Homo sapiens

0 known processes

PREX1

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

(Aliases: KIAA1415,P-REX1)

PREX1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of tor signaling GO:0032006 30 0.856
tor signaling GO:0031929 39 0.547
rho protein signal transduction GO:0007266 26 0.494
positive regulation of rho guanyl nucleotide exchange factor activity GO:2001108 1 0.493
positive regulation of tor signaling GO:0032008 11 0.471
nucleotide catabolic process GO:0009166 408 0.407
Human Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.386
cellular amine metabolic process GO:0044106 41 0.347
regulation of cellular amino acid metabolic process GO:0006521 6 0.333
nucleoside triphosphate catabolic process GO:0009143 394 0.327
Human Mouse
cellular amino acid metabolic process GO:0006520 116 0.324
purine nucleotide catabolic process GO:0006195 405 0.321
Human Mouse
amine metabolic process GO:0009308 44 0.320
ras protein signal transduction GO:0007265 73 0.284
guanosine containing compound catabolic process GO:1901069 239 0.261
Human Mouse
positive regulation of cellular amine metabolic process GO:0033240 7 0.261
ribonucleotide catabolic process GO:0009261 405 0.239
Human Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.237
small gtpase mediated signal transduction GO:0007264 78 0.236
positive regulation of phosphorylation GO:0042327 394 0.236
organophosphate catabolic process GO:0046434 430 0.231
Human Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.224
Human Mouse
cellular ketone metabolic process GO:0042180 80 0.222
glycosyl compound catabolic process GO:1901658 413 0.221
Human Mouse
gtp catabolic process GO:0006184 237 0.217
Human Mouse
positive regulation of cell size GO:0045793 3 0.211
guanosine containing compound metabolic process GO:1901068 244 0.210
Human Mouse
purine ribonucleoside catabolic process GO:0046130 398 0.203
Human Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.193
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.188
Human Mouse
neuromuscular junction development GO:0007528 3 0.188
purine containing compound catabolic process GO:0072523 411 0.180
Human Mouse
positive regulation of rho protein signal transduction GO:0035025 4 0.177
purine nucleoside triphosphate metabolic process GO:0009144 412 0.176
Human Mouse
regulation of small gtpase mediated signal transduction GO:0051056 156 0.175
Human Mouse
actin filament based process GO:0030029 224 0.175
purine ribonucleoside metabolic process GO:0046128 437 0.172
Human Mouse
regulation of nucleotide catabolic process GO:0030811 205 0.169
Human Mouse
membrane lipid metabolic process GO:0006643 53 0.168
negative regulation of phosphorylation GO:0042326 174 0.164
nucleoside catabolic process GO:0009164 408 0.164
Human Mouse
purine nucleoside catabolic process GO:0006152 398 0.160
Human Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.154
Human Mouse
multicellular organismal aging GO:0010259 3 0.152
ribonucleoside triphosphate catabolic process GO:0009203 391 0.151
Human Mouse
cellular macromolecular complex assembly GO:0034622 324 0.150
cell projection organization GO:0030030 252 0.148
regulation of anatomical structure size GO:0090066 101 0.146
ribonucleoside catabolic process GO:0042454 406 0.144
Human Mouse
regulation of nucleotide metabolic process GO:0006140 269 0.137
Human Mouse
regulation of cell differentiation GO:0045595 393 0.133
Mouse
positive regulation of cellular component organization GO:0051130 376 0.132
Mouse
regulation of gtpase activity GO:0043087 180 0.129
Human Mouse
regulation of purine nucleotide catabolic process GO:0033121 205 0.127
Human Mouse
chemotaxis GO:0006935 157 0.126
Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.124
Human Mouse
regulation of cellular component size GO:0032535 82 0.119
purine ribonucleotide catabolic process GO:0009154 404 0.119
Human Mouse
cell development GO:0048468 328 0.119
Mouse
regulation of ras gtpase activity GO:0032318 128 0.118
Human Mouse
cellular response to dna damage stimulus GO:0006974 379 0.116
regulation of rho gtpase activity GO:0032319 66 0.115
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.114
negative regulation of cell size GO:0045792 3 0.114
nucleoside triphosphate metabolic process GO:0009141 422 0.112
Human Mouse
regulation of locomotion GO:0040012 329 0.110
regulation of ras protein signal transduction GO:0046578 155 0.107
Human Mouse
nervous system development GO:0007399 293 0.103
regulation of rho protein signal transduction GO:0035023 79 0.103
Human Mouse
regulation of cellular component movement GO:0051270 334 0.092
cellular protein complex assembly GO:0043623 188 0.092
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.091
Human Mouse
actin cytoskeleton organization GO:0030036 207 0.091
positive regulation of cellular catabolic process GO:0031331 284 0.091
Human Mouse
taxis GO:0042330 157 0.088
Mouse
regulation of gtp catabolic process GO:0033124 180 0.087
Human Mouse
cellular component morphogenesis GO:0032989 314 0.081
Mouse
peptidyl tyrosine phosphorylation GO:0018108 170 0.080
post embryonic development GO:0009791 2 0.080
lipid biosynthetic process GO:0008610 177 0.079
anatomical structure formation involved in morphogenesis GO:0048646 284 0.078
regulation of rho guanyl nucleotide exchange factor activity GO:2001106 1 0.078
regulation of actin filament polymerization GO:0030833 50 0.077
cellular response to cytokine stimulus GO:0071345 181 0.075
regulation of kinase activity GO:0043549 314 0.075
gtp metabolic process GO:0046039 239 0.075
Human Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.074
cellular lipid catabolic process GO:0044242 65 0.073
regulation of cellular component biogenesis GO:0044087 281 0.073
generation of neurons GO:0048699 152 0.072
negative regulation of phosphorus metabolic process GO:0010563 267 0.072
cellular response to oxygen containing compound GO:1901701 276 0.070
cell morphogenesis GO:0000902 296 0.070
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.069
rac protein signal transduction GO:0016601 12 0.069
peptidyl tyrosine modification GO:0018212 170 0.068
neuron projection development GO:0031175 106 0.068
vesicle mediated transport GO:0016192 371 0.066
syncytium formation by plasma membrane fusion GO:0000768 2 0.066
positive regulation of catabolic process GO:0009896 310 0.065
Human Mouse
negative regulation of transport GO:0051051 176 0.065
lipid metabolic process GO:0006629 381 0.065
regulation of ribosome biogenesis GO:0090069 1 0.064
regulation of protein kinase activity GO:0045859 289 0.063
neurogenesis GO:0022008 169 0.062
positive regulation of cellular component biogenesis GO:0044089 158 0.061
cell projection assembly GO:0030031 126 0.060
organonitrogen compound biosynthetic process GO:1901566 200 0.060
oxidation reduction process GO:0055114 396 0.060
regulation of transferase activity GO:0051338 355 0.060
single organism cellular localization GO:1902580 332 0.060
neuron differentiation GO:0030182 138 0.060
regulation of protein localization GO:0032880 296 0.060
positive regulation of organelle organization GO:0010638 195 0.059
cytoplasmic transport GO:0016482 379 0.059
regulation of reactive oxygen species metabolic process GO:2000377 41 0.059
cation transport GO:0006812 331 0.058
protein polymerization GO:0051258 71 0.058
determination of adult lifespan GO:0008340 2 0.056
regulation of nucleoside metabolic process GO:0009118 209 0.055
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 144 0.054
Mouse
growth GO:0040007 202 0.054
regulation of actin filament based process GO:0032970 141 0.054
somatic muscle development GO:0007525 1 0.054
actin filament polymerization GO:0030041 45 0.053
negative regulation of cellular amine metabolic process GO:0033239 3 0.053
negative regulation of catalytic activity GO:0043086 335 0.053
fatty acid catabolic process GO:0009062 29 0.053
carbohydrate metabolic process GO:0005975 207 0.053
neuron development GO:0048666 113 0.052
response to organonitrogen compound GO:0010243 156 0.051
negative regulation of cellular protein metabolic process GO:0032269 353 0.051
sphingolipid metabolic process GO:0006665 38 0.051
dephosphorylation GO:0016311 209 0.051
endosomal transport GO:0016197 129 0.051
regulation of cell projection organization GO:0031344 107 0.050
organic acid catabolic process GO:0016054 71 0.050
transcription from rna polymerase iii promoter GO:0006383 19 0.050
actin filament organization GO:0007015 128 0.049
regulation of immune response GO:0050776 201 0.048
positive regulation of protein kinase activity GO:0045860 190 0.048
lipid modification GO:0030258 84 0.048
positive regulation of nucleoside metabolic process GO:0045979 186 0.048
Human Mouse
regulation of cell motility GO:2000145 299 0.048
cellular lipid metabolic process GO:0044255 303 0.047
cell activation GO:0001775 213 0.047
Mouse
regulation of establishment of protein localization GO:0070201 242 0.047
mitotic cell cycle GO:0000278 326 0.046
cell projection morphogenesis GO:0048858 129 0.046
response to oxygen containing compound GO:1901700 369 0.046
endocytic recycling GO:0032456 12 0.045
regulation of rac gtpase activity GO:0032314 4 0.045
regulation of protein complex assembly GO:0043254 147 0.044
regulation of response to external stimulus GO:0032101 222 0.044
anion transport GO:0006820 161 0.044
system process GO:0003008 349 0.043
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.043
regulation of actin cytoskeleton organization GO:0032956 116 0.043
negative regulation of protein phosphorylation GO:0001933 140 0.042
positive regulation of actin filament polymerization GO:0030838 38 0.042
protein ubiquitination GO:0016567 314 0.042
positive regulation of cytoskeleton organization GO:0051495 83 0.042
regulation of anatomical structure morphogenesis GO:0022603 286 0.041
Mouse
biological adhesion GO:0022610 331 0.041
Mouse
response to extracellular stimulus GO:0009991 85 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.041
Human Mouse
mitotic cell cycle process GO:1903047 286 0.040
response to nitrogen compound GO:1901698 184 0.040
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.040
intracellular protein transport GO:0006886 270 0.040
transmission of nerve impulse GO:0019226 11 0.040
single organism carbohydrate metabolic process GO:0044723 193 0.039
regulation of cell growth GO:0001558 135 0.039
neurological system process GO:0050877 163 0.039
small molecule catabolic process GO:0044282 92 0.039
actin polymerization or depolymerization GO:0008154 56 0.039
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.039
negative regulation of transferase activity GO:0051348 124 0.039
immune response GO:0006955 307 0.038
positive regulation of transport GO:0051050 336 0.038
cell growth GO:0016049 160 0.038
positive regulation of transferase activity GO:0051347 227 0.038
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.038
regulation of fatty acid beta oxidation GO:0031998 8 0.038
regulation of lipid catabolic process GO:0050994 23 0.037
negative regulation of kinase activity GO:0033673 106 0.037
reactive oxygen species metabolic process GO:0072593 75 0.037
Mouse
negative regulation of hydrolase activity GO:0051346 182 0.037
lipid catabolic process GO:0016042 84 0.036
regulation of cell migration GO:0030334 289 0.036
response to cytokine GO:0034097 232 0.036
regulation of growth GO:0040008 165 0.036
regulation of actin polymerization or depolymerization GO:0008064 56 0.036
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.036
Human Mouse
regulation of phosphatase activity GO:0010921 81 0.036
single organism membrane organization GO:0044802 268 0.036
lipid localization GO:0010876 106 0.035
regulation of cytoskeleton organization GO:0051493 177 0.035
regulation of cytoplasmic transport GO:1903649 149 0.035
circulatory system development GO:0072359 262 0.034
divalent metal ion transport GO:0070838 152 0.034
protein localization to organelle GO:0033365 280 0.034
lipid oxidation GO:0034440 33 0.034
positive regulation of protein polymerization GO:0032273 45 0.033
regulation of protein transport GO:0051223 213 0.033
response to food GO:0032094 1 0.033
actin filament bundle organization GO:0061572 54 0.033
positive regulation of myotube differentiation GO:0010831 3 0.033
leukocyte activation GO:0045321 164 0.032
Mouse
g1 s transition of mitotic cell cycle GO:0000082 78 0.032
monocarboxylic acid metabolic process GO:0032787 185 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
Human Mouse
response to radiation GO:0009314 151 0.032
cellular response to nutrient levels GO:0031669 69 0.031
positive regulation of nucleotide catabolic process GO:0030813 185 0.031
Human Mouse
positive regulation of kinase activity GO:0033674 204 0.031
regulation of intracellular transport GO:0032386 195 0.031
cellular response to external stimulus GO:0071496 111 0.031
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.031
negative regulation of nfat protein import into nucleus GO:0051534 2 0.031
regulation of protein serine threonine kinase activity GO:0071900 179 0.031
protein localization to membrane GO:0072657 160 0.030
regulation of dephosphorylation GO:0035303 96 0.030
positive regulation of protein complex assembly GO:0031334 86 0.030
regulation of actin filament length GO:0030832 56 0.030
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.030
positive regulation of epithelial cell proliferation GO:0050679 65 0.030
nucleocytoplasmic transport GO:0006913 176 0.030
cellular ion homeostasis GO:0006873 168 0.030
endomembrane system organization GO:0010256 196 0.030
negative regulation of intracellular signal transduction GO:1902532 183 0.030
membrane lipid biosynthetic process GO:0046467 27 0.029
ion transmembrane transport GO:0034220 338 0.029
maintenance of location GO:0051235 112 0.029
cellular cation homeostasis GO:0030003 163 0.029
positive regulation of cell differentiation GO:0045597 211 0.029
Mouse
myoblast fusion GO:0007520 1 0.028
muscle contraction GO:0006936 73 0.028
cell part morphogenesis GO:0032990 137 0.028
oogenesis GO:0048477 2 0.028
negative regulation of phosphatase activity GO:0010923 61 0.028
regulation of myelination GO:0031641 1 0.028
regulation of cell morphogenesis GO:0022604 153 0.028
Mouse
monocarboxylic acid catabolic process GO:0072329 37 0.028
cellular polysaccharide biosynthetic process GO:0033692 21 0.028
regulation of vesicle mediated transport GO:0060627 130 0.027
lymphocyte activation GO:0046649 133 0.027
Mouse
regeneration GO:0031099 4 0.027
membrane organization GO:0061024 292 0.027
positive regulation of ras gtpase activity GO:0032320 117 0.027
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 175 0.027
regulation of cell development GO:0060284 161 0.027
Mouse
autophagy GO:0006914 88 0.027
positive regulation of cell migration GO:0030335 172 0.026
negative regulation of protein modification process GO:0031400 200 0.026
response to light stimulus GO:0009416 87 0.026
positive regulation of hydrolase activity GO:0051345 331 0.026
Human Mouse
multicellular organismal signaling GO:0035637 34 0.026
endothelial cell proliferation GO:0001935 65 0.026
positive regulation of immune system process GO:0002684 283 0.026
response to nutrient levels GO:0031667 81 0.025
anatomical structure homeostasis GO:0060249 100 0.025
response to abiotic stimulus GO:0009628 336 0.025
regulation of mapk cascade GO:0043408 262 0.025
endocytosis GO:0006897 159 0.025
protein modification by small protein conjugation GO:0032446 342 0.025
metal ion transport GO:0030001 272 0.025
vasculature development GO:0001944 181 0.025
cell chemotaxis GO:0060326 112 0.025
Mouse
regulation of transcription from rna polymerase iii promoter GO:0006359 13 0.025
positive regulation of gtp catabolic process GO:0033126 166 0.025
Human Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
negative regulation of cellular catabolic process GO:0031330 83 0.024
organic anion transport GO:0015711 103 0.024
cell adhesion GO:0007155 325 0.024
Mouse
muscle structure development GO:0061061 98 0.024
ribonucleoprotein complex biogenesis GO:0022613 116 0.024
regulation of protein polymerization GO:0032271 63 0.023
protein targeting GO:0006605 187 0.023
cellular carbohydrate metabolic process GO:0044262 84 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
carboxylic acid catabolic process GO:0046395 71 0.023
actin filament bundle assembly GO:0051017 54 0.023
positive regulation of vasoconstriction GO:0045907 3 0.023
peripheral nervous system development GO:0007422 2 0.022
regulation of intracellular protein transport GO:0033157 123 0.022
monosaccharide metabolic process GO:0005996 74 0.022
positive regulation of developmental process GO:0051094 314 0.022
Mouse
regulation of lipid biosynthetic process GO:0046890 47 0.022
g protein coupled receptor signaling pathway GO:0007186 207 0.022
Human Mouse
organelle fission GO:0048285 149 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
neuronal action potential GO:0019228 9 0.022
protein import into nucleus GO:0006606 104 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
cell cycle g1 s phase transition GO:0044843 80 0.021
positive regulation of lipid biosynthetic process GO:0046889 22 0.021
regulation of metal ion transport GO:0010959 120 0.021
female gamete generation GO:0007292 2 0.021
translation GO:0006412 132 0.021
nuclear transport GO:0051169 179 0.021
defense response GO:0006952 315 0.021
regulation of nervous system development GO:0051960 88 0.021
positive regulation of lamellipodium assembly GO:0010592 9 0.021
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.021
extrinsic apoptotic signaling pathway GO:0097191 119 0.021
action potential GO:0001508 34 0.021
positive regulation of cell death GO:0010942 263 0.021
carboxylic acid transport GO:0046942 63 0.021
protein import GO:0017038 130 0.021
regulation of actin filament bundle assembly GO:0032231 36 0.021
immune response regulating signaling pathway GO:0002764 97 0.020
positive regulation of cellular component movement GO:0051272 181 0.020
positive regulation of gtpase activity GO:0043547 166 0.020
Human Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.020
regulation of neurogenesis GO:0050767 82 0.020
macroautophagy GO:0016236 39 0.020
hexose metabolic process GO:0019318 55 0.020
lamellipodium organization GO:0097581 30 0.020
peptidyl serine modification GO:0018209 106 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
neuron projection morphogenesis GO:0048812 50 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
positive regulation of cell proliferation GO:0008284 301 0.020
cellular biogenic amine metabolic process GO:0006576 34 0.020
transmembrane transport GO:0055085 399 0.020
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
negative regulation of developmental process GO:0051093 247 0.019
divalent inorganic cation transport GO:0072511 158 0.019
response to starvation GO:0042594 59 0.019
cellular response to nitrogen compound GO:1901699 144 0.019
regulation of epithelial cell proliferation GO:0050678 113 0.019
regulation of neuron differentiation GO:0045664 70 0.019
single organism nuclear import GO:1902593 104 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
Human Mouse
locomotory behavior GO:0007626 1 0.019
stress fiber assembly GO:0043149 40 0.019
hindbrain development GO:0030902 3 0.019
neuron projection regeneration GO:0031102 1 0.019
response to hormone GO:0009725 175 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
cell cycle phase transition GO:0044770 173 0.019
negative regulation of organelle organization GO:0010639 126 0.019
protein localization to nucleus GO:0034504 136 0.018
positive regulation of cell projection organization GO:0031346 64 0.018
blastoderm segmentation GO:0007350 2 0.018
response to axon injury GO:0048678 1 0.018
chemical homeostasis GO:0048878 306 0.018
regulation of nucleocytoplasmic transport GO:0046822 98 0.018
compound eye development GO:0048749 1 0.018
regulation of lipid metabolic process GO:0019216 96 0.018
regulation of neuron projection development GO:0010975 57 0.018
segmentation GO:0035282 4 0.018
response to organic cyclic compound GO:0014070 204 0.018
negative regulation of catabolic process GO:0009895 104 0.018
protein targeting to nucleus GO:0044744 104 0.018
regulation of glycogen metabolic process GO:0070873 15 0.018
epithelial cell proliferation GO:0050673 128 0.018
regulation of ion transport GO:0043269 189 0.017
brain development GO:0007420 97 0.017
carbohydrate biosynthetic process GO:0016051 42 0.017
glycogen metabolic process GO:0005977 22 0.017
cellular carbohydrate biosynthetic process GO:0034637 21 0.017
regulation of ion transmembrane transport GO:0034765 132 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
t cell activation GO:0042110 99 0.017
Mouse
secretion GO:0046903 254 0.017
sequestering of metal ion GO:0051238 24 0.017
termination of signal transduction GO:0023021 3 0.017
regulation of axon regeneration GO:0048679 1 0.017
mononuclear cell proliferation GO:0032943 71 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
regulation of cell projection assembly GO:0060491 47 0.017
cellular response to starvation GO:0009267 58 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
cellular response to hypoxia GO:0071456 51 0.016
cellular response to peptide GO:1901653 59 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
nitrogen compound transport GO:0071705 191 0.016
regulation of membrane potential GO:0042391 95 0.016
regulation of generation of precursor metabolites and energy GO:0043467 27 0.016
negative regulation of protein transport GO:0051224 75 0.016
sphingolipid biosynthetic process GO:0030148 18 0.016
adult locomotory behavior GO:0008344 1 0.016
response to hypoxia GO:0001666 96 0.016
negative regulation of cytoplasmic transport GO:1903650 46 0.016
sensory perception GO:0007600 103 0.016
actomyosin structure organization GO:0031032 59 0.016
regulation of response to drug GO:2001023 3 0.016
regulation of cell cycle GO:0051726 393 0.016
protein autophosphorylation GO:0046777 123 0.016
response to oxygen levels GO:0070482 100 0.016
plasma membrane organization GO:0007009 115 0.016
protein maturation GO:0051604 233 0.016
positive regulation of transcription from rna polymerase iii promoter GO:0045945 10 0.016
cellular response to decreased oxygen levels GO:0036294 51 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
positive regulation of lipid metabolic process GO:0045834 50 0.016
peptidyl threonine phosphorylation GO:0018107 41 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
cation transmembrane transport GO:0098655 238 0.016
innate immune response GO:0045087 178 0.016
i kappab kinase nf kappab signaling GO:0007249 166 0.016
cardiovascular system development GO:0072358 262 0.016
chromatin organization GO:0006325 351 0.016
phospholipid catabolic process GO:0009395 12 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
protein catabolic process GO:0030163 325 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
cellular protein catabolic process GO:0044257 261 0.015
regulation of cellular response to stress GO:0080135 244 0.015
regulation of neuron projection regeneration GO:0070570 1 0.015
negative regulation of synaptic transmission GO:0050805 2 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
glycogen biosynthetic process GO:0005978 16 0.015
negative regulation of protein kinase activity GO:0006469 98 0.015
negative regulation of locomotion GO:0040013 118 0.015
nuclear import GO:0051170 106 0.015
regulation of cell adhesion GO:0030155 166 0.015
Mouse
phospholipid metabolic process GO:0006644 99 0.015
organic acid transport GO:0015849 65 0.015
regulation of protein targeting GO:1903533 91 0.015
regulation of protein localization to nucleus GO:1900180 85 0.015
calcium ion transport GO:0006816 147 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
protein localization to plasma membrane GO:0072659 93 0.015
establishment or maintenance of actin cytoskeleton polarity GO:0030950 1 0.015
microtubule based process GO:0007017 210 0.015
ameboidal type cell migration GO:0001667 135 0.015
nerve development GO:0021675 4 0.015
rna processing GO:0006396 255 0.015
calcium ion transmembrane transport GO:0070588 76 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
regulation of endothelial cell proliferation GO:0001936 56 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
cellular response to extracellular stimulus GO:0031668 72 0.015
head development GO:0060322 108 0.015
blood vessel morphogenesis GO:0048514 162 0.015
negative regulation of tor signaling GO:0032007 11 0.015
epithelium development GO:0060429 227 0.014
cation homeostasis GO:0055080 189 0.014
cytokine production GO:0001816 247 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
positive regulation of translation GO:0045727 35 0.014
monovalent inorganic cation transport GO:0015672 128 0.014
generation of precursor metabolites and energy GO:0006091 68 0.014
embryo development GO:0009790 123 0.014
secretion by cell GO:0032940 226 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
fatty acid metabolic process GO:0006631 115 0.014
negative regulation of protein localization to nucleus GO:1900181 34 0.014
cellular divalent inorganic cation homeostasis GO:0072503 128 0.014
protein kinase b signaling GO:0043491 69 0.014
positive regulation of immune response GO:0050778 159 0.014
mrna metabolic process GO:0016071 175 0.014
regulation of leukocyte activation GO:0002694 115 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
positive regulation of locomotion GO:0040017 186 0.014
regulation of protein kinase b signaling GO:0051896 61 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
glucose metabolic process GO:0006006 45 0.014
organelle assembly GO:0070925 176 0.014
alcohol metabolic process GO:0006066 114 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
regulation of lamellipodium assembly GO:0010591 14 0.014
cdc42 protein signal transduction GO:0032488 4 0.013
associative learning GO:0008306 1 0.013
ribosome biogenesis GO:0042254 48 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
cellular polysaccharide metabolic process GO:0044264 27 0.013
cerebellum development GO:0021549 2 0.013
salivary gland morphogenesis GO:0007435 4 0.013
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.013
regulation of dna metabolic process GO:0051052 153 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
regulation of endocytosis GO:0030100 72 0.013
negative regulation of dephosphorylation GO:0035305 63 0.013
regulation of transmembrane transporter activity GO:0022898 74 0.013
regulation of transmembrane transport GO:0034762 139 0.013
apoptotic signaling pathway GO:0097190 268 0.013

PREX1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.019
disease of cellular proliferation DOID:14566 174 0.016
cancer DOID:162 167 0.015
organ system cancer DOID:0050686 164 0.015
inherited metabolic disorder DOID:655 242 0.015
sensory system disease DOID:0050155 203 0.014
nervous system disease DOID:863 431 0.014
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013