Homo sapiens

153 known processes

TREM2

triggering receptor expressed on myeloid cells 2

(Aliases: Trem2a,Trem2b,TREM-2,Trem2c)

TREM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic hydroxy compound transport GO:0015850 63 0.157
cytokine production GO:0001816 247 0.151
regulation of cellular component movement GO:0051270 334 0.150
positive regulation of cytokine production GO:0001819 167 0.150
cellular homeostasis GO:0019725 196 0.109
regulation of locomotion GO:0040012 329 0.103
cellular ketone metabolic process GO:0042180 80 0.100
cellular ion homeostasis GO:0006873 168 0.098
mapk cascade GO:0000165 288 0.097
regulation of mapk cascade GO:0043408 262 0.096
positive regulation of phosphorylation GO:0042327 394 0.094
cation homeostasis GO:0055080 189 0.093
ion homeostasis GO:0050801 230 0.093
vesicle mediated transport GO:0016192 371 0.088
g protein coupled receptor signaling pathway GO:0007186 207 0.087
positive regulation of transport GO:0051050 336 0.086
myeloid leukocyte migration GO:0097529 62 0.086
transmembrane transport GO:0055085 399 0.084
response to oxygen containing compound GO:1901700 369 0.084
lipid metabolic process GO:0006629 381 0.083
cellular amino acid metabolic process GO:0006520 116 0.083
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.082
negative regulation of cellular component organization GO:0051129 235 0.082
cell chemotaxis GO:0060326 112 0.082
cellular cation homeostasis GO:0030003 163 0.081
defense response GO:0006952 315 0.079
cellular lipid metabolic process GO:0044255 303 0.078
immune response GO:0006955 307 0.076
metal ion homeostasis GO:0055065 169 0.075
positive regulation of cellular amine metabolic process GO:0033240 7 0.074
cellular divalent inorganic cation homeostasis GO:0072503 128 0.074
divalent inorganic cation homeostasis GO:0072507 136 0.074
positive regulation of immune response GO:0050778 159 0.072
negative regulation of multicellular organismal process GO:0051241 317 0.070
chemical homeostasis GO:0048878 306 0.068
membrane organization GO:0061024 292 0.066
anion transport GO:0006820 161 0.064
signal transduction by phosphorylation GO:0023014 297 0.064
organic anion transport GO:0015711 103 0.063
regulation of response to external stimulus GO:0032101 222 0.062
response to organic cyclic compound GO:0014070 204 0.061
cation transport GO:0006812 331 0.061
response to wounding GO:0009611 168 0.060
response to biotic stimulus GO:0009607 276 0.060
lipid transport GO:0006869 90 0.060
regulation of transferase activity GO:0051338 355 0.060
cellular metal ion homeostasis GO:0006875 146 0.058
amine metabolic process GO:0009308 44 0.057
cellular calcium ion homeostasis GO:0006874 117 0.057
post embryonic development GO:0009791 2 0.057
positive regulation of hydrolase activity GO:0051345 331 0.056
negative regulation of platelet aggregation GO:0090331 3 0.056
lipid biosynthetic process GO:0008610 177 0.056
regulation of cellular amino acid metabolic process GO:0006521 6 0.055
regulation of plasma lipoprotein particle levels GO:0097006 32 0.054
regulation of cell motility GO:2000145 299 0.053
plasma lipoprotein particle clearance GO:0034381 16 0.053
negative regulation of cell motility GO:2000146 104 0.053
regulation of intracellular transport GO:0032386 195 0.052
response to other organism GO:0051707 261 0.051
positive regulation of protein phosphorylation GO:0001934 313 0.051
small gtpase mediated signal transduction GO:0007264 78 0.051
regulation of protein localization GO:0032880 296 0.050
regulation of cytokine production GO:0001817 232 0.049
ribonucleotide catabolic process GO:0009261 405 0.049
regulation of cellular ketone metabolic process GO:0010565 50 0.049
negative regulation of cellular component movement GO:0051271 106 0.048
nervous system development GO:0007399 293 0.048
negative regulation of phagocytosis GO:0050765 4 0.045
negative regulation of cell death GO:0060548 345 0.045
regulation of erk1 and erk2 cascade GO:0070372 99 0.045
positive regulation of kinase activity GO:0033674 204 0.045
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.044
response to external biotic stimulus GO:0043207 261 0.044
system process GO:0003008 349 0.044
regulation of nucleotide metabolic process GO:0006140 269 0.044
organophosphate catabolic process GO:0046434 430 0.044
response to cytokine GO:0034097 232 0.043
innate immune response GO:0045087 178 0.043
regulation of vesicle mediated transport GO:0060627 130 0.043
inflammatory response GO:0006954 79 0.043
regulation of immune response GO:0050776 201 0.043
carboxylic acid biosynthetic process GO:0046394 97 0.043
endocytosis GO:0006897 159 0.043
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.043
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.042
positive regulation of cellular component organization GO:0051130 376 0.041
ion transmembrane transport GO:0034220 338 0.041
regulation of macrophage chemotaxis GO:0010758 4 0.041
positive regulation of cell proliferation GO:0008284 301 0.040
small molecule biosynthetic process GO:0044283 157 0.040
female gamete generation GO:0007292 2 0.040
regulation of kinase activity GO:0043549 314 0.040
regulation of establishment of protein localization GO:0070201 242 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.040
secretion GO:0046903 254 0.039
divalent metal ion transport GO:0070838 152 0.039
biological adhesion GO:0022610 331 0.039
purine ribonucleoside catabolic process GO:0046130 398 0.039
cellular response to growth factor stimulus GO:0071363 197 0.039
positive regulation of transferase activity GO:0051347 227 0.039
positive regulation of developmental process GO:0051094 314 0.038
cell projection organization GO:0030030 252 0.038
epithelial cell proliferation GO:0050673 128 0.038
activation of immune response GO:0002253 114 0.038
single organism membrane organization GO:0044802 268 0.038
negative regulation of programmed cell death GO:0043069 321 0.038
response to growth factor GO:0070848 205 0.037
negative regulation of cell migration GO:0030336 102 0.037
purine ribonucleotide catabolic process GO:0009154 404 0.037
ras protein signal transduction GO:0007265 73 0.037
cellular response to cytokine stimulus GO:0071345 181 0.036
cellular amine metabolic process GO:0044106 41 0.036
single organism cellular localization GO:1902580 332 0.036
regulation of cell migration GO:0030334 289 0.036
regulation of protein kinase activity GO:0045859 289 0.036
cellular component morphogenesis GO:0032989 314 0.036
calcium ion homeostasis GO:0055074 122 0.036
positive regulation of mapk cascade GO:0043410 190 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.036
negative regulation of phosphorus metabolic process GO:0010563 267 0.035
regulation of cellular amine metabolic process GO:0033238 11 0.035
cell activation GO:0001775 213 0.035
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
glycerolipid metabolic process GO:0046486 107 0.035
regulation of cell activation GO:0050865 125 0.035
hemopoiesis GO:0030097 180 0.035
cadmium ion transport GO:0015691 2 0.034
cytosolic calcium ion homeostasis GO:0051480 89 0.034
regulation of cell differentiation GO:0045595 393 0.034
lipid localization GO:0010876 106 0.034
glycosyl compound catabolic process GO:1901658 413 0.034
rho protein signal transduction GO:0007266 26 0.033
positive regulation of immune system process GO:0002684 283 0.033
positive regulation of catabolic process GO:0009896 310 0.033
phospholipid metabolic process GO:0006644 99 0.033
positive regulation of nucleotide metabolic process GO:0045981 230 0.033
negative regulation of catalytic activity GO:0043086 335 0.033
determination of adult lifespan GO:0008340 2 0.033
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
organic acid biosynthetic process GO:0016053 97 0.033
gtp metabolic process GO:0046039 239 0.033
negative regulation of locomotion GO:0040013 118 0.033
negative regulation of immune system process GO:0002683 136 0.032
organic acid transport GO:0015849 65 0.032
positive regulation of epithelial cell proliferation GO:0050679 65 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
nucleotide catabolic process GO:0009166 408 0.032
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.032
sterol transport GO:0015918 39 0.032
regulation of protein transport GO:0051223 213 0.032
organophosphate biosynthetic process GO:0090407 163 0.032
multicellular organismal aging GO:0010259 3 0.032
regulation of cellular component biogenesis GO:0044087 281 0.032
cellular chemical homeostasis GO:0055082 180 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.031
postsynaptic membrane organization GO:0001941 2 0.031
enzyme linked receptor protein signaling pathway GO:0007167 303 0.031
i kappab kinase nf kappab signaling GO:0007249 166 0.031
cell morphogenesis GO:0000902 296 0.031
cytoplasmic transport GO:0016482 379 0.031
negative regulation of cell proliferation GO:0008285 228 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
peptidyl tyrosine modification GO:0018212 170 0.029
neuromuscular junction development GO:0007528 3 0.029
intracellular protein transport GO:0006886 270 0.029
negative regulation of macrophage differentiation GO:0045650 2 0.029
negative regulation of developmental process GO:0051093 247 0.029
organonitrogen compound biosynthetic process GO:1901566 200 0.029
regulation of ion transmembrane transport GO:0034765 132 0.029
taxis GO:0042330 157 0.029
regulation of renal albumin absorption GO:2000532 1 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
nucleoside triphosphate metabolic process GO:0009141 422 0.029
hematopoietic or lymphoid organ development GO:0048534 186 0.029
cholesterol transport GO:0030301 39 0.028
positive regulation of protein kinase activity GO:0045860 190 0.028
positive regulation of cell differentiation GO:0045597 211 0.028
single organism cell adhesion GO:0098602 179 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
monocarboxylic acid biosynthetic process GO:0072330 67 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.028
nucleoside phosphate biosynthetic process GO:1901293 109 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
oogenesis GO:0048477 2 0.027
ribonucleoside catabolic process GO:0042454 406 0.027
phagocytosis recognition GO:0006910 3 0.027
positive regulation of gtpase activity GO:0043547 166 0.027
oxidation reduction process GO:0055114 396 0.027
immune system development GO:0002520 195 0.027
blood coagulation GO:0007596 76 0.027
maintenance of location GO:0051235 112 0.027
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.026
regulation of synaptic plasticity GO:0048167 3 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.026
chemotaxis GO:0006935 157 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
locomotory behavior GO:0007626 1 0.026
guanosine containing compound catabolic process GO:1901069 239 0.026
response to nitrogen compound GO:1901698 184 0.026
regulation of cellular response to stress GO:0080135 244 0.026
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.025
leukocyte migration GO:0050900 107 0.025
nitrogen compound transport GO:0071705 191 0.025
gtp catabolic process GO:0006184 237 0.025
negative regulation of apoptotic process GO:0043066 316 0.025
single organismal cell cell adhesion GO:0016337 148 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
regulation of secretion GO:0051046 194 0.025
single organism carbohydrate metabolic process GO:0044723 193 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
cell type specific apoptotic process GO:0097285 125 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
granulocyte migration GO:0097530 40 0.024
second messenger mediated signaling GO:0019932 78 0.024
cellular response to endogenous stimulus GO:0071495 336 0.024
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
immune response activating signal transduction GO:0002757 90 0.024
protein localization to organelle GO:0033365 280 0.024
protein processing GO:0016485 226 0.024
dephosphorylation GO:0016311 209 0.023
secretion by cell GO:0032940 226 0.023
positive regulation of lipase activity GO:0060193 28 0.023
regulation of response to wounding GO:1903034 101 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
actin filament based process GO:0030029 224 0.023
carbohydrate metabolic process GO:0005975 207 0.023
regulation of leukocyte activation GO:0002694 115 0.023
protein oligomerization GO:0051259 173 0.023
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.023
wound healing GO:0042060 115 0.023
regulation of purine nucleotide catabolic process GO:0033121 205 0.023
exocytosis GO:0006887 71 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
response to abiotic stimulus GO:0009628 336 0.023
positive regulation of secretion GO:0051047 116 0.022
negative regulation of cell differentiation GO:0045596 171 0.022
response to lipid GO:0033993 206 0.022
fatty acid metabolic process GO:0006631 115 0.022
positive regulation of locomotion GO:0040017 186 0.022
positive regulation of keratinocyte migration GO:0051549 4 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
regulation of ion transport GO:0043269 189 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
purine containing compound catabolic process GO:0072523 411 0.022
cyclic nucleotide biosynthetic process GO:0009190 61 0.022
calcium ion transport GO:0006816 147 0.022
guanosine containing compound metabolic process GO:1901068 244 0.022
purine containing compound biosynthetic process GO:0072522 88 0.022
cytokine mediated signaling pathway GO:0019221 109 0.021
regulation of defense response GO:0031347 154 0.021
regulation of wound healing GO:0061041 56 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
memory GO:0007613 3 0.021
positive regulation of lipid metabolic process GO:0045834 50 0.021
neuron differentiation GO:0030182 138 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.021
peptidyl tyrosine phosphorylation GO:0018108 170 0.021
sensory perception GO:0007600 103 0.021
carbohydrate derivative biosynthetic process GO:1901137 207 0.021
regulation of proteolysis GO:0030162 293 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
circulatory system process GO:0003013 113 0.021
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.021
cell development GO:0048468 328 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.020
neurogenesis GO:0022008 169 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
nucleoside catabolic process GO:0009164 408 0.020
regulation of coagulation GO:0050818 44 0.020
divalent inorganic cation transport GO:0072511 158 0.020
metal ion transport GO:0030001 272 0.020
sequestering of metal ion GO:0051238 24 0.020
protein catabolic process GO:0030163 325 0.020
inorganic cation transmembrane transport GO:0098662 194 0.020
regulation of binding GO:0051098 111 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.020
regulation of cell adhesion GO:0030155 166 0.020
sensory perception of pain GO:0019233 4 0.020
leukocyte chemotaxis GO:0030595 76 0.020
mitotic cell cycle process GO:1903047 286 0.020
glial cell migration GO:0008347 4 0.020
positive regulation of cell death GO:0010942 263 0.019
regulation of reactive oxygen species metabolic process GO:2000377 41 0.019
regulation of secretion by cell GO:1903530 177 0.019
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
positive regulation of protein transport GO:0051222 135 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
endomembrane system organization GO:0010256 196 0.019
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.019
ribose phosphate biosynthetic process GO:0046390 82 0.019
camp metabolic process GO:0046058 61 0.019
regulation of nucleotide biosynthetic process GO:0030808 50 0.019
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 4 0.019
circulatory system development GO:0072359 262 0.019
humoral immune response GO:0006959 49 0.019
response to tumor necrosis factor GO:0034612 76 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
regeneration GO:0031099 4 0.019
response to oxidative stress GO:0006979 121 0.019
microtubule based process GO:0007017 210 0.019
positive regulation of cellular component biogenesis GO:0044089 158 0.019
positive regulation of organelle organization GO:0010638 195 0.019
generation of neurons GO:0048699 152 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.019
immune effector process GO:0002252 159 0.019
monocarboxylic acid metabolic process GO:0032787 185 0.019
positive regulation of chemotaxis GO:0050921 57 0.019
regulation of platelet aggregation GO:0090330 4 0.018
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.018
regulation of leukocyte differentiation GO:1902105 61 0.018
coagulation GO:0050817 78 0.018
regulation of small gtpase mediated signal transduction GO:0051056 156 0.018
negative regulation of homotypic cell cell adhesion GO:0034111 3 0.018
regulation of receptor mediated endocytosis GO:0048259 32 0.018
purine nucleotide biosynthetic process GO:0006164 84 0.018
blood circulation GO:0008015 113 0.018
response to fungus GO:0009620 4 0.018
erk1 and erk2 cascade GO:0070371 104 0.018
regulation of endocytosis GO:0030100 72 0.018
ameboidal type cell migration GO:0001667 135 0.018
cellular protein catabolic process GO:0044257 261 0.018
negative regulation of transport GO:0051051 176 0.018
neurological system process GO:0050877 163 0.018
protein localization to membrane GO:0072657 160 0.018
fatty acid biosynthetic process GO:0006633 46 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
actin cytoskeleton organization GO:0030036 207 0.018
negative regulation of response to external stimulus GO:0032102 83 0.018
response to bacterium GO:0009617 144 0.018
anatomical structure homeostasis GO:0060249 100 0.018
positive regulation of ion transport GO:0043270 87 0.018
regulation of homeostatic process GO:0032844 121 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
cell adhesion GO:0007155 325 0.018
neuron development GO:0048666 113 0.018
glucosamine containing compound catabolic process GO:1901072 3 0.018
cdc42 protein signal transduction GO:0032488 4 0.017
glycoprotein metabolic process GO:0009100 110 0.017
multicellular organismal homeostasis GO:0048871 67 0.017
regulation of epithelial cell proliferation GO:0050678 113 0.017
nucleotide biosynthetic process GO:0009165 109 0.017
oocyte development GO:0048599 1 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
luteolysis GO:0001554 3 0.017
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.017
negative regulation of response to cytokine stimulus GO:0060761 25 0.017
regulation of blood coagulation GO:0030193 42 0.017
regulation of cell projection organization GO:0031344 107 0.017
regulation of stress activated mapk cascade GO:0032872 84 0.017
tube morphogenesis GO:0035239 95 0.016
regulation of dna metabolic process GO:0051052 153 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
regulation of protein binding GO:0043393 66 0.016
negative regulation of synaptic transmission GO:0050805 2 0.016
stress activated mapk cascade GO:0051403 93 0.016
protein autophosphorylation GO:0046777 123 0.016
protein targeting GO:0006605 187 0.016
muscle system process GO:0003012 81 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.016
camp biosynthetic process GO:0006171 47 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.016
regulation of sterol transport GO:0032371 21 0.016
organ morphogenesis GO:0009887 147 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
regulation of chemotaxis GO:0050920 74 0.016
oocyte differentiation GO:0009994 2 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
positive regulation of cell motility GO:2000147 177 0.016
regulation of transmembrane transport GO:0034762 139 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
positive regulation of gtp catabolic process GO:0033126 166 0.016
negative regulation of protein modification process GO:0031400 200 0.016
cardiovascular system development GO:0072358 262 0.016
t cell activation GO:0042110 99 0.016
salivary gland morphogenesis GO:0007435 4 0.016
chemokine production GO:0032602 32 0.015
calcium mediated signaling GO:0019722 44 0.015
cyclic purine nucleotide metabolic process GO:0052652 60 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
negative regulation of blood pressure GO:0045776 3 0.015
cell cell signaling GO:0007267 155 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
response to nitric oxide GO:0071731 4 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
neural nucleus development GO:0048857 47 0.015
protein maturation GO:0051604 233 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
adult locomotory behavior GO:0008344 1 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
cholesterol efflux GO:0033344 28 0.015
positive regulation of cytoskeleton organization GO:0051495 83 0.015
regulation of inflammatory response GO:0050727 46 0.015
lipid catabolic process GO:0016042 84 0.015
regulation of cell cycle process GO:0010564 266 0.015
regulation of lipid metabolic process GO:0019216 96 0.015
neuron projection regeneration GO:0031102 1 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
regulation of hemostasis GO:1900046 42 0.015
regulation of intracellular protein transport GO:0033157 123 0.014
mast cell degranulation GO:0043303 4 0.014
segmentation GO:0035282 4 0.014
positive regulation of camp biosynthetic process GO:0030819 35 0.014
regulation of map kinase activity GO:0043405 108 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
leukocyte activation GO:0045321 164 0.014
negative regulation of cytokine production GO:0001818 82 0.014
organelle assembly GO:0070925 176 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
glycerophospholipid metabolic process GO:0006650 84 0.014
response to hormone GO:0009725 175 0.014
blastoderm segmentation GO:0007350 2 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
cell projection assembly GO:0030031 126 0.014
regulation of response to cytokine stimulus GO:0060759 46 0.014
immune response regulating signaling pathway GO:0002764 97 0.014
associative learning GO:0008306 1 0.014
apoptotic signaling pathway GO:0097190 268 0.014
negative regulation of kinase activity GO:0033673 106 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
neuron projection development GO:0031175 106 0.014
regulation of gtpase activity GO:0043087 180 0.014
response to axon injury GO:0048678 1 0.014
regulation of leukocyte chemotaxis GO:0002688 46 0.014
regulation of lymphocyte proliferation GO:0050670 64 0.014
regulation of actin filament based process GO:0032970 141 0.014
regulation of immune effector process GO:0002697 91 0.014
response to inorganic substance GO:0010035 127 0.014
serotonin transport GO:0006837 3 0.014
regulation of cellular response to growth factor stimulus GO:0090287 76 0.014
regulation of keratinocyte migration GO:0051547 4 0.014
actin filament organization GO:0007015 128 0.013
regulation of leukocyte migration GO:0002685 63 0.013
protein localization to plasma membrane GO:0072659 93 0.013
regulation of transmembrane transporter activity GO:0022898 74 0.013
hemostasis GO:0007599 76 0.013
cellular response to tumor necrosis factor GO:0071356 63 0.013
regulation of phagocytosis engulfment GO:0060099 2 0.013
response to virus GO:0009615 126 0.013
cellular protein complex assembly GO:0043623 188 0.013
myeloid leukocyte activation GO:0002274 34 0.013
purine ribonucleotide biosynthetic process GO:0009152 79 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of dephosphorylation GO:0035303 96 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
regulation of growth GO:0040008 165 0.013
interspecies interaction between organisms GO:0044419 156 0.013
visual learning GO:0008542 1 0.013
plasma membrane organization GO:0007009 115 0.013
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.013
carboxylic acid transport GO:0046942 63 0.013
regulation of multi organism process GO:0043900 157 0.013
negative regulation of response to wounding GO:1903035 47 0.013
stress activated protein kinase signaling cascade GO:0031098 94 0.013
regulation of protein complex assembly GO:0043254 147 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
spermatid differentiation GO:0048515 4 0.013
angiogenesis GO:0001525 147 0.013
positive regulation of aldosterone secretion GO:2000860 1 0.013
mononuclear cell proliferation GO:0032943 71 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
cell substrate adhesion GO:0031589 132 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
tube development GO:0035295 125 0.013

TREM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.073
inherited metabolic disorder DOID:655 242 0.073
central nervous system disease DOID:331 186 0.059
nervous system disease DOID:863 431 0.059
sensory system disease DOID:0050155 203 0.040
eye and adnexa disease DOID:1492 150 0.026
musculoskeletal system disease DOID:17 223 0.024
neurodegenerative disease DOID:1289 102 0.024
eye disease DOID:5614 149 0.022
disease of mental health DOID:150 70 0.022
connective tissue disease DOID:65 109 0.021
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.020
cardiovascular system disease DOID:1287 106 0.016
brain disease DOID:936 73 0.015
immune system disease DOID:2914 155 0.014
retinal disease DOID:5679 118 0.013
retinal degeneration DOID:8466 89 0.013