|
|
glutathione metabolic process
|
GO:0006749 |
20 |
0.992
|
|
|
|
glutathione biosynthetic process
|
GO:0006750 |
4 |
0.944
|
|
|
|
nonribosomal peptide biosynthetic process
|
GO:0019184 |
4 |
0.928
|
|
|
|
dicarboxylic acid metabolic process
|
GO:0043648 |
29 |
0.757
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.738
|
|
|
|
glutamate metabolic process
|
GO:0006536 |
10 |
0.718
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.683
|
|
|
|
cellular modified amino acid biosynthetic process
|
GO:0042398 |
15 |
0.589
|
|
|
|
cellular amino acid biosynthetic process
|
GO:0008652 |
30 |
0.577
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.523
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.508
|
|
|
|
cysteine metabolic process
|
GO:0006534 |
4 |
0.462
|
Mouse |
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.460
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.454
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.370
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.359
|
|
|
|
glutamine family amino acid metabolic process
|
GO:0009064 |
17 |
0.327
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.325
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.307
|
|
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.304
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.297
|
|
|
|
sulfur amino acid metabolic process
|
GO:0000096 |
14 |
0.276
|
Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.275
|
Mouse |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.272
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.252
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.247
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.246
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.241
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.241
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.232
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.229
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.228
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.213
|
Mouse |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.210
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.197
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.188
|
Mouse |
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.185
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.182
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.181
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.178
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.177
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.176
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.173
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.170
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.165
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.161
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.161
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.157
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.153
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.151
|
|
|
|
water soluble vitamin metabolic process
|
GO:0006767 |
6 |
0.150
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.138
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.136
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.133
|
Mouse |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.130
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.127
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.123
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.119
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.115
|
Mouse |
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.114
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.114
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.111
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.106
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.105
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.099
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.097
|
|
|
|
system process
|
GO:0003008 |
349 |
0.094
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.094
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.093
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.092
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.091
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.090
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.087
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.085
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.081
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.080
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.080
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.078
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.077
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.076
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.075
|
Mouse |
|
|
response to superoxide
|
GO:0000303 |
6 |
0.074
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.073
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.072
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.071
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.070
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.069
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.069
|
|
|
|
response to oxygen radical
|
GO:0000305 |
6 |
0.069
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.068
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.065
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.065
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.063
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.062
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.062
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.058
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.056
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.055
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.054
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.053
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.047
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.047
|
|
|
|
regulation of mitochondrial depolarization
|
GO:0051900 |
6 |
0.047
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.046
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.045
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.044
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.044
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.044
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.043
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.043
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.043
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.043
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.043
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.043
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.041
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.041
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.041
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.041
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.041
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.040
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.040
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.040
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.040
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.039
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.039
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.038
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.038
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.038
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.038
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.038
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.038
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.038
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.038
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.037
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.037
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.037
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.037
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.036
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.036
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.035
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.034
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.034
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.034
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.034
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.033
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.033
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.033
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.033
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.032
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.032
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.032
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.031
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.031
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.031
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.031
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.030
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.030
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.030
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.030
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.029
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.029
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.029
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.029
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.029
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.028
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.028
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.028
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.028
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.027
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.027
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.027
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.027
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.027
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.027
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.026
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.026
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.026
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.025
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.025
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.025
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.025
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.025
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.025
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.024
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.024
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.024
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.024
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.024
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.024
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.024
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.024
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.024
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.023
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.023
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.023
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.023
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.023
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.023
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.023
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.023
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.022
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.022
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.022
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.022
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.022
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.022
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.022
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.022
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.022
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.022
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.022
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.022
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.021
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.021
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.021
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.021
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.021
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.021
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.021
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.021
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.021
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.021
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.021
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.021
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.021
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.021
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.021
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.021
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.021
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.020
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.020
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.020
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.020
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.020
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.020
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.020
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.020
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.020
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.020
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.019
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.019
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.019
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.019
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.019
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.019
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.019
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.019
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.019
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.019
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.019
|
|
|
|
growth
|
GO:0040007 |
202 |
0.019
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.019
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.019
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.019
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.019
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.019
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.019
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.019
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.019
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.019
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.018
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.018
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.018
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.018
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.018
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.018
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.018
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.018
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.018
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.018
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.018
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.017
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.017
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.017
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.017
|
|
|
|
mitochondrial depolarization
|
GO:0051882 |
6 |
0.017
|
Mouse |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.017
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.017
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.017
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.017
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.017
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.017
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.017
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.017
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.017
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.017
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.017
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.017
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.017
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.017
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.017
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.017
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.016
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.016
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.016
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.016
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.016
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.016
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.016
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.016
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.016
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.016
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.016
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.016
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.016
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.016
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.016
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.016
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.016
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.016
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.016
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.016
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.016
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.016
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.015
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.015
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.015
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.015
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.015
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.015
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.015
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.015
|
|
|
|
response to heat
|
GO:0009408 |
21 |
0.015
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.015
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.015
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.015
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.015
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.015
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.015
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.015
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.015
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.015
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.015
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.015
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.015
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.015
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.015
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.015
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.015
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.015
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.015
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.014
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.014
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.014
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.014
|
|
|
|
phospholipid biosynthetic process
|
GO:0008654 |
44 |
0.014
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.014
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.014
|
|
|
|
testosterone biosynthetic process
|
GO:0061370 |
2 |
0.014
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.014
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.014
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.014
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.014
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.014
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.014
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.014
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.014
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.014
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.014
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.014
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.014
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.014
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.014
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.014
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.014
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.014
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.014
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.014
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.014
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.014
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.014
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.014
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.014
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.014
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.014
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.014
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.014
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.014
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.013
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.013
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.013
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.013
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.013
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.013
|
|
|
|
protein folding
|
GO:0006457 |
38 |
0.013
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.013
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.013
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.013
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.013
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.013
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.013
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.013
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.013
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.013
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.013
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.013
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.013
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.013
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.013
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.013
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.012
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.012
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.012
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.012
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.012
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.012
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.012
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.012
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.012
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.012
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.012
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.012
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.012
|
|
|
|
head development
|
GO:0060322 |
108 |
0.012
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.012
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.012
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.012
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.012
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.012
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.012
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.012
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.012
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.012
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.012
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.012
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.012
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.012
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.012
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.012
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.012
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.012
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.012
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
20 |
0.012
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.012
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.012
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.012
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.012
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.012
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.012
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.012
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.012
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.012
|
|
|
|
regulation of testosterone biosynthetic process
|
GO:2000224 |
2 |
0.012
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.012
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.012
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.012
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.012
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.012
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.012
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.012
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.012
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.012
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.012
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.012
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.012
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.012
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.011
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.011
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.011
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.011
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.011
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.011
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.011
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.011
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.011
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.011
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.011
|
|
|
|
nucleosome organization
|
GO:0034728 |
66 |
0.011
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.011
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.011
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.011
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.011
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.011
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.011
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.011
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.011
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.011
|
|