Homo sapiens

197 known processes

PLEK

pleckstrin

(Aliases: FLJ27168,P47)

PLEK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macrophage chemotaxis GO:0010759 3 0.842
cytokine production GO:0001816 247 0.799
cellular amine metabolic process GO:0044106 41 0.691
response to external biotic stimulus GO:0043207 261 0.683
response to biotic stimulus GO:0009607 276 0.648
defense response GO:0006952 315 0.561
metal ion homeostasis GO:0055065 169 0.554
regulation of cellular amino acid metabolic process GO:0006521 6 0.542
granulocyte migration GO:0097530 40 0.539
leukocyte activation GO:0045321 164 0.538
positive regulation of immune system process GO:0002684 283 0.532
response to other organism GO:0051707 261 0.521
cellular response to oxygen containing compound GO:1901701 276 0.510
amine metabolic process GO:0009308 44 0.509
immune response GO:0006955 307 0.496
coagulation GO:0050817 78 0.452
positive regulation of acute inflammatory response GO:0002675 2 0.446
regulation of neutrophil chemotaxis GO:0090022 10 0.445
regulation of leukocyte migration GO:0002685 63 0.439
cellular divalent inorganic cation homeostasis GO:0072503 128 0.428
cellular amino acid metabolic process GO:0006520 116 0.425
cell chemotaxis GO:0060326 112 0.410
taxis GO:0042330 157 0.397
regulation of defense response GO:0031347 154 0.395
leukocyte migration GO:0050900 107 0.392
response to nitric oxide GO:0071731 4 0.392
myeloid leukocyte migration GO:0097529 62 0.385
negative regulation of cell proliferation GO:0008285 228 0.385
regulation of cellular ketone metabolic process GO:0010565 50 0.377
regulation of cytokine production GO:0001817 232 0.351
defense response to other organism GO:0098542 129 0.343
cation transport GO:0006812 331 0.337
granulocyte chemotaxis GO:0071621 37 0.336
myeloid cell differentiation GO:0030099 117 0.336
positive regulation of immune response GO:0050778 159 0.334
regulation of macrophage chemotaxis GO:0010758 4 0.330
neutrophil chemotaxis GO:0030593 24 0.326
positive regulation of leukocyte chemotaxis GO:0002690 38 0.302
second messenger mediated signaling GO:0019932 78 0.299
regulation of cell activation GO:0050865 125 0.288
Mouse
hemopoiesis GO:0030097 180 0.275
cellular calcium ion homeostasis GO:0006874 117 0.269
cation homeostasis GO:0055080 189 0.265
positive regulation of cytokine production GO:0001819 167 0.257
response to oxygen containing compound GO:1901700 369 0.255
neutrophil migration GO:1990266 25 0.255
positive regulation of cellular component movement GO:0051272 181 0.253
regulation of homeostatic process GO:0032844 121 0.253
response to bacterium GO:0009617 144 0.252
positive regulation of neutrophil chemotaxis GO:0090023 7 0.247
positive regulation of neutrophil migration GO:1902624 7 0.246
immune system development GO:0002520 195 0.245
positive regulation of cell migration GO:0030335 172 0.241
negative regulation of programmed cell death GO:0043069 321 0.240
positive regulation of transport GO:0051050 336 0.237
cellular response to endogenous stimulus GO:0071495 336 0.234
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.233
cell activation GO:0001775 213 0.229
vesicle mediated transport GO:0016192 371 0.229
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.225
positive regulation of leukocyte migration GO:0002687 46 0.225
regulation of protein serine threonine kinase activity GO:0071900 179 0.221
chemotaxis GO:0006935 157 0.218
positive regulation of cell differentiation GO:0045597 211 0.217
lymphocyte activation GO:0046649 133 0.217
positive regulation of developmental process GO:0051094 314 0.215
regulation of cell migration GO:0030334 289 0.213
positive regulation of chemotaxis GO:0050921 57 0.213
cytosolic calcium ion homeostasis GO:0051480 89 0.210
hemostasis GO:0007599 76 0.203
cellular response to molecule of bacterial origin GO:0071219 62 0.202
cellular ketone metabolic process GO:0042180 80 0.201
nitrogen compound transport GO:0071705 191 0.199
regulation of leukocyte proliferation GO:0070663 67 0.198
cytokine mediated signaling pathway GO:0019221 109 0.197
cellular homeostasis GO:0019725 196 0.194
positive regulation of response to external stimulus GO:0032103 88 0.188
positive regulation of cellular amine metabolic process GO:0033240 7 0.187
cell adhesion GO:0007155 325 0.187
regulation of locomotion GO:0040012 329 0.184
mapk cascade GO:0000165 288 0.183
leukocyte chemotaxis GO:0030595 76 0.181
regulation of response to external stimulus GO:0032101 222 0.178
Mouse
positive regulation of behavior GO:0048520 60 0.177
biological adhesion GO:0022610 331 0.175
positive regulation of transferase activity GO:0051347 227 0.175
regulation of neutrophil migration GO:1902622 10 0.174
chemical homeostasis GO:0048878 306 0.173
regulation of cellular amine metabolic process GO:0033238 11 0.168
positive regulation of map kinase activity GO:0043406 80 0.167
cellular ion homeostasis GO:0006873 168 0.166
negative regulation of multicellular organismal process GO:0051241 317 0.158
negative regulation of alpha beta t cell activation GO:0046636 3 0.156
regulation of kinase activity GO:0043549 314 0.156
regulation of tumor necrosis factor production GO:0032680 43 0.155
cellular chemical homeostasis GO:0055082 180 0.152
positive regulation of programmed cell death GO:0043068 249 0.148
regulation of protein transport GO:0051223 213 0.147
positive regulation of mapk cascade GO:0043410 190 0.143
regulation of vesicle mediated transport GO:0060627 130 0.143
female gamete generation GO:0007292 2 0.140
regulation of establishment of protein localization GO:0070201 242 0.140
cellular response to lipid GO:0071396 127 0.140
negative regulation of apoptotic process GO:0043066 316 0.137
regulation of cell cycle GO:0051726 393 0.136
negative regulation of immune system process GO:0002683 136 0.136
regulation of mononuclear cell proliferation GO:0032944 65 0.135
ion homeostasis GO:0050801 230 0.132
g protein coupled receptor signaling pathway GO:0007186 207 0.131
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.131
positive regulation of stress activated mapk cascade GO:0032874 60 0.130
regulation of cell motility GO:2000145 299 0.128
positive regulation of cell proliferation GO:0008284 301 0.127
response to molecule of bacterial origin GO:0002237 82 0.126
peptidyl tyrosine modification GO:0018212 170 0.126
regulation of leukocyte chemotaxis GO:0002688 46 0.125
eosinophil activation involved in immune response GO:0002278 2 0.125
cellular cation homeostasis GO:0030003 163 0.124
cellular response to biotic stimulus GO:0071216 71 0.124
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.122
regulation of mapk cascade GO:0043408 262 0.122
antigen processing and presentation GO:0019882 33 0.121
positive regulation of locomotion GO:0040017 186 0.119
mature natural killer cell chemotaxis GO:0035782 1 0.118
regulation of ion transport GO:0043269 189 0.117
sequestering of metal ion GO:0051238 24 0.117
positive regulation of cellular component organization GO:0051130 376 0.116
ras protein signal transduction GO:0007265 73 0.116
apoptotic signaling pathway GO:0097190 268 0.115
regulation of protein localization GO:0032880 296 0.115
cellular metal ion homeostasis GO:0006875 146 0.114
regulation of intracellular transport GO:0032386 195 0.113
negative regulation of protein metabolic process GO:0051248 391 0.112
regulation of immune response GO:0050776 201 0.112
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.111
leukocyte proliferation GO:0070661 74 0.111
regulation of lymphocyte activation GO:0051249 103 0.110
regulation of nucleotide metabolic process GO:0006140 269 0.110
regulation of cellular component movement GO:0051270 334 0.109
positive regulation of nucleotide metabolic process GO:0045981 230 0.108
phosphatidylinositol mediated signaling GO:0048015 55 0.108
regulation of apoptotic signaling pathway GO:2001233 175 0.107
regulation of endocytosis GO:0030100 72 0.106
nucleotide catabolic process GO:0009166 408 0.106
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.105
guanosine containing compound metabolic process GO:1901068 244 0.105
calcium ion homeostasis GO:0055074 122 0.105
ribonucleoside catabolic process GO:0042454 406 0.103
innate immune response GO:0045087 178 0.103
cell activation involved in immune response GO:0002263 30 0.103
myeloid leukocyte activation GO:0002274 34 0.102
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.101
cell type specific apoptotic process GO:0097285 125 0.100
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.100
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.099
immune effector process GO:0002252 159 0.099
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.098
adaptive immune response GO:0002250 49 0.098
response to wounding GO:0009611 168 0.098
protein oligomerization GO:0051259 173 0.098
hematopoietic or lymphoid organ development GO:0048534 186 0.097
positive regulation of cell adhesion GO:0045785 84 0.097
divalent inorganic cation homeostasis GO:0072507 136 0.096
negative regulation of cell death GO:0060548 345 0.096
positive regulation of lymphocyte proliferation GO:0050671 46 0.095
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.094
positive regulation of cell motility GO:2000147 177 0.094
signal transduction by phosphorylation GO:0023014 297 0.093
sensory perception of pain GO:0019233 4 0.093
divalent metal ion transport GO:0070838 152 0.093
regulation of body fluid levels GO:0050878 99 0.092
endomembrane system organization GO:0010256 196 0.092
small gtpase mediated signal transduction GO:0007264 78 0.092
negative regulation of apoptotic signaling pathway GO:2001234 97 0.090
cyclic nucleotide metabolic process GO:0009187 82 0.090
stress activated protein kinase signaling cascade GO:0031098 94 0.089
regulation of myeloid cell differentiation GO:0045637 81 0.089
negative regulation of t cell cytokine production GO:0002725 4 0.089
anatomical structure formation involved in morphogenesis GO:0048646 284 0.088
response to organonitrogen compound GO:0010243 156 0.088
wound healing GO:0042060 115 0.088
regulation of chemotaxis GO:0050920 74 0.088
secretion by cell GO:0032940 226 0.088
positive regulation of protein kinase activity GO:0045860 190 0.088
interleukin 10 production GO:0032613 17 0.087
regulation of cytokine secretion GO:0050707 57 0.087
positive regulation of gtpase activity GO:0043547 166 0.087
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.087
cellular response to cytokine stimulus GO:0071345 181 0.087
glycosyl compound catabolic process GO:1901658 413 0.086
purine ribonucleotide catabolic process GO:0009154 404 0.086
purine ribonucleoside catabolic process GO:0046130 398 0.086
positive regulation of defense response GO:0031349 87 0.086
chronic inflammatory response GO:0002544 2 0.085
positive regulation of cell death GO:0010942 263 0.085
tumor necrosis factor production GO:0032640 43 0.085
divalent inorganic cation transport GO:0072511 158 0.084
negative regulation of cellular amine metabolic process GO:0033239 3 0.083
positive regulation of jnk cascade GO:0046330 52 0.083
positive regulation of cellular catabolic process GO:0031331 284 0.083
system process GO:0003008 349 0.082
positive regulation of catabolic process GO:0009896 310 0.082
regulation of transferase activity GO:0051338 355 0.080
regulation of leukocyte activation GO:0002694 115 0.080
regulation of granulocyte chemotaxis GO:0071622 16 0.080
regulation of cell adhesion GO:0030155 166 0.080
regulation of protein kinase activity GO:0045859 289 0.079
cellular response to lipopolysaccharide GO:0071222 57 0.078
extrinsic apoptotic signaling pathway GO:0097191 119 0.077
single organismal cell cell adhesion GO:0016337 148 0.077
regulation of gtpase activity GO:0043087 180 0.077
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.077
calcium mediated signaling GO:0019722 44 0.076
endocytosis GO:0006897 159 0.076
heterotypic cell cell adhesion GO:0034113 28 0.076
positive regulation of phosphorylation GO:0042327 394 0.076
response to lipid GO:0033993 206 0.075
positive regulation of rho gtpase activity GO:0032321 56 0.075
regulation of purine nucleotide catabolic process GO:0033121 205 0.075
regulation of cell cell adhesion GO:0022407 57 0.075
enzyme linked receptor protein signaling pathway GO:0007167 303 0.075
regulation of protein targeting GO:1903533 91 0.075
negative regulation of cytokine production GO:0001818 82 0.075
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 8 0.074
regulation of nucleoside metabolic process GO:0009118 209 0.074
regulation of cellular component biogenesis GO:0044087 281 0.073
positive regulation of hydrolase activity GO:0051345 331 0.073
regulation of rho protein signal transduction GO:0035023 79 0.073
leukocyte differentiation GO:0002521 98 0.072
positive regulation of apoptotic process GO:0043065 246 0.072
metal ion transport GO:0030001 272 0.072
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.071
intracellular protein transport GO:0006886 270 0.071
regulation of cellular response to stress GO:0080135 244 0.070
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.070
regulation of lymphocyte proliferation GO:0050670 64 0.070
regulation of purine nucleotide metabolic process GO:1900542 264 0.069
lymphocyte mediated immunity GO:0002449 48 0.068
maintenance of location GO:0051235 112 0.068
single organism cell adhesion GO:0098602 179 0.068
regulation of anatomical structure morphogenesis GO:0022603 286 0.068
multicellular organismal aging GO:0010259 3 0.067
negative regulation of homeostatic process GO:0032845 59 0.067
positive regulation of granulocyte chemotaxis GO:0071624 9 0.066
positive regulation of immune effector process GO:0002699 40 0.066
negative regulation of cellular protein metabolic process GO:0032269 353 0.065
response to nitrogen compound GO:1901698 184 0.064
regulation of calcium ion transport into cytosol GO:0010522 33 0.064
purine nucleoside triphosphate metabolic process GO:0009144 412 0.064
regulation of ion homeostasis GO:2000021 73 0.063
lipid metabolic process GO:0006629 381 0.063
purine nucleoside triphosphate catabolic process GO:0009146 392 0.063
negative regulation of leukocyte apoptotic process GO:2000107 16 0.062
secretion GO:0046903 254 0.062
positive regulation of homeostatic process GO:0032846 47 0.062
ribonucleoside triphosphate metabolic process GO:0009199 412 0.062
regulation of actin filament based process GO:0032970 141 0.061
positive regulation of protein phosphorylation GO:0001934 313 0.061
transmembrane transport GO:0055085 399 0.061
response to lipopolysaccharide GO:0032496 70 0.061
positive regulation of leukocyte activation GO:0002696 80 0.060
gtp metabolic process GO:0046039 239 0.060
regulation of cell differentiation GO:0045595 393 0.059
cardiovascular system development GO:0072358 262 0.059
positive regulation of response to wounding GO:1903036 28 0.059
Mouse
memory GO:0007613 3 0.058
positive regulation of leukocyte differentiation GO:1902107 37 0.058
mononuclear cell proliferation GO:0032943 71 0.058
positive regulation of kinase activity GO:0033674 204 0.058
immune response activating signal transduction GO:0002757 90 0.057
positive regulation of intracellular transport GO:0032388 104 0.056
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.056
negative regulation of catalytic activity GO:0043086 335 0.056
t cell activation GO:0042110 99 0.056
cytosolic calcium ion transport GO:0060401 48 0.056
regulation of secretion by cell GO:1903530 177 0.055
regulation of secretion GO:0051046 194 0.055
regulation of metal ion transport GO:0010959 120 0.055
single organism cellular localization GO:1902580 332 0.055
negative regulation of ion transport GO:0043271 39 0.054
anion transport GO:0006820 161 0.054
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.054
regulation of calcium ion transport GO:0051924 79 0.054
negative regulation of protein phosphorylation GO:0001933 140 0.053
purine ribonucleoside metabolic process GO:0046128 437 0.053
response to organic cyclic compound GO:0014070 204 0.053
regulation of leukocyte apoptotic process GO:2000106 25 0.053
regulation of multi organism process GO:0043900 157 0.053
regulation of protein secretion GO:0050708 86 0.052
positive regulation of t cell proliferation GO:0042102 33 0.052
cell morphogenesis GO:0000902 296 0.052
sequestering of calcium ion GO:0051208 17 0.052
regulation of proteolysis GO:0030162 293 0.052
protein localization to organelle GO:0033365 280 0.052
rho protein signal transduction GO:0007266 26 0.052
peptide transport GO:0015833 74 0.051
serotonin transport GO:0006837 3 0.051
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.051
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.051
glial cell migration GO:0008347 4 0.050
regulation of angiogenesis GO:0045765 92 0.050
response to cytokine GO:0034097 232 0.050
regulation of gtp catabolic process GO:0033124 180 0.050
regulation of endothelial cell migration GO:0010594 67 0.050
inositol lipid mediated signaling GO:0048017 55 0.050
protein targeting GO:0006605 187 0.050
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.049
positive regulation of tumor necrosis factor production GO:0032760 21 0.049
calcium ion transport GO:0006816 147 0.049
blood vessel morphogenesis GO:0048514 162 0.049
regulation of stress activated mapk cascade GO:0032872 84 0.049
regulation of behavior GO:0050795 82 0.049
negative regulation of developmental process GO:0051093 247 0.048
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.048
response to diacyl bacterial lipopeptide GO:0071724 2 0.048
cyclic nucleotide mediated signaling GO:0019935 26 0.047
ribonucleotide catabolic process GO:0009261 405 0.047
gtp catabolic process GO:0006184 237 0.047
response to interleukin 1 GO:0070555 47 0.047
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.046
post embryonic development GO:0009791 2 0.046
regulation of myeloid leukocyte differentiation GO:0002761 39 0.045
cytoplasmic transport GO:0016482 379 0.045
regulation of nucleotide catabolic process GO:0030811 205 0.045
t cell differentiation GO:0030217 29 0.045
defense response to virus GO:0051607 71 0.045
neurological system process GO:0050877 163 0.045
leukocyte mediated immunity GO:0002443 59 0.045
oogenesis GO:0048477 2 0.044
production of molecular mediator of immune response GO:0002440 37 0.044
positive regulation of cell activation GO:0050867 81 0.043
Mouse
segmentation GO:0035282 4 0.043
macrophage chemotaxis GO:0048246 10 0.043
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.043
guanosine containing compound catabolic process GO:1901069 239 0.043
negative regulation of immune response GO:0050777 40 0.042
monocyte aggregation GO:0070487 4 0.042
regulation of lymphocyte mediated immunity GO:0002706 33 0.042
lipid localization GO:0010876 106 0.041
lymphocyte proliferation GO:0046651 70 0.041
cellular response to organic cyclic compound GO:0071407 127 0.041
negative regulation of cell differentiation GO:0045596 171 0.041
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.041
determination of adult lifespan GO:0008340 2 0.041
regulation of erk1 and erk2 cascade GO:0070372 99 0.040
immune response regulating signaling pathway GO:0002764 97 0.040
activation of mapk activity GO:0000187 45 0.040
purine nucleoside catabolic process GO:0006152 398 0.040
amide transport GO:0042886 76 0.040
protein kinase b signaling GO:0043491 69 0.040
regulation of protein processing GO:0070613 150 0.039
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.039
response to abiotic stimulus GO:0009628 336 0.039
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.038
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.038
purine containing compound catabolic process GO:0072523 411 0.038
positive regulation of production of molecular mediator of immune response GO:0002702 11 0.038
reactive oxygen species metabolic process GO:0072593 75 0.038
negative regulation of protein processing GO:0010955 142 0.037
cellular response to nitrogen compound GO:1901699 144 0.037
lipid biosynthetic process GO:0008610 177 0.037
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
regulation of jnk cascade GO:0046328 73 0.037
organic anion transport GO:0015711 103 0.037
acute inflammatory response GO:0002526 21 0.037
regulation of cytokine production involved in immune response GO:0002718 22 0.037
lymphocyte activation involved in immune response GO:0002285 20 0.037
regulation of innate immune response GO:0045088 97 0.037
response to metal ion GO:0010038 84 0.037
regulation of rho gtpase activity GO:0032319 66 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
negative regulation of protein modification process GO:0031400 200 0.036
positive regulation of ras gtpase activity GO:0032320 117 0.036
erk1 and erk2 cascade GO:0070371 104 0.036
positive regulation of protein transport GO:0051222 135 0.036
circulatory system development GO:0072359 262 0.035
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.035
positive regulation of leukocyte proliferation GO:0070665 48 0.035
leukocyte apoptotic process GO:0071887 31 0.035
activation of immune response GO:0002253 114 0.035
regulation of peptide transport GO:0090087 62 0.035
cellular response to growth factor stimulus GO:0071363 197 0.035
response to interferon gamma GO:0034341 39 0.034
regulation of tumor necrosis factor biosynthetic process GO:0042534 8 0.034
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.034
negative regulation of cellular component organization GO:0051129 235 0.034
regulation of leukocyte mediated immunity GO:0002703 38 0.034
positive regulation of nucleoside metabolic process GO:0045979 186 0.033
tyrosine phosphorylation of stat protein GO:0007260 33 0.033
regulation of cell division GO:0051302 116 0.033
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.033
response to inorganic substance GO:0010035 127 0.033
peptide hormone secretion GO:0030072 50 0.033
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.033
regulation of immune effector process GO:0002697 91 0.033
single organism membrane organization GO:0044802 268 0.033
cellular response to triacyl bacterial lipopeptide GO:0071727 2 0.033
regulation of protein localization to nucleus GO:1900180 85 0.033
response to growth factor GO:0070848 205 0.033
mitotic cell cycle process GO:1903047 286 0.032
cellular component morphogenesis GO:0032989 314 0.032
response to hormone GO:0009725 175 0.032
regulation of lipid metabolic process GO:0019216 96 0.032
positive regulation of t cell activation GO:0050870 54 0.032
myeloid leukocyte differentiation GO:0002573 60 0.032
negative regulation of myeloid cell differentiation GO:0045638 42 0.032
negative regulation of intracellular signal transduction GO:1902532 183 0.032
negative regulation of sequestering of calcium ion GO:0051283 41 0.032
peptidyl tyrosine phosphorylation GO:0018108 170 0.032
response to alcohol GO:0097305 64 0.032
negative regulation of leukocyte mediated immunity GO:0002704 14 0.031
positive regulation of ion transport GO:0043270 87 0.031
carboxylic acid transport GO:0046942 63 0.031
phospholipid metabolic process GO:0006644 99 0.031
regulation of blood coagulation GO:0030193 42 0.031
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.031
vasculature development GO:0001944 181 0.031
homotypic cell cell adhesion GO:0034109 47 0.031
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.031
regulation of cell adhesion mediated by integrin GO:0033628 22 0.031
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.031
leukocyte activation involved in immune response GO:0002366 30 0.031
nuclear import GO:0051170 106 0.031
t helper 1 cell activation GO:0035711 1 0.031
establishment of protein localization to organelle GO:0072594 172 0.030
regulation of system process GO:0044057 101 0.030
regulation of cell cycle process GO:0010564 266 0.030
regulation of transmembrane transport GO:0034762 139 0.030
positive regulation of cell cell adhesion GO:0022409 22 0.030
negative regulation of immune effector process GO:0002698 38 0.030
negative regulation of hydrolase activity GO:0051346 182 0.030
cytokine production involved in immune response GO:0002367 27 0.030
cellular response to dna damage stimulus GO:0006974 379 0.030
ion transmembrane transport GO:0034220 338 0.029
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.029
cell adhesion mediated by integrin GO:0033627 27 0.029
blood coagulation GO:0007596 76 0.029
cellular lipid metabolic process GO:0044255 303 0.029
nervous system development GO:0007399 293 0.029
behavior GO:0007610 112 0.029
regulation of production of molecular mediator of immune response GO:0002700 25 0.029
jak stat cascade GO:0007259 46 0.029
oxidation reduction process GO:0055114 396 0.029
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.029
regulation of leukocyte differentiation GO:1902105 61 0.029
carbohydrate derivative biosynthetic process GO:1901137 207 0.029
positive regulation of exocytosis GO:0045921 35 0.029
regulation of intracellular protein transport GO:0033157 123 0.029
organic hydroxy compound transport GO:0015850 63 0.029
granzyme a production GO:0035746 1 0.029
nucleoside triphosphate metabolic process GO:0009141 422 0.028
protein maturation GO:0051604 233 0.028
regulation of cytoplasmic transport GO:1903649 149 0.028
viral life cycle GO:0019058 132 0.028
mitotic cell cycle GO:0000278 326 0.028
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 3 0.028
positive regulation of endocytosis GO:0045807 42 0.028
muscle cell proliferation GO:0033002 35 0.028
organonitrogen compound biosynthetic process GO:1901566 200 0.028
membrane organization GO:0061024 292 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
acute inflammatory response to antigenic stimulus GO:0002438 1 0.028
syncytium formation by plasma membrane fusion GO:0000768 2 0.028
positive regulation of cytoplasmic transport GO:1903651 82 0.027
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.027
eosinophil mediated immunity GO:0002447 2 0.027
positive regulation of nucleotide catabolic process GO:0030813 185 0.027
regulation of membrane potential GO:0042391 95 0.027
response to fibroblast growth factor GO:0071774 39 0.027
cellular macromolecular complex assembly GO:0034622 324 0.026
regulation of mhc class ii biosynthetic process GO:0045346 4 0.026
lymphocyte differentiation GO:0030098 35 0.026
protein secretion GO:0009306 98 0.026
Mouse
defense response to bacterium GO:0042742 63 0.026
cell cell signaling GO:0007267 155 0.026
positive regulation of secretion GO:0051047 116 0.026
hormone secretion GO:0046879 65 0.026
regulation of cytokine mediated signaling pathway GO:0001959 41 0.026
plasma membrane organization GO:0007009 115 0.026
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.026
cell projection organization GO:0030030 252 0.026
leukocyte cell cell adhesion GO:0007159 37 0.025
hormone transport GO:0009914 68 0.025
nucleoside catabolic process GO:0009164 408 0.025
actin filament organization GO:0007015 128 0.025
b cell activation GO:0042113 33 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
protein processing GO:0016485 226 0.025
regulation of cysteine type endopeptidase activity GO:2000116 127 0.025
regulation of peptide hormone secretion GO:0090276 41 0.025

PLEK disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.078
disease by infectious agent DOID:0050117 34 0.076
disease of cellular proliferation DOID:14566 174 0.039
cancer DOID:162 167 0.029