Homo sapiens

78 known processes

PRDM9

PR domain containing 9

(Aliases: MSBP3,ZNF899,PRMD9,MEISETZ,PFM6)

PRDM9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 80 0.147
cellular amino acid metabolic process GO:0006520 116 0.092
amine metabolic process GO:0009308 44 0.091
regulation of cellular amine metabolic process GO:0033238 11 0.082
cellular amine metabolic process GO:0044106 41 0.082
ion transmembrane transport GO:0034220 338 0.080
regulation of cellular amino acid metabolic process GO:0006521 6 0.075
system process GO:0003008 349 0.070
transmembrane transport GO:0055085 399 0.063
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
regulation of cellular ketone metabolic process GO:0010565 50 0.059
post embryonic development GO:0009791 2 0.058
cardiac muscle cell contraction GO:0086003 4 0.054
positive regulation of cellular amine metabolic process GO:0033240 7 0.053
ras protein signal transduction GO:0007265 73 0.053
positive regulation of phosphorylation GO:0042327 394 0.051
signal transduction by phosphorylation GO:0023014 297 0.047
regulation of mapk cascade GO:0043408 262 0.040
negative regulation of protein metabolic process GO:0051248 391 0.037
small gtpase mediated signal transduction GO:0007264 78 0.036
muscle contraction GO:0006936 73 0.036
negative regulation of catalytic activity GO:0043086 335 0.034
rho protein signal transduction GO:0007266 26 0.034
chemical homeostasis GO:0048878 306 0.034
cation transport GO:0006812 331 0.034
neurological system process GO:0050877 163 0.033
mapk cascade GO:0000165 288 0.032
immune response GO:0006955 307 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.031
actin filament based process GO:0030029 224 0.031
positive regulation of protein phosphorylation GO:0001934 313 0.031
secretion GO:0046903 254 0.031
response to organic cyclic compound GO:0014070 204 0.031
muscle system process GO:0003012 81 0.031
regulation of cytokine production GO:0001817 232 0.031
purine containing compound catabolic process GO:0072523 411 0.031
positive regulation of cellular catabolic process GO:0031331 284 0.030
regulation of protein transport GO:0051223 213 0.030
positive regulation of transport GO:0051050 336 0.030
multicellular organismal aging GO:0010259 3 0.029
positive regulation of catabolic process GO:0009896 310 0.029
determination of adult lifespan GO:0008340 2 0.029
metal ion transport GO:0030001 272 0.028
positive regulation of cell proliferation GO:0008284 301 0.028
peptidyl tyrosine modification GO:0018212 170 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
locomotory behavior GO:0007626 1 0.028
regulation of transferase activity GO:0051338 355 0.028
cation transmembrane transport GO:0098655 238 0.028
regulation of secretion GO:0051046 194 0.028
insemination GO:0007320 1 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
organophosphate catabolic process GO:0046434 430 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.026
lipid metabolic process GO:0006629 381 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
cell development GO:0048468 328 0.026
nucleoside catabolic process GO:0009164 408 0.026
regulation of secretion by cell GO:1903530 177 0.026
peptidyl tyrosine phosphorylation GO:0018108 170 0.026
nucleotide catabolic process GO:0009166 408 0.026
regulation of kinase activity GO:0043549 314 0.026
cellular lipid metabolic process GO:0044255 303 0.025
mating GO:0007618 1 0.025
cytokine production GO:0001816 247 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
regulation of protein kinase activity GO:0045859 289 0.025
secretion by cell GO:0032940 226 0.025
female gamete generation GO:0007292 2 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
regeneration GO:0031099 4 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.023
cytoplasmic transport GO:0016482 379 0.023
inorganic ion transmembrane transport GO:0098660 231 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
regulation of establishment of protein localization GO:0070201 242 0.023
intracellular protein transport GO:0006886 270 0.023
positive regulation of hydrolase activity GO:0051345 331 0.023
response to nitrogen compound GO:1901698 184 0.023
actin mediated cell contraction GO:0070252 12 0.023
regulation of cellular component movement GO:0051270 334 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
regulation of transmembrane transport GO:0034762 139 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
neuromuscular junction development GO:0007528 3 0.022
metal ion homeostasis GO:0055065 169 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
cell morphogenesis GO:0000902 296 0.021
actin filament based movement GO:0030048 17 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
regulation of protein localization GO:0032880 296 0.021
regulation of multi organism process GO:0043900 157 0.021
regulation of ion transport GO:0043269 189 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
response to abiotic stimulus GO:0009628 336 0.021
positive regulation of mapk cascade GO:0043410 190 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
regulation of cellular response to stress GO:0080135 244 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
negative regulation of cell death GO:0060548 345 0.020
cellular chemical homeostasis GO:0055082 180 0.020
regulation of cell differentiation GO:0045595 393 0.020
nervous system development GO:0007399 293 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
protein processing GO:0016485 226 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
negative regulation of protein modification process GO:0031400 200 0.020
negative regulation of transport GO:0051051 176 0.020
vesicle mediated transport GO:0016192 371 0.020
cation homeostasis GO:0055080 189 0.020
g protein coupled receptor signaling pathway GO:0007186 207 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
oxidation reduction process GO:0055114 396 0.020
negative regulation of programmed cell death GO:0043069 321 0.019
apoptotic signaling pathway GO:0097190 268 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
oogenesis GO:0048477 2 0.019
monocarboxylic acid metabolic process GO:0032787 185 0.019
regulation of ion transmembrane transport GO:0034765 132 0.019
ion homeostasis GO:0050801 230 0.019
regulation of proteolysis GO:0030162 293 0.019
cellular homeostasis GO:0019725 196 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
positive regulation of organelle organization GO:0010638 195 0.019
positive regulation of acrosome reaction GO:2000344 4 0.019
response to oxygen containing compound GO:1901700 369 0.019
protein catabolic process GO:0030163 325 0.019
regulation of response to external stimulus GO:0032101 222 0.019
carbohydrate metabolic process GO:0005975 207 0.019
cellular component morphogenesis GO:0032989 314 0.019
protein maturation GO:0051604 233 0.019
regulation of map kinase activity GO:0043405 108 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
regulation of system process GO:0044057 101 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
regulation of intracellular transport GO:0032386 195 0.018
memory GO:0007613 3 0.018
associative learning GO:0008306 1 0.018
multi organism cellular process GO:0044764 156 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
response to cytokine GO:0034097 232 0.018
erk1 and erk2 cascade GO:0070371 104 0.018
small molecule biosynthetic process GO:0044283 157 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
protein localization to organelle GO:0033365 280 0.018
positive regulation of protein kinase activity GO:0045860 190 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
cell adhesion GO:0007155 325 0.017
regulation of acrosome reaction GO:0060046 4 0.017
fatty acid metabolic process GO:0006631 115 0.017
regulation of erk1 and erk2 cascade GO:0070372 99 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
regulation of membrane potential GO:0042391 95 0.017
regulation of immune response GO:0050776 201 0.017
membrane organization GO:0061024 292 0.017
anion transport GO:0006820 161 0.017
positive regulation of transferase activity GO:0051347 227 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
single organism membrane organization GO:0044802 268 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
lipid biosynthetic process GO:0008610 177 0.017
defense response GO:0006952 315 0.016
spermatid differentiation GO:0048515 4 0.016
divalent inorganic cation transport GO:0072511 158 0.016
dephosphorylation GO:0016311 209 0.016
regulation of cell migration GO:0030334 289 0.016
striated muscle contraction GO:0006941 52 0.016
purine nucleotide catabolic process GO:0006195 405 0.016
positive regulation of kinase activity GO:0033674 204 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
histone modification GO:0016570 251 0.016
spermatid development GO:0007286 4 0.016
chromatin modification GO:0016568 298 0.016
response to inorganic substance GO:0010035 127 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
blood circulation GO:0008015 113 0.016
interspecies interaction between organisms GO:0044419 156 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.016
biological adhesion GO:0022610 331 0.016
mitotic cell cycle GO:0000278 326 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
rhythmic behavior GO:0007622 2 0.015
negative regulation of developmental process GO:0051093 247 0.015
cellular ion homeostasis GO:0006873 168 0.015
regulation of actin filament based process GO:0032970 141 0.015
blastoderm segmentation GO:0007350 2 0.015
regulation of cell cycle GO:0051726 393 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
regulation of locomotion GO:0040012 329 0.015
positive regulation of locomotion GO:0040017 186 0.015
negative regulation of t cell cytokine production GO:0002725 4 0.015
nuclear transport GO:0051169 179 0.015
protein ubiquitination GO:0016567 314 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
positive regulation of developmental process GO:0051094 314 0.015
protein targeting GO:0006605 187 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
maintenance of location GO:0051235 112 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
copulation GO:0007620 1 0.015
cell growth GO:0016049 160 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
innate immune response GO:0045087 178 0.015
multicellular organismal signaling GO:0035637 34 0.014
gtp metabolic process GO:0046039 239 0.014
cardiac muscle contraction GO:0060048 34 0.014
cell projection organization GO:0030030 252 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
covalent chromatin modification GO:0016569 254 0.014
action potential GO:0001508 34 0.014
nitrogen compound transport GO:0071705 191 0.014
cellular cation homeostasis GO:0030003 163 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.014
positive regulation of immune system process GO:0002684 283 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
segmentation GO:0035282 4 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
regulation of leukocyte activation GO:0002694 115 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
adult locomotory behavior GO:0008344 1 0.014
monovalent inorganic cation transport GO:0015672 128 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
single organism cellular localization GO:1902580 332 0.014
response to other organism GO:0051707 261 0.014
divalent metal ion transport GO:0070838 152 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
glycoprotein metabolic process GO:0009100 110 0.014
regulation of protein catabolic process GO:0042176 155 0.014
circadian behavior GO:0048512 2 0.014
mitotic cell cycle process GO:1903047 286 0.014
regulation of gtpase activity GO:0043087 180 0.014
response to fungus GO:0009620 4 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
positive regulation of cell death GO:0010942 263 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
response to biotic stimulus GO:0009607 276 0.013
regulation of lymphocyte activation GO:0051249 103 0.013
positive regulation of cytokine production GO:0001819 167 0.013
hemopoiesis GO:0030097 180 0.013
protein oligomerization GO:0051259 173 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
viral process GO:0016032 146 0.013
detection of stimulus GO:0051606 85 0.013
oocyte development GO:0048599 1 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
circulatory system process GO:0003013 113 0.013
gtp catabolic process GO:0006184 237 0.013
positive regulation of cell development GO:0010720 92 0.013
tissue regeneration GO:0042246 3 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
lymphocyte activation GO:0046649 133 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
calcium ion transport GO:0006816 147 0.013
positive regulation of secretion GO:0051047 116 0.013
regulation of homeostatic process GO:0032844 121 0.013
regulation of cell cycle process GO:0010564 266 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
chromatin organization GO:0006325 351 0.013
response to virus GO:0009615 126 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
organic acid biosynthetic process GO:0016053 97 0.013
cellular protein catabolic process GO:0044257 261 0.013
cardiovascular system development GO:0072358 262 0.013
cellular protein complex assembly GO:0043623 188 0.012
negative regulation of transferase activity GO:0051348 124 0.012
positive regulation of protein transport GO:0051222 135 0.012
positive regulation of cell migration GO:0030335 172 0.012
response to radiation GO:0009314 151 0.012
sensory perception GO:0007600 103 0.012
sleep GO:0030431 2 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
regulation of t cell activation GO:0050863 77 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
response to external biotic stimulus GO:0043207 261 0.012
anatomical structure homeostasis GO:0060249 100 0.012
response to wounding GO:0009611 168 0.012
organelle assembly GO:0070925 176 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
negative regulation of organelle organization GO:0010639 126 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
immune effector process GO:0002252 159 0.012
regulation of protein maturation GO:1903317 150 0.012
positive regulation of cell motility GO:2000147 177 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
regulation of cell development GO:0060284 161 0.012
viral life cycle GO:0019058 132 0.012
sequestering of calcium ion GO:0051208 17 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
regulation of viral process GO:0050792 103 0.011
response to organonitrogen compound GO:0010243 156 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
calcium ion homeostasis GO:0055074 122 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
regulation of metal ion transport GO:0010959 120 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
dna repair GO:0006281 198 0.011
leukocyte activation GO:0045321 164 0.011
regulation of growth GO:0040008 165 0.011
sensory perception of pain GO:0019233 4 0.011
regulation of dna metabolic process GO:0051052 153 0.011
microtubule based process GO:0007017 210 0.011
cell division GO:0051301 168 0.011
compound eye development GO:0048749 1 0.011
sequestering of metal ion GO:0051238 24 0.011
protein localization to nucleus GO:0034504 136 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
protein import GO:0017038 130 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
positive regulation of proteolysis GO:0045862 142 0.011
nuclear import GO:0051170 106 0.011
response to metal ion GO:0010038 84 0.011
regulation of defense response GO:0031347 154 0.011
regulation of cell motility GO:2000145 299 0.011
t cell activation GO:0042110 99 0.011
myoblast fusion GO:0007520 1 0.010
negative regulation of secretion GO:0051048 58 0.010
visual behavior GO:0007632 2 0.010
cell activation GO:0001775 213 0.010
growth GO:0040007 202 0.010
stem cell division GO:0017145 2 0.010
regulation of peptidase activity GO:0052547 180 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
positive regulation of ras gtpase activity GO:0032320 117 0.010
tripartite regional subdivision GO:0007351 2 0.010
regulation of protein processing GO:0070613 150 0.010
exocytosis GO:0006887 71 0.010
response to oxygen levels GO:0070482 100 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.010
response to axon injury GO:0048678 1 0.010
actin cytoskeleton organization GO:0030036 207 0.010
positive regulation of cellular component movement GO:0051272 181 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
reproductive process GO:0022414 106 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010

PRDM9 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
eye and adnexa disease DOID:1492 150 0.017
eye disease DOID:5614 149 0.017
disease of metabolism DOID:0014667 295 0.017
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
organ system cancer DOID:0050686 164 0.015
retinal disease DOID:5679 118 0.015
musculoskeletal system disease DOID:17 223 0.013
central nervous system disease DOID:331 186 0.013
myopathy DOID:423 104 0.011
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011
neurodegenerative disease DOID:1289 102 0.010