Homo sapiens

5 known processes

NAF1

nuclear assembly factor 1 homolog (S. cerevisiae)

NAF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.210
snrna metabolic process GO:0016073 15 0.193
rna processing GO:0006396 255 0.130
female gamete generation GO:0007292 2 0.130
rrna modification GO:0000154 2 0.127
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.108
cellular ketone metabolic process GO:0042180 80 0.104
cellular amine metabolic process GO:0044106 41 0.098
amine metabolic process GO:0009308 44 0.086
cellular amino acid metabolic process GO:0006520 116 0.084
ribonucleoprotein complex biogenesis GO:0022613 116 0.084
regulation of peptidase activity GO:0052547 180 0.082
positive regulation of cell death GO:0010942 263 0.080
positive regulation of cellular component organization GO:0051130 376 0.077
positive regulation of cellular amine metabolic process GO:0033240 7 0.076
protein processing GO:0016485 226 0.074
regulation of endopeptidase activity GO:0052548 170 0.072
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.071
positive regulation of programmed cell death GO:0043068 249 0.069
protein maturation GO:0051604 233 0.064
regulation of cellular amine metabolic process GO:0033238 11 0.063
rna modification GO:0009451 27 0.062
protein localization to organelle GO:0033365 280 0.062
cd8 positive alpha beta t cell activation GO:0036037 3 0.061
regulation of cysteine type endopeptidase activity GO:2000116 127 0.060
regulation of cell cycle process GO:0010564 266 0.060
vesicle mediated transport GO:0016192 371 0.060
regulation of cellular amino acid metabolic process GO:0006521 6 0.057
multicellular organismal aging GO:0010259 3 0.056
zymogen activation GO:0031638 70 0.054
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.054
regulation of cellular component biogenesis GO:0044087 281 0.053
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.052
positive regulation of apoptotic process GO:0043065 246 0.051
t cell homeostasis GO:0043029 3 0.051
single organism cell adhesion GO:0098602 179 0.050
single organism cellular localization GO:1902580 332 0.050
determination of adult lifespan GO:0008340 2 0.049
regulation of cellular ketone metabolic process GO:0010565 50 0.048
cardiovascular system development GO:0072358 262 0.048
epithelial cell proliferation GO:0050673 128 0.047
cell adhesion GO:0007155 325 0.047
response to radiation GO:0009314 151 0.044
negative regulation of programmed cell death GO:0043069 321 0.043
ncrna metabolic process GO:0034660 108 0.043
positive regulation of cell proliferation GO:0008284 301 0.042
negative regulation of cell proliferation GO:0008285 228 0.042
growth GO:0040007 202 0.042
negative regulation of calcium ion transport into cytosol GO:0010523 3 0.041
rrna metabolic process GO:0016072 40 0.041
fear response GO:0042596 0 0.040
mitochondrion organization GO:0007005 156 0.039
positive regulation of apoptotic signaling pathway GO:2001235 70 0.039
positive regulation of cellular component biogenesis GO:0044089 158 0.038
response to abiotic stimulus GO:0009628 336 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
negative regulation of apoptotic process GO:0043066 316 0.037
response to axon injury GO:0048678 1 0.036
regulation of apoptotic signaling pathway GO:2001233 175 0.036
regulation of cell differentiation GO:0045595 393 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
positive regulation of endopeptidase activity GO:0010950 84 0.036
oxidation reduction process GO:0055114 396 0.036
single organismal cell cell adhesion GO:0016337 148 0.035
developmental programmed cell death GO:0010623 3 0.035
cellular component morphogenesis GO:0032989 314 0.034
tube development GO:0035295 125 0.034
covalent chromatin modification GO:0016569 254 0.034
positive regulation of mitochondrion organization GO:0010822 30 0.034
oocyte differentiation GO:0009994 2 0.034
negative regulation of protein modification process GO:0031400 200 0.034
behavioral defense response GO:0002209 0 0.034
hematopoietic or lymphoid organ development GO:0048534 186 0.033
mitochondrial membrane organization GO:0007006 40 0.033
postsynaptic membrane organization GO:0001941 2 0.033
regulation of meiotic cell cycle GO:0051445 4 0.033
organelle assembly GO:0070925 176 0.033
locomotory behavior GO:0007626 1 0.033
regulation of establishment of protein localization GO:0070201 242 0.032
circulatory system development GO:0072359 262 0.032
oocyte development GO:0048599 1 0.032
regulation of developmental pigmentation GO:0048070 2 0.032
lymphocyte homeostasis GO:0002260 4 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
mrna metabolic process GO:0016071 175 0.031
nervous system development GO:0007399 293 0.031
positive regulation of hydrolase activity GO:0051345 331 0.030
oogenesis GO:0048477 2 0.030
regulation of proteolysis GO:0030162 293 0.030
endocytosis GO:0006897 159 0.030
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.030
biological adhesion GO:0022610 331 0.030
positive regulation of cell differentiation GO:0045597 211 0.030
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.030
cellular response to organic cyclic compound GO:0071407 127 0.029
response to organic cyclic compound GO:0014070 204 0.029
cd8 positive alpha beta t cell differentiation GO:0043374 1 0.029
mitochondrial transport GO:0006839 60 0.029
protein ubiquitination GO:0016567 314 0.028
glycosyl compound catabolic process GO:1901658 413 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
defense response to virus GO:0051607 71 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
regulation of mitochondrion organization GO:0010821 54 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.026
regulation of multi organism process GO:0043900 157 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
cell type specific apoptotic process GO:0097285 125 0.026
response to lipid GO:0033993 206 0.025
response to hormone GO:0009725 175 0.024
negative regulation of locomotion GO:0040013 118 0.024
reactive oxygen species metabolic process GO:0072593 75 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
cellular lipid metabolic process GO:0044255 303 0.024
positive regulation of developmental process GO:0051094 314 0.024
apoptotic signaling pathway GO:0097190 268 0.023
apoptotic process involved in morphogenesis GO:0060561 3 0.023
positive regulation of organelle organization GO:0010638 195 0.023
cellular homeostasis GO:0019725 196 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
positive regulation of transport GO:0051050 336 0.023
histone modification GO:0016570 251 0.023
regulation of protein localization GO:0032880 296 0.023
rrna processing GO:0006364 35 0.023
negative regulation of transport GO:0051051 176 0.022
melanin metabolic process GO:0006582 1 0.022
ncrna processing GO:0034470 83 0.022
positive regulation of peptidase activity GO:0010952 88 0.022
regulation of cellular component movement GO:0051270 334 0.022
positive regulation of developmental pigmentation GO:0048087 2 0.022
nitrogen compound transport GO:0071705 191 0.022
embryo development GO:0009790 123 0.022
cellular response to external stimulus GO:0071496 111 0.021
protein catabolic process GO:0030163 325 0.021
regulation of epithelial cell proliferation GO:0050678 113 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
synaptic transmission cholinergic GO:0007271 2 0.021
transmembrane transport GO:0055085 399 0.021
hindbrain development GO:0030902 3 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
axon regeneration GO:0031103 1 0.020
chromatin organization GO:0006325 351 0.020
memory GO:0007613 3 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
negative regulation of protein metabolic process GO:0051248 391 0.020
cellular component assembly involved in morphogenesis GO:0010927 73 0.020
neuromuscular junction development GO:0007528 3 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
negative regulation of cellular component movement GO:0051271 106 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
lipid metabolic process GO:0006629 381 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
negative regulation of cell death GO:0060548 345 0.020
ras protein signal transduction GO:0007265 73 0.020
regulation of protein oligomerization GO:0032459 26 0.020
cell morphogenesis GO:0000902 296 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
protein oligomerization GO:0051259 173 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.019
segmentation GO:0035282 4 0.019
positive regulation of epithelial cell proliferation GO:0050679 65 0.019
response to oxygen containing compound GO:1901700 369 0.019
cell development GO:0048468 328 0.019
regulation of cell adhesion GO:0030155 166 0.019
defense response to other organism GO:0098542 129 0.019
response to virus GO:0009615 126 0.019
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 3 0.019
regulation of cell cycle GO:0051726 393 0.019
protein homooligomerization GO:0051260 100 0.019
regulation of cell motility GO:2000145 299 0.019
release of cytochrome c from mitochondria GO:0001836 35 0.019
activation of cysteine type endopeptidase activity GO:0097202 57 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
cell matrix adhesion GO:0007160 85 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
response to other organism GO:0051707 261 0.018
positive regulation of proteolysis GO:0045862 142 0.018
mitotic cell cycle GO:0000278 326 0.018
maturation of ssu rrna GO:0030490 3 0.018
cellular response to decreased oxygen levels GO:0036294 51 0.018
positive regulation of protein oligomerization GO:0032461 17 0.018
cell projection assembly GO:0030031 126 0.018
positive regulation of protein complex assembly GO:0031334 86 0.017
regeneration GO:0031099 4 0.017
immune system development GO:0002520 195 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
intracellular protein transport GO:0006886 270 0.017
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 2 0.017
neuron projection regeneration GO:0031102 1 0.017
ribonucleoprotein complex assembly GO:0022618 78 0.017
single organism membrane organization GO:0044802 268 0.017
anion transport GO:0006820 161 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
metal ion transport GO:0030001 272 0.017
defense response GO:0006952 315 0.017
peptidyl lysine modification GO:0018205 144 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
regulation of locomotion GO:0040012 329 0.016
epithelium development GO:0060429 227 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
nucleoside catabolic process GO:0009164 408 0.016
regulation of cell development GO:0060284 161 0.016
protein deubiquitination GO:0016579 79 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
organelle fission GO:0048285 149 0.016
metal ion homeostasis GO:0055065 169 0.016
actin filament based process GO:0030029 224 0.016
organophosphate catabolic process GO:0046434 430 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
negative regulation of cell motility GO:2000146 104 0.015
execution phase of apoptosis GO:0097194 32 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
pigment granule organization GO:0048753 7 0.015
mitotic cell cycle process GO:1903047 286 0.015
single organism reproductive process GO:0044702 98 0.015
negative regulation of organelle organization GO:0010639 126 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
membrane organization GO:0061024 292 0.015
regulation of meiosis GO:0040020 3 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
apoptotic mitochondrial changes GO:0008637 57 0.015
glycoprotein biosynthetic process GO:0009101 91 0.015
cellular response to hypoxia GO:0071456 51 0.015
cellular calcium ion homeostasis GO:0006874 117 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
epithelium migration GO:0090132 119 0.015
sensory perception of pain GO:0019233 4 0.015
reproductive process GO:0022414 106 0.015
positive regulation of cellular component movement GO:0051272 181 0.015
cellular protein complex assembly GO:0043623 188 0.015
receptor mediated endocytosis GO:0006898 84 0.015
hair follicle morphogenesis GO:0031069 2 0.014
t cell selection GO:0045058 4 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
regulation of cell substrate adhesion GO:0010810 68 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
regulation of intracellular transport GO:0032386 195 0.014
ossification GO:0001503 121 0.014
cellular response to lipid GO:0071396 127 0.014
rna splicing GO:0008380 131 0.014
developmental process involved in reproduction GO:0003006 66 0.014
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.014
cell substrate adhesion GO:0031589 132 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
blastoderm segmentation GO:0007350 2 0.014
cellular response to gonadotropin stimulus GO:0071371 4 0.014
reproduction GO:0000003 63 0.014
positive regulation of cell migration GO:0030335 172 0.014
oocyte maturation GO:0001556 1 0.014
cellular component disassembly GO:0022411 92 0.014
protein targeting GO:0006605 187 0.013
chemotaxis GO:0006935 157 0.013
purine containing compound catabolic process GO:0072523 411 0.013
post embryonic organ development GO:0048569 1 0.013
positive regulation of protein homooligomerization GO:0032464 7 0.013
cell growth GO:0016049 160 0.013
methylation GO:0032259 106 0.013
internal protein amino acid acetylation GO:0006475 101 0.013
myosin filament assembly GO:0031034 2 0.013
vasculature development GO:0001944 181 0.013
protein modification by small protein removal GO:0070646 92 0.013
regulation of protein kinase activity GO:0045859 289 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
response to external biotic stimulus GO:0043207 261 0.013
positive regulation of cytokine production GO:0001819 167 0.013
chromatin modification GO:0016568 298 0.013
cell cell signaling GO:0007267 155 0.013
calcium ion transport GO:0006816 147 0.013
response to estrogen GO:0043627 47 0.013
regulation of killing of cells of other organism GO:0051709 4 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
sequestering of calcium ion GO:0051208 17 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
regulation of protein processing GO:0070613 150 0.012
regulation of neuron apoptotic process GO:0043523 35 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 16 0.012
glycoprotein metabolic process GO:0009100 110 0.012
regulation of dna metabolic process GO:0051052 153 0.012
generation of neurons GO:0048699 152 0.012
small molecule biosynthetic process GO:0044283 157 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
cellular response to nutrient levels GO:0031669 69 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
compound eye development GO:0048749 1 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
positive regulation of cell development GO:0010720 92 0.012
stem cell division GO:0017145 2 0.012
spleen development GO:0048536 1 0.012
regulation of protein complex assembly GO:0043254 147 0.012
protein alkylation GO:0008213 74 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
regulation of sequestering of calcium ion GO:0051282 41 0.012
establishment of protein localization to mitochondrion GO:0072655 22 0.012
system process GO:0003008 349 0.012
lipid biosynthetic process GO:0008610 177 0.012
renal system development GO:0072001 63 0.012
response to hypoxia GO:0001666 96 0.012
protein acetylation GO:0006473 116 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
response to extracellular stimulus GO:0009991 85 0.012
homeostasis of number of cells GO:0048872 40 0.012
organic anion transport GO:0015711 103 0.012
head development GO:0060322 108 0.012
regulation of growth GO:0040008 165 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
immune response GO:0006955 307 0.012
thymocyte apoptotic process GO:0070242 2 0.012
maintenance of location GO:0051235 112 0.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.012
negative regulation of cell migration GO:0030336 102 0.012
sequestering of metal ion GO:0051238 24 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
cellular component disassembly involved in execution phase of apoptosis GO:0006921 13 0.011
carbohydrate metabolic process GO:0005975 207 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
cytokine production GO:0001816 247 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
multicellular organismal response to stress GO:0033555 1 0.011
regulation of chromosome organization GO:0033044 103 0.011
t cell activation GO:0042110 99 0.011
protein methylation GO:0006479 74 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 1 0.011
regulation of ion transport GO:0043269 189 0.011
generation of precursor metabolites and energy GO:0006091 68 0.011
divalent metal ion transport GO:0070838 152 0.011
organic acid biosynthetic process GO:0016053 97 0.011
positive regulation of smoothened signaling pathway GO:0045880 4 0.011
regulation of cellular response to stress GO:0080135 244 0.011
ribosome biogenesis GO:0042254 48 0.011
protein localization to membrane GO:0072657 160 0.011
organelle localization GO:0051640 84 0.011
response to metal ion GO:0010038 84 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
response to decreased oxygen levels GO:0036293 96 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
angiogenesis GO:0001525 147 0.011
cytoplasmic transport GO:0016482 379 0.011
cell division GO:0051301 168 0.011
cation transport GO:0006812 331 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
dna replication GO:0006260 116 0.011
negative regulation of cell growth GO:0030308 83 0.011
histone exchange GO:0043486 3 0.011
regulation of cell growth GO:0001558 135 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
protein localization to nucleus GO:0034504 136 0.011
epidermis morphogenesis GO:0048730 3 0.011
cilium organization GO:0044782 68 0.011
axonemal dynein complex assembly GO:0070286 11 0.011
taxis GO:0042330 157 0.011
myosin filament organization GO:0031033 2 0.011
negative regulation of peptidase activity GO:0010466 91 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
regulation of protein catabolic process GO:0042176 155 0.010
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
regulation of heart growth GO:0060420 4 0.010
cilium morphogenesis GO:0060271 75 0.010
regulation of response to external stimulus GO:0032101 222 0.010
regulation of cell migration GO:0030334 289 0.010
regulation of mitochondrial membrane permeability GO:0046902 25 0.010
striated muscle myosin thick filament assembly GO:0071688 2 0.010
cellular carbohydrate metabolic process GO:0044262 84 0.010
mitotic sister chromatid segregation GO:0000070 53 0.010
cellular cation homeostasis GO:0030003 163 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
cuticle development GO:0042335 1 0.010
histone h4 acetylation GO:0043967 47 0.010
visual behavior GO:0007632 2 0.010
negative regulation of protein binding GO:0032091 35 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010

NAF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.036
skin disease DOID:37 33 0.021
integumentary system disease DOID:16 43 0.021
disease of metabolism DOID:0014667 295 0.017
hematopoietic system disease DOID:74 100 0.016
sensory system disease DOID:0050155 203 0.015
nervous system disease DOID:863 431 0.015
musculoskeletal system disease DOID:17 223 0.015
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
inherited metabolic disorder DOID:655 242 0.011
connective tissue disease DOID:65 109 0.011
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011