|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.985
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.976
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.975
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.968
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.945
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.942
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.941
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.938
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.933
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.931
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.929
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.928
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.927
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.922
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.919
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.918
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.915
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.911
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.905
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.903
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.900
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.899
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.898
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.894
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.882
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.880
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.876
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.865
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.861
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.842
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.837
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.830
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.829
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.809
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.789
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.781
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.734
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.729
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.722
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.699
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.690
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.684
|
|
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.675
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.662
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.651
|
Fly |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.634
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.631
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.617
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.610
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.594
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.594
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.578
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.576
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.564
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.557
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.556
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.544
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.534
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.529
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.527
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.527
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.521
|
Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.518
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.517
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.513
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.510
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.502
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.501
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.494
|
|
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.483
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.467
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.463
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.433
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.431
|
Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.428
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.428
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.426
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.408
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.394
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.392
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.372
|
Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.369
|
Fly |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.355
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.355
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.345
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.338
|
Fly |
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.335
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.334
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.332
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.331
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.329
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.317
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.317
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.316
|
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.307
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.307
|
Human |
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.306
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.305
|
Fly |
|
|
response to peptide
|
GO:1901652 |
65 |
0.297
|
Fly |
|
|
cell competition in a multicellular organism
|
GO:0035212 |
1 |
0.293
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.289
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.288
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.288
|
Fly |
|
|
heart development
|
GO:0007507 |
95 |
0.288
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.285
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.284
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.282
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.281
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.276
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.276
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.275
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.275
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.271
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.267
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.267
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.264
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.260
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.259
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.259
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.258
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.254
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.253
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.249
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.244
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.244
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.243
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.242
|
|
|
|
positive regulation of cell junction assembly
|
GO:1901890 |
11 |
0.238
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.236
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.231
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.230
|
Fly |
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.226
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.223
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.222
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.220
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.211
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.205
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.205
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.203
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.203
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.201
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.201
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.195
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.193
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.192
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.192
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.192
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.188
|
Fly |
|
|
immune response
|
GO:0006955 |
307 |
0.186
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.186
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.180
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.179
|
|
|
|
system process
|
GO:0003008 |
349 |
0.172
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.168
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.166
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.164
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.163
|
Fly |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.162
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.162
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.161
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.157
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.157
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.155
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.151
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.149
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.148
|
Fly |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.145
|
Fly |
|
|
gland development
|
GO:0048732 |
48 |
0.144
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.144
|
Human |
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.141
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.139
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.139
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.139
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.138
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.137
|
Fly |
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.137
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.136
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.136
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.135
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.134
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.133
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.133
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.133
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.133
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.131
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.130
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.130
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.130
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.126
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.125
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.122
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.118
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.114
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.111
|
|
|
|
positive regulation of cardiac muscle cell differentiation
|
GO:2000727 |
4 |
0.111
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.110
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.108
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.107
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.106
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.104
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.104
|
Fly |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.104
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.104
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.102
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.101
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.101
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.100
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.097
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.097
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.096
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.095
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.094
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.094
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.093
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.092
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.092
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.092
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.091
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.090
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.089
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.088
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.086
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.085
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.084
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.084
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.084
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.083
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.083
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.083
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.081
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.080
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.080
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.080
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.079
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.079
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.079
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.078
|
Human |
|
|
regulation of hepatocyte proliferation
|
GO:2000345 |
1 |
0.078
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.078
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.077
|
Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.073
|
Fly |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.072
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.071
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.071
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.070
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.070
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.070
|
Fly |
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.069
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.069
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.069
|
|
|
|
protein localization to adherens junction
|
GO:0071896 |
2 |
0.069
|
|
|
|
growth
|
GO:0040007 |
202 |
0.069
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.069
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.068
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.068
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.067
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.066
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.066
|
|
|
|
positive regulation of integrin mediated signaling pathway
|
GO:2001046 |
2 |
0.065
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.065
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.065
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.063
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.062
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.062
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.061
|
|
|
|
hepatocyte proliferation
|
GO:0072574 |
1 |
0.061
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.060
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.060
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.059
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.059
|
|
|
|
regulation of cardiac muscle cell differentiation
|
GO:2000725 |
7 |
0.058
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.057
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.057
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.057
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.057
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.056
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.056
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.055
|
Fly |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.055
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.054
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.054
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.054
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.054
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.053
|
|
|
|
regulation of integrin mediated signaling pathway
|
GO:2001044 |
3 |
0.053
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.052
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.052
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.050
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.049
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.049
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.048
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.048
|
|
|
|
mating
|
GO:0007618 |
1 |
0.048
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.048
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.048
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.048
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.047
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.047
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.047
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.047
|
Mouse Fly |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.047
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.046
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.046
|
|
|
|
translation
|
GO:0006412 |
132 |
0.046
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.046
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.046
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.046
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.045
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.045
|
|
|
|
positive regulation of substrate adhesion dependent cell spreading
|
GO:1900026 |
15 |
0.045
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.044
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.044
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.043
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.043
|
|
|
|
memory
|
GO:0007613 |
3 |
0.043
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.043
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.043
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.043
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.042
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.042
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.042
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.042
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.042
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.041
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.041
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.041
|
|
|
|
endoplasmic reticulum tubular network organization
|
GO:0071786 |
8 |
0.041
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.041
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.041
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.041
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.041
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.041
|
|
|
|
rna transport
|
GO:0050658 |
39 |
0.041
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.041
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.040
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.040
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.040
|
Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.040
|
|
|
|
positive regulation of adherens junction organization
|
GO:1903393 |
12 |
0.039
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.039
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.039
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.039
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.038
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.038
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.038
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.037
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.037
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.037
|
|
|
|
regulation of rna splicing
|
GO:0043484 |
62 |
0.037
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.037
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.036
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.036
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.036
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.036
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.036
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.035
|
Human |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.035
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.035
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.035
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.035
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.034
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.034
|
Human |
|
|
regulation of substrate adhesion dependent cell spreading
|
GO:1900024 |
19 |
0.034
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.034
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.034
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.034
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.034
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.034
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.034
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.034
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.033
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.033
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.033
|
|
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
11 |
0.033
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.033
|
Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.033
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.033
|
Fly |
|
|
extracellular matrix disassembly
|
GO:0022617 |
16 |
0.033
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.033
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.032
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.032
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.032
|
Human |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.032
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.031
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.031
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.031
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.031
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.031
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.031
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.031
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.031
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.031
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.030
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.030
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.030
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.030
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.030
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.030
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.029
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.029
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.029
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.029
|
Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.029
|
|
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.029
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.029
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.029
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.029
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.029
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.029
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.029
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.029
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.029
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.028
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.028
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.028
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.028
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.028
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.028
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.028
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.028
|
Fly |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.028
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.028
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.028
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.028
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.028
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.027
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
7 |
0.027
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.027
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.027
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.027
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.027
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
90 |
0.027
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.027
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.026
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.026
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.026
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.026
|
|
|
|
smooth muscle cell matrix adhesion
|
GO:0061302 |
5 |
0.026
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.026
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.026
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.026
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.025
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.025
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.025
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.025
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.025
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.025
|
|
|
|
axoneme assembly
|
GO:0035082 |
3 |
0.025
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.024
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.024
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.024
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.023
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.023
|
Mouse |
|
|
rna polyadenylation
|
GO:0043631 |
14 |
0.023
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.023
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.023
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.023
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.023
|
|
|
|
epithelial cell proliferation involved in liver morphogenesis
|
GO:0072575 |
1 |
0.022
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.022
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.022
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.022
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.022
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.022
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.022
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.022
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.022
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.022
|
Fly |
|
|
dna conformation change
|
GO:0071103 |
113 |
0.022
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.022
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.022
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.021
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.021
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.021
|
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.021
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.021
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.021
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.021
|
|
|
|
establishment of rna localization
|
GO:0051236 |
39 |
0.021
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.021
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.020
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.020
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.020
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.020
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.020
|
|
|
|
regulation of glucocorticoid secretion
|
GO:2000849 |
4 |
0.020
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.020
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.020
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.020
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.020
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.020
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.020
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.020
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.020
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.019
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.019
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.019
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.019
|
Fly |
