Homo sapiens

43 known processes

MACF1

microtubule-actin crosslinking factor 1

(Aliases: ACF7,KIAA1251,FLJ45612,FLJ46776,ABP620,MACF,OFC4,KIAA0465)

MACF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection organization GO:0030030 252 0.376
Fly
neuron differentiation GO:0030182 138 0.349
Fly
nervous system development GO:0007399 293 0.312
Fly
regulation of cellular component biogenesis GO:0044087 281 0.261
Mouse Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.249
Mouse
cellular component morphogenesis GO:0032989 314 0.237
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.222
Fly
cell morphogenesis GO:0000902 296 0.219
Fly
neurogenesis GO:0022008 169 0.210
Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.193
Mouse
nucleoside catabolic process GO:0009164 408 0.192
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.163
Mouse
cell adhesion GO:0007155 325 0.160
Mouse
generation of neurons GO:0048699 152 0.151
Fly
taxis GO:0042330 157 0.146
Fly
purine containing compound catabolic process GO:0072523 411 0.144
Mouse
purine nucleoside catabolic process GO:0006152 398 0.143
Mouse
neuron development GO:0048666 113 0.143
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.138
Mouse
nucleotide catabolic process GO:0009166 408 0.135
Mouse
ribonucleotide catabolic process GO:0009261 405 0.134
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.130
Mouse Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.130
Mouse
actin filament based process GO:0030029 224 0.127
ribonucleoside catabolic process GO:0042454 406 0.123
Mouse
regulation of cell morphogenesis GO:0022604 153 0.122
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.115
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.113
Mouse
purine nucleotide catabolic process GO:0006195 405 0.113
Mouse
cellular macromolecular complex assembly GO:0034622 324 0.108
regulation of cytoskeleton organization GO:0051493 177 0.095
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.094
Mouse
system process GO:0003008 349 0.091
cell development GO:0048468 328 0.089
Fly
neuron projection development GO:0031175 106 0.088
Fly
actin cytoskeleton organization GO:0030036 207 0.082
regulation of cell differentiation GO:0045595 393 0.082
Fly
cation transport GO:0006812 331 0.081
organelle assembly GO:0070925 176 0.078
regulation of protein complex assembly GO:0043254 147 0.077
morphogenesis of embryonic epithelium GO:0016331 4 0.074
response to oxygen containing compound GO:1901700 369 0.073
membrane organization GO:0061024 292 0.072
glycosyl compound catabolic process GO:1901658 413 0.072
Mouse
circulatory system development GO:0072359 262 0.072
intracellular protein transport GO:0006886 270 0.071
single organism cellular localization GO:1902580 332 0.069
regulation of cell cycle GO:0051726 393 0.068
regulation of cellular amino acid metabolic process GO:0006521 6 0.067
negative regulation of multicellular organismal process GO:0051241 317 0.066
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.066
Mouse
cellular amine metabolic process GO:0044106 41 0.066
regulation of purine nucleotide metabolic process GO:1900542 264 0.063
inorganic ion transmembrane transport GO:0098660 231 0.063
tube morphogenesis GO:0035239 95 0.062
Mouse Fly
locomotory behavior GO:0007626 1 0.062
regulation of cell adhesion GO:0030155 166 0.062
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.062
Human Fly
ion transmembrane transport GO:0034220 338 0.060
regulation of wnt signaling pathway GO:0030111 123 0.060
Mouse
biological adhesion GO:0022610 331 0.059
Mouse
microtubule based process GO:0007017 210 0.058
neuromuscular junction development GO:0007528 3 0.058
negative regulation of developmental process GO:0051093 247 0.058
regulation of anatomical structure morphogenesis GO:0022603 286 0.057
Fly
regulation of locomotion GO:0040012 329 0.057
Mouse
organ morphogenesis GO:0009887 147 0.056
positive regulation of developmental process GO:0051094 314 0.056
Fly
oogenesis GO:0048477 2 0.055
cation transmembrane transport GO:0098655 238 0.054
salivary gland morphogenesis GO:0007435 4 0.054
enzyme linked receptor protein signaling pathway GO:0007167 303 0.054
secretion GO:0046903 254 0.054
purine ribonucleotide catabolic process GO:0009154 404 0.053
Mouse
positive regulation of axon extension GO:0045773 4 0.052
Fly
regulation of cell motility GO:2000145 299 0.052
Mouse
negative regulation of cellular component organization GO:0051129 235 0.051
Fly
transmembrane transport GO:0055085 399 0.051
vesicle mediated transport GO:0016192 371 0.051
ribonucleoside monophosphate catabolic process GO:0009158 158 0.050
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.050
Mouse
chemotaxis GO:0006935 157 0.049
Fly
guanosine containing compound catabolic process GO:1901069 239 0.049
mesonephric duct development GO:0072177 3 0.049
female gamete generation GO:0007292 2 0.049
cytoplasmic transport GO:0016482 379 0.048
post embryonic development GO:0009791 2 0.048
cell part morphogenesis GO:0032990 137 0.048
Fly
cellular response to dna damage stimulus GO:0006974 379 0.048
regulation of gtpase activity GO:0043087 180 0.047
cell projection morphogenesis GO:0048858 129 0.047
Fly
mating GO:0007618 1 0.046
positive regulation of transport GO:0051050 336 0.045
growth GO:0040007 202 0.045
Fly
cell cycle phase transition GO:0044770 173 0.045
cellular response to endogenous stimulus GO:0071495 336 0.045
regulation of cellular component size GO:0032535 82 0.045
Fly
cellular macromolecule catabolic process GO:0044265 380 0.044
guanosine containing compound metabolic process GO:1901068 244 0.044
regulation of microtubule based process GO:0032886 74 0.043
blood vessel morphogenesis GO:0048514 162 0.043
organophosphate catabolic process GO:0046434 430 0.043
Mouse
establishment of nucleus localization GO:0040023 1 0.042
amine metabolic process GO:0009308 44 0.042
regulation of protein localization GO:0032880 296 0.042
gtp catabolic process GO:0006184 237 0.041
dna modification GO:0006304 27 0.041
regulation of cellular amine metabolic process GO:0033238 11 0.041
glutamate metabolic process GO:0006536 10 0.041
hindbrain development GO:0030902 3 0.041
multicellular organismal aging GO:0010259 3 0.040
divalent inorganic cation transport GO:0072511 158 0.040
developmental cell growth GO:0048588 18 0.040
Fly
negative regulation of cell cycle GO:0045786 193 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.039
regulation of glutamine family amino acid metabolic process GO:0000820 2 0.039
tissue morphogenesis GO:0048729 96 0.039
Mouse Fly
immune response GO:0006955 307 0.039
mitotic cell cycle GO:0000278 326 0.039
secretion by cell GO:0032940 226 0.038
endomembrane system organization GO:0010256 196 0.038
cardiovascular system development GO:0072358 262 0.038
response to growth factor GO:0070848 205 0.037
response to axon injury GO:0048678 1 0.037
regulation of cell cycle process GO:0010564 266 0.037
protein localization to organelle GO:0033365 280 0.037
Mouse
regulation of odontogenesis GO:0042481 4 0.037
blood vessel development GO:0001568 172 0.037
nucleoside triphosphate catabolic process GO:0009143 394 0.036
Mouse
anterior posterior axis specification GO:0009948 2 0.036
cellular amino acid metabolic process GO:0006520 116 0.036
positive regulation of hydrolase activity GO:0051345 331 0.036
actin filament organization GO:0007015 128 0.036
gtp metabolic process GO:0046039 239 0.035
maintenance of location GO:0051235 112 0.035
inorganic cation transmembrane transport GO:0098662 194 0.035
mitotic cell cycle process GO:1903047 286 0.035
regulation of neurogenesis GO:0050767 82 0.035
Fly
determination of adult lifespan GO:0008340 2 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.034
regulation of cellular component movement GO:0051270 334 0.034
Mouse
negative regulation of catalytic activity GO:0043086 335 0.034
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.034
Fly
cell migration involved in gastrulation GO:0042074 1 0.034
regulation of actin cytoskeleton organization GO:0032956 116 0.033
ameboidal type cell migration GO:0001667 135 0.033
Mouse
organelle fission GO:0048285 149 0.033
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.033
cell fate determination GO:0001709 3 0.032
Fly
patterning of blood vessels GO:0001569 2 0.032
cellular response to oxygen containing compound GO:1901701 276 0.032
regulation of neuron differentiation GO:0045664 70 0.032
Fly
regulation of gtp catabolic process GO:0033124 180 0.032
motor neuron axon guidance GO:0008045 2 0.032
maintenance of cell polarity GO:0030011 2 0.032
Human
cellular homeostasis GO:0019725 196 0.032
epithelium development GO:0060429 227 0.032
Fly
embryo development GO:0009790 123 0.032
Mouse
segmentation GO:0035282 4 0.031
protein dna complex subunit organization GO:0071824 80 0.031
calcium ion transmembrane transport GO:0070588 76 0.031
negative regulation of locomotion GO:0040013 118 0.031
metal ion transport GO:0030001 272 0.031
divalent metal ion transport GO:0070838 152 0.030
oocyte differentiation GO:0009994 2 0.030
nerve development GO:0021675 4 0.030
atp catabolic process GO:0006200 157 0.030
Mouse
cytokinesis GO:0000910 96 0.030
semaphorin plexin signaling pathway GO:0071526 4 0.030
establishment of protein localization to membrane GO:0090150 121 0.030
blastoderm segmentation GO:0007350 2 0.030
mitotic cell cycle phase transition GO:0044772 162 0.030
negative regulation of organelle organization GO:0010639 126 0.030
Fly
regeneration GO:0031099 4 0.030
regulation of protein polymerization GO:0032271 63 0.030
regulation of cellular response to stress GO:0080135 244 0.030
negative regulation of intracellular signal transduction GO:1902532 183 0.029
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.029
Fly
regulation of growth GO:0040008 165 0.029
Fly
cell projection assembly GO:0030031 126 0.029
Fly
calcium ion transport GO:0006816 147 0.029
chemical homeostasis GO:0048878 306 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
negative regulation of gliogenesis GO:0014014 3 0.028
striated muscle contraction GO:0006941 52 0.028
response to abiotic stimulus GO:0009628 336 0.028
positive regulation of cellular component organization GO:0051130 376 0.027
Fly
ras protein signal transduction GO:0007265 73 0.027
branching involved in salivary gland morphogenesis GO:0060445 1 0.027
compound eye development GO:0048749 1 0.027
memory GO:0007613 3 0.027
spinal cord development GO:0021510 4 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
positive regulation of cell differentiation GO:0045597 211 0.026
Fly
spermatid differentiation GO:0048515 4 0.026
protein localization to membrane GO:0072657 160 0.026
nucleoside monophosphate catabolic process GO:0009125 159 0.026
Mouse
neurological system process GO:0050877 163 0.026
regulation of microtubule cytoskeleton organization GO:0070507 61 0.025
Fly
glial cell migration GO:0008347 4 0.025
limbic system development GO:0021761 3 0.025
pattern specification process GO:0007389 43 0.025
glutamine family amino acid metabolic process GO:0009064 17 0.025
reactive nitrogen species metabolic process GO:2001057 3 0.025
regulation of cell projection organization GO:0031344 107 0.025
Fly
reactive oxygen species biosynthetic process GO:1903409 4 0.025
neuroblast proliferation GO:0007405 4 0.024
muscle system process GO:0003012 81 0.024
protein catabolic process GO:0030163 325 0.024
cellular response to growth factor stimulus GO:0071363 197 0.024
muscle contraction GO:0006936 73 0.024
protein localization to plasma membrane GO:0072659 93 0.024
bmp signaling pathway GO:0030509 49 0.024
axon extension GO:0048675 13 0.024
Fly
maintenance of protein location GO:0045185 57 0.024
regulation of purine nucleotide catabolic process GO:0033121 205 0.024
negative regulation of cytoskeleton organization GO:0051494 45 0.024
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
cellular ketone metabolic process GO:0042180 80 0.024
engulfment of apoptotic cell GO:0043652 2 0.024
cellular protein catabolic process GO:0044257 261 0.023
atp metabolic process GO:0046034 176 0.023
Mouse
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.023
tube development GO:0035295 125 0.023
Mouse Fly
negative regulation of protein metabolic process GO:0051248 391 0.023
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.023
regulation of protein transport GO:0051223 213 0.023
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.023
endothelial cell migration GO:0043542 86 0.023
regulation of cell growth GO:0001558 135 0.023
Fly
negative regulation of cell cycle process GO:0010948 121 0.023
axon regeneration GO:0031103 1 0.023
central nervous system development GO:0007417 123 0.023
Fly
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
regulation of ion transport GO:0043269 189 0.023
cell growth GO:0016049 160 0.022
Fly
cell division GO:0051301 168 0.022
behavior GO:0007610 112 0.022
negative regulation of protein depolymerization GO:1901880 17 0.022
Fly
positive regulation of cellular component biogenesis GO:0044089 158 0.022
Fly
cellular ion homeostasis GO:0006873 168 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
establishment of protein localization to plasma membrane GO:0090002 68 0.021
wnt signaling pathway GO:0016055 156 0.021
Mouse
sensory perception GO:0007600 103 0.021
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.021
morphogenesis of an epithelium GO:0002009 60 0.021
Fly
regulation of cell development GO:0060284 161 0.021
Fly
defense response GO:0006952 315 0.021
regulation of mitotic cell cycle phase transition GO:1901990 118 0.021
cation homeostasis GO:0055080 189 0.021
positive regulation of gtpase activity GO:0043547 166 0.021
cellular protein complex assembly GO:0043623 188 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
Mouse
regulation of protein depolymerization GO:1901879 22 0.021
Fly
metencephalon development GO:0022037 2 0.021
microtubule polymerization or depolymerization GO:0031109 37 0.021
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.021
heart morphogenesis GO:0003007 48 0.021
cellular component assembly involved in morphogenesis GO:0010927 73 0.021
kidney development GO:0001822 53 0.021
cell junction assembly GO:0034329 67 0.021
Human Mouse
regulation of mitotic cell cycle GO:0007346 189 0.021
cellular chemical homeostasis GO:0055082 180 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
endocytosis GO:0006897 159 0.020
somatic stem cell maintenance GO:0035019 4 0.020
protein ubiquitination GO:0016567 314 0.020
muscle cell cellular homeostasis GO:0046716 3 0.020
neural tube closure GO:0001843 3 0.020
protein targeting GO:0006605 187 0.020
Mouse
methylation GO:0032259 106 0.020
cerebral cortex radially oriented cell migration GO:0021799 1 0.020
nuclear migration GO:0007097 1 0.020
angiogenesis GO:0001525 147 0.020
vasculature development GO:0001944 181 0.020
regulation of anatomical structure size GO:0090066 101 0.020
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
protein maturation GO:0051604 233 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
single organism membrane organization GO:0044802 268 0.020
positive regulation of cell cycle GO:0045787 140 0.020
negative regulation of cell adhesion GO:0007162 64 0.019
negative regulation of cell cycle phase transition GO:1901988 89 0.019
inner ear morphogenesis GO:0042472 4 0.019
regulation of multi organism process GO:0043900 157 0.019
sequestering of calcium ion GO:0051208 17 0.019
response to transforming growth factor beta GO:0071559 94 0.019
digestive system development GO:0055123 75 0.019
Mouse
protein modification by small protein removal GO:0070646 92 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
epidermis development GO:0008544 59 0.019
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.019
maintenance of location in cell GO:0051651 62 0.019
single organism reproductive process GO:0044702 98 0.019
regulation of cell projection assembly GO:0060491 47 0.019
Fly
digestive tract development GO:0048565 75 0.019
Mouse
associative learning GO:0008306 1 0.019
apoptotic signaling pathway GO:0097190 268 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
embryonic epithelial tube formation GO:0001838 4 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
anatomical structure homeostasis GO:0060249 100 0.018
vocalization behavior GO:0071625 11 0.018
gland development GO:0048732 48 0.018
negative regulation of cell death GO:0060548 345 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.018
protein localization to adherens junction GO:0071896 2 0.018
regulation of membrane potential GO:0042391 95 0.018
mitotic nuclear division GO:0007067 119 0.018
cellular metal ion homeostasis GO:0006875 146 0.018
regulation of proteolysis GO:0030162 293 0.018
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.018
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.018
Fly
negative regulation of phosphorylation GO:0042326 174 0.018
ion homeostasis GO:0050801 230 0.018
actin filament based movement GO:0030048 17 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.017
protein targeting to nucleus GO:0044744 104 0.017
cellular response to nitrogen compound GO:1901699 144 0.017
synaptic vesicle recycling GO:0036465 3 0.017
negative regulation of transport GO:0051051 176 0.017
regulation of kinase activity GO:0043549 314 0.017
interspecies interaction between organisms GO:0044419 156 0.017
distal tubule development GO:0072017 4 0.017
dna repair GO:0006281 198 0.017
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.017
positive regulation of cell death GO:0010942 263 0.017
regulation of innate immune response GO:0045088 97 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
adult locomotory behavior GO:0008344 1 0.017
maintenance of protein location in cell GO:0032507 56 0.017
reproductive process GO:0022414 106 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
negative regulation of mitotic cell cycle GO:0045930 102 0.017
nuclear division GO:0000280 128 0.016
regulation of protein kinase activity GO:0045859 289 0.016
response to lipid GO:0033993 206 0.016
regulation of secretion by cell GO:1903530 177 0.016
regulation of protein binding GO:0043393 66 0.016
regulation of response to dna damage stimulus GO:2001020 94 0.016
muscle structure development GO:0061061 98 0.016
protein deubiquitination GO:0016579 79 0.016
regulation of mapk cascade GO:0043408 262 0.016
cellular cation homeostasis GO:0030003 163 0.016
regulation of ras protein signal transduction GO:0046578 155 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.016
Fly
embryonic placenta development GO:0001892 1 0.016
mitotic cell cycle checkpoint GO:0007093 68 0.016
sodium ion transmembrane transport GO:0035725 59 0.016
melanin metabolic process GO:0006582 1 0.016
jak stat cascade GO:0007259 46 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
neurotransmitter secretion GO:0007269 4 0.016
oocyte development GO:0048599 1 0.016
meiosis i GO:0007127 4 0.016
positive regulation of organelle organization GO:0010638 195 0.016
neuron projection regeneration GO:0031102 1 0.016
organ formation GO:0048645 3 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
cell cycle checkpoint GO:0000075 117 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
protein dna complex assembly GO:0065004 64 0.015
nitrogen compound transport GO:0071705 191 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
dephosphorylation GO:0016311 209 0.015
thalamus development GO:0021794 2 0.015
regulation of intracellular transport GO:0032386 195 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
Mouse
regulation of transporter activity GO:0032409 82 0.015
negative regulation of protein modification process GO:0031400 200 0.015
plasma membrane organization GO:0007009 115 0.015
sequestering of metal ion GO:0051238 24 0.015
regulation of transferase activity GO:0051338 355 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
pharynx development GO:0060465 1 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
cardiac muscle contraction GO:0060048 34 0.015
intracellular mrna localization GO:0008298 1 0.015
neural tube formation GO:0001841 3 0.015
cerebellum development GO:0021549 2 0.015
negative regulation of protein complex disassembly GO:0043242 20 0.015
Fly
single organismal cell cell adhesion GO:0016337 148 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
detection of stimulus GO:0051606 85 0.014
positive regulation of catabolic process GO:0009896 310 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
regulation of protein maturation GO:1903317 150 0.014
cell substrate adhesion GO:0031589 132 0.014
Mouse
establishment of planar polarity GO:0001736 3 0.014
golgi vesicle transport GO:0048193 80 0.014
cellular calcium ion homeostasis GO:0006874 117 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
establishment of organelle localization GO:0051656 59 0.014
dna templated transcription initiation GO:0006352 35 0.014
mitotic spindle elongation GO:0000022 4 0.014
response to cytokine GO:0034097 232 0.014
regulation of jnk cascade GO:0046328 73 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.014
calcium ion homeostasis GO:0055074 122 0.014
regulation of protein processing GO:0070613 150 0.014
protein processing GO:0016485 226 0.014
somitogenesis GO:0001756 2 0.014
presynaptic membrane assembly GO:0097105 1 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
cellular component disassembly GO:0022411 92 0.014
Fly
cerebral cortex cell migration GO:0021795 3 0.014
positive regulation of cell projection organization GO:0031346 64 0.014
Fly
regulation of cell shape GO:0008360 48 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
cell cell signaling GO:0007267 155 0.013
positive regulation of wnt signaling pathway GO:0030177 54 0.013
Mouse
response to nitrogen compound GO:1901698 184 0.013
regulation of cytokine production GO:0001817 232 0.013
morphogenesis of a polarized epithelium GO:0001738 3 0.013
long term memory GO:0007616 2 0.013
regulation of homeostatic process GO:0032844 121 0.013
regulation of dna metabolic process GO:0051052 153 0.013
humoral immune response GO:0006959 49 0.013
regulation of nervous system development GO:0051960 88 0.013
Fly
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
Mouse
negative regulation of catabolic process GO:0009895 104 0.013
regulation of chromosome organization GO:0033044 103 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.013
regulation of protein catabolic process GO:0042176 155 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
convergent extension involved in gastrulation GO:0060027 1 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
protein oligomerization GO:0051259 173 0.013
head development GO:0060322 108 0.013
Fly
organelle localization GO:0051640 84 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
receptor metabolic process GO:0043112 81 0.013
epidermis morphogenesis GO:0048730 3 0.013
regulation of metal ion transport GO:0010959 120 0.013
immune effector process GO:0002252 159 0.013
positive regulation of cell development GO:0010720 92 0.013
Fly
rho protein signal transduction GO:0007266 26 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
regulation of ion transmembrane transport GO:0034765 132 0.013
primary neural tube formation GO:0014020 3 0.013
synaptic vesicle exocytosis GO:0016079 3 0.013
synaptic vesicle endocytosis GO:0048488 2 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
tripartite regional subdivision GO:0007351 2 0.013
dna methylation or demethylation GO:0044728 19 0.013
dendrite development GO:0016358 24 0.013
Fly
regulation of stress activated mapk cascade GO:0032872 84 0.013
synaptic transmission cholinergic GO:0007271 2 0.013
convergent extension GO:0060026 1 0.013
negative regulation of cell migration GO:0030336 102 0.013
response to other organism GO:0051707 261 0.013
stress activated protein kinase signaling cascade GO:0031098 94 0.012
regulation of transmembrane transport GO:0034762 139 0.012
developmental programmed cell death GO:0010623 3 0.012
regulation of dephosphorylation GO:0035303 96 0.012
cell junction organization GO:0034330 79 0.012
Human Mouse
protein polymerization GO:0051258 71 0.012
synaptic transmission GO:0007268 61 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
positive regulation of cell migration GO:0030335 172 0.012
embryonic morphogenesis GO:0048598 85 0.012
Mouse
positive regulation of nervous system development GO:0051962 54 0.012
Fly
negative regulation of programmed cell death GO:0043069 321 0.012
developmental growth involved in morphogenesis GO:0060560 23 0.012
Fly
chromatin modification GO:0016568 298 0.012
single organism nuclear import GO:1902593 104 0.012
protein localization to nucleus GO:0034504 136 0.012
metal ion homeostasis GO:0055065 169 0.012
nuclear import GO:0051170 106 0.012
sensory perception of smell GO:0007608 2 0.012
reproduction GO:0000003 63 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
circulatory system process GO:0003013 113 0.012
regulation of peptidase activity GO:0052547 180 0.012

MACF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.033
central nervous system disease DOID:331 186 0.033
neurodegenerative disease DOID:1289 102 0.033
nervous system disease DOID:863 431 0.033
cancer DOID:162 167 0.028
organ system cancer DOID:0050686 164 0.025
sensory system disease DOID:0050155 203 0.017
disease of mental health DOID:150 70 0.017
muscular disease DOID:0080000 114 0.015
Human
musculoskeletal system disease DOID:17 223 0.015
Human