Homo sapiens

60 known processes

MAT2A

methionine adenosyltransferase II, alpha

(Aliases: SAMS2,MATII,MATA2)

MAT2A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 41 0.134
amine metabolic process GO:0009308 44 0.111
cell development GO:0048468 328 0.098
Zebrafish
nucleoside catabolic process GO:0009164 408 0.096
negative regulation of epidermal cell differentiation GO:0045605 4 0.094
female gamete generation GO:0007292 2 0.079
cellular amino acid metabolic process GO:0006520 116 0.075
negative regulation of cell death GO:0060548 345 0.074
ras protein signal transduction GO:0007265 73 0.071
mitotic cell cycle process GO:1903047 286 0.070
regulation of anatomical structure morphogenesis GO:0022603 286 0.067
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 2 0.067
positive regulation of developmental process GO:0051094 314 0.063
Worm
locomotory behavior GO:0007626 1 0.062
chemical homeostasis GO:0048878 306 0.059
purine nucleoside triphosphate metabolic process GO:0009144 412 0.059
lipid metabolic process GO:0006629 381 0.058
Worm
negative regulation of hydrolase activity GO:0051346 182 0.058
reproductive process GO:0022414 106 0.056
Worm
regulation of cellular ketone metabolic process GO:0010565 50 0.056
epithelium development GO:0060429 227 0.054
determination of adult lifespan GO:0008340 2 0.053
Worm
epithelial cell proliferation involved in lung morphogenesis GO:0060502 3 0.052
purine containing compound catabolic process GO:0072523 411 0.051
purine ribonucleotide catabolic process GO:0009154 404 0.050
regulation of cellular amino acid metabolic process GO:0006521 6 0.050
protein alkylation GO:0008213 74 0.048
post embryonic development GO:0009791 2 0.046
Worm
negative regulation of protein metabolic process GO:0051248 391 0.046
carbohydrate derivative biosynthetic process GO:1901137 207 0.045
regulation of cellular amine metabolic process GO:0033238 11 0.045
cofactor metabolic process GO:0051186 87 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
purine nucleotide catabolic process GO:0006195 405 0.043
regulation of epithelial cell proliferation involved in lung morphogenesis GO:2000794 2 0.043
ribonucleoside catabolic process GO:0042454 406 0.042
transmembrane transport GO:0055085 399 0.042
multicellular organismal aging GO:0010259 3 0.042
Worm
negative regulation of catalytic activity GO:0043086 335 0.041
ribonucleoprotein complex biogenesis GO:0022613 116 0.041
regulation of cell differentiation GO:0045595 393 0.041
organonitrogen compound biosynthetic process GO:1901566 200 0.041
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.041
regulation of protein localization GO:0032880 296 0.040
negative regulation of cellular protein metabolic process GO:0032269 353 0.039
oxidation reduction process GO:0055114 396 0.038
purine ribonucleoside metabolic process GO:0046128 437 0.038
glycoprotein metabolic process GO:0009100 110 0.038
mrna splicing via spliceosome GO:0000398 89 0.038
negative regulation of endopeptidase activity GO:0010951 84 0.038
maintenance of location GO:0051235 112 0.037
Worm
ribonucleoside triphosphate metabolic process GO:0009199 412 0.037
cation homeostasis GO:0055080 189 0.037
adult locomotory behavior GO:0008344 1 0.036
regulation of growth rate GO:0040009 1 0.036
cation transport GO:0006812 331 0.036
response to biotic stimulus GO:0009607 276 0.036
anion transport GO:0006820 161 0.035
cellular homeostasis GO:0019725 196 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
nervous system development GO:0007399 293 0.034
cellular component morphogenesis GO:0032989 314 0.034
ion homeostasis GO:0050801 230 0.034
organophosphate catabolic process GO:0046434 430 0.034
cell projection organization GO:0030030 252 0.033
protein processing GO:0016485 226 0.033
regulation of response to wounding GO:1903034 101 0.033
memory GO:0007613 3 0.033
regulation of endopeptidase activity GO:0052548 170 0.033
cytokine production GO:0001816 247 0.033
growth GO:0040007 202 0.033
Worm
nucleoside triphosphate metabolic process GO:0009141 422 0.033
generation of neurons GO:0048699 152 0.033
small gtpase mediated signal transduction GO:0007264 78 0.032
carbohydrate metabolic process GO:0005975 207 0.032
response to oxygen containing compound GO:1901700 369 0.032
purine nucleoside catabolic process GO:0006152 398 0.032
response to other organism GO:0051707 261 0.032
response to external biotic stimulus GO:0043207 261 0.032
blastoderm segmentation GO:0007350 2 0.032
regulation of peptidase activity GO:0052547 180 0.031
positive regulation of hydrolase activity GO:0051345 331 0.031
mitotic nuclear division GO:0007067 119 0.031
regulation of meiotic cell cycle GO:0051445 4 0.031
regulation of establishment of protein localization GO:0070201 242 0.031
regeneration GO:0031099 4 0.030
rna splicing via transesterification reactions GO:0000375 90 0.030
nucleoside triphosphate catabolic process GO:0009143 394 0.030
cellular ketone metabolic process GO:0042180 80 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
purine nucleoside triphosphate catabolic process GO:0009146 392 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
rna processing GO:0006396 255 0.029
protein localization to membrane GO:0072657 160 0.028
hemopoiesis GO:0030097 180 0.028
negative regulation of epidermis development GO:0045683 5 0.028
regulation of proteolysis GO:0030162 293 0.028
neuron differentiation GO:0030182 138 0.027
cellular cation homeostasis GO:0030003 163 0.027
apoptotic signaling pathway GO:0097190 268 0.027
interspecies interaction between organisms GO:0044419 156 0.027
regulation of purine nucleotide catabolic process GO:0033121 205 0.027
regulation of rna splicing GO:0043484 62 0.027
organic anion transport GO:0015711 103 0.027
regulation of cell cycle GO:0051726 393 0.027
ncrna processing GO:0034470 83 0.027
cation transmembrane transport GO:0098655 238 0.026
ribonucleotide catabolic process GO:0009261 405 0.026
cell adhesion GO:0007155 325 0.026
negative regulation of keratinocyte differentiation GO:0045617 3 0.026
protein ubiquitination GO:0016567 314 0.026
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.026
myeloid cell differentiation GO:0030099 117 0.026
ncrna metabolic process GO:0034660 108 0.025
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.025
anterior posterior axis specification GO:0009948 2 0.025
system process GO:0003008 349 0.025
regulation of ras protein signal transduction GO:0046578 155 0.025
regulation of cysteine type endopeptidase activity GO:2000116 127 0.025
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.025
purine ribonucleoside catabolic process GO:0046130 398 0.024
nucleoside monophosphate metabolic process GO:0009123 191 0.024
cellular lipid metabolic process GO:0044255 303 0.024
cellular response to hormone stimulus GO:0032870 125 0.024
protein maturation GO:0051604 233 0.024
membrane organization GO:0061024 292 0.024
defense response GO:0006952 315 0.024
single organism reproductive process GO:0044702 98 0.024
Worm
cellular chemical homeostasis GO:0055082 180 0.024
establishment of protein localization to membrane GO:0090150 121 0.023
immune response GO:0006955 307 0.023
epithelial cell differentiation GO:0030855 141 0.023
cell morphogenesis GO:0000902 296 0.023
regulation of response to external stimulus GO:0032101 222 0.023
cellular response to oxygen containing compound GO:1901701 276 0.023
regulation of cell development GO:0060284 161 0.023
protein glycosylation GO:0006486 62 0.022
mrna metabolic process GO:0016071 175 0.022
positive regulation of cell death GO:0010942 263 0.022
positive regulation of immune system process GO:0002684 283 0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.022
cellular biogenic amine metabolic process GO:0006576 34 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
regulation of mitotic cell cycle GO:0007346 189 0.022
regulation of protein transport GO:0051223 213 0.022
compound eye development GO:0048749 1 0.022
regulation of cellular component biogenesis GO:0044087 281 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
tripartite regional subdivision GO:0007351 2 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.021
response to nitrogen compound GO:1901698 184 0.021
negative regulation of proteolysis GO:0045861 132 0.021
mitotic cell cycle GO:0000278 326 0.021
rna splicing GO:0008380 131 0.021
single organism membrane organization GO:0044802 268 0.021
regulation of growth GO:0040008 165 0.021
Worm
lipid biosynthetic process GO:0008610 177 0.021
polyamine metabolic process GO:0006595 4 0.021
regulation of anatomical structure size GO:0090066 101 0.021
protein homooligomerization GO:0051260 100 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
regulation of cell migration GO:0030334 289 0.021
negative regulation of programmed cell death GO:0043069 321 0.020
spermatid development GO:0007286 4 0.020
macromolecule glycosylation GO:0043413 63 0.020
protein oligomerization GO:0051259 173 0.020
metal ion homeostasis GO:0055065 169 0.020
response to virus GO:0009615 126 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.020
Worm
embryo development GO:0009790 123 0.020
Worm
cellular carbohydrate metabolic process GO:0044262 84 0.020
negative regulation of transport GO:0051051 176 0.020
cellular ion homeostasis GO:0006873 168 0.019
negative regulation of mrna metabolic process GO:1903312 15 0.019
biological adhesion GO:0022610 331 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.019
organ morphogenesis GO:0009887 147 0.019
negative regulation of peptidase activity GO:0010466 91 0.019
spermatid differentiation GO:0048515 4 0.019
protein localization to organelle GO:0033365 280 0.019
photoreceptor cell differentiation GO:0046530 2 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
nucleotide catabolic process GO:0009166 408 0.019
segmentation GO:0035282 4 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
tube development GO:0035295 125 0.018
female sex determination GO:0030237 1 0.018
lipid localization GO:0010876 106 0.018
Worm
regulation of meiosis GO:0040020 3 0.018
cellular response to endogenous stimulus GO:0071495 336 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
regulation of gene expression epigenetic GO:0040029 73 0.018
Worm
wound healing GO:0042060 115 0.018
multi organism cellular process GO:0044764 156 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
response to abiotic stimulus GO:0009628 336 0.018
spermidine metabolic process GO:0008216 3 0.018
glycoprotein biosynthetic process GO:0009101 91 0.018
response to wounding GO:0009611 168 0.018
chromatin organization GO:0006325 351 0.018
maturation of ssu rrna GO:0030490 3 0.018
regulation of wound healing GO:0061041 56 0.018
metal ion transport GO:0030001 272 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
regulation of protein maturation GO:1903317 150 0.017
regulation of cell growth GO:0001558 135 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
regulation of protein processing GO:0070613 150 0.017
positive regulation of organelle organization GO:0010638 195 0.017
negative regulation of epithelial cell differentiation GO:0030857 6 0.017
regulation of nervous system development GO:0051960 88 0.017
ion transmembrane transport GO:0034220 338 0.017
oogenesis GO:0048477 2 0.017
cellular modified amino acid metabolic process GO:0006575 64 0.017
cell activation GO:0001775 213 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
anterior posterior axis specification embryo GO:0008595 2 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.017
regulation of transferase activity GO:0051338 355 0.016
secretion GO:0046903 254 0.016
Worm
negative regulation of protein processing GO:0010955 142 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
mitochondrion organization GO:0007005 156 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
regulation of multi organism process GO:0043900 157 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
cellular biogenic amine biosynthetic process GO:0042401 4 0.016
regulation of mrna splicing via spliceosome GO:0048024 32 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
regulation of cell cycle process GO:0010564 266 0.016
cellular response to nitrogen compound GO:1901699 144 0.016
glycosyl compound catabolic process GO:1901658 413 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
glycosylation GO:0070085 71 0.015
negative regulation of protein maturation GO:1903318 142 0.015
neuron development GO:0048666 113 0.015
negative regulation of multi organism process GO:0043901 92 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
Worm
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
small molecule biosynthetic process GO:0044283 157 0.014
actin filament based process GO:0030029 224 0.014
protein catabolic process GO:0030163 325 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
negative regulation of protein modification process GO:0031400 200 0.014
actin cytoskeleton organization GO:0030036 207 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
neurological system process GO:0050877 163 0.014
regulation of epithelial cell proliferation GO:0050678 113 0.014
viral process GO:0016032 146 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
cellular component disassembly GO:0022411 92 0.014
limbic system development GO:0021761 3 0.014
negative regulation of catabolic process GO:0009895 104 0.014
response to hormone GO:0009725 175 0.014
epidermis development GO:0008544 59 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
negative regulation of mrna processing GO:0050686 12 0.014
response to organonitrogen compound GO:0010243 156 0.014
microtubule based process GO:0007017 210 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
regulation of mapk cascade GO:0043408 262 0.014
lipid transport GO:0006869 90 0.014
cell division GO:0051301 168 0.014
developmental programmed cell death GO:0010623 3 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
mating GO:0007618 1 0.013
alternative mrna splicing via spliceosome GO:0000380 27 0.013
cell growth GO:0016049 160 0.013
neurotransmitter secretion GO:0007269 4 0.013
maintenance of protein location GO:0045185 57 0.013
cell type specific apoptotic process GO:0097285 125 0.013
regulation of cytokine production GO:0001817 232 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
blood vessel development GO:0001568 172 0.013
negative regulation of cell growth GO:0030308 83 0.013
cellular response to lipid GO:0071396 127 0.013
gtp metabolic process GO:0046039 239 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
keratinocyte differentiation GO:0030216 36 0.013
regulation of cell division GO:0051302 116 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
viral life cycle GO:0019058 132 0.013
regulation of neuron differentiation GO:0045664 70 0.013
angiogenesis GO:0001525 147 0.013
ribosome biogenesis GO:0042254 48 0.013
response to bacterium GO:0009617 144 0.013
intracellular protein transport GO:0006886 270 0.012
epithelial cell proliferation GO:0050673 128 0.012
regulation of cellular response to stress GO:0080135 244 0.012
amine biosynthetic process GO:0009309 4 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.012
methylation GO:0032259 106 0.012
blood vessel morphogenesis GO:0048514 162 0.012
muscle contraction GO:0006936 73 0.012
coenzyme metabolic process GO:0006732 65 0.012
neuromuscular junction development GO:0007528 3 0.012
neural tube formation GO:0001841 3 0.012
phospholipid metabolic process GO:0006644 99 0.012
positive regulation of growth GO:0045927 58 0.012
Worm
neuron projection development GO:0031175 106 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
cell cycle phase transition GO:0044770 173 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
mapk cascade GO:0000165 288 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
positive regulation of dendrite morphogenesis GO:0050775 3 0.012
positive regulation of proteolysis GO:0045862 142 0.012
protein targeting GO:0006605 187 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
innate immune response GO:0045087 178 0.012
maintenance of protein location in cell GO:0032507 56 0.011
behavioral response to ethanol GO:0048149 2 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
immune effector process GO:0002252 159 0.011
negative regulation of rna splicing GO:0033119 15 0.011
regulation of epidermis development GO:0045682 19 0.011
lung alveolus development GO:0048286 4 0.011
skin development GO:0043588 76 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.011
regulation of homeostatic process GO:0032844 121 0.011
leukocyte activation GO:0045321 164 0.011
chromosome segregation GO:0007059 114 0.011
establishment of nucleus localization GO:0040023 1 0.011
protein methylation GO:0006479 74 0.011
organic acid biosynthetic process GO:0016053 97 0.011
regulation of secretion GO:0051046 194 0.011
lung morphogenesis GO:0060425 6 0.011
vasculature development GO:0001944 181 0.011
single organism cell adhesion GO:0098602 179 0.011
regulation of protein complex assembly GO:0043254 147 0.011
positive regulation of epithelial cell proliferation GO:0050679 65 0.011
atp metabolic process GO:0046034 176 0.011
striated muscle contraction GO:0006941 52 0.011
regulation of secretion by cell GO:1903530 177 0.011
response to molecule of bacterial origin GO:0002237 82 0.011
regulation of cellular component movement GO:0051270 334 0.011
glycerolipid metabolic process GO:0046486 107 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
regulation of protein targeting GO:1903533 91 0.011
reproduction GO:0000003 63 0.011
Worm
cardiovascular system development GO:0072358 262 0.011
Zebrafish
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
cell part morphogenesis GO:0032990 137 0.010
oocyte development GO:0048599 1 0.010
cytoplasmic transport GO:0016482 379 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
sensory perception GO:0007600 103 0.010
mitotic sister chromatid segregation GO:0000070 53 0.010
keratinocyte proliferation GO:0043616 17 0.010
regulation of mrna metabolic process GO:1903311 53 0.010
positive regulation of immune response GO:0050778 159 0.010
protein modification by small protein conjugation GO:0032446 342 0.010
multi organism reproductive process GO:0044703 54 0.010
negative regulation of developmental process GO:0051093 247 0.010
Worm
detection of stimulus GO:0051606 85 0.010
midgut development GO:0007494 1 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
divalent inorganic cation homeostasis GO:0072507 136 0.010
behavior GO:0007610 112 0.010
negative regulation of viral process GO:0048525 66 0.010
sister chromatid segregation GO:0000819 54 0.010
negative regulation of phosphorylation GO:0042326 174 0.010

MAT2A disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.050
nervous system disease DOID:863 431 0.050
musculoskeletal system disease DOID:17 223 0.046
myopathy DOID:423 104 0.035
muscular disease DOID:0080000 114 0.035
muscle tissue disease DOID:66 113 0.035
disease of mental health DOID:150 70 0.024
neurodegenerative disease DOID:1289 102 0.016
disease of cellular proliferation DOID:14566 174 0.014
muscular dystrophy DOID:9884 51 0.014
sensory system disease DOID:0050155 203 0.013
cancer DOID:162 167 0.012
organ system cancer DOID:0050686 164 0.012
immune system disease DOID:2914 155 0.011