Homo sapiens

48 known processes

SMN1

survival of motor neuron 1, telomeric

(Aliases: SMA3,SMA2,SMA1,SMNT,SMN2,SMA4,BCD541,SMN,SMA@,T-BCD541,SMA)

SMN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spliceosomal snrnp assembly GO:0000387 28 1.000
ribonucleoprotein complex assembly GO:0022618 78 1.000
neutrophil clearance GO:0097350 1 1.000
oogenesis GO:0048477 2 1.000
Fly
ribonucleoprotein complex subunit organization GO:0071826 81 1.000
cellular response to glucocorticoid stimulus GO:0071385 4 1.000
female gamete generation GO:0007292 2 1.000
Fly
mapk cascade GO:0000165 288 1.000
negative regulation of interleukin 8 secretion GO:2000483 2 1.000
cytokinesis GO:0000910 96 0.999
rna splicing GO:0008380 131 0.999
regulation of vesicle fusion GO:0031338 5 0.999
mrna splicing via spliceosome GO:0000398 89 0.999
positive regulation of vesicle fusion GO:0031340 4 0.999
autophagic cell death GO:0048102 3 0.998
vesicle mediated transport GO:0016192 371 0.998
mrna processing GO:0006397 133 0.998
response to abiotic stimulus GO:0009628 336 0.998
negative regulation of protein secretion GO:0050709 29 0.998
cellular divalent inorganic cation homeostasis GO:0072503 128 0.997
cellular response to endogenous stimulus GO:0071495 336 0.997
neutrophil homeostasis GO:0001780 3 0.996
cellular response to growth factor stimulus GO:0071363 197 0.995
cellular metal ion homeostasis GO:0006875 146 0.994
rna splicing via transesterification reactions GO:0000375 90 0.992
regulation of protein transport GO:0051223 213 0.991
pathway restricted smad protein phosphorylation GO:0060389 38 0.990
ion homeostasis GO:0050801 230 0.990
response to growth factor GO:0070848 205 0.990
cellular response to lithium ion GO:0071285 2 0.990
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.988
cellular macromolecular complex assembly GO:0034622 324 0.987
cell division GO:0051301 168 0.986
Fly
water homeostasis GO:0030104 14 0.985
membrane organization GO:0061024 292 0.984
Fly
cation homeostasis GO:0055080 189 0.984
regulation of establishment of protein localization GO:0070201 242 0.981
zymogen activation GO:0031638 70 0.980
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.978
molting cycle GO:0042303 28 0.972
Worm
signal transduction by phosphorylation GO:0023014 297 0.971
calcium ion homeostasis GO:0055074 122 0.967
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.964
negative regulation of cytokine secretion GO:0050710 20 0.963
cellular calcium ion homeostasis GO:0006874 117 0.962
regulation of erk1 and erk2 cascade GO:0070372 99 0.957
response to lithium ion GO:0010226 2 0.946
neuron differentiation GO:0030182 138 0.946
ribonucleotide catabolic process GO:0009261 405 0.945
epithelial tube morphogenesis GO:0060562 38 0.944
regulation of endopeptidase activity GO:0052548 170 0.941
cellular chemical homeostasis GO:0055082 180 0.941
cellular ion homeostasis GO:0006873 168 0.924
positive regulation of phosphorylation GO:0042327 394 0.922
regulation of membrane potential GO:0042391 95 0.913
Fly
peptidyl serine modification GO:0018209 106 0.910
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.906
regulation of nucleotide catabolic process GO:0030811 205 0.906
regulation of cell cycle GO:0051726 393 0.904
Worm
positive regulation of protein kinase activity GO:0045860 190 0.903
histone acetylation GO:0016573 93 0.900
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.898
nucleoside triphosphate catabolic process GO:0009143 394 0.896
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.891
positive regulation of transferase activity GO:0051347 227 0.889
negative regulation of peptidase activity GO:0010466 91 0.887
single organism cellular localization GO:1902580 332 0.884
Fly
cell development GO:0048468 328 0.878
Worm Fly
regulation of protein localization GO:0032880 296 0.872
innate immune response GO:0045087 178 0.870
steroid metabolic process GO:0008202 94 0.869
interleukin 8 secretion GO:0072606 14 0.859
regulation of locomotion GO:0040012 329 0.846
positive regulation of protein phosphorylation GO:0001934 313 0.843
regulation of b cell proliferation GO:0030888 18 0.832
nucleoside monophosphate biosynthetic process GO:0009124 19 0.832
osteoclast development GO:0036035 2 0.832
nucleotide biosynthetic process GO:0009165 109 0.825
muscle structure development GO:0061061 98 0.818
Worm Fly
response to organic cyclic compound GO:0014070 204 0.805
response to salt stress GO:0009651 3 0.794
negative regulation of cell differentiation GO:0045596 171 0.793
ras protein signal transduction GO:0007265 73 0.789
immune response GO:0006955 307 0.765
generation of neurons GO:0048699 152 0.752
nuclear transport GO:0051169 179 0.747
regulation of protein secretion GO:0050708 86 0.744
positive regulation of nucleotide metabolic process GO:0045981 230 0.743
activation of cysteine type endopeptidase activity GO:0097202 57 0.743
positive regulation of hydrolase activity GO:0051345 331 0.742
positive regulation of nucleotide catabolic process GO:0030813 185 0.739
positive regulation of transport GO:0051050 336 0.736
regulation of cytoplasmic transport GO:1903649 149 0.721
regulation of peptidase activity GO:0052547 180 0.716
rna processing GO:0006396 255 0.712
negative regulation of cytokine production GO:0001818 82 0.702
nucleoside phosphate catabolic process GO:1901292 412 0.702
purine nucleotide catabolic process GO:0006195 405 0.693
regulation of epithelial cell migration GO:0010632 93 0.683
peptidyl lysine modification GO:0018205 144 0.681
divalent inorganic cation homeostasis GO:0072507 136 0.677
protein tetramerization GO:0051262 47 0.677
regulation of immune response GO:0050776 201 0.676
negative regulation of protein processing GO:0010955 142 0.672
mrna metabolic process GO:0016071 175 0.667
regulation of body fluid levels GO:0050878 99 0.663
metal ion homeostasis GO:0055065 169 0.644
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.637
Fly
nucleocytoplasmic transport GO:0006913 176 0.633
regulation of cell migration GO:0030334 289 0.631
regulation of wnt signaling pathway GO:0030111 123 0.631
regulation of cytokine production GO:0001817 232 0.630
regulation of cysteine type endopeptidase activity GO:2000116 127 0.628
regulation of interleukin 8 production GO:0032677 49 0.625
negative regulation of cellular component movement GO:0051271 106 0.624
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.622
regulation of cell motility GO:2000145 299 0.613
negative regulation of secretion by cell GO:1903531 52 0.612
ribonucleoside triphosphate catabolic process GO:0009203 391 0.596
positive regulation of cellular amine metabolic process GO:0033240 7 0.596
peptidyl serine phosphorylation GO:0018105 101 0.578
regulation of proteolysis GO:0030162 293 0.571
erk1 and erk2 cascade GO:0070371 104 0.565
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.553
protein oligomerization GO:0051259 173 0.552
negative regulation of secretion GO:0051048 58 0.552
internal peptidyl lysine acetylation GO:0018393 97 0.548
protein targeting GO:0006605 187 0.547
response to steroid hormone GO:0048545 80 0.542
calcium ion transport GO:0006816 147 0.542
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.538
positive regulation of endopeptidase activity GO:0010950 84 0.529
branching morphogenesis of an epithelial tube GO:0048754 19 0.521
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.516
positive regulation of cell death GO:0010942 263 0.504
autophagy GO:0006914 88 0.501
regulation of cellular component movement GO:0051270 334 0.501
cellular response to steroid hormone stimulus GO:0071383 37 0.494
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.481
receptor mediated endocytosis GO:0006898 84 0.479
regulation of innate immune response GO:0045088 97 0.453
cellular response to hormone stimulus GO:0032870 125 0.441
postsynaptic membrane organization GO:0001941 2 0.439
Fly
negative regulation of developmental process GO:0051093 247 0.428
nucleus organization GO:0006997 28 0.423
protein homotetramerization GO:0051289 28 0.408
regulation of meiotic cell cycle GO:0051445 4 0.404
Worm
negative regulation of interleukin 8 production GO:0032717 12 0.402
positive regulation of peptidase activity GO:0010952 88 0.395
positive regulation of organelle organization GO:0010638 195 0.382
membrane biogenesis GO:0044091 13 0.371
regulation of kinase activity GO:0043549 314 0.369
chemical homeostasis GO:0048878 306 0.367
regulation of cellular response to stress GO:0080135 244 0.367
negative regulation of transport GO:0051051 176 0.367
regulation of protein import into nucleus GO:0042306 78 0.364
regulation of purine nucleotide catabolic process GO:0033121 205 0.354
positive regulation of protein catabolic process GO:0045732 75 0.353
nervous system development GO:0007399 293 0.351
Fly
cell type specific apoptotic process GO:0097285 125 0.348
positive regulation of proteolysis GO:0045862 142 0.339
protein homooligomerization GO:0051260 100 0.334
mitotic cell cycle process GO:1903047 286 0.330
guanosine containing compound metabolic process GO:1901068 244 0.329
membrane raft assembly GO:0001765 7 0.321
positive regulation of mapk cascade GO:0043410 190 0.316
endocytosis GO:0006897 159 0.315
regulation of jnk cascade GO:0046328 73 0.312
cell cycle phase transition GO:0044770 173 0.309
regulation of cellular response to growth factor stimulus GO:0090287 76 0.309
enzyme linked receptor protein signaling pathway GO:0007167 303 0.306
peptide cross linking GO:0018149 12 0.306
regulation of mapk cascade GO:0043408 262 0.300
regulation of cell development GO:0060284 161 0.300
regulation of gtpase activity GO:0043087 180 0.299
nucleoside phosphate biosynthetic process GO:1901293 109 0.299
negative regulation of proteolysis GO:0045861 132 0.297
monovalent inorganic cation transport GO:0015672 128 0.294
regulation of mitotic cell cycle GO:0007346 189 0.289
Worm
neuromuscular junction development GO:0007528 3 0.283
Fly
protein maturation GO:0051604 233 0.278
protein localization to organelle GO:0033365 280 0.275
proteasomal protein catabolic process GO:0010498 176 0.272
negative regulation of transferase activity GO:0051348 124 0.263
anatomical structure homeostasis GO:0060249 100 0.263
heart development GO:0007507 95 0.260
cellular response to organonitrogen compound GO:0071417 124 0.253
negative regulation of neuron death GO:1901215 32 0.249
epithelium migration GO:0090132 119 0.248
protein import GO:0017038 130 0.248
synapse organization GO:0050808 14 0.243
Fly
activation of protein kinase activity GO:0032147 90 0.243
stem cell differentiation GO:0048863 93 0.232
Fly
protein modification by small protein conjugation GO:0032446 342 0.232
ribonucleoprotein complex biogenesis GO:0022613 116 0.232
regulation of protein localization to nucleus GO:1900180 85 0.230
cytoplasmic transport GO:0016482 379 0.229
amine metabolic process GO:0009308 44 0.227
negative regulation of protein metabolic process GO:0051248 391 0.224
cellular component morphogenesis GO:0032989 314 0.222
Worm Fly
purine ribonucleotide catabolic process GO:0009154 404 0.222
regulation of cellular amine metabolic process GO:0033238 11 0.210
purine nucleoside catabolic process GO:0006152 398 0.210
cytokine production GO:0001816 247 0.205
epithelial to mesenchymal transition GO:0001837 48 0.205
protein secretion GO:0009306 98 0.204
response to acid chemical GO:0001101 66 0.200
hemostasis GO:0007599 76 0.199
membrane depolarization GO:0051899 26 0.197
Fly
positive regulation of defense response GO:0031349 87 0.196
tissue migration GO:0090130 119 0.195
protein heterooligomerization GO:0051291 16 0.193
regulation of b cell activation GO:0050864 24 0.188
membrane assembly GO:0071709 10 0.182
cell volume homeostasis GO:0006884 3 0.181
negative regulation of cell proliferation GO:0008285 228 0.181
regulation of intracellular transport GO:0032386 195 0.176
negative regulation of protein transport GO:0051224 75 0.175
positive regulation of kinase activity GO:0033674 204 0.174
mitotic cell cycle phase transition GO:0044772 162 0.171
nuclear import GO:0051170 106 0.166
protein heterotetramerization GO:0051290 3 0.164
macromolecule methylation GO:0043414 97 0.162
positive regulation of b cell proliferation GO:0030890 12 0.161
response to inorganic substance GO:0010035 127 0.159
ribonucleoside monophosphate metabolic process GO:0009161 187 0.159
establishment of protein localization to organelle GO:0072594 172 0.158
posttranscriptional regulation of gene expression GO:0010608 213 0.156
protein processing GO:0016485 226 0.149
secretion by cell GO:0032940 226 0.140
steroid biosynthetic process GO:0006694 46 0.139
response to cytokine GO:0034097 232 0.138
endodermal cell differentiation GO:0035987 31 0.135
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.133
regulation of nucleocytoplasmic transport GO:0046822 98 0.131
synaptic transmission GO:0007268 61 0.131
Rat Fly
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.130
single organism membrane organization GO:0044802 268 0.128
Fly
regulation of cytokine secretion GO:0050707 57 0.127
positive regulation of programmed cell death GO:0043068 249 0.123
negative regulation of epithelial cell proliferation GO:0050680 48 0.121
rna modification GO:0009451 27 0.113
morphogenesis of a branching epithelium GO:0061138 20 0.111
deoxyribonucleoside monophosphate biosynthetic process GO:0009157 2 0.110
morphogenesis of an epithelium GO:0002009 60 0.110
modification by host of symbiont morphology or physiology GO:0051851 26 0.107
intracellular protein transport GO:0006886 270 0.107
lipid biosynthetic process GO:0008610 177 0.105
mesenchymal cell development GO:0014031 50 0.103
protein localization to nucleus GO:0034504 136 0.102
cell cycle g1 s phase transition GO:0044843 80 0.102
positive regulation of cell cycle GO:0045787 140 0.101
Worm
chromatin silencing at rdna GO:0000183 5 0.101
regulation of secretion by cell GO:1903530 177 0.101
developmental process involved in reproduction GO:0003006 66 0.097
Worm Fly
negative regulation of translation GO:0017148 37 0.096
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.090
regulation of cellular amino acid metabolic process GO:0006521 6 0.087
gtp catabolic process GO:0006184 237 0.086
negative regulation of epithelial to mesenchymal transition GO:0010719 14 0.086
regulation of mitotic cell cycle phase transition GO:1901990 118 0.085
segmentation GO:0035282 4 0.084
organophosphate biosynthetic process GO:0090407 163 0.084
cellular homeostasis GO:0019725 196 0.083
membrane budding GO:0006900 28 0.082
deoxyribonucleoside monophosphate metabolic process GO:0009162 3 0.079
regulation of chromatin modification GO:1903308 51 0.078
internal protein amino acid acetylation GO:0006475 101 0.077
response to other organism GO:0051707 261 0.076
anatomical structure formation involved in morphogenesis GO:0048646 284 0.073
Worm Fly
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.072
stem cell development GO:0048864 69 0.071
lipid metabolic process GO:0006629 381 0.070
regulation of protein catabolic process GO:0042176 155 0.070
regulation of translation GO:0006417 89 0.069
protein import into nucleus GO:0006606 104 0.068
protein import into nucleus translocation GO:0000060 22 0.068
regulation of intracellular protein transport GO:0033157 123 0.068
regulation of cell activation GO:0050865 125 0.067
protein catabolic process GO:0030163 325 0.066
positive regulation of catabolic process GO:0009896 310 0.064
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.063
activation of innate immune response GO:0002218 55 0.062
positive regulation of ion transport GO:0043270 87 0.062
skin development GO:0043588 76 0.060
purine nucleoside triphosphate metabolic process GO:0009144 412 0.058
translation GO:0006412 132 0.057
response to mechanical stimulus GO:0009612 51 0.057
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.057
central nervous system development GO:0007417 123 0.056
Fly
dna damage checkpoint GO:0000077 68 0.056
cellular ketone metabolic process GO:0042180 80 0.055
histone modification GO:0016570 251 0.054
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.053
regulation of protein targeting GO:1903533 91 0.053
positive regulation of apoptotic process GO:0043065 246 0.052
blood circulation GO:0008015 113 0.052
negative regulation of cell morphogenesis involved in differentiation GO:0010771 24 0.052
neuron apoptotic process GO:0051402 39 0.052
nucleoside monophosphate metabolic process GO:0009123 191 0.052
purine nucleoside triphosphate catabolic process GO:0009146 392 0.051
positive regulation of immune system process GO:0002684 283 0.050
gene silencing GO:0016458 49 0.049
negative regulation of multicellular organismal process GO:0051241 317 0.049
negative regulation of cell development GO:0010721 48 0.049
negative regulation of epithelial cell migration GO:0010633 38 0.048
formation of primary germ layer GO:0001704 42 0.048
regulation of defense response GO:0031347 154 0.048
post embryonic development GO:0009791 2 0.048
Worm Fly
wnt signaling pathway GO:0016055 156 0.047
platelet activation GO:0030168 44 0.046
cellular carbohydrate metabolic process GO:0044262 84 0.045
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.045
gtp metabolic process GO:0046039 239 0.045
positive regulation of cellular component movement GO:0051272 181 0.045
protein ubiquitination GO:0016567 314 0.043
cardiovascular system development GO:0072358 262 0.043
positive regulation of protein ubiquitination GO:0031398 53 0.042
cellular senescence GO:0090398 34 0.041
basement membrane organization GO:0071711 3 0.041
response to uv GO:0009411 73 0.040
reproductive structure development GO:0048608 55 0.040
system process GO:0003008 349 0.039
response to epidermal growth factor GO:0070849 14 0.039
negative regulation of growth GO:0045926 97 0.039
neurogenesis GO:0022008 169 0.038
protein modification by small protein removal GO:0070646 92 0.038
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.038
response to interferon gamma GO:0034341 39 0.037
positive regulation of intracellular transport GO:0032388 104 0.036
locomotory behavior GO:0007626 1 0.036
Fly
positive regulation of protein kinase b signaling GO:0051897 42 0.036
regulation of neuron differentiation GO:0045664 70 0.036
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.035
regulation of cell cycle process GO:0010564 266 0.035
tissue remodeling GO:0048771 16 0.034
negative regulation of cellular component organization GO:0051129 235 0.033
regulation of synaptic transmission dopaminergic GO:0032225 4 0.033
small gtpase mediated signal transduction GO:0007264 78 0.032
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.032
regulation of peptidyl serine phosphorylation GO:0033135 50 0.031
endoderm formation GO:0001706 33 0.031
defense response GO:0006952 315 0.030
regulation of homeostatic process GO:0032844 121 0.030
regulation of meiosis GO:0040020 3 0.030
response to organonitrogen compound GO:0010243 156 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.028
neuron death GO:0070997 65 0.028
positive regulation of ras gtpase activity GO:0032320 117 0.028
regulation of steroid biosynthetic process GO:0050810 23 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
negative regulation of locomotion GO:0040013 118 0.028
single organism nuclear import GO:1902593 104 0.027
post golgi vesicle mediated transport GO:0006892 36 0.027
positive regulation of protein transport GO:0051222 135 0.027
cytokine secretion GO:0050663 64 0.027
cellular potassium ion homeostasis GO:0030007 7 0.027
nucleoside catabolic process GO:0009164 408 0.027
intracellular receptor signaling pathway GO:0030522 104 0.027
mesenchymal cell differentiation GO:0048762 52 0.026
positive regulation of map kinase activity GO:0043406 80 0.026
regulation of protein ubiquitination GO:0031396 95 0.026
negative regulation of protein modification process GO:0031400 200 0.026
chromatin remodeling GO:0006338 55 0.025
regulation of androgen receptor signaling pathway GO:0060765 18 0.025
negative regulation of cell motility GO:2000146 104 0.025
regulation of lipid metabolic process GO:0019216 96 0.025
glycosyl compound catabolic process GO:1901658 413 0.025
protein targeting to nucleus GO:0044744 104 0.024
secretion GO:0046903 254 0.024
vasculature development GO:0001944 181 0.024
rna interference GO:0016246 4 0.024
neutral lipid metabolic process GO:0006638 27 0.023
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.023
homotypic cell cell adhesion GO:0034109 47 0.023
regulation of chromatin organization GO:1902275 56 0.023
negative regulation of innate immune response GO:0045824 18 0.023
response to molecule of bacterial origin GO:0002237 82 0.023
electron transport chain GO:0022900 8 0.023
cellular cation homeostasis GO:0030003 163 0.023
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.023
Worm Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.023
cellular macromolecule catabolic process GO:0044265 380 0.022
angiogenesis GO:0001525 147 0.022
calcium mediated signaling GO:0019722 44 0.022
telomere organization GO:0032200 33 0.022
negative regulation of immune response GO:0050777 40 0.022
positive regulation of dna metabolic process GO:0051054 73 0.022
cell projection morphogenesis GO:0048858 129 0.022
response to metal ion GO:0010038 84 0.022
epidermis development GO:0008544 59 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
regulation of steroid metabolic process GO:0019218 32 0.021
social behavior GO:0035176 14 0.020
purine containing compound catabolic process GO:0072523 411 0.020
spermatid differentiation GO:0048515 4 0.020
regulation of epithelial to mesenchymal transition GO:0010717 37 0.020
morphogenesis of a branching structure GO:0001763 21 0.020
regulation of ion transport GO:0043269 189 0.019
digestive tract development GO:0048565 75 0.018
myeloid leukocyte differentiation GO:0002573 60 0.018
protein stabilization GO:0050821 64 0.018
tissue morphogenesis GO:0048729 96 0.018
establishment of rna localization GO:0051236 39 0.018
regulation of vesicle mediated transport GO:0060627 130 0.018
tube morphogenesis GO:0035239 95 0.018
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.018
leukocyte mediated immunity GO:0002443 59 0.018
growth GO:0040007 202 0.018
jnk cascade GO:0007254 80 0.017
protein autophosphorylation GO:0046777 123 0.017
regulation of cell shape GO:0008360 48 0.017
negative regulation of exocytosis GO:0045920 6 0.017
positive regulation of cytoplasmic transport GO:1903651 82 0.017
nucleic acid transport GO:0050657 39 0.016
muscle cell proliferation GO:0033002 35 0.016
response to tumor necrosis factor GO:0034612 76 0.016
cellular response to nitrogen compound GO:1901699 144 0.016
nucleotide catabolic process GO:0009166 408 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
response to glucocorticoid GO:0051384 13 0.016
regulation of rna stability GO:0043487 23 0.016
neuron projection morphogenesis GO:0048812 50 0.016
maintenance of location GO:0051235 112 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
regulation of dna binding GO:0051101 37 0.016
response to external biotic stimulus GO:0043207 261 0.015
cellular amine metabolic process GO:0044106 41 0.015
regulation of lipid biosynthetic process GO:0046890 47 0.015
positive regulation of innate immune response GO:0045089 79 0.015
positive regulation of cell migration GO:0030335 172 0.015
sulfur compound metabolic process GO:0006790 101 0.015
chemotaxis GO:0006935 157 0.015
ribosome assembly GO:0042255 9 0.014
cellular sodium ion homeostasis GO:0006883 8 0.014
striated muscle contraction GO:0006941 52 0.014
positive regulation of lymphocyte activation GO:0051251 73 0.014
negative regulation of intracellular transport GO:0032387 60 0.014
regulation of anatomical structure size GO:0090066 101 0.014
positive regulation of synaptic transmission GO:0050806 4 0.014
Fly
single organism reproductive process GO:0044702 98 0.014
Worm Fly
regulation of nucleoside metabolic process GO:0009118 209 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
negative regulation of response to external stimulus GO:0032102 83 0.014
multicellular organismal homeostasis GO:0048871 67 0.014
developmental growth involved in morphogenesis GO:0060560 23 0.013
negative regulation of defense response GO:0031348 47 0.013
single organism membrane fusion GO:0044801 37 0.013
positive regulation of mitotic cell cycle spindle assembly checkpoint GO:0090267 6 0.013
regulation of secretion GO:0051046 194 0.013
response to radiation GO:0009314 151 0.013
regulation of calcium ion transport GO:0051924 79 0.013
pattern specification process GO:0007389 43 0.013
cytokine mediated signaling pathway GO:0019221 109 0.012
axon extension GO:0048675 13 0.012
negative regulation of cell cycle GO:0045786 193 0.012
Worm
cellular response to organic cyclic compound GO:0071407 127 0.012
lymphocyte activation GO:0046649 133 0.012
response to lipopolysaccharide GO:0032496 70 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
mature ribosome assembly GO:0042256 5 0.012
positive regulation of rho protein signal transduction GO:0035025 4 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
phagocytosis GO:0006909 42 0.011
mitotic cell cycle GO:0000278 326 0.011
Worm
vitamin d receptor signaling pathway GO:0070561 4 0.011
neurotransmitter gated ion channel clustering GO:0072578 1 0.011
Fly
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.011
positive regulation of cell cell adhesion GO:0022409 22 0.011
positive regulation of chromosome organization GO:2001252 41 0.011
regulation of dna replication GO:0006275 68 0.011
cellular response to external stimulus GO:0071496 111 0.011
embryo development GO:0009790 123 0.011
Worm Fly
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.011
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.011
multicellular organism reproduction GO:0032504 42 0.010
Worm Fly
posttranscriptional gene silencing GO:0016441 25 0.010
organ morphogenesis GO:0009887 147 0.010
positive regulation of secretion by cell GO:1903532 108 0.010
defense response to gram negative bacterium GO:0050829 14 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
response to x ray GO:0010165 8 0.010
regulation of protein maturation GO:1903317 150 0.010
regulation of protein processing GO:0070613 150 0.010

SMN1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.241
neurodegenerative disease DOID:1289 102 0.241
nervous system disease DOID:863 431 0.241
muscular disease DOID:0080000 114 0.142
musculoskeletal system disease DOID:17 223 0.142
muscle tissue disease DOID:66 113 0.076
myopathy DOID:423 104 0.065
motor neuron disease DOID:231 27 0.003
spinal muscular atrophy DOID:12377 3 0.002