Homo sapiens

173 known processes

NFE2L2

nuclear factor (erythroid-derived 2)-like 2

(Aliases: NRF2)

NFE2L2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein k33 linked ubiquitination GO:1990390 1 0.976
pharynx development GO:0060465 1 0.948
Fly
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.934
determination of adult lifespan GO:0008340 2 0.841
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.822
myeloid cell differentiation GO:0030099 117 0.810
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.793
negative regulation of erythrocyte differentiation GO:0045647 3 0.791
copii vesicle coating GO:0048208 2 0.771
chromosome passenger complex localization to spindle midzone GO:0035853 1 0.769
ubiquitin dependent protein catabolic process GO:0006511 206 0.769
vesicle targeting rough er to cis golgi GO:0048207 2 0.709
regulation of myeloid cell differentiation GO:0045637 81 0.698
epithelium development GO:0060429 227 0.686
protein modification by small protein conjugation GO:0032446 342 0.675
negative regulation of oxidative stress induced cell death GO:1903202 17 0.630
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.627
negative regulation of multicellular organismal process GO:0051241 317 0.600
hematopoietic or lymphoid organ development GO:0048534 186 0.589
cellular response to laminar fluid shear stress GO:0071499 5 0.571
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.558
Human
epidermal cell differentiation GO:0009913 45 0.551
cell cycle phase transition GO:0044770 173 0.531
Human
response to oxygen containing compound GO:1901700 369 0.530
flavonoid metabolic process GO:0009812 8 0.528
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.508
cellular response to oxidative stress GO:0034599 85 0.489
negative regulation of myeloid cell differentiation GO:0045638 42 0.482
distal tubule morphogenesis GO:0072156 3 0.476
regulation of cellular component biogenesis GO:0044087 281 0.472
Fly
protein catabolic process GO:0030163 325 0.465
intracellular mrna localization GO:0008298 1 0.461
Fly
erythrocyte homeostasis GO:0034101 31 0.453
tripartite regional subdivision GO:0007351 2 0.450
Fly
cellular macromolecule catabolic process GO:0044265 380 0.443
regulation of erythrocyte differentiation GO:0045646 17 0.439
regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0000117 1 0.436
Human
anterior posterior axis specification embryo GO:0008595 2 0.408
Fly
apoptotic signaling pathway GO:0097190 268 0.399
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.394
regulation of homeostatic process GO:0032844 121 0.394
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 8 0.383
Human
blastoderm segmentation GO:0007350 2 0.381
Fly
mitotic cell cycle process GO:1903047 286 0.379
Human
tube development GO:0035295 125 0.377
Fly
negative regulation of immune system process GO:0002683 136 0.369
sulfur compound metabolic process GO:0006790 101 0.365
segmentation GO:0035282 4 0.354
Fly
protein polyubiquitination GO:0000209 110 0.341
response to oxidative stress GO:0006979 121 0.339
post embryonic development GO:0009791 2 0.339
negative regulation of apoptotic signaling pathway GO:2001234 97 0.338
cellular response to cytokine stimulus GO:0071345 181 0.337
negative regulation of cellular response to oxidative stress GO:1900408 18 0.331
regulation of cell differentiation GO:0045595 393 0.330
Fly
multicellular organismal aging GO:0010259 3 0.322
Fly
regulation of epidermis development GO:0045682 19 0.320
regulation of cell cycle GO:0051726 393 0.315
regulation of cellular response to oxidative stress GO:1900407 26 0.314
erythrocyte differentiation GO:0030218 28 0.309
organ morphogenesis GO:0009887 147 0.302
vesicle targeting to from or within golgi GO:0048199 6 0.293
cellular response to hydrogen peroxide GO:0070301 37 0.292
endosomal transport GO:0016197 129 0.289
response to hydrogen peroxide GO:0042542 40 0.280
autophagic cell death GO:0048102 3 0.277
modification dependent protein catabolic process GO:0019941 209 0.277
negative regulation of cell death GO:0060548 345 0.263
system process GO:0003008 349 0.256
regulation of oxidative stress induced cell death GO:1903201 24 0.256
cellular response to fluid shear stress GO:0071498 7 0.254
mitotic cell cycle phase transition GO:0044772 162 0.253
Human
immune system development GO:0002520 195 0.247
epithelial cell differentiation GO:0030855 141 0.243
protein k48 linked ubiquitination GO:0070936 38 0.233
response to cytokine GO:0034097 232 0.231
microtubule cytoskeleton organization GO:0000226 176 0.227
Fly
membrane budding GO:0006900 28 0.226
second messenger mediated signaling GO:0019932 78 0.226
renal sodium ion transport GO:0003096 2 0.221
cell death in response to hydrogen peroxide GO:0036474 10 0.218
distal tubule development GO:0072017 4 0.204
regulation of cell maturation GO:1903429 3 0.202
Fly
regulation of cell cycle process GO:0010564 266 0.199
regulation of epithelial cell differentiation GO:0030856 24 0.193
protein ubiquitination GO:0016567 314 0.193
response to organic cyclic compound GO:0014070 204 0.191
microtubule based process GO:0007017 210 0.187
Fly
dicarboxylic acid metabolic process GO:0043648 29 0.184
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 7 0.180
Human
endomembrane system organization GO:0010256 196 0.177
epidermis development GO:0008544 59 0.162
cell cycle g2 m phase transition GO:0044839 43 0.157
Human
hemopoiesis GO:0030097 180 0.157
negative regulation of programmed cell death GO:0043069 321 0.157
cell morphogenesis GO:0000902 296 0.146
Fly
negative regulation of homeostatic process GO:0032845 59 0.146
response to hormone GO:0009725 175 0.142
metal ion transport GO:0030001 272 0.142
negative regulation of response to oxidative stress GO:1902883 18 0.141
ion homeostasis GO:0050801 230 0.138
cytokinesis GO:0000910 96 0.138
negative regulation of developmental process GO:0051093 247 0.136
single organism membrane budding GO:1902591 10 0.136
g2 m transition of mitotic cell cycle GO:0000086 41 0.136
Human
cell projection organization GO:0030030 252 0.135
Fly
wnt signaling pathway GO:0016055 156 0.135
protein processing GO:0016485 226 0.133
nervous system development GO:0007399 293 0.133
Fly
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.132
Fly
positive regulation of programmed cell death GO:0043068 249 0.131
modification dependent macromolecule catabolic process GO:0043632 212 0.131
negative regulation of cellular protein metabolic process GO:0032269 353 0.130
mitotic cell cycle GO:0000278 326 0.129
Human
cell type specific apoptotic process GO:0097285 125 0.122
skin development GO:0043588 76 0.116
vesicle organization GO:0016050 62 0.116
oocyte development GO:0048599 1 0.114
Fly
regulation of endothelial cell apoptotic process GO:2000351 24 0.112
regulation of cellular ketone metabolic process GO:0010565 50 0.111
kidney epithelium development GO:0072073 25 0.111
protein oligomerization GO:0051259 173 0.109
negative regulation of apoptotic process GO:0043066 316 0.109
protein maturation GO:0051604 233 0.109
cellular response to oxygen containing compound GO:1901701 276 0.106
maintenance of location GO:0051235 112 0.106
Fly
myeloid cell homeostasis GO:0002262 34 0.104
dorsal ventral axis specification GO:0009950 7 0.104
Fly
female gamete generation GO:0007292 2 0.102
Fly
head development GO:0060322 108 0.101
Fly
response to abiotic stimulus GO:0009628 336 0.097
Human
membrane organization GO:0061024 292 0.097
negative regulation of cell differentiation GO:0045596 171 0.096
positive regulation of cell death GO:0010942 263 0.095
secretion by cell GO:0032940 226 0.094
sodium ion transport GO:0006814 61 0.094
cellular component morphogenesis GO:0032989 314 0.090
Fly
regulation of proteolysis GO:0030162 293 0.090
regulation of hormone levels GO:0010817 125 0.089
cellular response to hypoxia GO:0071456 51 0.089
Human
renal system process GO:0003014 25 0.088
regulation of response to oxidative stress GO:1902882 26 0.087
cellular protein catabolic process GO:0044257 261 0.087
chemical homeostasis GO:0048878 306 0.087
cellular response to tumor necrosis factor GO:0071356 63 0.086
cellular response to organic cyclic compound GO:0071407 127 0.085
single organism cellular localization GO:1902580 332 0.085
Fly
positive regulation of hydrolase activity GO:0051345 331 0.083
response to inorganic substance GO:0010035 127 0.083
tube morphogenesis GO:0035239 95 0.082
monovalent inorganic cation transport GO:0015672 128 0.082
urogenital system development GO:0001655 65 0.082
intracellular protein transport GO:0006886 270 0.082
regulation of embryonic development GO:0045995 20 0.082
Mouse Fly
peptide hormone secretion GO:0030072 50 0.081
positive regulation of cellular component organization GO:0051130 376 0.080
lipid metabolic process GO:0006629 381 0.079
cation transport GO:0006812 331 0.079
cellular response to decreased oxygen levels GO:0036294 51 0.078
Human
oogenesis GO:0048477 2 0.076
Fly
regulation of hydrogen peroxide induced cell death GO:1903205 10 0.076
cell development GO:0048468 328 0.075
Fly
protein monoubiquitination GO:0006513 39 0.075
homeostasis of number of cells GO:0048872 40 0.074
translation GO:0006412 132 0.073
negative regulation of protein transport GO:0051224 75 0.073
kidney morphogenesis GO:0060993 19 0.072
cellular response to topologically incorrect protein GO:0035967 19 0.070
Mouse
necrotic cell death GO:0070265 21 0.069
hormone transport GO:0009914 68 0.068
cellular amino acid metabolic process GO:0006520 116 0.068
protein localization to organelle GO:0033365 280 0.068
negative regulation of protein metabolic process GO:0051248 391 0.067
amide transport GO:0042886 76 0.065
regulation of cell growth GO:0001558 135 0.064
positive regulation of catabolic process GO:0009896 310 0.063
response to metal ion GO:0010038 84 0.063
insulin secretion GO:0030073 39 0.062
chromatin organization GO:0006325 351 0.062
regulation of protein import into nucleus GO:0042306 78 0.062
regionalization GO:0003002 29 0.062
Fly
proteasomal protein catabolic process GO:0010498 176 0.062
peptidyl serine phosphorylation GO:0018105 101 0.061
response to oxygen levels GO:0070482 100 0.061
Human
embryo development GO:0009790 123 0.060
Mouse Fly
secretion GO:0046903 254 0.060
regulation of cell division GO:0051302 116 0.059
regulation of membrane potential GO:0042391 95 0.059
renal system development GO:0072001 63 0.059
regulation of epidermal cell differentiation GO:0045604 15 0.057
regulation of cytokinesis GO:0032465 45 0.057
negative regulation of intracellular signal transduction GO:1902532 183 0.056
nephron development GO:0072006 30 0.056
nephron epithelium morphogenesis GO:0072088 15 0.055
response to reactive oxygen species GO:0000302 61 0.055
aging GO:0007568 66 0.054
Fly
single organism membrane organization GO:0044802 268 0.054
morphogenesis of an epithelium GO:0002009 60 0.053
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.052
rna localization GO:0006403 41 0.051
Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.050
response to thyroid hormone GO:0097066 9 0.050
golgi vesicle transport GO:0048193 80 0.049
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.049
Fly
positive regulation of apoptotic process GO:0043065 246 0.049
hormone secretion GO:0046879 65 0.049
negative regulation of cell proliferation GO:0008285 228 0.049
regulation of kinase activity GO:0043549 314 0.048
cellular lipid metabolic process GO:0044255 303 0.048
positive regulation of apoptotic signaling pathway GO:2001235 70 0.048
regulation of oocyte development GO:0060281 1 0.048
Fly
peptide secretion GO:0002790 51 0.048
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.048
protein localization to cytoskeleton GO:0044380 11 0.047
patterning of blood vessels GO:0001569 2 0.047
cellular response to glucocorticoid stimulus GO:0071385 4 0.047
neuronal action potential GO:0019228 9 0.046
regulation of growth GO:0040008 165 0.046
positive regulation of cellular catabolic process GO:0031331 284 0.045
regulation of translation GO:0006417 89 0.045
translational initiation GO:0006413 48 0.045
covalent chromatin modification GO:0016569 254 0.045
post golgi vesicle mediated transport GO:0006892 36 0.045
establishment of organelle localization GO:0051656 59 0.044
bone mineralization GO:0030282 34 0.044
small molecule biosynthetic process GO:0044283 157 0.044
establishment of protein localization to organelle GO:0072594 172 0.042
ossification GO:0001503 121 0.042
regulation of myelination GO:0031641 1 0.042
peptide transport GO:0015833 74 0.042
chromatin modification GO:0016568 298 0.042
generation of neurons GO:0048699 152 0.042
Fly
regulation of anatomical structure size GO:0090066 101 0.041
regulation of protein processing GO:0070613 150 0.041
regulation of autophagy GO:0010506 52 0.041
chordate embryonic development GO:0043009 34 0.040
cell cycle g1 s phase transition GO:0044843 80 0.040
Human
renal tubule development GO:0061326 19 0.040
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.039
neuron development GO:0048666 113 0.039
Fly
regulation of protein localization GO:0032880 296 0.039
cellular ketone metabolic process GO:0042180 80 0.039
negative regulation of protein maturation GO:1903318 142 0.039
positive regulation of transport GO:0051050 336 0.038
nephron tubule development GO:0072080 17 0.038
protein localization to nucleus GO:0034504 136 0.038
positive regulation of developmental process GO:0051094 314 0.037
regulation of apoptotic signaling pathway GO:2001233 175 0.037
negative regulation of transport GO:0051051 176 0.037
memory GO:0007613 3 0.037
single organism reproductive process GO:0044702 98 0.037
Fly
regulation of mitotic cell cycle GO:0007346 189 0.037
posttranscriptional regulation of gene expression GO:0010608 213 0.037
cell morphogenesis involved in differentiation GO:0000904 144 0.036
Fly
vesicle mediated transport GO:0016192 371 0.036
amine metabolic process GO:0009308 44 0.036
vesicle targeting GO:0006903 7 0.035
neuron differentiation GO:0030182 138 0.035
Fly
regulation of cell development GO:0060284 161 0.035
Fly
neuron projection development GO:0031175 106 0.035
Fly
multicellular organismal signaling GO:0035637 34 0.035
regulation of system process GO:0044057 101 0.035
regulation of dna templated transcription in response to stress GO:0043620 18 0.035
positive regulation of cellular component biogenesis GO:0044089 158 0.034
positive regulation of autophagy GO:0010508 24 0.033
purine nucleoside triphosphate metabolic process GO:0009144 412 0.033
positive regulation of phosphorylation GO:0042327 394 0.033
regulation of intracellular transport GO:0032386 195 0.033
neurogenesis GO:0022008 169 0.033
Fly
epithelial tube morphogenesis GO:0060562 38 0.032
chondrocyte development GO:0002063 1 0.032
maintenance of protein location GO:0045185 57 0.032
negative regulation of translation GO:0017148 37 0.032
kidney development GO:0001822 53 0.032
mating GO:0007618 1 0.031
regulation of cellular component size GO:0032535 82 0.031
regulation of cysteine type endopeptidase activity GO:2000116 127 0.031
regulation of lipid metabolic process GO:0019216 96 0.031
nephron morphogenesis GO:0072028 15 0.031
regulation of nucleotide metabolic process GO:0006140 269 0.030
cellular amine metabolic process GO:0044106 41 0.030
protein autophosphorylation GO:0046777 123 0.030
response to decreased oxygen levels GO:0036293 96 0.030
Human
positive regulation of protein complex assembly GO:0031334 86 0.030
digestive system development GO:0055123 75 0.030
Fly
retina vasculature development in camera type eye GO:0061298 3 0.030
protein homooligomerization GO:0051260 100 0.030
positive regulation of protein catabolic process GO:0045732 75 0.030
positive regulation of secretion GO:0051047 116 0.030
rna processing GO:0006396 255 0.030
peptidyl serine modification GO:0018209 106 0.030
protein targeting GO:0006605 187 0.029
organelle localization GO:0051640 84 0.029
Fly
response to hypoxia GO:0001666 96 0.029
Human
autophagy GO:0006914 88 0.029
tissue morphogenesis GO:0048729 96 0.029
ion transmembrane transport GO:0034220 338 0.029
cell growth GO:0016049 160 0.029
negative regulation of cell growth GO:0030308 83 0.029
positive regulation of peptidase activity GO:0010952 88 0.029
nucleotide biosynthetic process GO:0009165 109 0.029
immune response GO:0006955 307 0.029
protein import GO:0017038 130 0.028
negative regulation of cytoplasmic transport GO:1903650 46 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
regulation of protein catabolic process GO:0042176 155 0.028
regulation of intracellular protein transport GO:0033157 123 0.028
signal release GO:0023061 70 0.027
regulation of protein targeting GO:1903533 91 0.027
maintenance of protein location in cell GO:0032507 56 0.027
regulation of peptidase activity GO:0052547 180 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
enzyme linked receptor protein signaling pathway GO:0007167 303 0.027
regulation of protein maturation GO:1903317 150 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
cytoplasmic transport GO:0016482 379 0.027
endoplasmic reticulum organization GO:0007029 20 0.027
cellular ion homeostasis GO:0006873 168 0.027
circadian behavior GO:0048512 2 0.026
morphogenesis of embryonic epithelium GO:0016331 4 0.026
rna splicing GO:0008380 131 0.026
negative regulation of proteolysis GO:0045861 132 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
response to tumor necrosis factor GO:0034612 76 0.025
maintenance of location in cell GO:0051651 62 0.025
Fly
organ formation GO:0048645 3 0.025
cell part morphogenesis GO:0032990 137 0.025
Fly
negative regulation of neurological system process GO:0031645 2 0.025
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.025
zymogen activation GO:0031638 70 0.024
cellular response to reactive oxygen species GO:0034614 50 0.024
nephron tubule morphogenesis GO:0072078 13 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
response to drug GO:0042493 81 0.024
nitric oxide mediated signal transduction GO:0007263 7 0.024
positive regulation of organelle organization GO:0010638 195 0.024
anterior posterior axis specification GO:0009948 2 0.024
Fly
lymphocyte homeostasis GO:0002260 4 0.024
response to unfolded protein GO:0006986 24 0.024
Mouse
regulation of neural precursor cell proliferation GO:2000177 4 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.023
positive regulation of secretion by cell GO:1903532 108 0.023
transmission of nerve impulse GO:0019226 11 0.023
cellular response to nitrogen compound GO:1901699 144 0.023
response to glucose GO:0009749 19 0.023
regulation of blood vessel size GO:0050880 18 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
response to nitrogen compound GO:1901698 184 0.022
lymphocyte activation GO:0046649 133 0.022
neurotransmitter secretion GO:0007269 4 0.022
regulation of reproductive process GO:2000241 15 0.022
Fly
embryonic hemopoiesis GO:0035162 4 0.022
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
nephron epithelium development GO:0072009 23 0.022
regulation of mitotic cell cycle phase transition GO:1901990 118 0.021
negative regulation of protein processing GO:0010955 142 0.021
negative regulation of growth GO:0045926 97 0.021
regulation of vesicle mediated transport GO:0060627 130 0.021
regulation of translational initiation GO:0006446 24 0.021
biomineral tissue development GO:0031214 39 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.020
regulation of cytokine production GO:0001817 232 0.020
negative regulation of intracellular transport GO:0032387 60 0.020
positive regulation of exocytosis GO:0045921 35 0.020
neurological system process GO:0050877 163 0.020
lactation GO:0007595 3 0.020
innate immune response GO:0045087 178 0.020
dna templated transcription initiation GO:0006352 35 0.020
endothelial cell apoptotic process GO:0072577 26 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.020
response to lipid GO:0033993 206 0.019
regulation of cell cycle phase transition GO:1901987 126 0.019
regulation of cellular response to stress GO:0080135 244 0.019
negative regulation of protein modification process GO:0031400 200 0.019
meiotic chromosome segregation GO:0045132 4 0.019
vascular process in circulatory system GO:0003018 29 0.019
chromosome segregation GO:0007059 114 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
negative regulation of peptidase activity GO:0010466 91 0.019
carboxylic acid biosynthetic process GO:0046394 97 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
blood vessel development GO:0001568 172 0.019
gland development GO:0048732 48 0.019
blood circulation GO:0008015 113 0.019
cell projection morphogenesis GO:0048858 129 0.019
Fly
single organism nuclear import GO:1902593 104 0.018
growth GO:0040007 202 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
vesicle coating GO:0006901 9 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
positive regulation of cell size GO:0045793 3 0.018
organophosphate catabolic process GO:0046434 430 0.018
protein import into nucleus GO:0006606 104 0.018
er to golgi vesicle mediated transport GO:0006888 19 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
regulation of protein complex assembly GO:0043254 147 0.018
biological adhesion GO:0022610 331 0.017
prostate gland development GO:0030850 3 0.017
cellular homeostasis GO:0019725 196 0.017
g1 s transition of mitotic cell cycle GO:0000082 78 0.017
Human
cellular amino acid biosynthetic process GO:0008652 30 0.017
neuroblast proliferation GO:0007405 4 0.017
organic acid biosynthetic process GO:0016053 97 0.017
response to organonitrogen compound GO:0010243 156 0.017
response to radiation GO:0009314 151 0.017
protein localization to membrane GO:0072657 160 0.017
response to biotic stimulus GO:0009607 276 0.017
regulation of cell activation GO:0050865 125 0.017
post embryonic organ development GO:0048569 1 0.017
transmembrane transport GO:0055085 399 0.017
histone modification GO:0016570 251 0.017
localization within membrane GO:0051668 14 0.017
regulation of growth rate GO:0040009 1 0.017
copii coated vesicle budding GO:0090114 5 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
regulation of rna splicing GO:0043484 62 0.016
cellular protein complex localization GO:0034629 8 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
associative learning GO:0008306 1 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.016
primary neural tube formation GO:0014020 3 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
cell division GO:0051301 168 0.016
negative regulation of protein localization to nucleus GO:1900181 34 0.016
mrna metabolic process GO:0016071 175 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
regulation of protein localization to nucleus GO:1900180 85 0.016
vesicle localization GO:0051648 26 0.016
interspecies interaction between organisms GO:0044419 156 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
syncytium formation by plasma membrane fusion GO:0000768 2 0.016
response to topologically incorrect protein GO:0035966 29 0.016
Mouse
fat cell differentiation GO:0045444 32 0.015
carbohydrate metabolic process GO:0005975 207 0.015
single organism cell adhesion GO:0098602 179 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
digestive tract development GO:0048565 75 0.015
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
nuclear import GO:0051170 106 0.015
metal ion homeostasis GO:0055065 169 0.015
regulation of transferase activity GO:0051338 355 0.015
negative regulation of endopeptidase activity GO:0010951 84 0.015
specification of organ identity GO:0010092 3 0.015
regulation of fatty acid metabolic process GO:0019217 24 0.015
nucleotide catabolic process GO:0009166 408 0.015
rhythmic behavior GO:0007622 2 0.015
neuron projection morphogenesis GO:0048812 50 0.015
Fly
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.015
meiosis i GO:0007127 4 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
positive regulation of immune system process GO:0002684 283 0.015
regulation of protein transport GO:0051223 213 0.015
regulation of neuroblast proliferation GO:1902692 3 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
mrna processing GO:0006397 133 0.014
developmental maturation GO:0021700 28 0.014
Fly
positive regulation of hormone biosynthetic process GO:0046886 4 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
morphogenesis of a polarized epithelium GO:0001738 3 0.014
cellular cation homeostasis GO:0030003 163 0.014
cellular amide metabolic process GO:0043603 69 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
positive regulation of neural precursor cell proliferation GO:2000179 2 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
protein dna complex subunit organization GO:0071824 80 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
dendrite development GO:0016358 24 0.014
Fly
regulation of binding GO:0051098 111 0.014
heart development GO:0007507 95 0.014
smooth muscle tissue development GO:0048745 3 0.014
response to estrogen GO:0043627 47 0.014
endocrine pancreas development GO:0031018 11 0.014
muscle cell cellular homeostasis GO:0046716 3 0.013
steroid metabolic process GO:0008202 94 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
peripheral nervous system development GO:0007422 2 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
eye development GO:0001654 42 0.013
response to nutrient levels GO:0031667 81 0.013
negative regulation of protein import into nucleus GO:0042308 30 0.013
circulatory system process GO:0003013 113 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
adult behavior GO:0030534 18 0.013
skeletal system development GO:0001501 79 0.013

NFE2L2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
eye and adnexa disease DOID:1492 150 0.022
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.017
eye disease DOID:5614 149 0.016