|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.969
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.959
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.925
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.802
|
|
|
|
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway
|
GO:0007196 |
4 |
0.733
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.730
|
|
|
|
dimeric g protein coupled receptor signaling pathway
|
GO:0038042 |
1 |
0.719
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.650
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.617
|
Zebrafish Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.607
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.587
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.582
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.543
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.539
|
|
|
|
system process
|
GO:0003008 |
349 |
0.518
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.512
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.512
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.505
|
Zebrafish Fly |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.490
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.484
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.483
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.483
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.479
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.471
|
|
|
|
g protein coupled glutamate receptor signaling pathway
|
GO:0007216 |
8 |
0.461
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.451
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.424
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.396
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.381
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.356
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.354
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.350
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.348
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.343
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.342
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.341
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.341
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.338
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.338
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.332
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.325
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.323
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.319
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.316
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.307
|
Fly |
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.294
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.294
|
|
|
|
regulation of atrial cardiac muscle cell membrane repolarization
|
GO:0060372 |
4 |
0.279
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.269
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.257
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.252
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.252
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.252
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.251
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.240
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.238
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.231
|
Fly |
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.227
|
|
|
|
cellular response to disaccharide stimulus
|
GO:0071324 |
1 |
0.225
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.220
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.216
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.214
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.208
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.206
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.206
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.200
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.193
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.193
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.191
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.190
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.188
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.185
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.183
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.182
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.181
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.175
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.175
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.171
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.171
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.170
|
Zebrafish Rat Fly |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.169
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.169
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.168
|
Fly |
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.167
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.167
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.167
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.165
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.160
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.160
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.159
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.157
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.157
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.155
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.151
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.151
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.147
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.145
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.139
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.138
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.138
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.136
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.136
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.131
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.130
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.129
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.129
|
Zebrafish Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.128
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.128
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.125
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.125
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.124
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.124
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.119
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.118
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.117
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.116
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.115
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.114
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.112
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.112
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.111
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.107
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.106
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.104
|
|
|
|
memory
|
GO:0007613 |
3 |
0.104
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.103
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.103
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.103
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.102
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.100
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.100
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.100
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.099
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.098
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.096
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.095
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.093
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.093
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.093
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.092
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
35 |
0.092
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.090
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.090
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.087
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.085
|
|
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.085
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.084
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.083
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.083
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.083
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.082
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.082
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.082
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.082
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.081
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.080
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.079
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.079
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.078
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.076
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.076
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.076
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.075
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.074
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.073
|
|
|
|
regulation of acrosome reaction
|
GO:0060046 |
4 |
0.073
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.072
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.072
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.072
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.072
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.071
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.070
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.069
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.069
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.069
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.068
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.068
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.068
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.067
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.066
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.066
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.066
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.065
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.065
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.065
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.065
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.064
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.062
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.062
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.062
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.062
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.061
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.061
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.061
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.061
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.061
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.061
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.060
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.060
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.059
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.059
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.059
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.058
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.058
|
|
|
|
adenylate cyclase inhibiting adrenergic receptor signaling pathway
|
GO:0071881 |
1 |
0.058
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.057
|
|
|
|
mating
|
GO:0007618 |
1 |
0.057
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.057
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.057
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.057
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.056
|
|
|
|
regulation of transmission of nerve impulse
|
GO:0051969 |
2 |
0.055
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.055
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.055
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.055
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.055
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.055
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.055
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.055
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
0.055
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.054
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.054
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.054
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.053
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.053
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.053
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.053
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.052
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.052
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.051
|
|
|
|
serotonin transport
|
GO:0006837 |
3 |
0.051
|
|
|
|
cellular response to corticotropin releasing hormone stimulus
|
GO:0071376 |
1 |
0.051
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.051
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.051
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.051
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.051
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.051
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.050
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.050
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.050
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.050
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.050
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.049
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.049
|
|
|
|
positive regulation of acrosome reaction
|
GO:2000344 |
4 |
0.049
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.049
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.049
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.049
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.049
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.048
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.048
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.048
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.047
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.047
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.046
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.046
|
|
|
|
catecholamine secretion
|
GO:0050432 |
1 |
0.045
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.045
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.045
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.045
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.044
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.044
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.044
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.044
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.044
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.044
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.044
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.044
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.043
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.043
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.043
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.043
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.043
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.043
|
|
|
|
phospholipase c activating adrenergic receptor signaling pathway
|
GO:0071882 |
1 |
0.042
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.042
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.042
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.042
|
|
|
|
cannabinoid signaling pathway
|
GO:0038171 |
2 |
0.042
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.042
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.042
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.042
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.042
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.041
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.041
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.041
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.041
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.040
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.040
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.040
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.040
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.040
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.040
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.040
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.040
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.040
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.040
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.039
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.039
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.039
|
|
|
|
positive regulation of phosphatidylinositol biosynthetic process
|
GO:0010513 |
3 |
0.039
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.039
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.039
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.038
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.038
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.038
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.038
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.038
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.037
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.037
|
|
|
|
detection of visible light
|
GO:0009584 |
11 |
0.037
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.037
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.037
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.037
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.036
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.036
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.036
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.036
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.035
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.035
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.035
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.035
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.035
|
Rat |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.035
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.035
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.035
|
|
|
|
response to sucrose
|
GO:0009744 |
1 |
0.035
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.034
|
Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.034
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.034
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.034
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.034
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.034
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.034
|
|
|
|
sensory perception of sweet taste
|
GO:0050916 |
2 |
0.034
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.033
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.033
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.033
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.033
|
|
|
|
adenylate cyclase inhibiting opioid receptor signaling pathway
|
GO:0031635 |
1 |
0.033
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.033
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.033
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.033
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.033
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.033
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.033
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.033
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.032
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.032
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.032
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.032
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.032
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.032
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.032
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.032
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.032
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.032
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
2 |
0.031
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.031
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
6 |
0.031
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.031
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.031
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.031
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.031
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.031
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.031
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.031
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.030
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.030
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.030
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.030
|
Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.030
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.030
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.030
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.029
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.029
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
1 |
0.029
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.029
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.029
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.029
|
|
|
|
negative regulation of endothelial cell development
|
GO:1901551 |
1 |
0.029
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.029
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.029
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.028
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.028
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.028
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.028
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.028
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.028
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.028
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.028
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.028
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.027
|
|
|
|
visual perception
|
GO:0007601 |
27 |
0.027
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.027
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.027
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.027
|
|
|
|
somatostatin signaling pathway
|
GO:0038170 |
1 |
0.027
|
|
|
|
head development
|
GO:0060322 |
108 |
0.027
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.027
|
|
|
|
positive regulation of heart rate
|
GO:0010460 |
4 |
0.027
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.027
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.026
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.026
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.026
|
Fly |
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.026
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.026
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.026
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.026
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.026
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.026
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.026
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.026
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.026
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.026
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.026
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.026
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.026
|
|
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
47 |
0.026
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.026
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.025
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.025
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.025
|
Zebrafish Fly |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.025
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.025
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.025
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
13 |
0.025
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.025
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.025
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.025
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.025
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.025
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.025
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.025
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.025
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.024
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.024
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.024
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.024
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.024
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.024
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.024
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.024
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.024
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.024
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.024
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.024
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.024
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.023
|
|
|
|
luteinizing hormone secretion
|
GO:0032275 |
1 |
0.023
|
|
|
|
response to glucagon
|
GO:0033762 |
1 |
0.023
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.023
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.023
|
|
|
|
negative regulation of camp metabolic process
|
GO:0030815 |
9 |
0.023
|
|
|
|
gamma aminobutyric acid signaling pathway
|
GO:0007214 |
3 |
0.023
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.023
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.023
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.023
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.023
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.023
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.023
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.023
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.023
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.022
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.022
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.022
|
|
|
|
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
|
GO:0044338 |
2 |
0.022
|
|
|
|
cellular response to sucrose stimulus
|
GO:0071329 |
1 |
0.022
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.022
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.022
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.022
|
|
|
|
growth
|
GO:0040007 |
202 |
0.022
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.022
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.021
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.021
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.021
|
|
|
|
response to corticotropin releasing hormone
|
GO:0043435 |
1 |
0.021
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.021
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.021
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.021
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.021
|
|
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.021
|
|
