Homo sapiens

75 known processes

GMNN

geminin, DNA replication inhibitor

(Aliases: RP3-369A17.3,Gem)

GMNN biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.606
determination of adult lifespan GO:0008340 2 0.450
regulation of cell cycle GO:0051726 393 0.315
regulation of dna metabolic process GO:0051052 153 0.282
regulation of mitotic cell cycle GO:0007346 189 0.278
Fly
regeneration GO:0031099 4 0.261
dna replication initiation GO:0006270 6 0.222
response to external biotic stimulus GO:0043207 261 0.202
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.172
cellular response to dna damage stimulus GO:0006974 379 0.169
dna repair GO:0006281 198 0.161
regulation of meiotic cell cycle GO:0051445 4 0.142
chromatin modification GO:0016568 298 0.141
reproductive structure development GO:0048608 55 0.133
meiosis i GO:0007127 4 0.132
cellular macromolecular complex assembly GO:0034622 324 0.110
neurogenesis GO:0022008 169 0.103
nervous system development GO:0007399 293 0.097
regulation of cell cycle phase transition GO:1901987 126 0.087
embryo development GO:0009790 123 0.087
Fly
regulation of proteolysis GO:0030162 293 0.086
dna dependent dna replication GO:0006261 44 0.084
oocyte maturation GO:0001556 1 0.084
positive regulation of dna metabolic process GO:0051054 73 0.083
microtubule based process GO:0007017 210 0.083
microtubule cytoskeleton organization GO:0000226 176 0.083
multicellular organismal aging GO:0010259 3 0.081
response to biotic stimulus GO:0009607 276 0.072
receptor mediated endocytosis GO:0006898 84 0.069
vesicle mediated transport GO:0016192 371 0.063
protein dna complex subunit organization GO:0071824 80 0.061
oogenesis GO:0048477 2 0.059
cellular amino acid metabolic process GO:0006520 116 0.058
positive regulation of programmed cell death GO:0043068 249 0.056
cell cycle phase transition GO:0044770 173 0.056
mitotic cell cycle phase transition GO:0044772 162 0.054
cytokinesis GO:0000910 96 0.054
response to other organism GO:0051707 261 0.053
response to organic cyclic compound GO:0014070 204 0.049
growth GO:0040007 202 0.049
sex differentiation GO:0007548 45 0.049
protein modification by small protein conjugation GO:0032446 342 0.048
response to abiotic stimulus GO:0009628 336 0.046
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 4 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.043
gonad development GO:0008406 34 0.043
reproductive process GO:0022414 106 0.042
negative regulation of protein modification process GO:0031400 200 0.042
protein acetylation GO:0006473 116 0.041
mitotic cell cycle GO:0000278 326 0.041
Fly
reproductive system development GO:0061458 56 0.039
regulation of cell cycle process GO:0010564 266 0.039
ras protein signal transduction GO:0007265 73 0.038
covalent chromatin modification GO:0016569 254 0.038
single organism reproductive process GO:0044702 98 0.037
response to lipid GO:0033993 206 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.036
positive regulation of cell proliferation GO:0008284 301 0.035
negative regulation of cell cycle GO:0045786 193 0.034
dna replication GO:0006260 116 0.034
positive regulation of apoptotic process GO:0043065 246 0.034
chromatin organization GO:0006325 351 0.034
positive regulation of cell death GO:0010942 263 0.034
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
cell part morphogenesis GO:0032990 137 0.033
Zebrafish
regulation of meiosis GO:0040020 3 0.033
cellular response to oxygen containing compound GO:1901701 276 0.032
small gtpase mediated signal transduction GO:0007264 78 0.032
cell morphogenesis GO:0000902 296 0.032
Zebrafish
female gamete generation GO:0007292 2 0.032
mitotic cell cycle process GO:1903047 286 0.031
positive regulation of developmental process GO:0051094 314 0.030
dna integrity checkpoint GO:0031570 71 0.030
negative regulation of catalytic activity GO:0043086 335 0.029
regulation of cellular response to stress GO:0080135 244 0.029
modification dependent macromolecule catabolic process GO:0043632 212 0.029
meiotic chromosome segregation GO:0045132 4 0.028
cellular ketone metabolic process GO:0042180 80 0.028
reproduction GO:0000003 63 0.027
Worm
response to steroid hormone GO:0048545 80 0.027
response to activity GO:0014823 0 0.027
organophosphate biosynthetic process GO:0090407 163 0.026
response to drug GO:0042493 81 0.026
cellular response to endogenous stimulus GO:0071495 336 0.026
tissue regeneration GO:0042246 3 0.026
posttranscriptional regulation of gene expression GO:0010608 213 0.026
wound healing GO:0042060 115 0.026
immune response GO:0006955 307 0.025
ubiquitin dependent protein catabolic process GO:0006511 206 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.025
internal protein amino acid acetylation GO:0006475 101 0.025
generation of neurons GO:0048699 152 0.025
microtubule organizing center organization GO:0031023 62 0.024
developmental process involved in reproduction GO:0003006 66 0.024
cell development GO:0048468 328 0.024
mitotic dna integrity checkpoint GO:0044774 30 0.023
organelle assembly GO:0070925 176 0.023
Zebrafish
regulation of cellular amine metabolic process GO:0033238 11 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
organonitrogen compound biosynthetic process GO:1901566 200 0.022
cellular protein catabolic process GO:0044257 261 0.021
response to ionizing radiation GO:0010212 65 0.021
cellular component assembly involved in morphogenesis GO:0010927 73 0.021
Zebrafish
protein maturation GO:0051604 233 0.021
endocytosis GO:0006897 159 0.021
negative regulation of organelle organization GO:0010639 126 0.020
regulation of mitotic cell cycle phase transition GO:1901990 118 0.020
embryo development ending in birth or egg hatching GO:0009792 34 0.020
negative regulation of cell cycle phase transition GO:1901988 89 0.020
response to oxidative stress GO:0006979 121 0.020
response to hormone GO:0009725 175 0.020
negative regulation of cell death GO:0060548 345 0.020
response to oxygen containing compound GO:1901700 369 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
cellular protein complex assembly GO:0043623 188 0.019
development of primary sexual characteristics GO:0045137 35 0.019
cell projection organization GO:0030030 252 0.019
Zebrafish
negative regulation of mitotic cell cycle GO:0045930 102 0.018
positive regulation of cell cycle GO:0045787 140 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
translesion synthesis GO:0019985 8 0.018
neuron development GO:0048666 113 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.018
cell division GO:0051301 168 0.018
regulation of cell differentiation GO:0045595 393 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.017
cellular component morphogenesis GO:0032989 314 0.017
Zebrafish
regulation of chromosome organization GO:0033044 103 0.017
circulatory system development GO:0072359 262 0.016
Zebrafish
developmental growth GO:0048589 48 0.016
protein ubiquitination GO:0016567 314 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
g1 s transition of mitotic cell cycle GO:0000082 78 0.015
protein acylation GO:0043543 138 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
regulation of cell division GO:0051302 116 0.015
peptidyl lysine acetylation GO:0018394 101 0.015
chromatin remodeling GO:0006338 55 0.015
regulation of response to dna damage stimulus GO:2001020 94 0.015
lipid metabolic process GO:0006629 381 0.015
positive regulation of dna replication GO:0045740 35 0.014
response to inorganic substance GO:0010035 127 0.014
cellular amine metabolic process GO:0044106 41 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
cell cycle checkpoint GO:0000075 117 0.014
dna conformation change GO:0071103 113 0.014
regulation of protein catabolic process GO:0042176 155 0.014
spindle organization GO:0007051 53 0.014
oxidation reduction process GO:0055114 396 0.014
blastocyst development GO:0001824 3 0.014
apoptotic signaling pathway GO:0097190 268 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
mitotic sister chromatid segregation GO:0000070 53 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.014
regulation of transferase activity GO:0051338 355 0.013
negative regulation of transferase activity GO:0051348 124 0.013
peptidyl threonine modification GO:0018210 45 0.013
biological adhesion GO:0022610 331 0.013
protein processing GO:0016485 226 0.012
asymmetric neuroblast division GO:0055059 1 0.012
dna recombination GO:0006310 77 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
asymmetric stem cell division GO:0098722 1 0.012
positive regulation of meiotic cell cycle GO:0051446 2 0.012
maintenance of location GO:0051235 112 0.012
regulation of protein kinase activity GO:0045859 289 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
peripheral nervous system development GO:0007422 2 0.012
histone serine phosphorylation GO:0035404 4 0.012
regulation of gene expression epigenetic GO:0040029 73 0.012
response to bacterium GO:0009617 144 0.012
cell cycle dna replication GO:0044786 11 0.012
chemical homeostasis GO:0048878 306 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
muscle cell differentiation GO:0042692 63 0.011
multicellular organism reproduction GO:0032504 42 0.011
response to oxygen levels GO:0070482 100 0.011
regulation of intracellular transport GO:0032386 195 0.011
hemopoiesis GO:0030097 180 0.011
behavior GO:0007610 112 0.011
rna interference GO:0016246 4 0.011
regulation of protein maturation GO:1903317 150 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
regulation of body fluid levels GO:0050878 99 0.011
response to decreased oxygen levels GO:0036293 96 0.011
negative regulation of meiotic cell cycle GO:0051447 2 0.011
regulation of kinase activity GO:0043549 314 0.011
histone modification GO:0016570 251 0.011
dna strand elongation involved in dna replication GO:0006271 3 0.011
amine metabolic process GO:0009308 44 0.010
regulation of cellular response to growth factor stimulus GO:0090287 76 0.010
histone acetylation GO:0016573 93 0.010
protein catabolic process GO:0030163 325 0.010
spermatid development GO:0007286 4 0.010
negative regulation of protein maturation GO:1903318 142 0.010

GMNN disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.264
inherited metabolic disorder DOID:655 242 0.264
carbohydrate metabolic disorder DOID:2978 55 0.062
disease of cellular proliferation DOID:14566 174 0.023