Homo sapiens

193 known processes

AIM2

absent in melanoma 2

(Aliases: PYHIN4)

AIM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell activation GO:0001775 213 0.295
Human
response to biotic stimulus GO:0009607 276 0.237
Human
immune response GO:0006955 307 0.235
response to cytokine GO:0034097 232 0.223
positive regulation of immune system process GO:0002684 283 0.221
positive regulation of immune response GO:0050778 159 0.166
response to other organism GO:0051707 261 0.166
Human
defense response to virus GO:0051607 71 0.153
Human
activation of immune response GO:0002253 114 0.147
innate immune response GO:0045087 178 0.140
response to external biotic stimulus GO:0043207 261 0.131
Human
defense response GO:0006952 315 0.124
positive regulation of cellular component organization GO:0051130 376 0.122
regulation of establishment of protein localization GO:0070201 242 0.113
positive regulation of hydrolase activity GO:0051345 331 0.110
response to virus GO:0009615 126 0.109
Human
leukocyte activation GO:0045321 164 0.104
Human
cytoplasmic transport GO:0016482 379 0.099
defense response to other organism GO:0098542 129 0.098
Human
positive regulation of phosphorylation GO:0042327 394 0.095
secretion GO:0046903 254 0.090
cellular amino acid metabolic process GO:0006520 116 0.085
biological adhesion GO:0022610 331 0.084
regulation of multi organism process GO:0043900 157 0.081
Human
regulation of immune response GO:0050776 201 0.079
regulation of cell migration GO:0030334 289 0.079
positive regulation of cell death GO:0010942 263 0.079
Human
amine metabolic process GO:0009308 44 0.077
cytokine production GO:0001816 247 0.077
positive regulation of cell activation GO:0050867 81 0.077
positive regulation of mapk cascade GO:0043410 190 0.077
cellular ketone metabolic process GO:0042180 80 0.076
immune effector process GO:0002252 159 0.075
Human
response to bacterium GO:0009617 144 0.074
rho protein signal transduction GO:0007266 26 0.073
positive regulation of transport GO:0051050 336 0.073
cellular amine metabolic process GO:0044106 41 0.072
regulation of protein transport GO:0051223 213 0.070
cell adhesion GO:0007155 325 0.069
regulation of cellular amine metabolic process GO:0033238 11 0.068
regulation of peptidase activity GO:0052547 180 0.067
regulation of cellular amino acid metabolic process GO:0006521 6 0.066
regulation of defense response GO:0031347 154 0.065
regulation of cytokine production GO:0001817 232 0.065
regulation of leukocyte migration GO:0002685 63 0.065
regulation of cellular component movement GO:0051270 334 0.064
regulation of protein kinase activity GO:0045859 289 0.064
positive regulation of locomotion GO:0040017 186 0.063
interspecies interaction between organisms GO:0044419 156 0.062
Human
nucleoside catabolic process GO:0009164 408 0.062
response to abiotic stimulus GO:0009628 336 0.061
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.060
t cell activation GO:0042110 99 0.060
regulation of nucleotide metabolic process GO:0006140 269 0.060
small gtpase mediated signal transduction GO:0007264 78 0.059
cellular response to lipopolysaccharide GO:0071222 57 0.059
regulation of secretion GO:0051046 194 0.058
positive regulation of apoptotic process GO:0043065 246 0.058
Human
g protein coupled receptor signaling pathway GO:0007186 207 0.058
i kappab kinase nf kappab signaling GO:0007249 166 0.057
glycosyl compound catabolic process GO:1901658 413 0.056
lymphocyte activation GO:0046649 133 0.056
Human
immune system development GO:0002520 195 0.055
Human
signal transduction by phosphorylation GO:0023014 297 0.055
positive regulation of cell differentiation GO:0045597 211 0.055
protein secretion GO:0009306 98 0.053
response to oxygen containing compound GO:1901700 369 0.053
sequestering of calcium ion GO:0051208 17 0.052
regulation of cell motility GO:2000145 299 0.052
regulation of mapk cascade GO:0043408 262 0.051
secretion by cell GO:0032940 226 0.051
regulation of cellular component biogenesis GO:0044087 281 0.051
regulation of response to external stimulus GO:0032101 222 0.051
immune response activating signal transduction GO:0002757 90 0.051
Human
purine nucleoside catabolic process GO:0006152 398 0.050
cellular response to molecule of bacterial origin GO:0071219 62 0.050
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.050
purine ribonucleotide catabolic process GO:0009154 404 0.050
regulation of purine nucleotide metabolic process GO:1900542 264 0.049
regulation of viral process GO:0050792 103 0.048
Human
taxis GO:0042330 157 0.048
cellular response to oxygen containing compound GO:1901701 276 0.048
regulation of cell cycle GO:0051726 393 0.047
regulation of locomotion GO:0040012 329 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.047
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.047
Human
protein oligomerization GO:0051259 173 0.046
mapk cascade GO:0000165 288 0.045
negative regulation of cell proliferation GO:0008285 228 0.045
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.045
post embryonic development GO:0009791 2 0.045
ras protein signal transduction GO:0007265 73 0.045
guanosine containing compound catabolic process GO:1901069 239 0.044
purine containing compound catabolic process GO:0072523 411 0.044
response to lipopolysaccharide GO:0032496 70 0.043
viral process GO:0016032 146 0.043
Human
regulation of cell differentiation GO:0045595 393 0.043
nucleoside phosphate catabolic process GO:1901292 412 0.043
negative regulation of apoptotic process GO:0043066 316 0.043
regulation of intracellular transport GO:0032386 195 0.043
hemopoiesis GO:0030097 180 0.042
Human
positive regulation of lymphocyte proliferation GO:0050671 46 0.042
nucleotide catabolic process GO:0009166 408 0.042
positive regulation of cellular amine metabolic process GO:0033240 7 0.042
chemical homeostasis GO:0048878 306 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
gtp catabolic process GO:0006184 237 0.041
positive regulation of mononuclear cell proliferation GO:0032946 47 0.041
leukocyte differentiation GO:0002521 98 0.041
Human
regulation of protein localization GO:0032880 296 0.041
response to lipid GO:0033993 206 0.040
leukocyte migration GO:0050900 107 0.040
regulation of cell activation GO:0050865 125 0.039
Human
cation transport GO:0006812 331 0.039
purine nucleoside triphosphate catabolic process GO:0009146 392 0.039
ribonucleoside triphosphate catabolic process GO:0009203 391 0.039
stress activated protein kinase signaling cascade GO:0031098 94 0.039
positive regulation of developmental process GO:0051094 314 0.038
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.038
hematopoietic or lymphoid organ development GO:0048534 186 0.038
Human
vesicle mediated transport GO:0016192 371 0.038
positive regulation of cell migration GO:0030335 172 0.038
positive regulation of cellular component biogenesis GO:0044089 158 0.038
positive regulation of nucleotide metabolic process GO:0045981 230 0.038
regulation of kinase activity GO:0043549 314 0.038
positive regulation of t cell activation GO:0050870 54 0.038
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.037
Human
purine ribonucleoside catabolic process GO:0046130 398 0.037
organophosphate biosynthetic process GO:0090407 163 0.037
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
carbohydrate derivative biosynthetic process GO:1901137 207 0.037
negative regulation of cell death GO:0060548 345 0.037
purine nucleotide catabolic process GO:0006195 405 0.037
multi organism cellular process GO:0044764 156 0.037
Human
single organism cellular localization GO:1902580 332 0.037
regulation of mononuclear cell proliferation GO:0032944 65 0.036
Human
guanosine containing compound metabolic process GO:1901068 244 0.036
regulation of gtp catabolic process GO:0033124 180 0.036
regulation of immune effector process GO:0002697 91 0.036
positive regulation of leukocyte activation GO:0002696 80 0.036
positive regulation of programmed cell death GO:0043068 249 0.036
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
ribonucleoside catabolic process GO:0042454 406 0.036
organophosphate catabolic process GO:0046434 430 0.035
sequestering of metal ion GO:0051238 24 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
single organism cell adhesion GO:0098602 179 0.034
cellular cation homeostasis GO:0030003 163 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.034
positive regulation of leukocyte proliferation GO:0070665 48 0.034
regulation of apoptotic signaling pathway GO:2001233 175 0.034
viral life cycle GO:0019058 132 0.034
Human
positive regulation of cellular component movement GO:0051272 181 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
Human
regulation of cytoplasmic transport GO:1903649 149 0.034
mononuclear cell proliferation GO:0032943 71 0.034
Human
multicellular organismal aging GO:0010259 3 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
regulation of ion transport GO:0043269 189 0.033
positive regulation of innate immune response GO:0045089 79 0.033
calcium ion transport GO:0006816 147 0.033
ribonucleotide catabolic process GO:0009261 405 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.033
positive regulation of cell proliferation GO:0008284 301 0.033
regulation of protein secretion GO:0050708 86 0.033
determination of adult lifespan GO:0008340 2 0.033
positive regulation of protein transport GO:0051222 135 0.033
regulation of nucleoside metabolic process GO:0009118 209 0.032
regulation of transferase activity GO:0051338 355 0.032
cell development GO:0048468 328 0.032
cellular response to lipid GO:0071396 127 0.031
positive regulation of cell motility GO:2000147 177 0.031
actin filament based process GO:0030029 224 0.031
divalent metal ion transport GO:0070838 152 0.031
myeloid dendritic cell activation GO:0001773 4 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.030
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.030
negative regulation of multicellular organismal process GO:0051241 317 0.030
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.030
regulation of cellular response to stress GO:0080135 244 0.030
regulation of proteolysis GO:0030162 293 0.030
regulation of stress activated mapk cascade GO:0032872 84 0.030
regulation of cellular ketone metabolic process GO:0010565 50 0.030
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
Human
lipid metabolic process GO:0006629 381 0.030
eosinophil activation involved in immune response GO:0002278 2 0.030
regulation of lymphocyte activation GO:0051249 103 0.030
Human
protein catabolic process GO:0030163 325 0.030
gtp metabolic process GO:0046039 239 0.030
female gamete generation GO:0007292 2 0.030
cellular response to dna damage stimulus GO:0006974 379 0.030
Human
positive regulation of lymphocyte activation GO:0051251 73 0.030
activation of innate immune response GO:0002218 55 0.029
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.029
regulation of secretion by cell GO:1903530 177 0.029
positive regulation of catabolic process GO:0009896 310 0.029
cellular response to biotic stimulus GO:0071216 71 0.029
positive regulation of proteolysis GO:0045862 142 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
Human
response to molecule of bacterial origin GO:0002237 82 0.029
negative regulation of multi organism process GO:0043901 92 0.029
Human
protein targeting GO:0006605 187 0.028
extrinsic apoptotic signaling pathway GO:0097191 119 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
regulation of gtpase activity GO:0043087 180 0.028
regulation of innate immune response GO:0045088 97 0.028
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
protein import into nucleus GO:0006606 104 0.027
oogenesis GO:0048477 2 0.027
cellular homeostasis GO:0019725 196 0.027
cellular metal ion homeostasis GO:0006875 146 0.027
carbohydrate metabolic process GO:0005975 207 0.027
protein maturation GO:0051604 233 0.027
Human
regulation of cytokine secretion GO:0050707 57 0.027
regulation of vesicle mediated transport GO:0060627 130 0.027
regulation of dna metabolic process GO:0051052 153 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
regulation of leukocyte activation GO:0002694 115 0.026
Human
positive regulation of leukocyte chemotaxis GO:0002690 38 0.026
apoptotic signaling pathway GO:0097190 268 0.026
Human
regulation of endopeptidase activity GO:0052548 170 0.026
cell chemotaxis GO:0060326 112 0.026
intracellular protein transport GO:0006886 270 0.026
chemotaxis GO:0006935 157 0.026
protein localization to organelle GO:0033365 280 0.026
positive regulation of intracellular transport GO:0032388 104 0.026
regulation of leukocyte proliferation GO:0070663 67 0.026
Human
detection of stimulus GO:0051606 85 0.026
nitrogen compound transport GO:0071705 191 0.026
regulation of cysteine type endopeptidase activity GO:2000116 127 0.026
circulatory system development GO:0072359 262 0.026
regulation of cytoskeleton organization GO:0051493 177 0.026
protein processing GO:0016485 226 0.025
Human
divalent inorganic cation transport GO:0072511 158 0.025
actin filament organization GO:0007015 128 0.025
regulation of nucleotide catabolic process GO:0030811 205 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
maintenance of location GO:0051235 112 0.025
cyclic nucleotide metabolic process GO:0009187 82 0.025
positive regulation of secretion GO:0051047 116 0.025
interleukin 1 production GO:0032612 26 0.025
positive regulation of stress activated mapk cascade GO:0032874 60 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
regulation of small gtpase mediated signal transduction GO:0051056 156 0.024
zymogen activation GO:0031638 70 0.024
Human
erk1 and erk2 cascade GO:0070371 104 0.024
negative regulation of programmed cell death GO:0043069 321 0.024
ion homeostasis GO:0050801 230 0.024
positive regulation of cytokine production GO:0001819 167 0.024
positive regulation of organelle organization GO:0010638 195 0.024
cellular response to cytokine stimulus GO:0071345 181 0.024
organonitrogen compound biosynthetic process GO:1901566 200 0.024
metal ion transport GO:0030001 272 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.023
Human
cellular protein catabolic process GO:0044257 261 0.023
defense response to bacterium GO:0042742 63 0.023
activation of cysteine type endopeptidase activity GO:0097202 57 0.023
Human
regulation of purine nucleotide catabolic process GO:0033121 205 0.023
cytokine mediated signaling pathway GO:0019221 109 0.023
nuclear transport GO:0051169 179 0.023
regulation of erk1 and erk2 cascade GO:0070372 99 0.023
negative regulation of interferon beta production GO:0032688 4 0.023
cellular response to tumor necrosis factor GO:0071356 63 0.023
dephosphorylation GO:0016311 209 0.023
cell morphogenesis GO:0000902 296 0.023
response to wounding GO:0009611 168 0.023
immune response regulating signaling pathway GO:0002764 97 0.023
Human
myoblast fusion GO:0007520 1 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.022
transmembrane transport GO:0055085 399 0.022
nervous system development GO:0007399 293 0.022
regulation of actin filament based process GO:0032970 141 0.022
regulation of tumor necrosis factor production GO:0032680 43 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.022
pattern recognition receptor signaling pathway GO:0002221 48 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
regulation of metal ion transport GO:0010959 120 0.022
response to tumor necrosis factor GO:0034612 76 0.022
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
positive regulation of response to external stimulus GO:0032103 88 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
negative regulation of developmental process GO:0051093 247 0.021
glycoprotein metabolic process GO:0009100 110 0.021
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.021
sensory perception of pain GO:0019233 4 0.021
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.021
protein ubiquitination GO:0016567 314 0.021
negative regulation of cell cycle GO:0045786 193 0.021
cardiovascular system development GO:0072358 262 0.021
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.021
Human
positive regulation of protein phosphorylation GO:0001934 313 0.021
leukocyte proliferation GO:0070661 74 0.021
Human
system process GO:0003008 349 0.021
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.021
neuromuscular junction development GO:0007528 3 0.021
positive regulation of gtp catabolic process GO:0033126 166 0.020
locomotory behavior GO:0007626 1 0.020
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.020
positive regulation of t cell proliferation GO:0042102 33 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
calcium ion homeostasis GO:0055074 122 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
negative regulation of protein modification process GO:0031400 200 0.020
positive regulation of transferase activity GO:0051347 227 0.020
tumor necrosis factor production GO:0032640 43 0.020
regulation of t cell activation GO:0050863 77 0.020
cellular ion homeostasis GO:0006873 168 0.020
wound healing GO:0042060 115 0.020
syncytium formation by plasma membrane fusion GO:0000768 2 0.020
endocytosis GO:0006897 159 0.020
stress activated mapk cascade GO:0051403 93 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
cellular lipid metabolic process GO:0044255 303 0.020
b cell activation GO:0042113 33 0.020
Human
single organism carbohydrate metabolic process GO:0044723 193 0.020
positive regulation of cytokine secretion GO:0050715 42 0.020
regulation of response to biotic stimulus GO:0002831 55 0.020
camp metabolic process GO:0046058 61 0.020
myeloid cell differentiation GO:0030099 117 0.019
Human
memory GO:0007613 3 0.019
regulation of homeostatic process GO:0032844 121 0.019
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.019
regulation of binding GO:0051098 111 0.019
Human
chromatin organization GO:0006325 351 0.019
positive regulation of protein secretion GO:0050714 60 0.019
regulation of protein complex assembly GO:0043254 147 0.019
regulation of leukocyte chemotaxis GO:0002688 46 0.019
cellular response to external stimulus GO:0071496 111 0.019
Human
regulation of interferon gamma production GO:0032649 36 0.019
positive regulation of kinase activity GO:0033674 204 0.019
peptidyl tyrosine modification GO:0018212 170 0.019
inflammatory response GO:0006954 79 0.019
cytokine secretion GO:0050663 64 0.019
response to fungus GO:0009620 4 0.019
negative regulation of cytokine production GO:0001818 82 0.019
positive regulation of cytoplasmic transport GO:1903651 82 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.019
cellular component morphogenesis GO:0032989 314 0.019
response to growth factor GO:0070848 205 0.019
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.019
divalent inorganic cation homeostasis GO:0072507 136 0.019
positive regulation of cytoskeleton organization GO:0051495 83 0.018
jnk cascade GO:0007254 80 0.018
mitotic cell cycle GO:0000278 326 0.018
regulation of cell cycle process GO:0010564 266 0.018
cell fate determination GO:0001709 3 0.018
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.018
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.018
regulation of behavior GO:0050795 82 0.018
positive regulation of peptidase activity GO:0010952 88 0.018
regulation of rho protein signal transduction GO:0035023 79 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
chromatin modification GO:0016568 298 0.018
covalent chromatin modification GO:0016569 254 0.018
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.018
Human
positive regulation of protein complex assembly GO:0031334 86 0.017
lipid biosynthetic process GO:0008610 177 0.017
regulation of cell adhesion GO:0030155 166 0.017
interleukin 1 beta production GO:0032611 22 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
regulation of calcium ion transport GO:0051924 79 0.017
spermatid differentiation GO:0048515 4 0.017
cell activation involved in immune response GO:0002263 30 0.017
positive regulation of interleukin 1 beta secretion GO:0050718 11 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
glycoprotein biosynthetic process GO:0009101 91 0.017
negative regulation of transport GO:0051051 176 0.017
positive regulation of endopeptidase activity GO:0010950 84 0.017
positive regulation of behavior GO:0048520 60 0.017
response to radiation GO:0009314 151 0.017
Human
response to interleukin 1 GO:0070555 47 0.017
innate immune response activating signal transduction GO:0002758 48 0.017
negative regulation of viral process GO:0048525 66 0.017
Human
regulation of chemotaxis GO:0050920 74 0.017
mitotic cell cycle process GO:1903047 286 0.017
mature dendritic cell differentiation GO:0097029 2 0.017
granulocyte migration GO:0097530 40 0.017
reactive nitrogen species metabolic process GO:2001057 3 0.017
negative regulation of vasculature development GO:1901343 43 0.017
protein targeting to nucleus GO:0044744 104 0.017
regulation of ras gtpase activity GO:0032318 128 0.016
cation homeostasis GO:0055080 189 0.016
positive regulation of jnk cascade GO:0046330 52 0.016
regulation of protein processing GO:0070613 150 0.016
Human
positive regulation of leukocyte migration GO:0002687 46 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
cellular chemical homeostasis GO:0055082 180 0.016
epithelial cell migration GO:0010631 119 0.016
myeloid leukocyte activation GO:0002274 34 0.016
angiogenesis GO:0001525 147 0.016
positive regulation of ion transport GO:0043270 87 0.016
response to triacyl bacterial lipopeptide GO:0071725 2 0.016
positive regulation of astrocyte chemotaxis GO:2000464 1 0.016
positive regulation of camp metabolic process GO:0030816 41 0.016
lymphocyte differentiation GO:0030098 35 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
positive regulation of t cell migration GO:2000406 13 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
regulation of interleukin 10 secretion GO:2001179 4 0.016
single organismal cell cell adhesion GO:0016337 148 0.016
actin cytoskeleton organization GO:0030036 207 0.016
cellular calcium ion homeostasis GO:0006874 117 0.016
cellular response to abiotic stimulus GO:0071214 117 0.016
Human
regulation of hormone levels GO:0010817 125 0.016
cellular divalent inorganic cation homeostasis GO:0072503 128 0.016
positive regulation of tumor necrosis factor production GO:0032760 21 0.015
myeloid leukocyte differentiation GO:0002573 60 0.015
Human
protein acylation GO:0043543 138 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.015
regulation of camp metabolic process GO:0030814 52 0.015
small molecule biosynthetic process GO:0044283 157 0.015
digestive tract development GO:0048565 75 0.015
spermatid development GO:0007286 4 0.015
humoral immune response GO:0006959 49 0.015
membrane organization GO:0061024 292 0.015
oocyte differentiation GO:0009994 2 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
receptor metabolic process GO:0043112 81 0.015
regulation of cell development GO:0060284 161 0.015
regulation of cellular component size GO:0032535 82 0.015
segmentation GO:0035282 4 0.015
blood vessel development GO:0001568 172 0.015
protein localization to nucleus GO:0034504 136 0.015
positive regulation of apoptotic signaling pathway GO:2001235 70 0.015
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.015
peripheral nervous system development GO:0007422 2 0.015
positive regulation of defense response GO:0031349 87 0.015
blood vessel morphogenesis GO:0048514 162 0.015
regulation of jnk cascade GO:0046328 73 0.014
myeloid dendritic cell differentiation GO:0043011 3 0.014
regulation of interferon alpha biosynthetic process GO:0045354 4 0.014
mhc class ii biosynthetic process GO:0045342 4 0.014
leukocyte activation involved in immune response GO:0002366 30 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
eosinophil degranulation GO:0043308 2 0.014
alcohol metabolic process GO:0006066 114 0.014
interferon beta production GO:0032608 23 0.014
regulation of peptide transport GO:0090087 62 0.014
negative regulation of transferase activity GO:0051348 124 0.014
oocyte development GO:0048599 1 0.014
peptide transport GO:0015833 74 0.014
blastoderm segmentation GO:0007350 2 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
interleukin 8 production GO:0032637 51 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
negative regulation of alpha beta t cell activation GO:0046636 3 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
calcium ion transport into cytosol GO:0060402 48 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
cell projection organization GO:0030030 252 0.014
leukocyte chemotaxis GO:0030595 76 0.014
t cell differentiation in thymus GO:0033077 4 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
neurological system process GO:0050877 163 0.014
response to decreased oxygen levels GO:0036293 96 0.014
organic hydroxy compound metabolic process GO:1901615 147 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
single organism membrane organization GO:0044802 268 0.014
compound eye development GO:0048749 1 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
cellular protein complex assembly GO:0043623 188 0.013
oxidation reduction process GO:0055114 396 0.013
histone modification GO:0016570 251 0.013
tissue migration GO:0090130 119 0.013
regulation of cell division GO:0051302 116 0.013
metal ion homeostasis GO:0055065 169 0.013
negative regulation of proteolysis GO:0045861 132 0.013
Human
interleukin 10 production GO:0032613 17 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
response to drug GO:0042493 81 0.013
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.013
regulation of interleukin 1 beta production GO:0032651 18 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013

AIM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.019
musculoskeletal system disease DOID:17 223 0.019
disease of cellular proliferation DOID:14566 174 0.018
sensory system disease DOID:0050155 203 0.016
nervous system disease DOID:863 431 0.016
cancer DOID:162 167 0.014
organ system cancer DOID:0050686 164 0.014
connective tissue disease DOID:65 109 0.014
eye and adnexa disease DOID:1492 150 0.013
central nervous system disease DOID:331 186 0.013