Homo sapiens

151 known processes

DNA2

DNA replication helicase 2 homolog (yeast)

(Aliases: FLJ10063,DNA2L,MGC133297,KIAA0083)

DNA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 379 0.288
chromosome segregation GO:0007059 114 0.283
glycosyl compound catabolic process GO:1901658 413 0.271
purine containing compound catabolic process GO:0072523 411 0.205
organophosphate catabolic process GO:0046434 430 0.165
nuclear division GO:0000280 128 0.164
purine ribonucleotide catabolic process GO:0009154 404 0.159
nucleotide catabolic process GO:0009166 408 0.156
purine ribonucleoside metabolic process GO:0046128 437 0.155
post embryonic development GO:0009791 2 0.148
ribonucleoside monophosphate catabolic process GO:0009158 158 0.136
nucleoside triphosphate metabolic process GO:0009141 422 0.135
organelle fission GO:0048285 149 0.132
ribonucleotide catabolic process GO:0009261 405 0.121
dna repair GO:0006281 198 0.120
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.120
regulation of cell cycle GO:0051726 393 0.117
nucleoside monophosphate catabolic process GO:0009125 159 0.107
microtubule based process GO:0007017 210 0.106
double strand break repair via homologous recombination GO:0000724 50 0.098
mitotic cell cycle GO:0000278 326 0.092
meiotic chromosome segregation GO:0045132 4 0.090
double strand break repair GO:0006302 101 0.086
ribonucleoside triphosphate metabolic process GO:0009199 412 0.085
purine nucleoside monophosphate catabolic process GO:0009128 158 0.084
nucleoside phosphate catabolic process GO:1901292 412 0.081
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.080
purine nucleoside triphosphate metabolic process GO:0009144 412 0.075
ribonucleoside catabolic process GO:0042454 406 0.074
dna recombination GO:0006310 77 0.072
ribonucleoside monophosphate metabolic process GO:0009161 187 0.072
nucleoside triphosphate catabolic process GO:0009143 394 0.072
purine nucleoside triphosphate catabolic process GO:0009146 392 0.063
atp catabolic process GO:0006200 157 0.062
mitotic cell cycle process GO:1903047 286 0.062
purine ribonucleoside catabolic process GO:0046130 398 0.061
regulation of cell cycle process GO:0010564 266 0.061
atp metabolic process GO:0046034 176 0.061
purine nucleotide catabolic process GO:0006195 405 0.058
response to abiotic stimulus GO:0009628 336 0.055
purine nucleoside catabolic process GO:0006152 398 0.055
recombinational repair GO:0000725 50 0.053
nucleoside monophosphate metabolic process GO:0009123 191 0.049
ribonucleoside triphosphate catabolic process GO:0009203 391 0.048
maintenance of location GO:0051235 112 0.047
response to radiation GO:0009314 151 0.047
regulation of cell division GO:0051302 116 0.046
embryo development GO:0009790 123 0.046
Worm
vesicle mediated transport GO:0016192 371 0.045
regulation of cellular amino acid metabolic process GO:0006521 6 0.045
nucleoside catabolic process GO:0009164 408 0.045
cellular component morphogenesis GO:0032989 314 0.043
cellular ketone metabolic process GO:0042180 80 0.043
centrosome organization GO:0051297 58 0.040
mitotic nuclear division GO:0007067 119 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
regulation of protein kinase activity GO:0045859 289 0.038
cellular amino acid metabolic process GO:0006520 116 0.038
positive regulation of hydrolase activity GO:0051345 331 0.037
cell fate determination GO:0001709 3 0.036
cell division GO:0051301 168 0.036
positive regulation of organelle organization GO:0010638 195 0.036
reproductive process GO:0022414 106 0.035
dna replication GO:0006260 116 0.035
positive regulation of cell proliferation GO:0008284 301 0.034
cellular amine metabolic process GO:0044106 41 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.031
multicellular organismal aging GO:0010259 3 0.031
mitotic cell cycle phase transition GO:0044772 162 0.031
rna processing GO:0006396 255 0.029
purine nucleoside monophosphate metabolic process GO:0009126 186 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
cellular macromolecule catabolic process GO:0044265 380 0.028
cellular response to radiation GO:0071478 65 0.028
regulation of kinase activity GO:0043549 314 0.028
negative regulation of cell cycle GO:0045786 193 0.028
organelle assembly GO:0070925 176 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
protein localization to organelle GO:0033365 280 0.027
negative regulation of cell cycle process GO:0010948 121 0.027
microtubule organizing center organization GO:0031023 62 0.027
negative regulation of cell death GO:0060548 345 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.026
blastocyst development GO:0001824 3 0.026
maintenance of protein location in cell GO:0032507 56 0.026
attachment of spindle microtubules to kinetochore GO:0008608 17 0.026
positive regulation of apoptotic process GO:0043065 246 0.025
regulation of cell cycle phase transition GO:1901987 126 0.025
cell morphogenesis GO:0000902 296 0.025
protein ubiquitination GO:0016567 314 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
negative regulation of programmed cell death GO:0043069 321 0.024
amine metabolic process GO:0009308 44 0.024
maintenance of location in cell GO:0051651 62 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
cellular response to ionizing radiation GO:0071479 32 0.023
cell cycle phase transition GO:0044770 173 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
regulation of transferase activity GO:0051338 355 0.023
regulation of cellular response to stress GO:0080135 244 0.023
positive regulation of cell cycle GO:0045787 140 0.023
single organism reproductive process GO:0044702 98 0.022
epithelium development GO:0060429 227 0.022
regulation of double strand break repair GO:2000779 22 0.022
protein catabolic process GO:0030163 325 0.021
apoptotic signaling pathway GO:0097190 268 0.021
embryonic epithelial tube formation GO:0001838 4 0.021
positive regulation of developmental process GO:0051094 314 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
microtubule cytoskeleton organization GO:0000226 176 0.021
endocytosis GO:0006897 159 0.021
positive regulation of kinase activity GO:0033674 204 0.021
regulation of meiotic cell cycle GO:0051445 4 0.020
anatomical structure formation involved in morphogenesis GO:0048646 284 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
positive regulation of gtp catabolic process GO:0033126 166 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
cytoplasmic transport GO:0016482 379 0.020
intracellular protein transport GO:0006886 270 0.020
regulation of protein localization GO:0032880 296 0.020
cell projection organization GO:0030030 252 0.019
regulation of proteolysis GO:0030162 293 0.019
growth GO:0040007 202 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
cellular protein catabolic process GO:0044257 261 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
cell part morphogenesis GO:0032990 137 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
protein oligomerization GO:0051259 173 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
negative regulation of organelle organization GO:0010639 126 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.019
regulation of protein catabolic process GO:0042176 155 0.018
leukocyte activation GO:0045321 164 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
determination of adult lifespan GO:0008340 2 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
negative regulation of protein metabolic process GO:0051248 391 0.017
response to ionizing radiation GO:0010212 65 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
nervous system development GO:0007399 293 0.017
oxidation reduction process GO:0055114 396 0.017
protein processing GO:0016485 226 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
intrinsic apoptotic signaling pathway GO:0097193 127 0.017
cell cycle g1 s phase transition GO:0044843 80 0.017
reproductive system development GO:0061458 56 0.017
female gamete generation GO:0007292 2 0.017
cellular response to abiotic stimulus GO:0071214 117 0.016
positive regulation of gtpase activity GO:0043547 166 0.016
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.016
cytokine production GO:0001816 247 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
lipid metabolic process GO:0006629 381 0.016
positive regulation of cell cycle process GO:0090068 106 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
cell activation GO:0001775 213 0.016
protein homooligomerization GO:0051260 100 0.016
regeneration GO:0031099 4 0.016
negative regulation of protein modification process GO:0031400 200 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
rna splicing GO:0008380 131 0.015
cell adhesion GO:0007155 325 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
cell projection morphogenesis GO:0048858 129 0.015
positive regulation of catabolic process GO:0009896 310 0.015
single organism membrane organization GO:0044802 268 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
single organism cellular localization GO:1902580 332 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
reproduction GO:0000003 63 0.015
negative regulation of dna metabolic process GO:0051053 57 0.015
regulation of establishment of protein localization GO:0070201 242 0.014
sister chromatid segregation GO:0000819 54 0.014
oogenesis GO:0048477 2 0.014
regulation of gtpase activity GO:0043087 180 0.014
developmental process involved in reproduction GO:0003006 66 0.014
positive regulation of immune system process GO:0002684 283 0.014
regulation of dna repair GO:0006282 47 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
regulation of response to dna damage stimulus GO:2001020 94 0.014
regulation of cell motility GO:2000145 299 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
mitotic sister chromatid segregation GO:0000070 53 0.014
rho protein signal transduction GO:0007266 26 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
regulation of dna metabolic process GO:0051052 153 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
microtubule anchoring GO:0034453 24 0.013
protein targeting GO:0006605 187 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
coenzyme metabolic process GO:0006732 65 0.013
cdc42 protein signal transduction GO:0032488 4 0.013
defense response GO:0006952 315 0.013
positive regulation of cell death GO:0010942 263 0.013
response to nitrogen compound GO:1901698 184 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
positive regulation of mitotic cell cycle GO:0045931 60 0.013
cell cycle checkpoint GO:0000075 117 0.013
membrane organization GO:0061024 292 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
chemical homeostasis GO:0048878 306 0.013
head development GO:0060322 108 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of cell cycle g2 m phase transition GO:1902749 22 0.013
mrna splicing via spliceosome GO:0000398 89 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
mitotic cell cycle checkpoint GO:0007093 68 0.012
regulation of immune response GO:0050776 201 0.012
receptor mediated endocytosis GO:0006898 84 0.012
somatic muscle development GO:0007525 1 0.012
centrosome cycle GO:0007098 32 0.012
generation of neurons GO:0048699 152 0.012
regulation of protein transport GO:0051223 213 0.012
secretion GO:0046903 254 0.012
maintenance of protein location GO:0045185 57 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
cell cycle g2 m phase transition GO:0044839 43 0.012
actin filament based process GO:0030029 224 0.012
ameboidal type cell migration GO:0001667 135 0.012
immune response GO:0006955 307 0.012
protein maturation GO:0051604 233 0.012
response to oxygen containing compound GO:1901700 369 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
chromatin organization GO:0006325 351 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
dna packaging GO:0006323 77 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
meiosis i GO:0007127 4 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
peripheral nervous system development GO:0007422 2 0.011
gtp metabolic process GO:0046039 239 0.011
spermatid differentiation GO:0048515 4 0.011
neural tube closure GO:0001843 3 0.011
endomembrane system organization GO:0010256 196 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
sex determination GO:0007530 3 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
central nervous system development GO:0007417 123 0.011
negative regulation of protein processing GO:0010955 142 0.011
male meiosis GO:0007140 1 0.011
regulation of chromosome segregation GO:0051983 44 0.011
tube morphogenesis GO:0035239 95 0.011
response to inorganic substance GO:0010035 127 0.011
biological adhesion GO:0022610 331 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
neurogenesis GO:0022008 169 0.011
regulation of cell differentiation GO:0045595 393 0.011
positive regulation of transport GO:0051050 336 0.011
regulation of response to external stimulus GO:0032101 222 0.011
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
regulation of cellular component movement GO:0051270 334 0.010
lymphocyte activation GO:0046649 133 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
regulation of double strand break repair via homologous recombination GO:0010569 11 0.010
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
g1 s transition of mitotic cell cycle GO:0000082 78 0.010
dna biosynthetic process GO:0071897 40 0.010
regulation of cell migration GO:0030334 289 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
mrna metabolic process GO:0016071 175 0.010

DNA2 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.154
hematopoietic system disease DOID:74 100 0.091
disease of cellular proliferation DOID:14566 174 0.027
cancer DOID:162 167 0.017
anemia DOID:2355 55 0.015
disease of metabolism DOID:0014667 295 0.011