ion transport GO:0051924 79 0.011
cellular component morphogenesis GO:0032989 314 0.011
cytosolic calcium ion homeostasis GO:0051480 89 0.011
cell morphogenesis GO:0000902 296 0.010
protein targeting to membrane GO:0006612 42 0.010
positive regulation of phosphorylation GO:0042327 394 0.010
regulation of immune response GO:0050776 201 0.010
dna repair GO:0006281 198 0.010
lipid metabolic process GO:0006629 381 0.010
positive regulation of cell motility GO:2000147 177 0.010
regulation of metal ion transport GO:0010959 120 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
response to abiotic stimulus GO:0009628 336 0.010

SEC63 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.029
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
organ system cancer DOID:0050686 164 0.016