Homo sapiens

78 known processes

MED24

mediator complex subunit 24

(Aliases: THRAP4,hTRAP100,CRSP100,ARC100,CRSP4,TRAP100,MGC8748,DRIP100,KIAA0130)

MED24 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.545
organ morphogenesis GO:0009887 147 0.384
Zebrafish
tube development GO:0035295 125 0.368
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.366
anatomical structure formation involved in morphogenesis GO:0048646 284 0.334
axis elongation GO:0003401 4 0.327
somitogenesis GO:0001756 2 0.299
segmentation GO:0035282 4 0.285
androgen receptor signaling pathway GO:0030521 34 0.284
neural tube formation GO:0001841 3 0.281
morphogenesis of a polarized epithelium GO:0001738 3 0.259
single organism cellular localization GO:1902580 332 0.248
dna templated transcription initiation GO:0006352 35 0.239
negative regulation of cell proliferation GO:0008285 228 0.231
cell development GO:0048468 328 0.201
Zebrafish
intracellular receptor signaling pathway GO:0030522 104 0.183
embryonic epithelial tube formation GO:0001838 4 0.151
establishment of protein localization to organelle GO:0072594 172 0.143
stem cell differentiation GO:0048863 93 0.139
positive regulation of developmental process GO:0051094 314 0.133
protein localization to organelle GO:0033365 280 0.120
primary neural tube formation GO:0014020 3 0.115
androgen biosynthetic process GO:0006702 3 0.113
response to oxygen containing compound GO:1901700 369 0.108
chromatin organization GO:0006325 351 0.105
regulation of establishment of protein localization GO:0070201 242 0.103
tube closure GO:0060606 3 0.101
establishment of planar polarity GO:0001736 3 0.101
peripheral nervous system development GO:0007422 2 0.101
cellular macromolecular complex assembly GO:0034622 324 0.101
cytoplasmic transport GO:0016482 379 0.098
positive regulation of transport GO:0051050 336 0.095
tissue morphogenesis GO:0048729 96 0.095
Zebrafish
embryonic morphogenesis GO:0048598 85 0.087
establishment of tissue polarity GO:0007164 3 0.085
regulation of cell differentiation GO:0045595 393 0.085
circulatory system development GO:0072359 262 0.085
negative regulation of cell differentiation GO:0045596 171 0.085
post embryonic development GO:0009791 2 0.084
neural tube closure GO:0001843 3 0.084
negative regulation of developmental process GO:0051093 247 0.082
intracellular protein transport GO:0006886 270 0.080
cellular amino acid metabolic process GO:0006520 116 0.080
single organism nuclear import GO:1902593 104 0.078
tube morphogenesis GO:0035239 95 0.077
growth GO:0040007 202 0.075
nucleocytoplasmic transport GO:0006913 176 0.075
cell cycle phase transition GO:0044770 173 0.074
oogenesis GO:0048477 2 0.072
protein targeting to nucleus GO:0044744 104 0.071
multicellular organismal aging GO:0010259 3 0.070
oligodendrocyte differentiation GO:0048709 7 0.069
cardiovascular system development GO:0072358 262 0.067
vesicle mediated transport GO:0016192 371 0.067
nervous system development GO:0007399 293 0.066
Zebrafish
protein import into nucleus GO:0006606 104 0.065
nuclear transport GO:0051169 179 0.065
regulation of cellular ketone metabolic process GO:0010565 50 0.062
response to hormone GO:0009725 175 0.061
regulation of intracellular transport GO:0032386 195 0.060
protein localization to nucleus GO:0034504 136 0.059
female gamete generation GO:0007292 2 0.058
protein import GO:0017038 130 0.058
regulation of nucleocytoplasmic transport GO:0046822 98 0.056
negative regulation of apoptotic process GO:0043066 316 0.055
regulation of protein transport GO:0051223 213 0.054
epithelium development GO:0060429 227 0.054
regulation of cell cycle GO:0051726 393 0.053
oocyte differentiation GO:0009994 2 0.052
cellular response to oxygen containing compound GO:1901701 276 0.052
positive regulation of protein import into nucleus GO:0042307 46 0.051
oligodendrocyte development GO:0014003 6 0.051
neurogenesis GO:0022008 169 0.050
Zebrafish
developmental growth GO:0048589 48 0.050
regulation of protein import into nucleus GO:0042306 78 0.049
negative regulation of transport GO:0051051 176 0.049
response to other organism GO:0051707 261 0.049
determination of adult lifespan GO:0008340 2 0.048
regulation of intracellular protein transport GO:0033157 123 0.047
heart development GO:0007507 95 0.046
canonical wnt signaling pathway GO:0060070 116 0.045
immune system development GO:0002520 195 0.043
Zebrafish
positive regulation of cell differentiation GO:0045597 211 0.043
regulation of protein localization GO:0032880 296 0.043
negative regulation of protein metabolic process GO:0051248 391 0.043
cellular component morphogenesis GO:0032989 314 0.042
non canonical wnt signaling pathway GO:0035567 14 0.042
negative regulation of cell cycle GO:0045786 193 0.042
protein targeting GO:0006605 187 0.042
mapk cascade GO:0000165 288 0.041
generation of neurons GO:0048699 152 0.040
Zebrafish
oocyte development GO:0048599 1 0.040
histone deubiquitination GO:0016578 16 0.038
regulation of cytoplasmic transport GO:1903649 149 0.038
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
regulation of protein localization to nucleus GO:1900180 85 0.036
endocytosis GO:0006897 159 0.036
cellular response to endogenous stimulus GO:0071495 336 0.036
cellular response to dna damage stimulus GO:0006974 379 0.036
muscle structure development GO:0061061 98 0.035
defense response GO:0006952 315 0.034
lipid biosynthetic process GO:0008610 177 0.034
response to organonitrogen compound GO:0010243 156 0.034
axis elongation involved in somitogenesis GO:0090245 1 0.034
covalent chromatin modification GO:0016569 254 0.033
actin filament based process GO:0030029 224 0.033
negative regulation of mitotic cell cycle GO:0045930 102 0.032
eye photoreceptor cell differentiation GO:0001754 2 0.032
Zebrafish
cellular response to external stimulus GO:0071496 111 0.031
regulation of protein targeting GO:1903533 91 0.031
morphogenesis of an epithelium GO:0002009 60 0.031
cellular protein complex assembly GO:0043623 188 0.031
embryo development GO:0009790 123 0.030
response to biotic stimulus GO:0009607 276 0.030
lens development in camera type eye GO:0002088 2 0.030
regulation of mapk cascade GO:0043408 262 0.029
metencephalon development GO:0022037 2 0.029
regulation of protein serine threonine kinase activity GO:0071900 179 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.028
negative regulation of cellular component organization GO:0051129 235 0.028
positive regulation of cell death GO:0010942 263 0.027
mitotic cell cycle phase transition GO:0044772 162 0.027
response to extracellular stimulus GO:0009991 85 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
response to growth factor GO:0070848 205 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
mitotic cell cycle process GO:1903047 286 0.026
negative regulation of cytoplasmic transport GO:1903650 46 0.026
cell morphogenesis GO:0000902 296 0.026
maintenance of protein location in cell GO:0032507 56 0.026
regulation of protein stability GO:0031647 87 0.025
positive regulation of intracellular transport GO:0032388 104 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
mrna metabolic process GO:0016071 175 0.025
nuclear import GO:0051170 106 0.025
negative regulation of protein transport GO:0051224 75 0.025
regulation of organ morphogenesis GO:2000027 24 0.025
photoreceptor cell differentiation GO:0046530 2 0.025
Zebrafish
regulation of wnt signaling pathway GO:0030111 123 0.025
positive regulation of cytoplasmic transport GO:1903651 82 0.025
anterior posterior axis specification embryo GO:0008595 2 0.025
negative regulation of programmed cell death GO:0043069 321 0.025
negative regulation of phosphorylation GO:0042326 174 0.025
chromatin modification GO:0016568 298 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
positive regulation of growth GO:0045927 58 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
leukocyte activation GO:0045321 164 0.023
regulation of receptor activity GO:0010469 47 0.023
somite development GO:0061053 7 0.023
regulation of cell development GO:0060284 161 0.023
regulation of transferase activity GO:0051338 355 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
epithelial tube morphogenesis GO:0060562 38 0.023
negative regulation of protein localization to nucleus GO:1900181 34 0.022
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.022
protein modification by small protein removal GO:0070646 92 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
tripartite regional subdivision GO:0007351 2 0.022
cellular component assembly involved in morphogenesis GO:0010927 73 0.022
regulation of growth GO:0040008 165 0.022
cellular ketone metabolic process GO:0042180 80 0.022
immune response GO:0006955 307 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
response to external biotic stimulus GO:0043207 261 0.022
locomotory behavior GO:0007626 1 0.022
regulation of dna metabolic process GO:0051052 153 0.022
protein dna complex assembly GO:0065004 64 0.022
response to oxygen levels GO:0070482 100 0.021
transcription factor import into nucleus GO:0042991 40 0.021
protein alkylation GO:0008213 74 0.021
digestive system development GO:0055123 75 0.021
amine metabolic process GO:0009308 44 0.021
maintenance of location GO:0051235 112 0.021
pattern specification process GO:0007389 43 0.021
endosomal transport GO:0016197 129 0.021
response to abiotic stimulus GO:0009628 336 0.021
negative regulation of cell death GO:0060548 345 0.020
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.020
positive regulation of protein transport GO:0051222 135 0.020
maintenance of location in cell GO:0051651 62 0.020
hemopoiesis GO:0030097 180 0.020
rna splicing GO:0008380 131 0.019
regeneration GO:0031099 4 0.019
biological adhesion GO:0022610 331 0.019
regulation of transcription factor import into nucleus GO:0042990 39 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
positive regulation of intracellular protein transport GO:0090316 76 0.019
innate immune response GO:0045087 178 0.019
regulation of kinase activity GO:0043549 314 0.019
lipid metabolic process GO:0006629 381 0.019
schwann cell development GO:0014044 1 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.019
ribonucleoprotein complex subunit organization GO:0071826 81 0.018
histone methylation GO:0016571 60 0.018
pharynx development GO:0060465 1 0.018
blastoderm segmentation GO:0007350 2 0.018
protein dna complex subunit organization GO:0071824 80 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
neuron development GO:0048666 113 0.017
Zebrafish
cell adhesion GO:0007155 325 0.017
single organism reproductive process GO:0044702 98 0.017
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.017
myosin filament organization GO:0031033 2 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
meiosis i GO:0007127 4 0.017
protein processing GO:0016485 226 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
regulation of peptidase activity GO:0052547 180 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
reproductive process GO:0022414 106 0.017
thymus development GO:0048538 3 0.017
Zebrafish
regulation of chromosome organization GO:0033044 103 0.017
response to peptide GO:1901652 65 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
muscle cell differentiation GO:0042692 63 0.017
regulation of lymphocyte activation GO:0051249 103 0.016
regulation of cell cycle process GO:0010564 266 0.016
ribonucleoprotein complex assembly GO:0022618 78 0.016
mitotic cell cycle GO:0000278 326 0.016
blood vessel morphogenesis GO:0048514 162 0.016
cellular response to nutrient levels GO:0031669 69 0.016
embryo development ending in birth or egg hatching GO:0009792 34 0.016
embryonic placenta development GO:0001892 1 0.016
regulation of hormone levels GO:0010817 125 0.016
nitrogen compound transport GO:0071705 191 0.016
single organism membrane organization GO:0044802 268 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.016
central nervous system development GO:0007417 123 0.016
ras protein signal transduction GO:0007265 73 0.016
cellular component disassembly GO:0022411 92 0.016
regulation of protein kinase activity GO:0045859 289 0.016
single organism cell adhesion GO:0098602 179 0.016
anterior posterior axis specification GO:0009948 2 0.015
response to fungus GO:0009620 4 0.015
response to transforming growth factor beta GO:0071559 94 0.015
lymphocyte activation GO:0046649 133 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
hindbrain development GO:0030902 3 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
wnt signaling pathway planar cell polarity pathway GO:0060071 5 0.015
cell activation GO:0001775 213 0.015
defense response to other organism GO:0098542 129 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
mitochondrion organization GO:0007005 156 0.015
response to decreased oxygen levels GO:0036293 96 0.015
protein catabolic process GO:0030163 325 0.015
maintenance of protein location GO:0045185 57 0.015
protein maturation GO:0051604 233 0.015
developmental growth involved in morphogenesis GO:0060560 23 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
cellular response to hormone stimulus GO:0032870 125 0.014
regulation of secretion GO:0051046 194 0.014
vasculature development GO:0001944 181 0.014
developmental process involved in reproduction GO:0003006 66 0.014
organelle localization GO:0051640 84 0.014
cell division GO:0051301 168 0.014
organelle assembly GO:0070925 176 0.014
dna repair GO:0006281 198 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.014
cell cell signaling GO:0007267 155 0.014
thyroid hormone generation GO:0006590 2 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.014
regulation of secretion by cell GO:1903530 177 0.014
cofactor metabolic process GO:0051186 87 0.014
regulation of immune effector process GO:0002697 91 0.014
negative regulation of protein import into nucleus GO:0042308 30 0.014
dephosphorylation GO:0016311 209 0.014
hindlimb morphogenesis GO:0035137 2 0.014
eye development GO:0001654 42 0.013
Zebrafish
neuron projection development GO:0031175 106 0.013
leukocyte differentiation GO:0002521 98 0.013
rna processing GO:0006396 255 0.013
positive regulation of immune system process GO:0002684 283 0.013
regionalization GO:0003002 29 0.013
negative regulation of wnt signaling pathway GO:0030178 69 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
multi organism reproductive process GO:0044703 54 0.013
positive regulation of peptidase activity GO:0010952 88 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
Zebrafish
protein deubiquitination GO:0016579 79 0.013
erk1 and erk2 cascade GO:0070371 104 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
gtp metabolic process GO:0046039 239 0.013
myosin filament assembly GO:0031034 2 0.013
response to hypoxia GO:0001666 96 0.013
system process GO:0003008 349 0.013
gland development GO:0048732 48 0.013
Zebrafish
negative regulation of mapk cascade GO:0043409 56 0.012
ossification GO:0001503 121 0.012
regulation of histone modification GO:0031056 47 0.012
positive regulation of protein localization to nucleus GO:1900182 48 0.012
urogenital system development GO:0001655 65 0.012
schwann cell differentiation GO:0014037 1 0.012
convergent extension GO:0060026 1 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
metal ion homeostasis GO:0055065 169 0.012
methylation GO:0032259 106 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
regulation of multi organism process GO:0043900 157 0.012
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.012
regulation of meiosis GO:0040020 3 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
hair cell differentiation GO:0035315 2 0.012
brain development GO:0007420 97 0.012
response to nutrient levels GO:0031667 81 0.012
cell projection organization GO:0030030 252 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
cell cycle arrest GO:0007050 71 0.012
response to cytokine GO:0034097 232 0.012
neuromuscular junction development GO:0007528 3 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
actin cytoskeleton organization GO:0030036 207 0.011
positive regulation of proteolysis GO:0045862 142 0.011
multicellular organism reproduction GO:0032504 42 0.011
positive regulation of acute inflammatory response GO:0002675 2 0.011
regulation of cellular response to stress GO:0080135 244 0.011
spermatid development GO:0007286 4 0.011
positive regulation of cell development GO:0010720 92 0.011
vacuolar transport GO:0007034 34 0.011
cell cell recognition GO:0009988 4 0.011
reproductive structure development GO:0048608 55 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
secretion GO:0046903 254 0.011
ribonucleoprotein complex biogenesis GO:0022613 116 0.011
regulation of proteolysis GO:0030162 293 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
stem cell development GO:0048864 69 0.011
epithelial cell differentiation GO:0030855 141 0.011
secretion by cell GO:0032940 226 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.011
regulation of transcription by chromatin organization GO:0034401 1 0.011
developmental programmed cell death GO:0010623 3 0.011
zymogen activation GO:0031638 70 0.011
negative regulation of intracellular protein transport GO:0090317 42 0.011
digestive tract development GO:0048565 75 0.011
negative regulation of intracellular transport GO:0032387 60 0.011
adult locomotory behavior GO:0008344 1 0.011
stress activated mapk cascade GO:0051403 93 0.011
ion homeostasis GO:0050801 230 0.011
regulation of cellular component biogenesis GO:0044087 281 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
negative regulation of multi organism process GO:0043901 92 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
coenzyme metabolic process GO:0006732 65 0.010
positive regulation of endopeptidase activity GO:0010950 84 0.010
positive regulation of secretion by cell GO:1903532 108 0.010
ncrna metabolic process GO:0034660 108 0.010
peptidyl lysine acetylation GO:0018394 101 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.010
single organismal cell cell adhesion GO:0016337 148 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
nucleoside catabolic process GO:0009164 408 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010

MED24 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
musculoskeletal system disease DOID:17 223 0.018
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
organ system cancer DOID:0050686 164 0.018
eye and adnexa disease DOID:1492 150 0.014
gastrointestinal system cancer DOID:3119 52 0.013
retinal disease DOID:5679 118 0.011
retinal degeneration DOID:8466 89 0.011
eye disease DOID:5614 149 0.011