Homo sapiens

24 known processes

RAP1GDS1

RAP1, GTP-GDP dissociation stimulator 1

(Aliases: MGC118859,SmgGDS,GDS1,MGC118861)

RAP1GDS1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.565
ribonucleoside triphosphate catabolic process GO:0009203 391 0.225
purine ribonucleoside metabolic process GO:0046128 437 0.212
organophosphate catabolic process GO:0046434 430 0.206
positive regulation of nucleotide catabolic process GO:0030813 185 0.205
purine nucleoside catabolic process GO:0006152 398 0.200
purine nucleoside triphosphate catabolic process GO:0009146 392 0.177
rho protein signal transduction GO:0007266 26 0.174
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.174
positive regulation of catabolic process GO:0009896 310 0.165
gtp metabolic process GO:0046039 239 0.162
ribonucleotide catabolic process GO:0009261 405 0.149
guanosine containing compound catabolic process GO:1901069 239 0.148
purine ribonucleoside catabolic process GO:0046130 398 0.146
nucleoside catabolic process GO:0009164 408 0.141
glycosyl compound catabolic process GO:1901658 413 0.132
small gtpase mediated signal transduction GO:0007264 78 0.129
gtp catabolic process GO:0006184 237 0.127
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.124
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.124
nucleoside triphosphate catabolic process GO:0009143 394 0.122
regulation of nucleotide catabolic process GO:0030811 205 0.118
nucleoside triphosphate metabolic process GO:0009141 422 0.115
nucleotide catabolic process GO:0009166 408 0.115
guanosine containing compound metabolic process GO:1901068 244 0.114
ribonucleoside triphosphate metabolic process GO:0009199 412 0.113
regulation of gtp catabolic process GO:0033124 180 0.111
regulation of nucleoside metabolic process GO:0009118 209 0.108
ribonucleoside catabolic process GO:0042454 406 0.108
positive regulation of cellular catabolic process GO:0031331 284 0.106
positive regulation of nucleotide metabolic process GO:0045981 230 0.099
actin filament based process GO:0030029 224 0.099
ras protein signal transduction GO:0007265 73 0.098
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.094
negative regulation of cell death GO:0060548 345 0.093
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.090
negative regulation of apoptotic process GO:0043066 316 0.090
positive regulation of hydrolase activity GO:0051345 331 0.088
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.087
organonitrogen compound biosynthetic process GO:1901566 200 0.086
single organism cellular localization GO:1902580 332 0.086
regulation of purine nucleotide metabolic process GO:1900542 264 0.086
purine containing compound catabolic process GO:0072523 411 0.086
positive regulation of nucleoside metabolic process GO:0045979 186 0.085
regulation of small gtpase mediated signal transduction GO:0051056 156 0.083
neuromuscular junction development GO:0007528 3 0.083
positive regulation of ras gtpase activity GO:0032320 117 0.080
negative regulation of catalytic activity GO:0043086 335 0.080
rab protein signal transduction GO:0032482 4 0.079
regulation of nucleotide metabolic process GO:0006140 269 0.079
vesicle mediated transport GO:0016192 371 0.078
determination of adult lifespan GO:0008340 2 0.075
nucleoside phosphate catabolic process GO:1901292 412 0.073
negative regulation of programmed cell death GO:0043069 321 0.073
microtubule cytoskeleton organization GO:0000226 176 0.071
negative regulation of phosphate metabolic process GO:0045936 267 0.071
purine nucleotide catabolic process GO:0006195 405 0.069
positive regulation of gtp catabolic process GO:0033126 166 0.067
dephosphorylation GO:0016311 209 0.067
nucleoside phosphate biosynthetic process GO:1901293 109 0.066
anterior posterior axis specification GO:0009948 2 0.066
positive regulation of gtpase activity GO:0043547 166 0.066
microtubule based process GO:0007017 210 0.066
regulation of gtpase activity GO:0043087 180 0.065
oogenesis GO:0048477 2 0.064
cell adhesion GO:0007155 325 0.061
positive regulation of cellular component organization GO:0051130 376 0.061
cell projection organization GO:0030030 252 0.058
regulation of protein serine threonine kinase activity GO:0071900 179 0.057
cellular amino acid metabolic process GO:0006520 116 0.057
regulation of protein localization GO:0032880 296 0.057
regulation of purine nucleotide catabolic process GO:0033121 205 0.057
negative regulation of protein metabolic process GO:0051248 391 0.055
response to nitrogen compound GO:1901698 184 0.055
single organismal cell cell adhesion GO:0016337 148 0.054
regulation of ras gtpase activity GO:0032318 128 0.054
negative regulation of phosphorus metabolic process GO:0010563 267 0.053
regulation of cellular component biogenesis GO:0044087 281 0.052
positive regulation of rho gtpase activity GO:0032321 56 0.052
cellular component morphogenesis GO:0032989 314 0.052
regulation of cell adhesion GO:0030155 166 0.051
purine ribonucleotide catabolic process GO:0009154 404 0.051
response to oxygen containing compound GO:1901700 369 0.050
locomotory behavior GO:0007626 1 0.050
morphogenesis of embryonic epithelium GO:0016331 4 0.049
secretion GO:0046903 254 0.049
cellular ketone metabolic process GO:0042180 80 0.049
actin cytoskeleton organization GO:0030036 207 0.047
cell development GO:0048468 328 0.047
multicellular organismal aging GO:0010259 3 0.047
transmembrane transport GO:0055085 399 0.046
protein polymerization GO:0051258 71 0.045
female gamete generation GO:0007292 2 0.045
cellular amine metabolic process GO:0044106 41 0.045
regulation of ras protein signal transduction GO:0046578 155 0.044
regulation of transferase activity GO:0051338 355 0.044
regulation of rho protein signal transduction GO:0035023 79 0.044
positive regulation of protein phosphorylation GO:0001934 313 0.043
purine nucleotide biosynthetic process GO:0006164 84 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.042
regulation of cytoskeleton organization GO:0051493 177 0.042
tripartite regional subdivision GO:0007351 2 0.042
wound healing GO:0042060 115 0.041
mitotic cell cycle process GO:1903047 286 0.041
anterior posterior axis specification embryo GO:0008595 2 0.041
ribonucleotide biosynthetic process GO:0009260 81 0.041
regulation of actin filament based process GO:0032970 141 0.040
oocyte differentiation GO:0009994 2 0.040
regulation of rho gtpase activity GO:0032319 66 0.039
g protein coupled receptor signaling pathway GO:0007186 207 0.038
regulation of apoptotic signaling pathway GO:2001233 175 0.038
regulation of protein kinase activity GO:0045859 289 0.038
positive regulation of organelle organization GO:0010638 195 0.038
positive regulation of developmental process GO:0051094 314 0.037
positive regulation of cellular component biogenesis GO:0044089 158 0.037
protein processing GO:0016485 226 0.037
regulation of kinase activity GO:0043549 314 0.036
single organism cell adhesion GO:0098602 179 0.036
endocytosis GO:0006897 159 0.036
amine metabolic process GO:0009308 44 0.036
system process GO:0003008 349 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
mitotic cell cycle GO:0000278 326 0.035
protein maturation GO:0051604 233 0.035
peripheral nervous system development GO:0007422 2 0.034
positive regulation of protein complex assembly GO:0031334 86 0.034
cytoplasmic transport GO:0016482 379 0.034
response to wounding GO:0009611 168 0.033
cation transmembrane transport GO:0098655 238 0.033
regulation of protein catabolic process GO:0042176 155 0.033
nucleotide biosynthetic process GO:0009165 109 0.033
nuclear division GO:0000280 128 0.033
carbohydrate derivative biosynthetic process GO:1901137 207 0.033
protein localization to organelle GO:0033365 280 0.033
protein catabolic process GO:0030163 325 0.032
biological adhesion GO:0022610 331 0.032
regulation of growth GO:0040008 165 0.032
nervous system development GO:0007399 293 0.032
secretion by cell GO:0032940 226 0.031
organophosphate biosynthetic process GO:0090407 163 0.031
defense response GO:0006952 315 0.031
positive regulation of kinase activity GO:0033674 204 0.031
cellular protein complex assembly GO:0043623 188 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
intracellular protein transport GO:0006886 270 0.031
cellular macromolecule catabolic process GO:0044265 380 0.030
nucleoside monophosphate metabolic process GO:0009123 191 0.030
response to organonitrogen compound GO:0010243 156 0.030
negative regulation of protein modification process GO:0031400 200 0.030
oocyte development GO:0048599 1 0.029
negative regulation of phosphorylation GO:0042326 174 0.029
positive regulation of rac gtpase activity GO:0032855 31 0.029
positive regulation of protein kinase activity GO:0045860 190 0.029
response to abiotic stimulus GO:0009628 336 0.029
single organism membrane organization GO:0044802 268 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.029
regulation of establishment of protein localization GO:0070201 242 0.028
positive regulation of rab gtpase activity GO:0032851 39 0.028
negative regulation of cellular component organization GO:0051129 235 0.028
positive regulation of phosphorylation GO:0042327 394 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
positive regulation of transport GO:0051050 336 0.027
regulation of cell cell adhesion GO:0022407 57 0.027
memory GO:0007613 3 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.027
ubiquitin dependent protein catabolic process GO:0006511 206 0.027
regulation of secretion GO:0051046 194 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.027
regulation of protein transport GO:0051223 213 0.026
inorganic ion transmembrane transport GO:0098660 231 0.026
membrane organization GO:0061024 292 0.026
organelle assembly GO:0070925 176 0.026
regulation of secretion by cell GO:1903530 177 0.026
regulation of cell projection organization GO:0031344 107 0.026
response to other organism GO:0051707 261 0.026
apoptotic signaling pathway GO:0097190 268 0.025
small molecule biosynthetic process GO:0044283 157 0.025
receptor mediated endocytosis GO:0006898 84 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
regulation of protein polymerization GO:0032271 63 0.024
cell division GO:0051301 168 0.024
positive regulation of transferase activity GO:0051347 227 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
organelle inheritance GO:0048308 2 0.024
endomembrane system organization GO:0010256 196 0.024
divalent inorganic cation transport GO:0072511 158 0.024
negative regulation of protein phosphorylation GO:0001933 140 0.024
stem cell division GO:0017145 2 0.024
cellular response to oxygen containing compound GO:1901701 276 0.023
regulation of protein maturation GO:1903317 150 0.023
ion homeostasis GO:0050801 230 0.023
regulation of cell cycle GO:0051726 393 0.023
regulation of proteolysis GO:0030162 293 0.023
actin filament organization GO:0007015 128 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
embryo development GO:0009790 123 0.023
segmentation GO:0035282 4 0.023
protein ubiquitination GO:0016567 314 0.023
regulation of cellular response to stress GO:0080135 244 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.022
maintenance of location GO:0051235 112 0.022
associative learning GO:0008306 1 0.022
regulation of actin cytoskeleton organization GO:0032956 116 0.022
immune response GO:0006955 307 0.022
regulation of protein targeting GO:1903533 91 0.022
regulation of protein processing GO:0070613 150 0.022
ion transmembrane transport GO:0034220 338 0.022
purine containing compound biosynthetic process GO:0072522 88 0.022
innate immune response GO:0045087 178 0.022
carboxylic acid biosynthetic process GO:0046394 97 0.022
cellular protein catabolic process GO:0044257 261 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
metal ion transport GO:0030001 272 0.022
protein localization to membrane GO:0072657 160 0.021
lipid metabolic process GO:0006629 381 0.021
engulfment of apoptotic cell GO:0043652 2 0.021
cytokinesis GO:0000910 96 0.021
inorganic cation transmembrane transport GO:0098662 194 0.021
regulation of intracellular transport GO:0032386 195 0.021
negative regulation of protein processing GO:0010955 142 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
intracellular mrna localization GO:0008298 1 0.021
neurological system process GO:0050877 163 0.021
regulation of mitotic cell cycle GO:0007346 189 0.020
generation of neurons GO:0048699 152 0.020
cerebral cortex cell migration GO:0021795 3 0.020
cell growth GO:0016049 160 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
regulation of actin polymerization or depolymerization GO:0008064 56 0.020
positive regulation of secretion by cell GO:1903532 108 0.020
peptidyl serine modification GO:0018209 106 0.020
modification dependent protein catabolic process GO:0019941 209 0.019
actin filament based movement GO:0030048 17 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
regulation of locomotion GO:0040012 329 0.019
regulation of response to external stimulus GO:0032101 222 0.019
cation transport GO:0006812 331 0.019
growth GO:0040007 202 0.019
cellular lipid metabolic process GO:0044255 303 0.019
regulation of neuron death GO:1901214 56 0.019
meiotic chromosome segregation GO:0045132 4 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
positive regulation of protein transport GO:0051222 135 0.019
negative regulation of transferase activity GO:0051348 124 0.019
cell cell signaling GO:0007267 155 0.019
protein targeting GO:0006605 187 0.018
regulation of rab protein signal transduction GO:0032483 39 0.018
response to organic cyclic compound GO:0014070 204 0.018
chromosome segregation GO:0007059 114 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
cell projection morphogenesis GO:0048858 129 0.018
regulation of cellular protein catabolic process GO:1903362 96 0.018
cell morphogenesis GO:0000902 296 0.017
positive regulation of protein polymerization GO:0032273 45 0.017
sulfur compound metabolic process GO:0006790 101 0.017
divalent metal ion transport GO:0070838 152 0.017
nuclear transport GO:0051169 179 0.017
neuron development GO:0048666 113 0.017
neuroblast proliferation GO:0007405 4 0.017
negative regulation of protein maturation GO:1903318 142 0.017
mapk cascade GO:0000165 288 0.017
positive regulation of cytoskeleton organization GO:0051495 83 0.017
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
circulatory system development GO:0072359 262 0.017
regulation of protein complex assembly GO:0043254 147 0.017
endosomal transport GO:0016197 129 0.017
organelle fission GO:0048285 149 0.017
regulation of mapk cascade GO:0043408 262 0.017
positive regulation of intracellular protein transport GO:0090316 76 0.017
blastoderm segmentation GO:0007350 2 0.016
asymmetric neuroblast division GO:0055059 1 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
rna interference GO:0016246 4 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
regulation of anatomical structure size GO:0090066 101 0.016
regulation of cell development GO:0060284 161 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
regulation of rab gtpase activity GO:0032313 39 0.016
mitochondrion distribution GO:0048311 3 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
regulation of cell cycle process GO:0010564 266 0.015
protein localization to nucleus GO:0034504 136 0.015
autophagy GO:0006914 88 0.015
regulation of membrane potential GO:0042391 95 0.015
neuron death GO:0070997 65 0.015
chemotaxis GO:0006935 157 0.015
calcium ion transport GO:0006816 147 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
protein targeting to nucleus GO:0044744 104 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
meiosis i GO:0007127 4 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
epithelium development GO:0060429 227 0.015
neuron projection development GO:0031175 106 0.015
negative regulation of cell cycle GO:0045786 193 0.015
negative regulation of transport GO:0051051 176 0.015
positive regulation of cell adhesion GO:0045785 84 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
establishment or maintenance of cell polarity GO:0007163 31 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
neuron differentiation GO:0030182 138 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
morphogenesis of an epithelium GO:0002009 60 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
negative regulation of developmental process GO:0051093 247 0.014
sleep GO:0030431 2 0.014
negative regulation of protein kinase activity GO:0006469 98 0.014
vasculature development GO:0001944 181 0.014
chemical homeostasis GO:0048878 306 0.014
positive regulation of apoptotic signaling pathway GO:2001235 70 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
cell projection assembly GO:0030031 126 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.014
cell part morphogenesis GO:0032990 137 0.014
alpha amino acid metabolic process GO:1901605 72 0.014
organelle localization GO:0051640 84 0.013
blood vessel development GO:0001568 172 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
cellular homeostasis GO:0019725 196 0.013
anion transport GO:0006820 161 0.013
nitrogen compound transport GO:0071705 191 0.013
multicellular organismal response to stress GO:0033555 1 0.013
establishment of organelle localization GO:0051656 59 0.013
tissue morphogenesis GO:0048729 96 0.013
regulation of peptidase activity GO:0052547 180 0.013
neuron apoptotic process GO:0051402 39 0.013
regulation of nervous system development GO:0051960 88 0.013
positive regulation of cell projection organization GO:0031346 64 0.013
neurogenesis GO:0022008 169 0.013
cardiovascular system development GO:0072358 262 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of endocytosis GO:0030100 72 0.013
blood coagulation GO:0007596 76 0.013
synaptic transmission GO:0007268 61 0.013
tube development GO:0035295 125 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
regulation of dna metabolic process GO:0051052 153 0.013
metal ion homeostasis GO:0055065 169 0.013
potassium ion transport GO:0006813 62 0.013
protein import into nucleus GO:0006606 104 0.013
regulation of actin filament polymerization GO:0030833 50 0.013
lipid localization GO:0010876 106 0.013
single organism reproductive process GO:0044702 98 0.013
cellular metal ion homeostasis GO:0006875 146 0.012
regulation of ion transport GO:0043269 189 0.012
regeneration GO:0031099 4 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
adult locomotory behavior GO:0008344 1 0.012
purine ribonucleotide biosynthetic process GO:0009152 79 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
cell type specific apoptotic process GO:0097285 125 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
cdc42 protein signal transduction GO:0032488 4 0.012
nuclear import GO:0051170 106 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
immune system development GO:0002520 195 0.012
negative regulation of apoptotic signaling pathway GO:2001234 97 0.012
regulation of neurogenesis GO:0050767 82 0.012
organic acid biosynthetic process GO:0016053 97 0.012
negative regulation of protein transport GO:0051224 75 0.012
protein autophosphorylation GO:0046777 123 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
regulation of body fluid levels GO:0050878 99 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
circulatory system process GO:0003013 113 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
central nervous system development GO:0007417 123 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
developmental process involved in reproduction GO:0003006 66 0.012
response to ionizing radiation GO:0010212 65 0.012
actin polymerization or depolymerization GO:0008154 56 0.012
response to biotic stimulus GO:0009607 276 0.012
regulation of map kinase activity GO:0043405 108 0.011
spermatid development GO:0007286 4 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.011
response to external biotic stimulus GO:0043207 261 0.011
single organism nuclear import GO:1902593 104 0.011
hemopoiesis GO:0030097 180 0.011
dna replication GO:0006260 116 0.011
nerve development GO:0021675 4 0.011
actin mediated cell contraction GO:0070252 12 0.011
hyperosmotic response GO:0006972 4 0.011
regulation of neuron apoptotic process GO:0043523 35 0.011
response to hormone GO:0009725 175 0.011
regulation of neuron differentiation GO:0045664 70 0.011
hindbrain development GO:0030902 3 0.011
blood vessel morphogenesis GO:0048514 162 0.011
mitotic nuclear division GO:0007067 119 0.011
semaphorin plexin signaling pathway GO:0071526 4 0.011
histone modification GO:0016570 251 0.011
dendritic spine morphogenesis GO:0060997 3 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
response to metal ion GO:0010038 84 0.011
cell cycle checkpoint GO:0000075 117 0.011
embryonic morphogenesis GO:0048598 85 0.011
cellular cation homeostasis GO:0030003 163 0.011
regulation of metal ion transport GO:0010959 120 0.011
regulation of wound healing GO:0061041 56 0.011
response to growth factor GO:0070848 205 0.011
response to inorganic substance GO:0010035 127 0.011
head development GO:0060322 108 0.011
regulation of cell motility GO:2000145 299 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
oxidation reduction process GO:0055114 396 0.010
phospholipid metabolic process GO:0006644 99 0.010
response to bacterium GO:0009617 144 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
negative regulation of dephosphorylation GO:0035305 63 0.010
rna processing GO:0006396 255 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010

RAP1GDS1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.059
nervous system disease DOID:863 431 0.059
musculoskeletal system disease DOID:17 223 0.021
neurodegenerative disease DOID:1289 102 0.016
disease of metabolism DOID:0014667 295 0.015
inherited metabolic disorder DOID:655 242 0.015
epilepsy syndrome DOID:1826 41 0.015
brain disease DOID:936 73 0.015