Homo sapiens

39 known processes

PMVK

phosphomevalonate kinase

(Aliases: PMKA,PMKASE,HUMPMKI,PMK)

PMVK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oligosaccharide biosynthetic process GO:0009312 3 0.333
lipid metabolic process GO:0006629 381 0.104
cellular ketone metabolic process GO:0042180 80 0.095
protein localization to membrane GO:0072657 160 0.084
carbohydrate metabolic process GO:0005975 207 0.071
intracellular protein transport GO:0006886 270 0.068
post embryonic development GO:0009791 2 0.065
establishment of protein localization to membrane GO:0090150 121 0.061
regulation of proteolysis GO:0030162 293 0.059
mitochondrion organization GO:0007005 156 0.054
purine ribonucleoside metabolic process GO:0046128 437 0.053
regulation of cellular ketone metabolic process GO:0010565 50 0.052
cytoplasmic transport GO:0016482 379 0.051
cellular amine metabolic process GO:0044106 41 0.051
single organism cellular localization GO:1902580 332 0.051
innate immune response GO:0045087 178 0.048
regulation of cellular amino acid metabolic process GO:0006521 6 0.047
single organism membrane organization GO:0044802 268 0.045
nucleoside phosphate catabolic process GO:1901292 412 0.045
amine metabolic process GO:0009308 44 0.044
gtp metabolic process GO:0046039 239 0.043
protein localization to organelle GO:0033365 280 0.042
monocarboxylic acid metabolic process GO:0032787 185 0.042
regulation of cellular amine metabolic process GO:0033238 11 0.041
cellular amino acid metabolic process GO:0006520 116 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
protein localization to mitochondrion GO:0070585 25 0.038
immune response GO:0006955 307 0.038
protein targeting GO:0006605 187 0.038
positive regulation of hydrolase activity GO:0051345 331 0.037
ribonucleoside triphosphate catabolic process GO:0009203 391 0.036
single organism carbohydrate metabolic process GO:0044723 193 0.036
organophosphate catabolic process GO:0046434 430 0.034
negative regulation of programmed cell death GO:0043069 321 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.032
multicellular organismal aging GO:0010259 3 0.032
membrane organization GO:0061024 292 0.032
ribonucleoside catabolic process GO:0042454 406 0.032
negative regulation of cell death GO:0060548 345 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
posttranscriptional regulation of gene expression GO:0010608 213 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
steroid metabolic process GO:0008202 94 0.031
positive regulation of catabolic process GO:0009896 310 0.030
defense response GO:0006952 315 0.030
mitochondrial transport GO:0006839 60 0.029
purine containing compound catabolic process GO:0072523 411 0.029
regulation of nucleoside metabolic process GO:0009118 209 0.028
intracellular protein transmembrane import GO:0044743 23 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
peripheral nervous system development GO:0007422 2 0.027
positive regulation of apoptotic process GO:0043065 246 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
regulation of synaptic plasticity GO:0048167 3 0.027
protein oligomerization GO:0051259 173 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
nucleotide catabolic process GO:0009166 408 0.026
guanosine containing compound catabolic process GO:1901069 239 0.026
protein modification by small protein conjugation GO:0032446 342 0.026
positive regulation of phosphorylation GO:0042327 394 0.025
regulation of gtp catabolic process GO:0033124 180 0.025
guanosine containing compound metabolic process GO:1901068 244 0.025
mitochondrial membrane organization GO:0007006 40 0.025
regulation of nucleotide catabolic process GO:0030811 205 0.024
cellular protein complex assembly GO:0043623 188 0.024
locomotory behavior GO:0007626 1 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
nucleoside monophosphate catabolic process GO:0009125 159 0.024
purine nucleoside catabolic process GO:0006152 398 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
regulation of cell growth GO:0001558 135 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
regulation of protein localization GO:0032880 296 0.022
regulation of gtpase activity GO:0043087 180 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
actin filament based process GO:0030029 224 0.022
apoptotic signaling pathway GO:0097190 268 0.022
protein maturation GO:0051604 233 0.022
cellular lipid metabolic process GO:0044255 303 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
lipid biosynthetic process GO:0008610 177 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
positive regulation of transport GO:0051050 336 0.021
cellular component morphogenesis GO:0032989 314 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
intrinsic apoptotic signaling pathway GO:0097193 127 0.020
growth GO:0040007 202 0.020
cell growth GO:0016049 160 0.020
regulation of cell differentiation GO:0045595 393 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
protein homooligomerization GO:0051260 100 0.020
gtp catabolic process GO:0006184 237 0.020
inner mitochondrial membrane organization GO:0007007 8 0.020
regulation of intracellular transport GO:0032386 195 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
positive regulation of proteolysis GO:0045862 142 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
positive regulation of protein transport GO:0051222 135 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
response to wounding GO:0009611 168 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
response to cytokine GO:0034097 232 0.019
adult locomotory behavior GO:0008344 1 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
positive regulation of organelle organization GO:0010638 195 0.018
nucleoside catabolic process GO:0009164 408 0.018
ras protein signal transduction GO:0007265 73 0.018
protein ubiquitination GO:0016567 314 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
response to axon injury GO:0048678 1 0.018
protein targeting to mitochondrion GO:0006626 19 0.018
neuromuscular junction development GO:0007528 3 0.018
regulation of peptidase activity GO:0052547 180 0.018
positive regulation of cell death GO:0010942 263 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.017
regulation of secretion by cell GO:1903530 177 0.017
regulation of intracellular protein transport GO:0033157 123 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
regulation of protein kinase activity GO:0045859 289 0.017
regulation of kinase activity GO:0043549 314 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
vesicle mediated transport GO:0016192 371 0.017
rna processing GO:0006396 255 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.017
cell morphogenesis GO:0000902 296 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
regulation of protein transport GO:0051223 213 0.016
dephosphorylation GO:0016311 209 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
protein processing GO:0016485 226 0.016
female gamete generation GO:0007292 2 0.016
Worm
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
mitochondrial respiratory chain complex assembly GO:0033108 23 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
chromosome segregation GO:0007059 114 0.016
response to oxygen containing compound GO:1901700 369 0.016
regulation of protein stability GO:0031647 87 0.016
cellular response to cytokine stimulus GO:0071345 181 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
positive regulation of intracellular transport GO:0032388 104 0.015
neurogenesis GO:0022008 169 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.015
fatty acid metabolic process GO:0006631 115 0.015
protein import into mitochondrial inner membrane GO:0045039 3 0.015
regulation of secretion GO:0051046 194 0.015
oogenesis GO:0048477 2 0.015
Worm
protein catabolic process GO:0030163 325 0.015
positive regulation of protein complex assembly GO:0031334 86 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
dna repair GO:0006281 198 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
negative regulation of protein modification process GO:0031400 200 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
histone modification GO:0016570 251 0.014
cell projection organization GO:0030030 252 0.014
regulation of defense response GO:0031347 154 0.014
establishment of protein localization to mitochondrion GO:0072655 22 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
regulation of transferase activity GO:0051338 355 0.014
positive regulation of protein targeting to membrane GO:0090314 8 0.014
cell part morphogenesis GO:0032990 137 0.014
regulation of immune response GO:0050776 201 0.014
glycerophospholipid metabolic process GO:0006650 84 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
oxidation reduction process GO:0055114 396 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
response to external biotic stimulus GO:0043207 261 0.013
metencephalon development GO:0022037 2 0.013
regulation of protein processing GO:0070613 150 0.013
regulation of protein catabolic process GO:0042176 155 0.013
regulation of protein complex assembly GO:0043254 147 0.013
developmental programmed cell death GO:0010623 3 0.013
associative learning GO:0008306 1 0.013
intracellular protein transmembrane transport GO:0065002 24 0.013
plasma membrane organization GO:0007009 115 0.013
metal ion homeostasis GO:0055065 169 0.013
regulation of cell motility GO:2000145 299 0.013
covalent chromatin modification GO:0016569 254 0.013
response to nitrogen compound GO:1901698 184 0.013
response to biotic stimulus GO:0009607 276 0.013
regeneration GO:0031099 4 0.013
determination of adult lifespan GO:0008340 2 0.013
positive regulation of immune system process GO:0002684 283 0.012
glycolipid biosynthetic process GO:0009247 12 0.012
regulation of cell cycle GO:0051726 393 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
nerve development GO:0021675 4 0.012
positive regulation of developmental process GO:0051094 314 0.012
generation of neurons GO:0048699 152 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
cytokine production GO:0001816 247 0.012
regulation of dna metabolic process GO:0051052 153 0.012
protein import GO:0017038 130 0.012
positive regulation of cytoskeleton organization GO:0051495 83 0.012
regulation of response to external stimulus GO:0032101 222 0.012
sensory perception of pain GO:0019233 4 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.012
cell cell signaling GO:0007267 155 0.012
cranial nerve morphogenesis GO:0021602 1 0.012
visual learning GO:0008542 1 0.012
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.012
negative regulation of developmental process GO:0051093 247 0.012
rho protein signal transduction GO:0007266 26 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
positive regulation of protein catabolic process GO:0045732 75 0.012
phospholipid metabolic process GO:0006644 99 0.012
cofactor metabolic process GO:0051186 87 0.012
positive regulation of intracellular protein transport GO:0090316 76 0.012
regulation of hormone levels GO:0010817 125 0.012
negative regulation of immune system process GO:0002683 136 0.012
motor neuron axon guidance GO:0008045 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
transmembrane transport GO:0055085 399 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.011
cell cycle phase transition GO:0044770 173 0.011
gpi anchor metabolic process GO:0006505 11 0.011
biological adhesion GO:0022610 331 0.011
membrane lipid metabolic process GO:0006643 53 0.011
dna catabolic process GO:0006308 49 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
positive regulation of cytokine production GO:0001819 167 0.011
regulation of cell development GO:0060284 161 0.011
regulation of protein targeting GO:1903533 91 0.011
positive regulation of peptidase activity GO:0010952 88 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
chromatin modification GO:0016568 298 0.010
secretion GO:0046903 254 0.010
regulation of cellular component movement GO:0051270 334 0.010
nervous system development GO:0007399 293 0.010
cellular chemical homeostasis GO:0055082 180 0.010
negative regulation of protein maturation GO:1903318 142 0.010
positive regulation of kinase activity GO:0033674 204 0.010
chromatin organization GO:0006325 351 0.010
carbohydrate derivative biosynthetic process GO:1901137 207 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
spermatid differentiation GO:0048515 4 0.010
positive regulation of nucleotide metabolic process GO:0045981 230 0.010
regulation of cell cycle process GO:0010564 266 0.010
rna interference GO:0016246 4 0.010
hippocampus development GO:0021766 1 0.010
limbic system development GO:0021761 3 0.010
cell activation GO:0001775 213 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
negative regulation of protein processing GO:0010955 142 0.010
response to drug GO:0042493 81 0.010
negative regulation of proteolysis GO:0045861 132 0.010

PMVK disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.456
inherited metabolic disorder DOID:655 242 0.456
carbohydrate metabolic disorder DOID:2978 55 0.239
congenital disorder of glycosylation DOID:5212 26 0.239
disease of cellular proliferation DOID:14566 174 0.059
cancer DOID:162 167 0.047
organ system cancer DOID:0050686 164 0.047
endocrine gland cancer DOID:170 26 0.030
congenital disorder of glycosylation type i DOID:0050570 16 0.021
central nervous system disease DOID:331 186 0.015
neurodegenerative disease DOID:1289 102 0.015
nervous system disease DOID:863 431 0.015
disease of mental health DOID:150 70 0.012
sensory system disease DOID:0050155 203 0.012
eye and adnexa disease DOID:1492 150 0.012
gastrointestinal system cancer DOID:3119 52 0.011
amino acid metabolic disorder DOID:9252 50 0.010