Homo sapiens

7 known processes

LYPLA1

lysophospholipase I

(Aliases: APT-1,LYSOPLA,LPL1,hAPT1)

LYPLA1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate biosynthetic process GO:0090407 163 0.416
nucleotide biosynthetic process GO:0009165 109 0.359
carbohydrate metabolic process GO:0005975 207 0.342
organic hydroxy compound metabolic process GO:1901615 147 0.329
oxidation reduction process GO:0055114 396 0.329
cellular lipid metabolic process GO:0044255 303 0.304
nucleoside phosphate biosynthetic process GO:1901293 109 0.262
small molecule biosynthetic process GO:0044283 157 0.209
single organism membrane organization GO:0044802 268 0.181
membrane organization GO:0061024 292 0.136
negative regulation of apoptotic process GO:0043066 316 0.128
purine nucleotide biosynthetic process GO:0006164 84 0.101
organonitrogen compound biosynthetic process GO:1901566 200 0.093
negative regulation of phosphate metabolic process GO:0045936 267 0.087
negative regulation of programmed cell death GO:0043069 321 0.080
lipid biosynthetic process GO:0008610 177 0.077
purine nucleoside triphosphate metabolic process GO:0009144 412 0.077
glycerolipid biosynthetic process GO:0045017 51 0.077
single organism carbohydrate metabolic process GO:0044723 193 0.073
purine nucleoside monophosphate metabolic process GO:0009126 186 0.071
carbohydrate derivative biosynthetic process GO:1901137 207 0.070
ribose phosphate biosynthetic process GO:0046390 82 0.068
signal transduction by phosphorylation GO:0023014 297 0.067
ribonucleoside monophosphate metabolic process GO:0009161 187 0.064
nitrogen compound transport GO:0071705 191 0.063
protein glycosylation GO:0006486 62 0.062
phospholipid metabolic process GO:0006644 99 0.061
protein localization to membrane GO:0072657 160 0.058
vesicle mediated transport GO:0016192 371 0.058
negative regulation of phosphorus metabolic process GO:0010563 267 0.056
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.056
atp metabolic process GO:0046034 176 0.055
ribonucleotide biosynthetic process GO:0009260 81 0.055
amine metabolic process GO:0009308 44 0.053
endomembrane system organization GO:0010256 196 0.053
secretion GO:0046903 254 0.053
purine containing compound biosynthetic process GO:0072522 88 0.049
mitotic cell cycle GO:0000278 326 0.049
alcohol metabolic process GO:0006066 114 0.048
glycerolipid metabolic process GO:0046486 107 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.047
ribonucleoside catabolic process GO:0042454 406 0.046
positive regulation of cellular catabolic process GO:0031331 284 0.045
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.043
phospholipid biosynthetic process GO:0008654 44 0.041
blood vessel development GO:0001568 172 0.040
single organism cell adhesion GO:0098602 179 0.039
purine ribonucleotide biosynthetic process GO:0009152 79 0.039
negative regulation of cell death GO:0060548 345 0.035
transmembrane transport GO:0055085 399 0.035
protein catabolic process GO:0030163 325 0.035
glycerophospholipid metabolic process GO:0006650 84 0.035
anatomical structure formation involved in morphogenesis GO:0048646 284 0.035
multicellular organismal aging GO:0010259 3 0.035
polysaccharide metabolic process GO:0005976 33 0.035
ribonucleoside triphosphate metabolic process GO:0009199 412 0.034
ion transmembrane transport GO:0034220 338 0.033
nucleoside monophosphate metabolic process GO:0009123 191 0.032
morphogenesis of embryonic epithelium GO:0016331 4 0.030
response to external biotic stimulus GO:0043207 261 0.030
regulation of transferase activity GO:0051338 355 0.030
negative regulation of phosphorylation GO:0042326 174 0.029
ribonucleoside biosynthetic process GO:0042455 25 0.029
oocyte differentiation GO:0009994 2 0.029
regulation of proteolysis GO:0030162 293 0.028
determination of adult lifespan GO:0008340 2 0.028
lipid metabolic process GO:0006629 381 0.028
regulation of cell development GO:0060284 161 0.028
protein o linked glycosylation GO:0006493 21 0.027
inorganic cation transmembrane transport GO:0098662 194 0.027
nucleoside triphosphate metabolic process GO:0009141 422 0.027
cellular component morphogenesis GO:0032989 314 0.027
response to oxidative stress GO:0006979 121 0.027
cellular ketone metabolic process GO:0042180 80 0.026
positive regulation of proteolysis GO:0045862 142 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
negative regulation of transferase activity GO:0051348 124 0.025
regulation of cell cycle GO:0051726 393 0.025
cell type specific apoptotic process GO:0097285 125 0.025
actin filament based process GO:0030029 224 0.024
immune response GO:0006955 307 0.024
neuromuscular junction development GO:0007528 3 0.024
negative regulation of cellular amine metabolic process GO:0033239 3 0.023
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.023
purine containing compound catabolic process GO:0072523 411 0.023
plasma membrane organization GO:0007009 115 0.022
positive regulation of cell cycle GO:0045787 140 0.022
macromolecule methylation GO:0043414 97 0.022
mapk cascade GO:0000165 288 0.022
methylation GO:0032259 106 0.022
cell morphogenesis GO:0000902 296 0.022
response to other organism GO:0051707 261 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.021
embryo development GO:0009790 123 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.020
positive regulation of developmental process GO:0051094 314 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
glycoprotein metabolic process GO:0009100 110 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
generation of neurons GO:0048699 152 0.020
dephosphorylation GO:0016311 209 0.020
energy derivation by oxidation of organic compounds GO:0015980 43 0.020
regulation of anatomical structure size GO:0090066 101 0.019
cellular protein complex assembly GO:0043623 188 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
generation of precursor metabolites and energy GO:0006091 68 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
positive regulation of cell differentiation GO:0045597 211 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
response to lipid GO:0033993 206 0.018
purine containing compound salvage GO:0043101 2 0.018
regulation of proteasomal protein catabolic process GO:0061136 87 0.018
barbed end actin filament capping GO:0051016 3 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
cation transmembrane transport GO:0098655 238 0.017
apoptotic signaling pathway GO:0097190 268 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
glycerophospholipid biosynthetic process GO:0046474 40 0.017
neuron development GO:0048666 113 0.017
striated muscle myosin thick filament assembly GO:0071688 2 0.016
segmentation GO:0035282 4 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
anion transport GO:0006820 161 0.016
positive regulation of meiotic cell cycle GO:0051446 2 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.016
cellular protein catabolic process GO:0044257 261 0.016
glycosyl compound biosynthetic process GO:1901659 27 0.016
regulation of actin filament based process GO:0032970 141 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.016
positive regulation of catabolic process GO:0009896 310 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
cellular response to lipid GO:0071396 127 0.016
regulation of growth GO:0040008 165 0.015
protein kinase b signaling GO:0043491 69 0.015
leukocyte activation GO:0045321 164 0.015
post embryonic development GO:0009791 2 0.015
regulation of autophagy GO:0010506 52 0.015
neuron death GO:0070997 65 0.015
cellular amine metabolic process GO:0044106 41 0.015
secretion by cell GO:0032940 226 0.015
autophagy GO:0006914 88 0.015
response to biotic stimulus GO:0009607 276 0.015
actin cytoskeleton organization GO:0030036 207 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
cell projection organization GO:0030030 252 0.015
mitochondrial membrane organization GO:0007006 40 0.015
response to molecule of bacterial origin GO:0002237 82 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
protein alkylation GO:0008213 74 0.014
hindbrain development GO:0030902 3 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
regulation of protein catabolic process GO:0042176 155 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
regulation of cell adhesion GO:0030155 166 0.014
response to abiotic stimulus GO:0009628 336 0.014
cytoplasmic transport GO:0016482 379 0.014
rna export from nucleus GO:0006405 33 0.014
alcohol biosynthetic process GO:0046165 52 0.014
glycoprotein biosynthetic process GO:0009101 91 0.013
nucleoside monophosphate biosynthetic process GO:0009124 19 0.013
nucleoside triphosphate biosynthetic process GO:0009142 20 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
cellular amino acid metabolic process GO:0006520 116 0.013
endocytosis GO:0006897 159 0.013
regulation of neuron death GO:1901214 56 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
blood vessel morphogenesis GO:0048514 162 0.013
vasculature development GO:0001944 181 0.013
dolichol metabolic process GO:0019348 3 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
biological adhesion GO:0022610 331 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
meiotic chromosome segregation GO:0045132 4 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
negative regulation of neuron apoptotic process GO:0043524 23 0.012
organelle fission GO:0048285 149 0.012
regulation of cell cycle process GO:0010564 266 0.012
cell projection morphogenesis GO:0048858 129 0.012
organic acid biosynthetic process GO:0016053 97 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
nuclear transport GO:0051169 179 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
purine nucleoside monophosphate biosynthetic process GO:0009127 16 0.012
organophosphate catabolic process GO:0046434 430 0.011
positive regulation of organelle organization GO:0010638 195 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.011
regulation of actin filament length GO:0030832 56 0.011
multi organism cellular process GO:0044764 156 0.011
hexose metabolic process GO:0019318 55 0.011
jnk cascade GO:0007254 80 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.011
innate immune response GO:0045087 178 0.011
neuron projection development GO:0031175 106 0.011
regulation of protein kinase b signaling GO:0051896 61 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
regulation of protein localization GO:0032880 296 0.011
regeneration GO:0031099 4 0.011
regulation of vasculature development GO:1901342 97 0.011
regulation of cellular component movement GO:0051270 334 0.011
regulation of cell projection organization GO:0031344 107 0.010
nucleoside biosynthetic process GO:0009163 26 0.010
actin filament polymerization GO:0030041 45 0.010
cellular response to hormone stimulus GO:0032870 125 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
regulation of cell migration GO:0030334 289 0.010
negative regulation of protein complex disassembly GO:0043242 20 0.010
ribonucleoside monophosphate biosynthetic process GO:0009156 17 0.010

LYPLA1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.306
inherited metabolic disorder DOID:655 242 0.306
amino acid metabolic disorder DOID:9252 50 0.209
disease of mental health DOID:150 70 0.018
developmental disorder of mental health DOID:0060037 29 0.018
immune system disease DOID:2914 155 0.017
hematopoietic system disease DOID:74 100 0.017
disease of cellular proliferation DOID:14566 174 0.013