Homo sapiens

5 known processes

HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10

(Aliases: MRPP2,17b-HSD10,ERAB,MRX31,ABAD,DUPXp11.22,CAMR,MHBD,SDR5C1,SCHAD,HCD2,HADH2,MRX17,MRXS10)

HSD17B10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 156 0.832
post embryonic development GO:0009791 2 0.754
Worm Fly
monocarboxylic acid metabolic process GO:0032787 185 0.383
Fly
regulation of apoptotic signaling pathway GO:2001233 175 0.383
multicellular organismal aging GO:0010259 3 0.380
regulation of proteolysis GO:0030162 293 0.332
immune response GO:0006955 307 0.321
lipid metabolic process GO:0006629 381 0.317
Human Fly
cellular lipid metabolic process GO:0044255 303 0.281
Fly
oxidation reduction process GO:0055114 396 0.244
regulation of peptidase activity GO:0052547 180 0.215
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.197
ribonucleoside triphosphate metabolic process GO:0009199 412 0.167
protein processing GO:0016485 226 0.158
purine nucleoside triphosphate metabolic process GO:0009144 412 0.157
protein localization to organelle GO:0033365 280 0.154
response to oxygen containing compound GO:1901700 369 0.151
nucleoside triphosphate metabolic process GO:0009141 422 0.149
determination of adult lifespan GO:0008340 2 0.147
growth GO:0040007 202 0.135
endocytosis GO:0006897 159 0.133
adult locomotory behavior GO:0008344 1 0.127
positive regulation of apoptotic process GO:0043065 246 0.124
membrane organization GO:0061024 292 0.124
purine nucleoside monophosphate metabolic process GO:0009126 186 0.121
regulation of growth GO:0040008 165 0.119
positive regulation of cell death GO:0010942 263 0.116
purine ribonucleoside metabolic process GO:0046128 437 0.115
cell development GO:0048468 328 0.109
female gamete generation GO:0007292 2 0.109
negative regulation of multicellular organismal process GO:0051241 317 0.105
single organism membrane organization GO:0044802 268 0.104
mitochondrial transport GO:0006839 60 0.103
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.097
cofactor metabolic process GO:0051186 87 0.090
Fly
positive regulation of programmed cell death GO:0043068 249 0.089
apoptotic signaling pathway GO:0097190 268 0.089
protein maturation GO:0051604 233 0.088
positive regulation of proteolysis GO:0045862 142 0.086
atp metabolic process GO:0046034 176 0.082
locomotory behavior GO:0007626 1 0.081
positive regulation of hydrolase activity GO:0051345 331 0.078
reactive oxygen species metabolic process GO:0072593 75 0.077
carbohydrate derivative biosynthetic process GO:1901137 207 0.077
cellular response to oxygen containing compound GO:1901701 276 0.073
negative regulation of programmed cell death GO:0043069 321 0.072
negative regulation of immune system process GO:0002683 136 0.070
nucleotide catabolic process GO:0009166 408 0.069
regulation of immune response GO:0050776 201 0.069
negative regulation of protein maturation GO:1903318 142 0.069
regulation of purine nucleotide metabolic process GO:1900542 264 0.068
regulation of endopeptidase activity GO:0052548 170 0.067
oogenesis GO:0048477 2 0.065
intracellular protein transport GO:0006886 270 0.063
behavior GO:0007610 112 0.062
posttranscriptional regulation of gene expression GO:0010608 213 0.062
organic hydroxy compound biosynthetic process GO:1901617 71 0.060
mitochondrial membrane organization GO:0007006 40 0.060
negative regulation of cell death GO:0060548 345 0.059
positive regulation of cellular component organization GO:0051130 376 0.059
regulation of cysteine type endopeptidase activity GO:2000116 127 0.058
cellular metal ion homeostasis GO:0006875 146 0.057
protein catabolic process GO:0030163 325 0.055
organonitrogen compound biosynthetic process GO:1901566 200 0.054
regulation of membrane potential GO:0042391 95 0.054
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.051
cellular component morphogenesis GO:0032989 314 0.051
organophosphate catabolic process GO:0046434 430 0.051
fatty acid metabolic process GO:0006631 115 0.050
Fly
amine metabolic process GO:0009308 44 0.050
defense response GO:0006952 315 0.049
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.047
immune effector process GO:0002252 159 0.047
metal ion homeostasis GO:0055065 169 0.047
regulation of protein maturation GO:1903317 150 0.046
ribonucleotide catabolic process GO:0009261 405 0.046
regulation of nucleoside metabolic process GO:0009118 209 0.045
glycosyl compound catabolic process GO:1901658 413 0.044
ribonucleoside monophosphate metabolic process GO:0009161 187 0.044
embryo development GO:0009790 123 0.044
nucleoside triphosphate catabolic process GO:0009143 394 0.043
receptor mediated endocytosis GO:0006898 84 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
extrinsic apoptotic signaling pathway GO:0097191 119 0.043
cellular amino acid metabolic process GO:0006520 116 0.042
negative regulation of proteolysis GO:0045861 132 0.041
negative regulation of transport GO:0051051 176 0.041
organic hydroxy compound metabolic process GO:1901615 147 0.040
Fly
regulation of response to external stimulus GO:0032101 222 0.040
regulation of defense response GO:0031347 154 0.040
cellular homeostasis GO:0019725 196 0.040
biological adhesion GO:0022610 331 0.040
negative regulation of protein metabolic process GO:0051248 391 0.039
response to external biotic stimulus GO:0043207 261 0.039
positive regulation of developmental process GO:0051094 314 0.038
purine nucleotide catabolic process GO:0006195 405 0.038
negative regulation of apoptotic signaling pathway GO:2001234 97 0.037
cellular amine metabolic process GO:0044106 41 0.036
positive regulation of peptidase activity GO:0010952 88 0.036
negative regulation of protein processing GO:0010955 142 0.036
response to oxidative stress GO:0006979 121 0.035
positive regulation of catabolic process GO:0009896 310 0.035
purine nucleoside triphosphate catabolic process GO:0009146 392 0.035
vesicle mediated transport GO:0016192 371 0.035
small molecule catabolic process GO:0044282 92 0.034
establishment of protein localization to organelle GO:0072594 172 0.034
negative regulation of cellular component organization GO:0051129 235 0.033
intrinsic apoptotic signaling pathway GO:0097193 127 0.033
negative regulation of cell proliferation GO:0008285 228 0.033
regulation of protein localization GO:0032880 296 0.032
single organism cellular localization GO:1902580 332 0.032
positive regulation of transport GO:0051050 336 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.031
ion homeostasis GO:0050801 230 0.030
mitochondrial calcium ion homeostasis GO:0051560 11 0.030
aging GO:0007568 66 0.030
Rat
cellular macromolecule catabolic process GO:0044265 380 0.030
nucleotide biosynthetic process GO:0009165 109 0.030
response to lipid GO:0033993 206 0.030
negative regulation of phosphate metabolic process GO:0045936 267 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
guanosine containing compound catabolic process GO:1901069 239 0.028
protein localization to membrane GO:0072657 160 0.028
protein import into mitochondrial inner membrane GO:0045039 3 0.028
protein targeting GO:0006605 187 0.027
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.027
cytokine production GO:0001816 247 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
cytoplasmic transport GO:0016482 379 0.027
cellular response to lipid GO:0071396 127 0.027
cellular ion homeostasis GO:0006873 168 0.026
positive regulation of dna metabolic process GO:0051054 73 0.026
secretion GO:0046903 254 0.026
positive regulation of endopeptidase activity GO:0010950 84 0.026
nucleoside catabolic process GO:0009164 408 0.026
positive regulation of nucleotide metabolic process GO:0045981 230 0.026
negative regulation of phosphorylation GO:0042326 174 0.026
negative regulation of developmental process GO:0051093 247 0.025
protein localization to mitochondrion GO:0070585 25 0.025
reproductive system development GO:0061458 56 0.025
Rat Worm
cellular cation homeostasis GO:0030003 163 0.025
inner mitochondrial membrane organization GO:0007007 8 0.025
response to biotic stimulus GO:0009607 276 0.025
divalent inorganic cation homeostasis GO:0072507 136 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
negative regulation of immune response GO:0050777 40 0.024
protein oligomerization GO:0051259 173 0.024
Rat
negative regulation of growth GO:0045926 97 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
t cell activation GO:0042110 99 0.024
regulation of kinase activity GO:0043549 314 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.023
regulation of protein processing GO:0070613 150 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
chemical homeostasis GO:0048878 306 0.023
innate immune response GO:0045087 178 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
dna replication GO:0006260 116 0.022
negative regulation of transferase activity GO:0051348 124 0.022
regulation of transmembrane transporter activity GO:0022898 74 0.022
system process GO:0003008 349 0.021
secretion by cell GO:0032940 226 0.021
sex differentiation GO:0007548 45 0.021
Rat Worm
ribonucleoside catabolic process GO:0042454 406 0.021
response to cytokine GO:0034097 232 0.021
regulation of intracellular protein transport GO:0033157 123 0.021
regulation of intracellular transport GO:0032386 195 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
regulation of cell development GO:0060284 161 0.021
regulation of secretion GO:0051046 194 0.020
developmental process involved in reproduction GO:0003006 66 0.020
Rat Worm
nitrogen compound transport GO:0071705 191 0.020
regulation of cell differentiation GO:0045595 393 0.020
positive regulation of organelle organization GO:0010638 195 0.020
cellular calcium ion homeostasis GO:0006874 117 0.020
regulation of transferase activity GO:0051338 355 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
reproduction GO:0000003 63 0.019
Worm
cation homeostasis GO:0055080 189 0.019
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
regulation of mitochondrial membrane potential GO:0051881 23 0.018
response to other organism GO:0051707 261 0.018
cardiovascular system development GO:0072358 262 0.018
single organism reproductive process GO:0044702 98 0.018
Rat Worm
protein import GO:0017038 130 0.018
regulation of cellular ketone metabolic process GO:0010565 50 0.018
phospholipid metabolic process GO:0006644 99 0.018
mrna metabolic process GO:0016071 175 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.017
transmembrane transport GO:0055085 399 0.017
response to abiotic stimulus GO:0009628 336 0.017
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
cell activation GO:0001775 213 0.017
regulation of protein targeting GO:1903533 91 0.017
nervous system development GO:0007399 293 0.017
cell adhesion GO:0007155 325 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
negative regulation of hydrolase activity GO:0051346 182 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
purine containing compound catabolic process GO:0072523 411 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
positive regulation of apoptotic signaling pathway GO:2001235 70 0.016
ribonucleotide biosynthetic process GO:0009260 81 0.016
cellular protein catabolic process GO:0044257 261 0.015
calcium ion homeostasis GO:0055074 122 0.015
neuromuscular junction development GO:0007528 3 0.015
regulation of secretion by cell GO:1903530 177 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
leukocyte activation GO:0045321 164 0.015
response to bacterium GO:0009617 144 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
cell part morphogenesis GO:0032990 137 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
response to acid chemical GO:0001101 66 0.015
covalent chromatin modification GO:0016569 254 0.015
response to hormone GO:0009725 175 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
epithelial cell proliferation GO:0050673 128 0.014
activation of immune response GO:0002253 114 0.014
gtp catabolic process GO:0006184 237 0.014
regulation of protein catabolic process GO:0042176 155 0.014
regulation of mitochondrion organization GO:0010821 54 0.014
rna interference GO:0016246 4 0.014
gtp metabolic process GO:0046039 239 0.014
purine ribonucleotide biosynthetic process GO:0009152 79 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
alcohol metabolic process GO:0006066 114 0.013
Fly
embryo development ending in birth or egg hatching GO:0009792 34 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
regulation of multicellular organism growth GO:0040014 8 0.013
cellular response to acid chemical GO:0071229 44 0.013
ribose phosphate biosynthetic process GO:0046390 82 0.013
microtubule based process GO:0007017 210 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
gene silencing GO:0016458 49 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
negative regulation of catabolic process GO:0009895 104 0.013
protein acetylation GO:0006473 116 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
regulation of cell growth GO:0001558 135 0.013
actin filament based process GO:0030029 224 0.013
osteoblast differentiation GO:0001649 92 0.012
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.012
gonad development GO:0008406 34 0.012
Rat Worm
regulation of gtpase activity GO:0043087 180 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
regulation of gene expression epigenetic GO:0040029 73 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
cell type specific apoptotic process GO:0097285 125 0.012
organic acid biosynthetic process GO:0016053 97 0.012
regulation of binding GO:0051098 111 0.012
positive regulation of protein transport GO:0051222 135 0.011
developmental growth GO:0048589 48 0.011
cell growth GO:0016049 160 0.011
chromatin organization GO:0006325 351 0.011
negative regulation of kinase activity GO:0033673 106 0.011
lymphocyte activation GO:0046649 133 0.011
negative regulation of defense response GO:0031348 47 0.011
regulation of inflammatory response GO:0050727 46 0.011
glycerophospholipid metabolic process GO:0006650 84 0.011
positive regulation of immune system process GO:0002684 283 0.011
hemopoiesis GO:0030097 180 0.011
mitochondrion morphogenesis GO:0070584 8 0.011
small molecule biosynthetic process GO:0044283 157 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
negative regulation of intracellular transport GO:0032387 60 0.011
positive regulation of lipid metabolic process GO:0045834 50 0.011
dna repair GO:0006281 198 0.011
protein acylation GO:0043543 138 0.010
single organism cell adhesion GO:0098602 179 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
chromatin modification GO:0016568 298 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.010

HSD17B10 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.129
porphyria DOID:13268 8 0.129
inherited metabolic disorder DOID:655 242 0.129
central nervous system disease DOID:331 186 0.023
nervous system disease DOID:863 431 0.023
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.019
neurodegenerative disease DOID:1289 102 0.012