Homo sapiens

0 known processes

PROP1

PROP paired-like homeobox 1

(Aliases: CPHD2)

PROP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
system process GO:0003008 349 0.167
cellular response to endogenous stimulus GO:0071495 336 0.099
secretion by cell GO:0032940 226 0.068
regulation of secretion GO:0051046 194 0.064
regulation of cellular component movement GO:0051270 334 0.064
secretion GO:0046903 254 0.060
cell adhesion GO:0007155 325 0.056
enzyme linked receptor protein signaling pathway GO:0007167 303 0.052
negative regulation of cell death GO:0060548 345 0.051
Mouse
post embryonic development GO:0009791 2 0.050
regulation of secretion by cell GO:1903530 177 0.048
regulation of cellular ketone metabolic process GO:0010565 50 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
mapk cascade GO:0000165 288 0.041
cellular response to growth factor stimulus GO:0071363 197 0.040
multicellular organismal aging GO:0010259 3 0.040
g protein coupled receptor signaling pathway GO:0007186 207 0.038
detection of stimulus GO:0051606 85 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.038
determination of adult lifespan GO:0008340 2 0.038
neurological system process GO:0050877 163 0.037
cellular amino acid metabolic process GO:0006520 116 0.037
response to oxygen containing compound GO:1901700 369 0.037
regulation of cell differentiation GO:0045595 393 0.036
organ morphogenesis GO:0009887 147 0.036
Mouse
response to growth factor GO:0070848 205 0.036
amine metabolic process GO:0009308 44 0.035
nitrogen compound transport GO:0071705 191 0.035
luteinizing hormone secretion GO:0032275 1 0.034
signal transduction by phosphorylation GO:0023014 297 0.034
response to abiotic stimulus GO:0009628 336 0.033
cellular ketone metabolic process GO:0042180 80 0.033
regulation of locomotion GO:0040012 329 0.032
cell cell signaling GO:0007267 155 0.031
positive regulation of phosphorylation GO:0042327 394 0.031
immune response GO:0006955 307 0.031
sensory perception GO:0007600 103 0.031
response to biotic stimulus GO:0009607 276 0.030
cell activation GO:0001775 213 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
response to nitrogen compound GO:1901698 184 0.030
regulation of cell cycle process GO:0010564 266 0.030
regulation of cell cycle GO:0051726 393 0.030
Human
positive regulation of transport GO:0051050 336 0.029
positive regulation of hydrolase activity GO:0051345 331 0.028
sensory perception of chemical stimulus GO:0007606 38 0.028
cytoplasmic transport GO:0016482 379 0.028
negative regulation of multicellular organismal process GO:0051241 317 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
regulation of protein kinase activity GO:0045859 289 0.027
segmentation GO:0035282 4 0.027
response to lipid GO:0033993 206 0.027
female gamete generation GO:0007292 2 0.027
biological adhesion GO:0022610 331 0.027
cation transport GO:0006812 331 0.027
neuropeptide signaling pathway GO:0007218 19 0.027
ion transmembrane transport GO:0034220 338 0.027
regulation of mapk cascade GO:0043408 262 0.026
lipid biosynthetic process GO:0008610 177 0.026
regulation of protein localization GO:0032880 296 0.026
membrane organization GO:0061024 292 0.026
organ formation GO:0048645 3 0.026
cellular amine metabolic process GO:0044106 41 0.025
regulation of protein transport GO:0051223 213 0.025
positive regulation of secretion by cell GO:1903532 108 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.025
Human Mouse
hormone secretion GO:0046879 65 0.025
cellular response to hormone stimulus GO:0032870 125 0.025
cation transmembrane transport GO:0098655 238 0.025
defense response GO:0006952 315 0.025
regulation of transferase activity GO:0051338 355 0.025
detection of chemical stimulus GO:0009593 55 0.025
negative regulation of secretion by cell GO:1903531 52 0.025
oogenesis GO:0048477 2 0.025
actin filament based process GO:0030029 224 0.025
single organism membrane organization GO:0044802 268 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
negative regulation of developmental process GO:0051093 247 0.024
positive regulation of protein phosphorylation GO:0001934 313 0.024
epithelial cell differentiation GO:0030855 141 0.024
positive regulation of cell differentiation GO:0045597 211 0.024
epithelium development GO:0060429 227 0.023
regulation of proteolysis GO:0030162 293 0.023
negative regulation of cell proliferation GO:0008285 228 0.023
vesicle mediated transport GO:0016192 371 0.023
nervous system development GO:0007399 293 0.023
Zebrafish Mouse Worm
negative regulation of cell differentiation GO:0045596 171 0.023
response to organic cyclic compound GO:0014070 204 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
cellular response to cytokine stimulus GO:0071345 181 0.022
protein catabolic process GO:0030163 325 0.022
Worm
regulation of system process GO:0044057 101 0.022
behavior GO:0007610 112 0.022
sensory perception of taste GO:0050909 36 0.022
positive regulation of developmental process GO:0051094 314 0.022
response to hormone GO:0009725 175 0.022
behavioral response to ethanol GO:0048149 2 0.022
small gtpase mediated signal transduction GO:0007264 78 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
lipid metabolic process GO:0006629 381 0.021
regulation of cell motility GO:2000145 299 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
Mouse
purine ribonucleotide catabolic process GO:0009154 404 0.020
central nervous system development GO:0007417 123 0.020
Zebrafish Mouse
positive regulation of secretion GO:0051047 116 0.020
response to cytokine GO:0034097 232 0.020
immune system development GO:0002520 195 0.020
monovalent inorganic cation transport GO:0015672 128 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
metal ion transport GO:0030001 272 0.020
rhythmic behavior GO:0007622 2 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
wnt signaling pathway GO:0016055 156 0.019
Mouse
response to other organism GO:0051707 261 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.019
cardiac muscle cell contraction GO:0086003 4 0.019
organophosphate catabolic process GO:0046434 430 0.019
response to external biotic stimulus GO:0043207 261 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
intracellular protein transport GO:0006886 270 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
mitotic cell cycle process GO:1903047 286 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
single organism cellular localization GO:1902580 332 0.018
negative regulation of cell migration GO:0030336 102 0.018
maintenance of location GO:0051235 112 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
anion transport GO:0006820 161 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
negative regulation of locomotion GO:0040013 118 0.018
hindbrain development GO:0030902 3 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
regulation of growth GO:0040008 165 0.018
regulation of kinase activity GO:0043549 314 0.017
protein oligomerization GO:0051259 173 0.017
cellular protein catabolic process GO:0044257 261 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
protein processing GO:0016485 226 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
negative regulation of cell motility GO:2000146 104 0.017
cellular lipid metabolic process GO:0044255 303 0.017
regulation of cell migration GO:0030334 289 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
ion homeostasis GO:0050801 230 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
regulation of reactive oxygen species metabolic process GO:2000377 41 0.017
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
regulation of leukocyte activation GO:0002694 115 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.016
ras protein signal transduction GO:0007265 73 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
positive regulation of kinase activity GO:0033674 204 0.016
multicellular organismal signaling GO:0035637 34 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
response to transforming growth factor beta GO:0071559 94 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
anterior posterior axis specification GO:0009948 2 0.016
protein maturation GO:0051604 233 0.016
anatomical structure homeostasis GO:0060249 100 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
single organism cell adhesion GO:0098602 179 0.016
blastoderm segmentation GO:0007350 2 0.016
cytokine production GO:0001816 247 0.016
transmembrane transport GO:0055085 399 0.016
hormone transport GO:0009914 68 0.016
lymphocyte activation GO:0046649 133 0.015
response to organonitrogen compound GO:0010243 156 0.015
regulation of immune response GO:0050776 201 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
mitotic cell cycle GO:0000278 326 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
positive regulation of cytokine production GO:0001819 167 0.015
neurogenesis GO:0022008 169 0.015
Worm
negative regulation of intracellular signal transduction GO:1902532 183 0.015
positive regulation of immune system process GO:0002684 283 0.015
positive regulation of transferase activity GO:0051347 227 0.015
head development GO:0060322 108 0.015
Zebrafish Mouse
negative regulation of programmed cell death GO:0043069 321 0.015
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
innate immune response GO:0045087 178 0.015
positive regulation of cell migration GO:0030335 172 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
positive regulation of cell cycle GO:0045787 140 0.015
circadian behavior GO:0048512 2 0.015
positive regulation of cell death GO:0010942 263 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
protein localization to organelle GO:0033365 280 0.015
cellular homeostasis GO:0019725 196 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
locomotory behavior GO:0007626 1 0.014
protein ubiquitination GO:0016567 314 0.014
regulation of intracellular transport GO:0032386 195 0.014
protein secretion GO:0009306 98 0.014
endomembrane system organization GO:0010256 196 0.014
dephosphorylation GO:0016311 209 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
cellular component morphogenesis GO:0032989 314 0.014
regulation of metal ion transport GO:0010959 120 0.014
spermatid differentiation GO:0048515 4 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
negative regulation of transport GO:0051051 176 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
epidermis morphogenesis GO:0048730 3 0.014
negative regulation of cell cycle GO:0045786 193 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
limbic system development GO:0021761 3 0.014
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.014
angiogenesis GO:0001525 147 0.014
regulation of cell activation GO:0050865 125 0.014
organic hydroxy compound metabolic process GO:1901615 147 0.014
response to virus GO:0009615 126 0.014
nucleotide catabolic process GO:0009166 408 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
response to drug GO:0042493 81 0.014
positive regulation of immune response GO:0050778 159 0.014
regulation of cell division GO:0051302 116 0.014
brain development GO:0007420 97 0.014
Zebrafish Mouse
cell development GO:0048468 328 0.014
cellular response to organic cyclic compound GO:0071407 127 0.014
negative regulation of secretion GO:0051048 58 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
negative regulation of protein modification process GO:0031400 200 0.013
tissue migration GO:0090130 119 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
lipid transport GO:0006869 90 0.013
regulation of hormone levels GO:0010817 125 0.013
regulation of response to external stimulus GO:0032101 222 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
reproductive process GO:0022414 106 0.013
growth GO:0040007 202 0.013
immune effector process GO:0002252 159 0.013
blood vessel morphogenesis GO:0048514 162 0.013
epithelial cell migration GO:0010631 119 0.013
cell cycle phase transition GO:0044770 173 0.013
blood circulation GO:0008015 113 0.013
positive regulation of protein transport GO:0051222 135 0.013
negative regulation of cellular component movement GO:0051271 106 0.013
oocyte development GO:0048599 1 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
cell projection organization GO:0030030 252 0.013
ribose phosphate biosynthetic process GO:0046390 82 0.013
leukocyte activation GO:0045321 164 0.013
protein localization to membrane GO:0072657 160 0.013
carbohydrate metabolic process GO:0005975 207 0.013
chemical homeostasis GO:0048878 306 0.013
mating GO:0007618 1 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
glycoprotein metabolic process GO:0009100 110 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
protein targeting GO:0006605 187 0.013
positive regulation of protein secretion GO:0050714 60 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
endocrine process GO:0050886 25 0.012
actin filament based movement GO:0030048 17 0.012
signal release GO:0023061 70 0.012
regulation of protein secretion GO:0050708 86 0.012
regulation of cell development GO:0060284 161 0.012
nucleotide biosynthetic process GO:0009165 109 0.012
dna repair GO:0006281 198 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
oocyte differentiation GO:0009994 2 0.012
organic hydroxy compound biosynthetic process GO:1901617 71 0.012
follicle stimulating hormone secretion GO:0046884 3 0.012
regulation of ion transport GO:0043269 189 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
adult locomotory behavior GO:0008344 1 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
circulatory system development GO:0072359 262 0.012
Mouse
cation homeostasis GO:0055080 189 0.012
action potential GO:0001508 34 0.012
heart development GO:0007507 95 0.012
positive regulation of cell motility GO:2000147 177 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
regulation of homeostatic process GO:0032844 121 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
spermatid development GO:0007286 4 0.012
small molecule biosynthetic process GO:0044283 157 0.012
tripartite regional subdivision GO:0007351 2 0.012
cell morphogenesis GO:0000902 296 0.012
epithelium migration GO:0090132 119 0.012
multicellular organismal homeostasis GO:0048871 67 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
nuclear transport GO:0051169 179 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
regeneration GO:0031099 4 0.012
response to radiation GO:0009314 151 0.012
regulation of protein complex assembly GO:0043254 147 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
cardiovascular system development GO:0072358 262 0.012
Mouse
regulation of hormone secretion GO:0046883 57 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
cell fate determination GO:0001709 3 0.011
atp metabolic process GO:0046034 176 0.011
cardiac muscle contraction GO:0060048 34 0.011
circulatory system process GO:0003013 113 0.011
regulation of ion transmembrane transporter activity GO:0032412 72 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.011
taxis GO:0042330 157 0.011
regulation of cellular response to stress GO:0080135 244 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
cell part morphogenesis GO:0032990 137 0.011
axis elongation GO:0003401 4 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
nucleoside catabolic process GO:0009164 408 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
developmental programmed cell death GO:0010623 3 0.011
blood vessel development GO:0001568 172 0.011
Mouse
negative regulation of immune system process GO:0002683 136 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
sequestering of calcium ion GO:0051208 17 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
cellular chemical homeostasis GO:0055082 180 0.011
ameboidal type cell migration GO:0001667 135 0.011
activation of immune response GO:0002253 114 0.011
positive regulation of proteolysis GO:0045862 142 0.011
mononuclear cell proliferation GO:0032943 71 0.011
regulation of cellular response to growth factor stimulus GO:0090287 76 0.011
apoptotic signaling pathway GO:0097190 268 0.011
response to steroid hormone GO:0048545 80 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
cell growth GO:0016049 160 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
cell division GO:0051301 168 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.011
metal ion homeostasis GO:0055065 169 0.011
muscle structure development GO:0061061 98 0.011
associative learning GO:0008306 1 0.011
negative regulation of protein transport GO:0051224 75 0.011
organic acid transport GO:0015849 65 0.011
neuromuscular junction development GO:0007528 3 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
purine containing compound catabolic process GO:0072523 411 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
organic anion transport GO:0015711 103 0.011
positive regulation of cell activation GO:0050867 81 0.011
epithelial cell proliferation GO:0050673 128 0.011
response to wounding GO:0009611 168 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
hemopoiesis GO:0030097 180 0.011
visual behavior GO:0007632 2 0.011
alcohol metabolic process GO:0006066 114 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
positive regulation of catabolic process GO:0009896 310 0.010
chromatin organization GO:0006325 351 0.010
regulation of transmembrane transporter activity GO:0022898 74 0.010
organic hydroxy compound transport GO:0015850 63 0.010
regulation of transporter activity GO:0032409 82 0.010
regulation of mitotic cell cycle phase transition GO:1901990 118 0.010
rna processing GO:0006396 255 0.010
actin filament organization GO:0007015 128 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
regulation of epithelial cell migration GO:0010632 93 0.010
single organismal cell cell adhesion GO:0016337 148 0.010
positive regulation of locomotion GO:0040017 186 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.010
protein localization to nucleus GO:0034504 136 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
response to bacterium GO:0009617 144 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
interspecies interaction between organisms GO:0044419 156 0.010
microtubule based process GO:0007017 210 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
ribonucleoside triphosphate metabolic process GO:0009199 412 0.010
amide transport GO:0042886 76 0.010

PROP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.027
sensory system disease DOID:0050155 203 0.024
Human
nervous system disease DOID:863 431 0.024
Human
immune system disease DOID:2914 155 0.023
disease of metabolism DOID:0014667 295 0.020
disease of cellular proliferation DOID:14566 174 0.017
eye and adnexa disease DOID:1492 150 0.016
Human
cancer DOID:162 167 0.015
retinal disease DOID:5679 118 0.015
Human
eye disease DOID:5614 149 0.015
Human
organ system cancer DOID:0050686 164 0.015
central nervous system disease DOID:331 186 0.015
hematopoietic system disease DOID:74 100 0.013
connective tissue disease DOID:65 109 0.012
neurodegenerative disease DOID:1289 102 0.011
bone disease DOID:0080001 88 0.010