Homo sapiens

19 known processes

PPME1

protein phosphatase methylesterase 1

(Aliases: PME-1,FLJ22226)

PPME1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.268
modification dependent protein catabolic process GO:0019941 209 0.218
cellular macromolecule catabolic process GO:0044265 380 0.200
protein dephosphorylation GO:0006470 81 0.182
modification dependent macromolecule catabolic process GO:0043632 212 0.166
dephosphorylation GO:0016311 209 0.154
neuronal stem cell division GO:0036445 1 0.154
neuroblast division GO:0055057 1 0.140
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.140
neuroblast proliferation GO:0007405 4 0.132
regulation of mitotic cell cycle GO:0007346 189 0.129
mitotic cell cycle process GO:1903047 286 0.127
regulation of neuroblast proliferation GO:1902692 3 0.126
ubiquitin dependent protein catabolic process GO:0006511 206 0.122
regulation of neural precursor cell proliferation GO:2000177 4 0.117
negative regulation of mitotic cell cycle GO:0045930 102 0.110
cell cycle phase transition GO:0044770 173 0.110
regulation of cell cycle GO:0051726 393 0.109
proteasomal protein catabolic process GO:0010498 176 0.106
mitotic cell cycle GO:0000278 326 0.103
cellular protein catabolic process GO:0044257 261 0.102
protein catabolic process GO:0030163 325 0.093
purine ribonucleoside metabolic process GO:0046128 437 0.087
wnt signaling pathway GO:0016055 156 0.082
oogenesis GO:0048477 2 0.080
regulation of protein localization GO:0032880 296 0.080
cell cycle checkpoint GO:0000075 117 0.079
asymmetric neuroblast division GO:0055059 1 0.078
negative regulation of cellular component organization GO:0051129 235 0.078
regulation of cell cycle phase transition GO:1901987 126 0.076
somatic stem cell division GO:0048103 1 0.075
negative regulation of protein processing GO:0010955 142 0.074
protein maturation GO:0051604 233 0.074
asymmetric stem cell division GO:0098722 1 0.071
stem cell division GO:0017145 2 0.071
mitotic cell cycle phase transition GO:0044772 162 0.069
female gamete generation GO:0007292 2 0.068
negative regulation of cell cycle phase transition GO:1901988 89 0.068
regulation of proteasomal protein catabolic process GO:0061136 87 0.068
mitotic cell cycle checkpoint GO:0007093 68 0.067
protein localization to organelle GO:0033365 280 0.061
cellular amino acid metabolic process GO:0006520 116 0.059
organelle assembly GO:0070925 176 0.058
microtubule cytoskeleton organization GO:0000226 176 0.055
single organism membrane organization GO:0044802 268 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
negative regulation of developmental process GO:0051093 247 0.054
negative regulation of multicellular organismal process GO:0051241 317 0.054
nervous system development GO:0007399 293 0.054
cell development GO:0048468 328 0.053
regulation of protein maturation GO:1903317 150 0.052
negative regulation of cell cycle process GO:0010948 121 0.052
mitotic sister chromatid segregation GO:0000070 53 0.051
post embryonic development GO:0009791 2 0.051
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.051
chemical homeostasis GO:0048878 306 0.051
regulation of mitotic cell cycle phase transition GO:1901990 118 0.050
cellular protein complex assembly GO:0043623 188 0.050
microtubule based process GO:0007017 210 0.050
negative regulation of catalytic activity GO:0043086 335 0.049
regulation of cell cycle process GO:0010564 266 0.049
cellular component morphogenesis GO:0032989 314 0.049
protein processing GO:0016485 226 0.048
generation of neurons GO:0048699 152 0.048
neuromuscular junction development GO:0007528 3 0.047
multicellular organismal aging GO:0010259 3 0.047
negative regulation of cellular protein metabolic process GO:0032269 353 0.047
single organism cellular localization GO:1902580 332 0.047
purine nucleoside catabolic process GO:0006152 398 0.046
regulation of transferase activity GO:0051338 355 0.046
regulation of establishment of protein localization GO:0070201 242 0.045
cytoplasmic transport GO:0016482 379 0.045
defense response GO:0006952 315 0.044
regulation of protein processing GO:0070613 150 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
negative regulation of phosphorus metabolic process GO:0010563 267 0.043
purine ribonucleotide catabolic process GO:0009154 404 0.043
cell cell signaling GO:0007267 155 0.043
response to oxygen containing compound GO:1901700 369 0.043
negative regulation of protein maturation GO:1903318 142 0.043
negative regulation of protein metabolic process GO:0051248 391 0.042
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
purine nucleoside triphosphate catabolic process GO:0009146 392 0.042
negative regulation of proteolysis GO:0045861 132 0.042
regeneration GO:0031099 4 0.042
cellular response to dna damage stimulus GO:0006974 379 0.042
chromosome segregation GO:0007059 114 0.041
regulation of proteolysis GO:0030162 293 0.040
nucleoside triphosphate catabolic process GO:0009143 394 0.039
regulation of cell division GO:0051302 116 0.039
nuclear division GO:0000280 128 0.039
single organism carbohydrate metabolic process GO:0044723 193 0.039
establishment or maintenance of neuroblast polarity GO:0045196 1 0.039
segmentation GO:0035282 4 0.039
determination of adult lifespan GO:0008340 2 0.039
amine metabolic process GO:0009308 44 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.038
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.038
membrane organization GO:0061024 292 0.037
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.037
negative regulation of phosphorylation GO:0042326 174 0.037
regulation of kinase activity GO:0043549 314 0.036
negative regulation of phosphate metabolic process GO:0045936 267 0.036
nucleotide catabolic process GO:0009166 408 0.036
negative regulation of cell cycle GO:0045786 193 0.036
cell morphogenesis GO:0000902 296 0.036
negative regulation of chromosome organization GO:2001251 48 0.035
purine nucleotide catabolic process GO:0006195 405 0.035
purine ribonucleoside catabolic process GO:0046130 398 0.034
negative regulation of cell differentiation GO:0045596 171 0.034
regulation of cell differentiation GO:0045595 393 0.034
ribonucleoside catabolic process GO:0042454 406 0.034
purine containing compound catabolic process GO:0072523 411 0.034
regulation of protein catabolic process GO:0042176 155 0.034
lipid metabolic process GO:0006629 381 0.034
posttranscriptional regulation of gene expression GO:0010608 213 0.034
positive regulation of hydrolase activity GO:0051345 331 0.033
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.033
glycosyl compound catabolic process GO:1901658 413 0.033
chromosome separation GO:0051304 23 0.033
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
cellular amine metabolic process GO:0044106 41 0.032
positive regulation of catabolic process GO:0009896 310 0.032
negative regulation of cell proliferation GO:0008285 228 0.032
carbohydrate metabolic process GO:0005975 207 0.032
neurogenesis GO:0022008 169 0.032
mitochondrion organization GO:0007005 156 0.032
negative regulation of organelle organization GO:0010639 126 0.032
intrinsic apoptotic signaling pathway GO:0097193 127 0.032
axon regeneration GO:0031103 1 0.032
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.032
cell projection organization GO:0030030 252 0.031
positive regulation of transport GO:0051050 336 0.031
regulation of cell motility GO:2000145 299 0.031
mitotic nuclear division GO:0007067 119 0.031
organophosphate catabolic process GO:0046434 430 0.031
regulation of dephosphorylation GO:0035303 96 0.031
mitotic sister chromatid separation GO:0051306 18 0.031
apoptotic signaling pathway GO:0097190 268 0.031
cellular homeostasis GO:0019725 196 0.030
oocyte differentiation GO:0009994 2 0.030
sister chromatid segregation GO:0000819 54 0.030
vesicle mediated transport GO:0016192 371 0.030
oocyte development GO:0048599 1 0.030
protein localization to nucleus GO:0034504 136 0.029
mitotic spindle assembly checkpoint GO:0007094 14 0.029
cell division GO:0051301 168 0.028
cellular ketone metabolic process GO:0042180 80 0.028
cation transport GO:0006812 331 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
regulation of cellular ketone metabolic process GO:0010565 50 0.028
protein targeting GO:0006605 187 0.028
regulation of cell migration GO:0030334 289 0.028
endomembrane system organization GO:0010256 196 0.028
ribonucleotide catabolic process GO:0009261 405 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
locomotory behavior GO:0007626 1 0.028
covalent chromatin modification GO:0016569 254 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
negative regulation of stem cell proliferation GO:2000647 3 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
regulation of secretion by cell GO:1903530 177 0.027
g2 m transition of mitotic cell cycle GO:0000086 41 0.027
nucleoside catabolic process GO:0009164 408 0.026
positive regulation of protein phosphorylation GO:0001934 313 0.026
chromatin organization GO:0006325 351 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
regulation of cellular protein catabolic process GO:1903362 96 0.026
negative regulation of protein catabolic process GO:0042177 59 0.026
negative regulation of catabolic process GO:0009895 104 0.026
autophagy GO:0006914 88 0.026
regulation of mitotic sister chromatid segregation GO:0033047 27 0.026
regulation of protein localization to nucleus GO:1900180 85 0.026
response to other organism GO:0051707 261 0.025
positive regulation of cell cycle process GO:0090068 106 0.025
secretion by cell GO:0032940 226 0.025
response to external biotic stimulus GO:0043207 261 0.025
regulation of cell development GO:0060284 161 0.025
oxidation reduction process GO:0055114 396 0.025
gtp metabolic process GO:0046039 239 0.025
ribonucleoside monophosphate metabolic process GO:0009161 187 0.025
negative regulation of cell death GO:0060548 345 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
actin filament based process GO:0030029 224 0.024
regulation of protein stability GO:0031647 87 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
nitrogen compound transport GO:0071705 191 0.024
positive regulation of cell cycle GO:0045787 140 0.024
guanosine containing compound catabolic process GO:1901069 239 0.024
small molecule biosynthetic process GO:0044283 157 0.023
somitogenesis GO:0001756 2 0.023
regulation of chromosome organization GO:0033044 103 0.023
regulation of chromosome segregation GO:0051983 44 0.023
negative regulation of cellular catabolic process GO:0031330 83 0.023
spindle assembly checkpoint GO:0071173 17 0.023
negative regulation of protein modification process GO:0031400 200 0.023
neuron projection development GO:0031175 106 0.023
organelle fission GO:0048285 149 0.023
spindle checkpoint GO:0031577 26 0.022
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
cellular chemical homeostasis GO:0055082 180 0.022
negative regulation of cellular protein catabolic process GO:1903363 38 0.022
response to abiotic stimulus GO:0009628 336 0.022
regulation of sister chromatid segregation GO:0033045 27 0.022
apoptotic process involved in morphogenesis GO:0060561 3 0.022
somatic muscle development GO:0007525 1 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
ras protein signal transduction GO:0007265 73 0.022
regulation of growth GO:0040008 165 0.022
circulatory system development GO:0072359 262 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
negative regulation of kinase activity GO:0033673 106 0.021
carbohydrate derivative biosynthetic process GO:1901137 207 0.021
gtp catabolic process GO:0006184 237 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
regulation of nervous system development GO:0051960 88 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
guanosine containing compound metabolic process GO:1901068 244 0.021
axon cargo transport GO:0008088 2 0.021
biological adhesion GO:0022610 331 0.021
spermatid differentiation GO:0048515 4 0.021
protein ubiquitination GO:0016567 314 0.021
negative regulation of cytokinesis GO:0032466 3 0.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.020
establishment of nucleus localization GO:0040023 1 0.020
maintenance of cell polarity GO:0030011 2 0.020
negative regulation of neural precursor cell proliferation GO:2000178 1 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
regulation of gtpase activity GO:0043087 180 0.020
dna integrity checkpoint GO:0031570 71 0.019
regulation of protein kinase activity GO:0045859 289 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
regulation of cellular response to stress GO:0080135 244 0.019
negative regulation of transport GO:0051051 176 0.019
actin cytoskeleton organization GO:0030036 207 0.019
canonical wnt signaling pathway GO:0060070 116 0.019
reproductive process GO:0022414 106 0.019
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.019
regulation of locomotion GO:0040012 329 0.019
mitotic spindle checkpoint GO:0071174 18 0.019
negative regulation of sister chromatid segregation GO:0033046 17 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
purine nucleoside monophosphate catabolic process GO:0009128 158 0.018
thymus development GO:0048538 3 0.018
centrosome organization GO:0051297 58 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
nuclear migration GO:0007097 1 0.018
negative regulation of locomotion GO:0040013 118 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
memory GO:0007613 3 0.018
regulation of protein transport GO:0051223 213 0.018
system process GO:0003008 349 0.018
negative regulation of transferase activity GO:0051348 124 0.018
chemotaxis GO:0006935 157 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
intracellular protein transport GO:0006886 270 0.017
regulation of response to external stimulus GO:0032101 222 0.017
negative regulation of cell division GO:0051782 31 0.017
embryo development GO:0009790 123 0.017
protein stabilization GO:0050821 64 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
microtubule organizing center organization GO:0031023 62 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
spermatid development GO:0007286 4 0.017
metaphase anaphase transition of cell cycle GO:0044784 21 0.017
centriole replication GO:0007099 13 0.017
regulation of secretion GO:0051046 194 0.017
nucleus localization GO:0051647 1 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
metal ion transport GO:0030001 272 0.017
positive regulation of transferase activity GO:0051347 227 0.017
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.016
response to biotic stimulus GO:0009607 276 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
interspecies interaction between organisms GO:0044419 156 0.016
rna interference GO:0016246 4 0.016
regulation of dna metabolic process GO:0051052 153 0.016
vasodilation GO:0042311 4 0.016
response to oxidative stress GO:0006979 121 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
regulation of canonical wnt signaling pathway GO:0060828 88 0.016
protein autophosphorylation GO:0046777 123 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
regulation of mapk cascade GO:0043408 262 0.016
regulation of cell cycle g1 s phase transition GO:1902806 42 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
positive regulation of protein localization to nucleus GO:1900182 48 0.016
cell cycle g2 m phase transition GO:0044839 43 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
negative regulation of lipid metabolic process GO:0045833 38 0.016
positive regulation of cell death GO:0010942 263 0.016
positive regulation of developmental process GO:0051094 314 0.016
chromatin modification GO:0016568 298 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
negative regulation of mitosis GO:0045839 24 0.015
cellular lipid metabolic process GO:0044255 303 0.015
organic acid biosynthetic process GO:0016053 97 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
neuron differentiation GO:0030182 138 0.015
myosin filament assembly GO:0031034 2 0.015
neuron projection regeneration GO:0031102 1 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
rab protein signal transduction GO:0032482 4 0.015
neurotransmitter secretion GO:0007269 4 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
neuron development GO:0048666 113 0.015
multi organism reproductive process GO:0044703 54 0.015
maintenance of location GO:0051235 112 0.015
protein localization to membrane GO:0072657 160 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
positive regulation of kinase activity GO:0033674 204 0.015
lipid biosynthetic process GO:0008610 177 0.015
regulation of multi organism process GO:0043900 157 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
g1 dna damage checkpoint GO:0044783 18 0.015
regulation of neuron projection regeneration GO:0070570 1 0.015
peripheral nervous system development GO:0007422 2 0.014
cell part morphogenesis GO:0032990 137 0.014
regulation of translation GO:0006417 89 0.014
secretion GO:0046903 254 0.014
actin filament organization GO:0007015 128 0.014
organelle localization GO:0051640 84 0.014
positive regulation of protein dephosphorylation GO:0035307 16 0.014
anterior posterior axis specification GO:0009948 2 0.014
carboxylic acid biosynthetic process GO:0046394 97 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.014
single organism nuclear import GO:1902593 104 0.014
protein secretion GO:0009306 98 0.014
atp metabolic process GO:0046034 176 0.014
regulation of peptidase activity GO:0052547 180 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
response to axon injury GO:0048678 1 0.014
mating GO:0007618 1 0.014
eye photoreceptor cell differentiation GO:0001754 2 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
organ formation GO:0048645 3 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
adult locomotory behavior GO:0008344 1 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
protein oligomerization GO:0051259 173 0.014
dna damage checkpoint GO:0000077 68 0.014
response to fungus GO:0009620 4 0.014
immune effector process GO:0002252 159 0.014
dna repair GO:0006281 198 0.014
growth GO:0040007 202 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
alcohol metabolic process GO:0006066 114 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
regulation of cellular component movement GO:0051270 334 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
g1 s transition of mitotic cell cycle GO:0000082 78 0.013
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.013
cytokinesis GO:0000910 96 0.013
rhythmic behavior GO:0007622 2 0.013
regulation of oocyte development GO:0060281 1 0.013
membrane hyperpolarization GO:0060081 1 0.013
negative regulation of cell development GO:0010721 48 0.013
circadian behavior GO:0048512 2 0.013
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
cell adhesion GO:0007155 325 0.013
epithelium development GO:0060429 227 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
extrinsic apoptotic signaling pathway GO:0097191 119 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
response to radiation GO:0009314 151 0.013
histone modification GO:0016570 251 0.013
meiosis i GO:0007127 4 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.013
lipid transport GO:0006869 90 0.013
divalent metal ion transport GO:0070838 152 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.013
cardiovascular system development GO:0072358 262 0.013
glycoprotein metabolic process GO:0009100 110 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
positive regulation of ras gtpase activity GO:0032320 117 0.013
axis elongation GO:0003401 4 0.013
nucleocytoplasmic transport GO:0006913 176 0.012
cell projection morphogenesis GO:0048858 129 0.012
response to lipid GO:0033993 206 0.012
transmembrane transport GO:0055085 399 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
regulation of map kinase activity GO:0043405 108 0.012
regulation of transporter activity GO:0032409 82 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
reproduction GO:0000003 63 0.012
cell cycle g1 s phase transition GO:0044843 80 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
protein targeting to nucleus GO:0044744 104 0.012
cell morphogenesis involved in differentiation GO:0000904 144 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
protein localization to plasma membrane GO:0072659 93 0.012
single organism reproductive process GO:0044702 98 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
rho protein signal transduction GO:0007266 26 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
positive regulation of protein transport GO:0051222 135 0.012
metencephalon development GO:0022037 2 0.012
signal transduction by p53 class mediator GO:0072331 72 0.012
regulation of growth of symbiont in host GO:0044126 1 0.012
blastoderm segmentation GO:0007350 2 0.012
synaptic transmission GO:0007268 61 0.012
anion transport GO:0006820 161 0.012
response to nitrogen compound GO:1901698 184 0.012
spindle elongation GO:0051231 4 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.011
viral life cycle GO:0019058 132 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
immune response GO:0006955 307 0.011
negative regulation of synaptic transmission GO:0050805 2 0.011
regulation of neurogenesis GO:0050767 82 0.011
mitotic dna integrity checkpoint GO:0044774 30 0.011
nuclear import GO:0051170 106 0.011
growth hormone secretion GO:0030252 4 0.011
regulation of chemotaxis GO:0050920 74 0.011
inner ear morphogenesis GO:0042472 4 0.011
cell cycle arrest GO:0007050 71 0.011
positive regulation of cell cycle arrest GO:0071158 23 0.011
regulation of axon guidance GO:1902667 3 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
myosin filament organization GO:0031033 2 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
positive regulation of vasoconstriction GO:0045907 3 0.011
compound eye development GO:0048749 1 0.011
nerve development GO:0021675 4 0.011
behavior GO:0007610 112 0.011
regulation of cytokinesis GO:0032465 45 0.011
cellular response to lipid GO:0071396 127 0.011
positive regulation of secretion GO:0051047 116 0.011
mapk cascade GO:0000165 288 0.011
regulation of meiosis GO:0040020 3 0.011
regulation of intracellular transport GO:0032386 195 0.011
regulation of actin filament based process GO:0032970 141 0.011
negative regulation of peptidase activity GO:0010466 91 0.011
response to organic cyclic compound GO:0014070 204 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
protein import into nucleus GO:0006606 104 0.011
response to cytokine GO:0034097 232 0.011
spindle organization GO:0007051 53 0.011
cytokine production GO:0001816 247 0.011
taxis GO:0042330 157 0.011
endocytosis GO:0006897 159 0.011
myoblast fusion GO:0007520 1 0.011
negative regulation of neurogenesis GO:0050768 26 0.011
salivary gland morphogenesis GO:0007435 4 0.011
meiotic chromosome segregation GO:0045132 4 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
glycerolipid metabolic process GO:0046486 107 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
viral process GO:0016032 146 0.011
hemopoiesis GO:0030097 180 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
regulation of cell projection organization GO:0031344 107 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
negative regulation of secretion GO:0051048 58 0.010

PPME1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.024
nervous system disease DOID:863 431 0.024
musculoskeletal system disease DOID:17 223 0.020
sensory system disease DOID:0050155 203 0.017
neurodegenerative disease DOID:1289 102 0.015
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
disease of metabolism DOID:0014667 295 0.013
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
immune system disease DOID:2914 155 0.012
myopathy DOID:423 104 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
retinal disease DOID:5679 118 0.011
neuropathy DOID:870 52 0.011
bone disease DOID:0080001 88 0.011
connective tissue disease DOID:65 109 0.011
brain disease DOID:936 73 0.011