Homo sapiens

59 known processes

SYMPK

symplekin

(Aliases: FLJ27092,SPK,SYM)

SYMPK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 255 0.209
mrna processing GO:0006397 133 0.162
histone mrna 3 end processing GO:0006398 3 0.157
rna 3 end processing GO:0031123 35 0.150
mrna metabolic process GO:0016071 175 0.146
post embryonic development GO:0009791 2 0.126
mrna 3 end processing GO:0031124 24 0.081
rna interference GO:0016246 4 0.080
ras protein signal transduction GO:0007265 73 0.078
chromatin organization GO:0006325 351 0.074
covalent chromatin modification GO:0016569 254 0.062
response to biotic stimulus GO:0009607 276 0.059
multicellular organismal aging GO:0010259 3 0.055
histone modification GO:0016570 251 0.053
immune response GO:0006955 307 0.053
histone mrna metabolic process GO:0008334 13 0.052
small gtpase mediated signal transduction GO:0007264 78 0.048
vesicle mediated transport GO:0016192 371 0.047
posttranscriptional regulation of gene expression GO:0010608 213 0.046
response to other organism GO:0051707 261 0.046
chromatin modification GO:0016568 298 0.045
determination of adult lifespan GO:0008340 2 0.043
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.042
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
defense response GO:0006952 315 0.041
regulation of cell cycle GO:0051726 393 0.041
negative regulation of multicellular organismal process GO:0051241 317 0.040
regulation of gene expression epigenetic GO:0040029 73 0.039
response to abiotic stimulus GO:0009628 336 0.037
response to oxygen containing compound GO:1901700 369 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.037
response to growth factor GO:0070848 205 0.037
response to external biotic stimulus GO:0043207 261 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
cellular macromolecule catabolic process GO:0044265 380 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.035
cellular amino acid metabolic process GO:0006520 116 0.035
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
cellular response to growth factor stimulus GO:0071363 197 0.034
defense response to bacterium GO:0042742 63 0.033
locomotory behavior GO:0007626 1 0.033
amine metabolic process GO:0009308 44 0.033
organophosphate catabolic process GO:0046434 430 0.032
nervous system development GO:0007399 293 0.031
rna phosphodiester bond hydrolysis GO:0090501 35 0.031
innate immune response GO:0045087 178 0.031
positive regulation of cellular catabolic process GO:0031331 284 0.030
response to transforming growth factor beta GO:0071559 94 0.030
positive regulation of developmental process GO:0051094 314 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
cellular amine metabolic process GO:0044106 41 0.029
cellular ketone metabolic process GO:0042180 80 0.029
protein modification by small protein conjugation GO:0032446 342 0.028
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.028
regulation of mapk cascade GO:0043408 262 0.028
cellular response to endogenous stimulus GO:0071495 336 0.027
embryo development GO:0009790 123 0.027
glycosyl compound catabolic process GO:1901658 413 0.027
single organism cellular localization GO:1902580 332 0.026
negative regulation of wnt signaling pathway GO:0030178 69 0.026
response to bacterium GO:0009617 144 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
blastoderm segmentation GO:0007350 2 0.026
response to lipid GO:0033993 206 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
nucleotide catabolic process GO:0009166 408 0.025
rho protein signal transduction GO:0007266 26 0.025
wnt signaling pathway GO:0016055 156 0.025
posttranscriptional gene silencing GO:0016441 25 0.025
negative regulation of cell differentiation GO:0045596 171 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
segmentation GO:0035282 4 0.024
positive regulation of gtp catabolic process GO:0033126 166 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.023
positive regulation of immune system process GO:0002684 283 0.023
cell morphogenesis GO:0000902 296 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
defense response to other organism GO:0098542 129 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
nucleoside catabolic process GO:0009164 408 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.022
developmental process involved in reproduction GO:0003006 66 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
protein ubiquitination GO:0016567 314 0.022
negative regulation of organelle organization GO:0010639 126 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
purine containing compound catabolic process GO:0072523 411 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
protein oligomerization GO:0051259 173 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
female gamete generation GO:0007292 2 0.021
posttranscriptional gene silencing by rna GO:0035194 25 0.021
protein methylation GO:0006479 74 0.021
negative regulation of developmental process GO:0051093 247 0.021
immune system development GO:0002520 195 0.021
positive regulation of catabolic process GO:0009896 310 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
rna splicing GO:0008380 131 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
microtubule based process GO:0007017 210 0.020
cytoplasmic transport GO:0016482 379 0.020
actin filament based process GO:0030029 224 0.020
neurogenesis GO:0022008 169 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
cell fate determination GO:0001709 3 0.020
regulation of reactive oxygen species metabolic process GO:2000377 41 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
gene silencing by rna GO:0031047 26 0.020
positive regulation of hydrolase activity GO:0051345 331 0.019
dna conformation change GO:0071103 113 0.019
protein acylation GO:0043543 138 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
positive regulation of transport GO:0051050 336 0.019
histone acetylation GO:0016573 93 0.019
regulation of cell differentiation GO:0045595 393 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
dephosphorylation GO:0016311 209 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
nuclear transport GO:0051169 179 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
methylation GO:0032259 106 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
endocytosis GO:0006897 159 0.018
mitotic cell cycle process GO:1903047 286 0.018
gtp catabolic process GO:0006184 237 0.018
neuroblast proliferation GO:0007405 4 0.018
intracellular protein transport GO:0006886 270 0.018
regulation of cellular response to stress GO:0080135 244 0.018
gtp metabolic process GO:0046039 239 0.018
regulation of ras protein signal transduction GO:0046578 155 0.017
protein localization to organelle GO:0033365 280 0.017
regulation of protein transport GO:0051223 213 0.017
regulation of cytokine production GO:0001817 232 0.017
regeneration GO:0031099 4 0.017
regulation of protein localization GO:0032880 296 0.017
chromosome segregation GO:0007059 114 0.017
response to cytokine GO:0034097 232 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
regulation of immune response GO:0050776 201 0.017
organelle fission GO:0048285 149 0.017
regulation of gtpase activity GO:0043087 180 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
negative regulation of cell cycle process GO:0010948 121 0.017
cell projection organization GO:0030030 252 0.017
cellular response to lipid GO:0071396 127 0.016
response to ionizing radiation GO:0010212 65 0.016
gene silencing GO:0016458 49 0.016
neuromuscular junction development GO:0007528 3 0.016
maintenance of location GO:0051235 112 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
mitotic cell cycle GO:0000278 326 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
protein acetylation GO:0006473 116 0.016
response to organic cyclic compound GO:0014070 204 0.016
cell development GO:0048468 328 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
negative regulation of protein modification process GO:0031400 200 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
mapk cascade GO:0000165 288 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
cell cycle checkpoint GO:0000075 117 0.015
protein homooligomerization GO:0051260 100 0.015
regulation of protein kinase activity GO:0045859 289 0.015
biological adhesion GO:0022610 331 0.015
spermatid differentiation GO:0048515 4 0.015
cytokine production GO:0001816 247 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
cell adhesion GO:0007155 325 0.015
meiotic chromosome segregation GO:0045132 4 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
regulation of transferase activity GO:0051338 355 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
protein alkylation GO:0008213 74 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
cellular component morphogenesis GO:0032989 314 0.015
response to radiation GO:0009314 151 0.015
response to fungus GO:0009620 4 0.014
chromatin assembly or disassembly GO:0006333 78 0.014
anterior posterior axis specification GO:0009948 2 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
internal peptidyl lysine acetylation GO:0018393 97 0.014
regulation of response to external stimulus GO:0032101 222 0.014
response to nitrogen compound GO:1901698 184 0.014
regulation of proteolysis GO:0030162 293 0.014
peptidyl lysine acetylation GO:0018394 101 0.014
embryonic placenta development GO:0001892 1 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
single organism membrane organization GO:0044802 268 0.014
response to oxidative stress GO:0006979 121 0.014
single organism reproductive process GO:0044702 98 0.014
macromolecule methylation GO:0043414 97 0.014
response to molecule of bacterial origin GO:0002237 82 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
protein catabolic process GO:0030163 325 0.014
cellular homeostasis GO:0019725 196 0.014
ion homeostasis GO:0050801 230 0.014
memory GO:0007613 3 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
reproductive process GO:0022414 106 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
translation GO:0006412 132 0.014
cardiovascular system development GO:0072358 262 0.014
positive regulation of kinase activity GO:0033674 204 0.014
negative regulation of cytokine production GO:0001818 82 0.014
regulation of kinase activity GO:0043549 314 0.014
i kappab kinase nf kappab signaling GO:0007249 166 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
positive regulation of immune response GO:0050778 159 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
cellular protein catabolic process GO:0044257 261 0.013
lipid metabolic process GO:0006629 381 0.013
negative regulation of cell death GO:0060548 345 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
protein dephosphorylation GO:0006470 81 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
rhythmic behavior GO:0007622 2 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
positive regulation of cell death GO:0010942 263 0.013
dna repair GO:0006281 198 0.013
carbohydrate metabolic process GO:0005975 207 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
regulation of defense response GO:0031347 154 0.013
meiosis i GO:0007127 4 0.013
compound eye development GO:0048749 1 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
rab protein signal transduction GO:0032482 4 0.013
nitrogen compound transport GO:0071705 191 0.013
cdc42 protein signal transduction GO:0032488 4 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
reproductive structure development GO:0048608 55 0.012
cell division GO:0051301 168 0.012
actin mediated cell contraction GO:0070252 12 0.012
defense response to fungus GO:0050832 4 0.012
tripartite regional subdivision GO:0007351 2 0.012
positive regulation of protein transport GO:0051222 135 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.012
regulation of dna metabolic process GO:0051052 153 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
epithelium development GO:0060429 227 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
secretion by cell GO:0032940 226 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
digestive tract development GO:0048565 75 0.012
protein maturation GO:0051604 233 0.012
positive regulation of rab gtpase activity GO:0032851 39 0.012
internal protein amino acid acetylation GO:0006475 101 0.012
circadian behavior GO:0048512 2 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
secretion GO:0046903 254 0.012
nuclear division GO:0000280 128 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
tube development GO:0035295 125 0.012
response to wounding GO:0009611 168 0.012
spermatid development GO:0007286 4 0.012
positive regulation of cell development GO:0010720 92 0.012
mitochondrion organization GO:0007005 156 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
protein localization to membrane GO:0072657 160 0.012
neural tube formation GO:0001841 3 0.012
double strand break repair GO:0006302 101 0.011
cellular lipid metabolic process GO:0044255 303 0.011
response to inorganic substance GO:0010035 127 0.011
regulation of dephosphorylation GO:0035303 96 0.011
protein processing GO:0016485 226 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
anatomical structure homeostasis GO:0060249 100 0.011
regulation of cell projection organization GO:0031344 107 0.011
regulation of cell cycle process GO:0010564 266 0.011
metal ion transport GO:0030001 272 0.011
system process GO:0003008 349 0.011
protein targeting GO:0006605 187 0.011
circulatory system development GO:0072359 262 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
endosomal transport GO:0016197 129 0.011
histone h3 acetylation GO:0043966 45 0.011
neural tube closure GO:0001843 3 0.011
tissue regeneration GO:0042246 3 0.011
regulation of cell development GO:0060284 161 0.011
histone methylation GO:0016571 60 0.011
cellular response to biotic stimulus GO:0071216 71 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
glycoprotein metabolic process GO:0009100 110 0.011
oocyte development GO:0048599 1 0.011
peptidyl lysine modification GO:0018205 144 0.011
sensory perception of smell GO:0007608 2 0.011
growth GO:0040007 202 0.011
reproductive system development GO:0061458 56 0.011
chemical homeostasis GO:0048878 306 0.011
cell part morphogenesis GO:0032990 137 0.011
alcohol metabolic process GO:0006066 114 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
transmembrane transport GO:0055085 399 0.011
regulation of intracellular transport GO:0032386 195 0.011
regulation of multi organism process GO:0043900 157 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
oocyte differentiation GO:0009994 2 0.010
cellular protein complex assembly GO:0043623 188 0.010
hindbrain development GO:0030902 3 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
nucleosome assembly GO:0006334 50 0.010
regulation of mrna metabolic process GO:1903311 53 0.010
leukocyte activation GO:0045321 164 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
intracellular mrna localization GO:0008298 1 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.010
cytokine mediated signaling pathway GO:0019221 109 0.010
activation of protein kinase activity GO:0032147 90 0.010
dna damage checkpoint GO:0000077 68 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
regulation of binding GO:0051098 111 0.010
negative regulation of apoptotic process GO:0043066 316 0.010

SYMPK disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.061
disease of cellular proliferation DOID:14566 174 0.061
organ system cancer DOID:0050686 164 0.061
central nervous system disease DOID:331 186 0.034
nervous system disease DOID:863 431 0.034
gastrointestinal system cancer DOID:3119 52 0.024
musculoskeletal system disease DOID:17 223 0.020
disease of metabolism DOID:0014667 295 0.014
sensory system disease DOID:0050155 203 0.011