Homo sapiens

41 known processes

UBQLN4

ubiquilin 4

(Aliases: A1U,C1orf6,UBIN,CIP75)

UBQLN4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tonic smooth muscle contraction GO:0014820 3 0.920
positive regulation of developmental process GO:0051094 314 0.670
rna interference GO:0016246 4 0.596
artery smooth muscle contraction GO:0014824 3 0.478
biological adhesion GO:0022610 331 0.465
defense response GO:0006952 315 0.320
nucleoside phosphate catabolic process GO:1901292 412 0.315
positive regulation of catabolic process GO:0009896 310 0.314
purine nucleoside catabolic process GO:0006152 398 0.310
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.298
response to oxidative stress GO:0006979 121 0.285
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.276
Human
protein ubiquitination GO:0016567 314 0.272
Human
regulation of cytoskeleton organization GO:0051493 177 0.233
cell adhesion GO:0007155 325 0.232
regulation of cell growth GO:0001558 135 0.221
multicellular organismal aging GO:0010259 3 0.195
Worm
positive regulation of mapk cascade GO:0043410 190 0.194
modification dependent protein catabolic process GO:0019941 209 0.185
regulation of multi organism process GO:0043900 157 0.181
nucleoside triphosphate metabolic process GO:0009141 422 0.174
ribonucleoside catabolic process GO:0042454 406 0.172
positive regulation of cell differentiation GO:0045597 211 0.170
regulation of proteolysis GO:0030162 293 0.164
intrinsic apoptotic signaling pathway GO:0097193 127 0.162
Human
regulation of cell cycle GO:0051726 393 0.153
cell growth GO:0016049 160 0.153
apoptotic signaling pathway GO:0097190 268 0.153
Human
growth GO:0040007 202 0.151
response to organic cyclic compound GO:0014070 204 0.147
purine nucleotide catabolic process GO:0006195 405 0.145
posttranscriptional gene silencing by rna GO:0035194 25 0.144
regulation of sodium dependent phosphate transport GO:2000118 2 0.144
posttranscriptional gene silencing GO:0016441 25 0.137
response to oxygen containing compound GO:1901700 369 0.134
ribonucleoside triphosphate metabolic process GO:0009199 412 0.125
mitochondrion organization GO:0007005 156 0.124
organophosphate catabolic process GO:0046434 430 0.123
positive regulation of programmed cell death GO:0043068 249 0.123
positive regulation of nucleoside metabolic process GO:0045979 186 0.120
positive regulation of secretion by cell GO:1903532 108 0.116
anion transport GO:0006820 161 0.114
cellular homeostasis GO:0019725 196 0.113
endosomal transport GO:0016197 129 0.110
negative regulation of protein phosphorylation GO:0001933 140 0.107
regulation of nucleoside metabolic process GO:0009118 209 0.106
vesicle mediated transport GO:0016192 371 0.105
establishment of protein localization to membrane GO:0090150 121 0.104
cellular macromolecule catabolic process GO:0044265 380 0.102
cellular response to nitrogen compound GO:1901699 144 0.101
modification dependent macromolecule catabolic process GO:0043632 212 0.100
single organism membrane organization GO:0044802 268 0.098
response to nitrogen compound GO:1901698 184 0.096
protein localization to membrane GO:0072657 160 0.094
purine nucleoside triphosphate catabolic process GO:0009146 392 0.094
regulation of protein catabolic process GO:0042176 155 0.093
positive regulation of acrosome reaction GO:2000344 4 0.093
proteasomal protein catabolic process GO:0010498 176 0.092
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.091
cellular response to histamine GO:0071420 3 0.091
regulation of growth GO:0040008 165 0.090
actin cytoskeleton organization GO:0030036 207 0.089
cellular chemical homeostasis GO:0055082 180 0.088
response to purine containing compound GO:0014074 40 0.085
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.082
cellular metal ion homeostasis GO:0006875 146 0.081
cellular ketone metabolic process GO:0042180 80 0.076
jak stat cascade GO:0007259 46 0.076
regulation of acrosome reaction GO:0060046 4 0.075
nucleoside triphosphate catabolic process GO:0009143 394 0.072
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.072
startle response GO:0001964 3 0.071
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.069
guanosine containing compound catabolic process GO:1901069 239 0.069
regulation of map kinase activity GO:0043405 108 0.067
response to extracellular stimulus GO:0009991 85 0.066
response to inorganic substance GO:0010035 127 0.064
gene silencing GO:0016458 49 0.063
skin development GO:0043588 76 0.063
regulation of cell migration GO:0030334 289 0.062
purine containing compound catabolic process GO:0072523 411 0.062
ribonucleoside triphosphate catabolic process GO:0009203 391 0.060
cytokinesis GO:0000910 96 0.059
positive regulation of proteolysis GO:0045862 142 0.058
protein localization to endoplasmic reticulum GO:0070972 19 0.057
metal ion transport GO:0030001 272 0.056
female gamete generation GO:0007292 2 0.055
regulation of mapk cascade GO:0043408 262 0.055
intracellular protein transport GO:0006886 270 0.054
regulation of canonical wnt signaling pathway GO:0060828 88 0.054
brain morphogenesis GO:0048854 1 0.053
response to tumor necrosis factor GO:0034612 76 0.053
chemical homeostasis GO:0048878 306 0.053
gtp metabolic process GO:0046039 239 0.050
membrane organization GO:0061024 292 0.050
antigen receptor mediated signaling pathway GO:0050851 38 0.049
segmentation GO:0035282 4 0.049
regulation of anatomical structure morphogenesis GO:0022603 286 0.049
tissue morphogenesis GO:0048729 96 0.049
innate immune response GO:0045087 178 0.048
negative regulation of catalytic activity GO:0043086 335 0.046
hematopoietic or lymphoid organ development GO:0048534 186 0.046
positive regulation of cell development GO:0010720 92 0.045
protein polyubiquitination GO:0000209 110 0.045
mrna metabolic process GO:0016071 175 0.045
immune response GO:0006955 307 0.044
inorganic cation transmembrane transport GO:0098662 194 0.044
positive regulation of epithelial cell proliferation GO:0050679 65 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
regulation of gene expression epigenetic GO:0040029 73 0.043
positive regulation of secretion GO:0051047 116 0.043
apoptotic mitochondrial changes GO:0008637 57 0.043
cellular response to oxygen containing compound GO:1901701 276 0.042
cellular response to biotic stimulus GO:0071216 71 0.042
response to metal ion GO:0010038 84 0.042
metal ion homeostasis GO:0055065 169 0.042
positive regulation of cell proliferation GO:0008284 301 0.042
positive regulation of protein phosphorylation GO:0001934 313 0.042
purine ribonucleoside metabolic process GO:0046128 437 0.041
guanosine containing compound metabolic process GO:1901068 244 0.040
inorganic ion transmembrane transport GO:0098660 231 0.040
cellular response to nutrient levels GO:0031669 69 0.039
cellular divalent inorganic cation homeostasis GO:0072503 128 0.038
regulation of cellular component movement GO:0051270 334 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.037
calcium ion transmembrane transport GO:0070588 76 0.037
regulation of proteasomal protein catabolic process GO:0061136 87 0.037
regulation of cellular protein catabolic process GO:1903362 96 0.037
chromatin modification GO:0016568 298 0.037
negative regulation of cell growth GO:0030308 83 0.037
positive regulation of immune system process GO:0002684 283 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.035
organic hydroxy compound metabolic process GO:1901615 147 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.034
regulation of secretion GO:0051046 194 0.034
response to peptide hormone GO:0043434 61 0.033
regulation of purine nucleotide metabolic process GO:1900542 264 0.033
positive regulation of cell growth GO:0030307 48 0.033
response to organonitrogen compound GO:0010243 156 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.032
transmembrane transport GO:0055085 399 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.032
protein catabolic process GO:0030163 325 0.032
regulation of cellular component biogenesis GO:0044087 281 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.032
regulation of cellular component size GO:0032535 82 0.032
autophagy GO:0006914 88 0.032
purine nucleotide biosynthetic process GO:0006164 84 0.032
positive regulation of nucleotide catabolic process GO:0030813 185 0.031
response to organophosphorus GO:0046683 41 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.030
response to external biotic stimulus GO:0043207 261 0.030
methylation GO:0032259 106 0.030
ribonucleoside monophosphate metabolic process GO:0009161 187 0.030
synaptic transmission GO:0007268 61 0.030
developmental growth GO:0048589 48 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.029
regulation of cell adhesion GO:0030155 166 0.029
regulation of transferase activity GO:0051338 355 0.029
positive regulation of cell death GO:0010942 263 0.029
blastocyst development GO:0001824 3 0.029
response to uv GO:0009411 73 0.029
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.029
purine containing compound biosynthetic process GO:0072522 88 0.029
covalent chromatin modification GO:0016569 254 0.029
negative regulation of locomotion GO:0040013 118 0.029
positive regulation of phosphorylation GO:0042327 394 0.029
negative regulation of sodium dependent phosphate transport GO:2000119 1 0.028
protein localization to organelle GO:0033365 280 0.028
regulation of viral process GO:0050792 103 0.028
regulation of receptor mediated endocytosis GO:0048259 32 0.028
regulation of cellular response to growth factor stimulus GO:0090287 76 0.028
cellular response to external stimulus GO:0071496 111 0.028
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.028
cellular response to glucocorticoid stimulus GO:0071385 4 0.028
generation of precursor metabolites and energy GO:0006091 68 0.028
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.028
signal transduction by phosphorylation GO:0023014 297 0.027
i kappab kinase nf kappab signaling GO:0007249 166 0.027
negative regulation of hydrolase activity GO:0051346 182 0.027
regulation of binding GO:0051098 111 0.027
exocytosis GO:0006887 71 0.027
cyclic nucleotide metabolic process GO:0009187 82 0.027
response to hormone GO:0009725 175 0.026
histone modification GO:0016570 251 0.026
negative regulation of ectodermal cell fate specification GO:0042666 1 0.026
cellular response to molecule of bacterial origin GO:0071219 62 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
posttranscriptional regulation of gene expression GO:0010608 213 0.026
regulation of vesicle mediated transport GO:0060627 130 0.026
behavior GO:0007610 112 0.026
positive regulation of transport GO:0051050 336 0.026
regulation of ion transport GO:0043269 189 0.026
positive regulation of cellular component organization GO:0051130 376 0.026
negative regulation of growth GO:0045926 97 0.025
syncytium formation by plasma membrane fusion GO:0000768 2 0.025
multicellular organismal response to stress GO:0033555 1 0.025
response to camp GO:0051591 25 0.025
regulation of cell motility GO:2000145 299 0.024
response to biotic stimulus GO:0009607 276 0.024
nucleotide catabolic process GO:0009166 408 0.024
single organism cellular localization GO:1902580 332 0.024
regulation of protein kinase activity GO:0045859 289 0.024
single organism reproductive process GO:0044702 98 0.024
cellular polysaccharide biosynthetic process GO:0033692 21 0.024
ribonucleotide catabolic process GO:0009261 405 0.023
secretion by cell GO:0032940 226 0.023
myeloid leukocyte differentiation GO:0002573 60 0.023
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.023
regulation of ectoderm development GO:2000383 1 0.023
determination of adult lifespan GO:0008340 2 0.022
Worm
cation homeostasis GO:0055080 189 0.022
regulation of carbohydrate metabolic process GO:0006109 54 0.022
enzyme linked receptor protein signaling pathway GO:0007167 303 0.022
reproduction GO:0000003 63 0.022
regulation of epidermis development GO:0045682 19 0.022
nucleoside monophosphate metabolic process GO:0009123 191 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
receptor metabolic process GO:0043112 81 0.021
response to hydrogen peroxide GO:0042542 40 0.021
cellular response to organic cyclic compound GO:0071407 127 0.021
protein deubiquitination GO:0016579 79 0.021
positive regulation of cellular component movement GO:0051272 181 0.021
regeneration GO:0031099 4 0.021
regulation of nucleotide catabolic process GO:0030811 205 0.021
epidermis development GO:0008544 59 0.021
regulation of protein processing GO:0070613 150 0.021
negative regulation of cellular component organization GO:0051129 235 0.020
regulation of gtp catabolic process GO:0033124 180 0.020
keratinocyte apoptotic process GO:0097283 1 0.020
positive regulation of neurogenesis GO:0050769 49 0.020
fat cell differentiation GO:0045444 32 0.020
positive regulation of jnk cascade GO:0046330 52 0.020
cellular calcium ion homeostasis GO:0006874 117 0.020
vasculature development GO:0001944 181 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
reproductive process GO:0022414 106 0.019
cell substrate adhesion GO:0031589 132 0.019
phospholipid metabolic process GO:0006644 99 0.019
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.019
cellular response to oxygen levels GO:0071453 55 0.019
Human
locomotory behavior GO:0007626 1 0.019
positive regulation of growth GO:0045927 58 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
response to alcohol GO:0097305 64 0.019
regulation of synaptic plasticity GO:0048167 3 0.019
cytoplasmic transport GO:0016482 379 0.019
regulation of cellular response to stress GO:0080135 244 0.019
Human
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.019
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.019
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.019
regulation of actin filament based process GO:0032970 141 0.019
regulation of dna binding GO:0051101 37 0.018
negative regulation of viral process GO:0048525 66 0.018
negative regulation of immune system process GO:0002683 136 0.018
spermatid differentiation GO:0048515 4 0.018
regulation of muscle cell differentiation GO:0051147 31 0.018
regulation of anatomical structure size GO:0090066 101 0.018
regulation of cell differentiation GO:0045595 393 0.018
leukocyte activation GO:0045321 164 0.018
negative regulation of ectoderm development GO:2000384 1 0.018
positive regulation of exocytosis GO:0045921 35 0.018
positive regulation of cell migration GO:0030335 172 0.018
oxidation reduction process GO:0055114 396 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
response to abiotic stimulus GO:0009628 336 0.017
Human
regulation of autophagy GO:0010506 52 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
regulation of fibroblast proliferation GO:0048145 32 0.017
regulation of protein maturation GO:1903317 150 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.017
macromolecule methylation GO:0043414 97 0.017
ossification GO:0001503 121 0.017
cellular protein catabolic process GO:0044257 261 0.016
receptor mediated endocytosis GO:0006898 84 0.016
fructose metabolic process GO:0006000 3 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.016
Human
positive regulation of protein kinase activity GO:0045860 190 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.016
histone h3 acetylation GO:0043966 45 0.016
glycerolipid metabolic process GO:0046486 107 0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.016
chromatin organization GO:0006325 351 0.015
mammary gland development GO:0030879 17 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
multi organism reproductive process GO:0044703 54 0.015
organelle fission GO:0048285 149 0.015
response to nutrient levels GO:0031667 81 0.015
protein targeting GO:0006605 187 0.015
membrane protein ectodomain proteolysis GO:0006509 33 0.015
negative regulation of axonogenesis GO:0050771 4 0.015
regulation of peptidase activity GO:0052547 180 0.015
blood vessel morphogenesis GO:0048514 162 0.015
cellular response to ammonium ion GO:0071242 4 0.015
regulation of cell substrate adhesion GO:0010810 68 0.015
positive regulation of cell projection organization GO:0031346 64 0.015
cellular response to endogenous stimulus GO:0071495 336 0.014
ion homeostasis GO:0050801 230 0.014
response to peptide GO:1901652 65 0.014
visual learning GO:0008542 1 0.014
cellular cation homeostasis GO:0030003 163 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
regulation of generation of precursor metabolites and energy GO:0043467 27 0.014
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 2 0.014
convergent extension GO:0060026 1 0.014
protein targeting to membrane GO:0006612 42 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
cell cycle g1 s phase transition GO:0044843 80 0.014
gene silencing by rna GO:0031047 26 0.014
regulation of cellular response to oxidative stress GO:1900407 26 0.014
Human
actin modification GO:0030047 1 0.014
cerebellum development GO:0021549 2 0.014
cation transport GO:0006812 331 0.014
negative regulation of transferase activity GO:0051348 124 0.014
negative regulation of protein maturation GO:1903318 142 0.013
nucleoside catabolic process GO:0009164 408 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
cellular response to camp GO:0071320 21 0.013
response to other organism GO:0051707 261 0.013
maintenance of protein location GO:0045185 57 0.013
epithelium migration GO:0090132 119 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.013
negative regulation of developmental process GO:0051093 247 0.013
detection of chemical stimulus GO:0009593 55 0.013
ectodermal cell fate commitment GO:0001712 1 0.013
ectoderm formation GO:0001705 1 0.013
autocrine signaling GO:0035425 2 0.013
cellular response to hypoxia GO:0071456 51 0.013
Human
regulation of kinase activity GO:0043549 314 0.013
retina homeostasis GO:0001895 42 0.013
gland development GO:0048732 48 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.012
defense response to gram negative bacterium GO:0050829 14 0.012
memory GO:0007613 3 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
negative regulation of proteolysis GO:0045861 132 0.012
morphogenesis of an epithelium GO:0002009 60 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
regulation of locomotion GO:0040012 329 0.011
hormone metabolic process GO:0042445 61 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
response to lipid GO:0033993 206 0.011
response to fungus GO:0009620 4 0.011
stress activated mapk cascade GO:0051403 93 0.011
response to cytokine GO:0034097 232 0.011
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.011
mitotic cell cycle GO:0000278 326 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
embryo development GO:0009790 123 0.011
actin filament based process GO:0030029 224 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
regulation of ectodermal cell fate specification GO:0042665 1 0.011
cyclic nucleotide biosynthetic process GO:0009190 61 0.011
cell division GO:0051301 168 0.011
positive regulation of organelle organization GO:0010638 195 0.011
protein acetylation GO:0006473 116 0.011
negative regulation of multi organism process GO:0043901 92 0.011
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 2 0.011
viral process GO:0016032 146 0.011
ectodermal cell fate specification GO:0001715 1 0.011
motor neuron axon guidance GO:0008045 2 0.011
defense response to other organism GO:0098542 129 0.011
response to dexamethasone GO:0071548 1 0.010
epithelial cell proliferation GO:0050673 128 0.010
nervous system development GO:0007399 293 0.010
cellular response to potassium ion GO:0035865 5 0.010
positive regulation of ras gtpase activity GO:0032320 117 0.010
lipid biosynthetic process GO:0008610 177 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
mapk cascade GO:0000165 288 0.010
meiosis i GO:0007127 4 0.010
regulation of transcription regulatory region dna binding GO:2000677 15 0.010
amyloid precursor protein metabolic process GO:0042982 17 0.010
short term memory GO:0007614 1 0.010
regulation of chemotaxis GO:0050920 74 0.010

UBQLN4 disease predictions

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 114 0.878
musculoskeletal system disease DOID:17 223 0.878
myopathy DOID:423 104 0.154
muscle tissue disease DOID:66 113 0.154
central nervous system disease DOID:331 186 0.140
Human
neurodegenerative disease DOID:1289 102 0.140
Human
nervous system disease DOID:863 431 0.140
Human
muscular dystrophy DOID:9884 51 0.067
limb girdle muscular dystrophy DOID:11724 25 0.014
brain disease DOID:936 73 0.013