Homo sapiens

42 known processes

DCLRE1B

DNA cross-link repair 1B

(Aliases: DKFZp686C24187,FLJ12810,SNMIB,FLJ13998,APOLLO,SNM1B)

DCLRE1B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair GO:0006302 101 0.222
cellular response to dna damage stimulus GO:0006974 379 0.132
cell cycle g2 m phase transition GO:0044839 43 0.123
dna repair GO:0006281 198 0.110
double strand break repair via homologous recombination GO:0000724 50 0.078
protein catabolic process GO:0030163 325 0.077
post embryonic development GO:0009791 2 0.077
positive regulation of telomere maintenance GO:0032206 4 0.076
regulation of microtubule based process GO:0032886 74 0.069
mitotic cell cycle GO:0000278 326 0.067
protein oligomerization GO:0051259 173 0.055
negative regulation of telomere maintenance GO:0032205 9 0.055
regulation of microtubule cytoskeleton organization GO:0070507 61 0.054
multicellular organismal aging GO:0010259 3 0.054
chromatin modification GO:0016568 298 0.052
regulation of transferase activity GO:0051338 355 0.051
mitotic nuclear division GO:0007067 119 0.049
regulation of cellular component biogenesis GO:0044087 281 0.049
regulation of cell cycle process GO:0010564 266 0.048
chromosome segregation GO:0007059 114 0.048
replicative cell aging GO:0001302 3 0.048
determination of adult lifespan GO:0008340 2 0.047
microtubule cytoskeleton organization GO:0000226 176 0.044
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
chromatin organization GO:0006325 351 0.044
protein processing GO:0016485 226 0.043
protein localization to organelle GO:0033365 280 0.042
positive regulation of programmed cell death GO:0043068 249 0.040
regulation of protein catabolic process GO:0042176 155 0.039
positive regulation of apoptotic process GO:0043065 246 0.039
cellular macromolecule catabolic process GO:0044265 380 0.036
mitotic cell cycle process GO:1903047 286 0.036
covalent chromatin modification GO:0016569 254 0.035
negative regulation of protein metabolic process GO:0051248 391 0.035
recombinational repair GO:0000725 50 0.034
cellular amino acid metabolic process GO:0006520 116 0.034
microtubule based process GO:0007017 210 0.033
positive regulation of cell death GO:0010942 263 0.033
sister chromatid segregation GO:0000819 54 0.033
regulation of cellular ketone metabolic process GO:0010565 50 0.033
cell cycle checkpoint GO:0000075 117 0.033
positive regulation of cell cycle process GO:0090068 106 0.032
cell division GO:0051301 168 0.029
cellular protein catabolic process GO:0044257 261 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.029
cellular response to abiotic stimulus GO:0071214 117 0.029
dna replication GO:0006260 116 0.029
protein localization to chromosome GO:0034502 30 0.028
negative regulation of protein processing GO:0010955 142 0.028
positive regulation of cell proliferation GO:0008284 301 0.028
positive regulation of cell cycle GO:0045787 140 0.028
mitotic cell cycle phase transition GO:0044772 162 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.028
female gamete generation GO:0007292 2 0.027
regulation of cytoskeleton organization GO:0051493 177 0.027
histone modification GO:0016570 251 0.027
mitochondrion organization GO:0007005 156 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
positive regulation of cellular component biogenesis GO:0044089 158 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
cellular component morphogenesis GO:0032989 314 0.025
cellular amine metabolic process GO:0044106 41 0.025
cellular ketone metabolic process GO:0042180 80 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
ubiquitin dependent protein catabolic process GO:0006511 206 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
protein maturation GO:0051604 233 0.024
rna processing GO:0006396 255 0.023
oogenesis GO:0048477 2 0.023
regulation of protein maturation GO:1903317 150 0.023
telomere maintenance via telomere lengthening GO:0010833 9 0.023
negative regulation of cell cycle GO:0045786 193 0.023
negative regulation of transferase activity GO:0051348 124 0.023
embryo development GO:0009790 123 0.023
tissue regeneration GO:0042246 3 0.022
protein homooligomerization GO:0051260 100 0.022
dna biosynthetic process GO:0071897 40 0.022
mitotic sister chromatid segregation GO:0000070 53 0.022
protein localization to chromosome telomeric region GO:0070198 6 0.021
regulation of proteolysis GO:0030162 293 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
negative regulation of catabolic process GO:0009895 104 0.021
organelle fission GO:0048285 149 0.021
vesicle mediated transport GO:0016192 371 0.021
regulation of kinase activity GO:0043549 314 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
purine nucleotide catabolic process GO:0006195 405 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
amine metabolic process GO:0009308 44 0.020
growth GO:0040007 202 0.020
positive regulation of protein complex assembly GO:0031334 86 0.020
regulation of proteasomal protein catabolic process GO:0061136 87 0.020
positive regulation of cytoskeleton organization GO:0051495 83 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
single organism cellular localization GO:1902580 332 0.020
negative regulation of organelle organization GO:0010639 126 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
regeneration GO:0031099 4 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
dna conformation change GO:0071103 113 0.019
positive regulation of organelle organization GO:0010638 195 0.019
ras protein signal transduction GO:0007265 73 0.019
nucleotide catabolic process GO:0009166 408 0.019
cell morphogenesis GO:0000902 296 0.019
nervous system development GO:0007399 293 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.018
regulation of cell cycle GO:0051726 393 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
mitotic cell cycle checkpoint GO:0007093 68 0.018
g2 m transition of mitotic cell cycle GO:0000086 41 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
regulation of protein kinase activity GO:0045859 289 0.018
locomotory behavior GO:0007626 1 0.018
cellular response to radiation GO:0071478 65 0.018
modification dependent protein catabolic process GO:0019941 209 0.017
oocyte development GO:0048599 1 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.017
organelle assembly GO:0070925 176 0.017
regulation of cellular protein catabolic process GO:1903362 96 0.017
cell adhesion GO:0007155 325 0.017
regulation of cellular response to stress GO:0080135 244 0.017
nuclear division GO:0000280 128 0.017
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.017
neuromuscular junction development GO:0007528 3 0.017
cell projection organization GO:0030030 252 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
cell cycle phase transition GO:0044770 173 0.016
regulation of chromosome segregation GO:0051983 44 0.016
reproductive process GO:0022414 106 0.016
lipid metabolic process GO:0006629 381 0.016
regulation of mitosis GO:0007088 63 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
adult locomotory behavior GO:0008344 1 0.016
regulation of cell division GO:0051302 116 0.016
negative regulation of mitotic cell cycle GO:0045930 102 0.016
regulation of protein processing GO:0070613 150 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.016
intracellular protein transport GO:0006886 270 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
positive regulation of protein polymerization GO:0032273 45 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
single organism membrane organization GO:0044802 268 0.015
glycoprotein metabolic process GO:0009100 110 0.015
spermatid differentiation GO:0048515 4 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
regulation of growth GO:0040008 165 0.015
peripheral nervous system development GO:0007422 2 0.015
response to abiotic stimulus GO:0009628 336 0.015
cellular lipid metabolic process GO:0044255 303 0.014
telomere maintenance GO:0000723 32 0.014
negative regulation of telomere maintenance via telomerase GO:0032211 5 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
negative regulation of protein maturation GO:1903318 142 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
apoptotic signaling pathway GO:0097190 268 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
purine containing compound catabolic process GO:0072523 411 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
organophosphate catabolic process GO:0046434 430 0.014
single organism reproductive process GO:0044702 98 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
positive regulation of mitotic cell cycle GO:0045931 60 0.014
response to radiation GO:0009314 151 0.014
biological adhesion GO:0022610 331 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
response to wounding GO:0009611 168 0.014
response to oxygen containing compound GO:1901700 369 0.014
chemical homeostasis GO:0048878 306 0.014
regulation of chromosome organization GO:0033044 103 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
striated muscle myosin thick filament assembly GO:0071688 2 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
oxidation reduction process GO:0055114 396 0.013
erythrocyte development GO:0048821 3 0.013
protein ubiquitination GO:0016567 314 0.013
anatomical structure homeostasis GO:0060249 100 0.013
cation transport GO:0006812 331 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
negative regulation of proteolysis GO:0045861 132 0.013
neurogenesis GO:0022008 169 0.013
metal ion transport GO:0030001 272 0.013
cilium organization GO:0044782 68 0.013
regulation of intracellular transport GO:0032386 195 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
cell development GO:0048468 328 0.013
protein acylation GO:0043543 138 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
mrna metabolic process GO:0016071 175 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
system process GO:0003008 349 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
dna dependent dna replication GO:0006261 44 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.013
gtp catabolic process GO:0006184 237 0.012
double strand break repair via single strand annealing GO:0045002 4 0.012
oocyte differentiation GO:0009994 2 0.012
nucleoside catabolic process GO:0009164 408 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
negative regulation of cell death GO:0060548 345 0.012
maintenance of location GO:0051235 112 0.012
cofactor metabolic process GO:0051186 87 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
hindbrain development GO:0030902 3 0.012
somatic stem cell division GO:0048103 1 0.012
actin filament based process GO:0030029 224 0.012
meiotic chromosome segregation GO:0045132 4 0.012
positive regulation of catabolic process GO:0009896 310 0.012
positive regulation of developmental process GO:0051094 314 0.012
dephosphorylation GO:0016311 209 0.012
membrane organization GO:0061024 292 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
regulation of homeostatic process GO:0032844 121 0.012
positive regulation of chromosome organization GO:2001252 41 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
response to fungus GO:0009620 4 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
methylation GO:0032259 106 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
cytoplasmic transport GO:0016482 379 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
cell fate determination GO:0001709 3 0.012
cell aging GO:0007569 52 0.011
myosin filament organization GO:0031033 2 0.011
negative regulation of developmental process GO:0051093 247 0.011
atp catabolic process GO:0006200 157 0.011
response to external biotic stimulus GO:0043207 261 0.011
regulation of dna replication GO:0006275 68 0.011
positive regulation of meiotic cell cycle GO:0051446 2 0.011
protein targeting GO:0006605 187 0.011
cell projection assembly GO:0030031 126 0.011
response to ionizing radiation GO:0010212 65 0.011
cell type specific apoptotic process GO:0097285 125 0.011
lipid biosynthetic process GO:0008610 177 0.011
macromolecule glycosylation GO:0043413 63 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
positive regulation of cell division GO:0051781 59 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
gtp metabolic process GO:0046039 239 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
secretion GO:0046903 254 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
cellular response to ionizing radiation GO:0071479 32 0.011
positive regulation of kinase activity GO:0033674 204 0.011
negative regulation of protein modification process GO:0031400 200 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
aging GO:0007568 66 0.011
rho protein signal transduction GO:0007266 26 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
compound eye development GO:0048749 1 0.010
negative regulation of dna metabolic process GO:0051053 57 0.010
spindle checkpoint GO:0031577 26 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
regulation of sister chromatid segregation GO:0033045 27 0.010
endomembrane system organization GO:0010256 196 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
small molecule biosynthetic process GO:0044283 157 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010

DCLRE1B disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.023
immune system disease DOID:2914 155 0.023
hematopoietic system disease DOID:74 100 0.018
cancer DOID:162 167 0.012
organ system cancer DOID:0050686 164 0.012
bone marrow disease DOID:4961 31 0.012
disease of metabolism DOID:0014667 295 0.011
central nervous system disease DOID:331 186 0.011
neurodegenerative disease DOID:1289 102 0.011
nervous system disease DOID:863 431 0.011