Homo sapiens

0 known processes

ZNF267

zinc finger protein 267

(Aliases: HZF2)

ZNF267 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.134
regulation of cellular amino acid metabolic process GO:0006521 6 0.129
purine nucleoside triphosphate metabolic process GO:0009144 412 0.122
amine metabolic process GO:0009308 44 0.111
cellular amine metabolic process GO:0044106 41 0.111
nucleoside triphosphate metabolic process GO:0009141 422 0.094
regulation of cellular ketone metabolic process GO:0010565 50 0.093
nucleosome positioning GO:0016584 3 0.090
purine nucleoside triphosphate catabolic process GO:0009146 392 0.086
determination of adult lifespan GO:0008340 2 0.085
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 0.085
organophosphate catabolic process GO:0046434 430 0.079
chromatin assembly GO:0031497 61 0.079
gtp metabolic process GO:0046039 239 0.077
dermatan sulfate proteoglycan biosynthetic process GO:0050651 4 0.076
purine ribonucleoside metabolic process GO:0046128 437 0.076
positive regulation of protein phosphorylation GO:0001934 313 0.074
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.071
cellular response to dna damage stimulus GO:0006974 379 0.071
ribonucleoside triphosphate catabolic process GO:0009203 391 0.070
multicellular organismal aging GO:0010259 3 0.069
response to cytokine GO:0034097 232 0.066
cellular ketone metabolic process GO:0042180 80 0.066
purine ribonucleotide catabolic process GO:0009154 404 0.065
purine ribonucleoside catabolic process GO:0046130 398 0.064
ribonucleoside catabolic process GO:0042454 406 0.062
protein modification by small protein conjugation GO:0032446 342 0.061
ribonucleotide catabolic process GO:0009261 405 0.061
ribonucleoside triphosphate metabolic process GO:0009199 412 0.060
purine containing compound catabolic process GO:0072523 411 0.059
glycosyl compound catabolic process GO:1901658 413 0.059
regulation of nucleoside metabolic process GO:0009118 209 0.058
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.058
nucleoside triphosphate catabolic process GO:0009143 394 0.057
carbohydrate derivative biosynthetic process GO:1901137 207 0.057
nucleoside phosphate catabolic process GO:1901292 412 0.054
protein dna complex subunit organization GO:0071824 80 0.054
nucleotide catabolic process GO:0009166 408 0.054
positive regulation of phosphorylation GO:0042327 394 0.054
purine nucleotide catabolic process GO:0006195 405 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
regulation of cellular response to stress GO:0080135 244 0.050
regulation of transferase activity GO:0051338 355 0.049
response to tumor necrosis factor GO:0034612 76 0.048
dna conformation change GO:0071103 113 0.047
regulation of cell cycle GO:0051726 393 0.047
innate immune response GO:0045087 178 0.046
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.045
post embryonic development GO:0009791 2 0.045
guanosine containing compound metabolic process GO:1901068 244 0.045
mitotic cell cycle process GO:1903047 286 0.044
chromatin organization GO:0006325 351 0.044
dna templated transcription initiation GO:0006352 35 0.044
purine nucleoside catabolic process GO:0006152 398 0.043
regulation of purine nucleotide metabolic process GO:1900542 264 0.043
regulation of cellular amine metabolic process GO:0033238 11 0.043
actin filament based process GO:0030029 224 0.042
cell projection organization GO:0030030 252 0.040
protein localization to organelle GO:0033365 280 0.040
small gtpase mediated signal transduction GO:0007264 78 0.038
organonitrogen compound biosynthetic process GO:1901566 200 0.038
positive regulation of secretion by cell GO:1903532 108 0.038
negative regulation of phosphate metabolic process GO:0045936 267 0.038
negative regulation of cellular amine metabolic process GO:0033239 3 0.037
peptidyl serine phosphorylation GO:0018105 101 0.036
immune response GO:0006955 307 0.036
regulation of nucleotide catabolic process GO:0030811 205 0.036
gtp catabolic process GO:0006184 237 0.036
immune response activating signal transduction GO:0002757 90 0.036
nucleoside catabolic process GO:0009164 408 0.035
endomembrane system organization GO:0010256 196 0.035
carbohydrate metabolic process GO:0005975 207 0.035
positive regulation of hydrolase activity GO:0051345 331 0.034
positive regulation of cellular component organization GO:0051130 376 0.034
cell morphogenesis GO:0000902 296 0.034
regulation of kinase activity GO:0043549 314 0.034
lipid metabolic process GO:0006629 381 0.034
dna replication GO:0006260 116 0.033
protein dna complex assembly GO:0065004 64 0.032
response to nitrogen compound GO:1901698 184 0.032
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.032
negative regulation of cell cycle GO:0045786 193 0.032
chromatin assembly or disassembly GO:0006333 78 0.032
cell cycle phase transition GO:0044770 173 0.032
single organism cellular localization GO:1902580 332 0.031
positive regulation of programmed cell death GO:0043068 249 0.031
anatomical structure formation involved in morphogenesis GO:0048646 284 0.031
segmentation GO:0035282 4 0.031
regulation of immune response GO:0050776 201 0.030
intrinsic apoptotic signaling pathway GO:0097193 127 0.030
mitotic cell cycle GO:0000278 326 0.030
regulation of mapk cascade GO:0043408 262 0.030
protein autophosphorylation GO:0046777 123 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
protein ubiquitination GO:0016567 314 0.030
regulation of purine nucleotide catabolic process GO:0033121 205 0.029
guanosine containing compound catabolic process GO:1901069 239 0.029
lipid biosynthetic process GO:0008610 177 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
regulation of cysteine type endopeptidase activity GO:2000116 127 0.029
nucleotide biosynthetic process GO:0009165 109 0.029
cellular lipid metabolic process GO:0044255 303 0.029
regulation of cellular component biogenesis GO:0044087 281 0.028
mitotic cell cycle phase transition GO:0044772 162 0.028
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.028
mapk cascade GO:0000165 288 0.028
activation of immune response GO:0002253 114 0.028
regulation of dna metabolic process GO:0051052 153 0.028
female gamete generation GO:0007292 2 0.028
cellular macromolecular complex assembly GO:0034622 324 0.028
oogenesis GO:0048477 2 0.027
hemopoiesis GO:0030097 180 0.027
positive regulation of gtp catabolic process GO:0033126 166 0.027
regulation of response to external stimulus GO:0032101 222 0.027
regulation of cell cycle process GO:0010564 266 0.026
negative regulation of cell death GO:0060548 345 0.026
modification dependent macromolecule catabolic process GO:0043632 212 0.026
positive regulation of cytokine production GO:0001819 167 0.026
sulfur compound metabolic process GO:0006790 101 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
regulation of mitotic cell cycle GO:0007346 189 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.025
negative regulation of cell cycle process GO:0010948 121 0.025
nucleosome organization GO:0034728 66 0.025
organophosphate biosynthetic process GO:0090407 163 0.025
regulation of vesicle mediated transport GO:0060627 130 0.025
regulation of leukocyte activation GO:0002694 115 0.025
protein targeting GO:0006605 187 0.025
intracellular protein transport GO:0006886 270 0.024
dephosphorylation GO:0016311 209 0.024
regulation of peptidase activity GO:0052547 180 0.024
leukocyte activation GO:0045321 164 0.024
positive regulation of cell death GO:0010942 263 0.024
fibroblast proliferation GO:0048144 33 0.024
positive regulation of kinase activity GO:0033674 204 0.024
chromatin modification GO:0016568 298 0.023
positive regulation of transport GO:0051050 336 0.023
response to other organism GO:0051707 261 0.023
histone exchange GO:0043486 3 0.023
actin cytoskeleton organization GO:0030036 207 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
Human
positive regulation of apoptotic process GO:0043065 246 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
response to oxygen containing compound GO:1901700 369 0.022
positive regulation of immune response GO:0050778 159 0.022
small molecule biosynthetic process GO:0044283 157 0.022
negative regulation of cell proliferation GO:0008285 228 0.022
erk1 and erk2 cascade GO:0070371 104 0.022
regulation of secretion by cell GO:1903530 177 0.022
glycoprotein metabolic process GO:0009100 110 0.022
nervous system development GO:0007399 293 0.021
regulation of cytokine production GO:0001817 232 0.021
secretion GO:0046903 254 0.021
syncytium formation by plasma membrane fusion GO:0000768 2 0.021
cilium morphogenesis GO:0060271 75 0.021
regulation of intracellular transport GO:0032386 195 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
cell type specific apoptotic process GO:0097285 125 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
regulation of proteolysis GO:0030162 293 0.021
lymphocyte activation GO:0046649 133 0.021
nitrogen compound transport GO:0071705 191 0.021
neuron differentiation GO:0030182 138 0.020
chondroitin sulfate proteoglycan metabolic process GO:0050654 10 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
regulation of meiotic cell cycle GO:0051445 4 0.020
system process GO:0003008 349 0.020
epithelium development GO:0060429 227 0.020
cilium organization GO:0044782 68 0.020
hemostasis GO:0007599 76 0.020
response to oxidative stress GO:0006979 121 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
vesicle organization GO:0016050 62 0.020
cytokine mediated signaling pathway GO:0019221 109 0.020
defense response GO:0006952 315 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.019
regulation of protein stability GO:0031647 87 0.019
vesicle mediated transport GO:0016192 371 0.019
secretion by cell GO:0032940 226 0.019
cell activation GO:0001775 213 0.019
regulation of transcription by chromatin organization GO:0034401 1 0.019
glycerolipid biosynthetic process GO:0045017 51 0.019
positive regulation of defense response GO:0031349 87 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
peptide transport GO:0015833 74 0.018
negative regulation of immune system process GO:0002683 136 0.018
response to organonitrogen compound GO:0010243 156 0.018
regulation of interferon beta biosynthetic process GO:0045357 4 0.018
peptidyl tyrosine dephosphorylation GO:0035335 36 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
regulation of response to dna damage stimulus GO:2001020 94 0.018
protein maturation GO:0051604 233 0.018
positive regulation of transferase activity GO:0051347 227 0.018
protein polyubiquitination GO:0000209 110 0.018
coagulation GO:0050817 78 0.018
response to biotic stimulus GO:0009607 276 0.018
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.018
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.018
regulation of binding GO:0051098 111 0.018
g protein coupled receptor signaling pathway GO:0007186 207 0.018
skin development GO:0043588 76 0.018
regulation of fibroblast proliferation GO:0048145 32 0.018
positive regulation of secretion GO:0051047 116 0.018
positive regulation of immune system process GO:0002684 283 0.018
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.018
response to wounding GO:0009611 168 0.018
cellular response to oxidative stress GO:0034599 85 0.018
negative regulation of protein modification process GO:0031400 200 0.017
regulation of cell motility GO:2000145 299 0.017
plasma membrane organization GO:0007009 115 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
cation transmembrane transport GO:0098655 238 0.017
cell projection assembly GO:0030031 126 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
cell adhesion GO:0007155 325 0.017
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.017
covalent chromatin modification GO:0016569 254 0.017
microtubule based process GO:0007017 210 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
Human
cytoplasmic transport GO:0016482 379 0.017
neurogenesis GO:0022008 169 0.017
histone modification GO:0016570 251 0.017
protein oligomerization GO:0051259 173 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
exocytosis GO:0006887 71 0.017
associative learning GO:0008306 1 0.016
t cell differentiation in thymus GO:0033077 4 0.016
cellular protein catabolic process GO:0044257 261 0.016
regulation of cell differentiation GO:0045595 393 0.016
proteoglycan metabolic process GO:0006029 29 0.016
maintenance of location GO:0051235 112 0.016
organelle assembly GO:0070925 176 0.016
glycoprotein biosynthetic process GO:0009101 91 0.016
regulation of secretion GO:0051046 194 0.016
nucleoside monophosphate metabolic process GO:0009123 191 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
neurotransmitter secretion GO:0007269 4 0.016
immune effector process GO:0002252 159 0.016
lymphocyte homeostasis GO:0002260 4 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
apoptotic signaling pathway GO:0097190 268 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
ion transmembrane transport GO:0034220 338 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
biological adhesion GO:0022610 331 0.015
cell part morphogenesis GO:0032990 137 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
negative regulation of transferase activity GO:0051348 124 0.015
cilium assembly GO:0042384 63 0.015
sulfur compound biosynthetic process GO:0044272 38 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
single organism cell adhesion GO:0098602 179 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
regulation of chromosome organization GO:0033044 103 0.015
regulation of meiosis GO:0040020 3 0.015
response to abiotic stimulus GO:0009628 336 0.015
leukocyte differentiation GO:0002521 98 0.015
neuroblast proliferation GO:0007405 4 0.015
blood coagulation GO:0007596 76 0.014
coenzyme metabolic process GO:0006732 65 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
wnt signaling pathway GO:0016055 156 0.014
cell projection morphogenesis GO:0048858 129 0.014
negative regulation of transport GO:0051051 176 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
neuron development GO:0048666 113 0.014
protein processing GO:0016485 226 0.014
neurological system process GO:0050877 163 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
convergent extension GO:0060026 1 0.014
cellular component morphogenesis GO:0032989 314 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
negative regulation of cell growth GO:0030308 83 0.014
negative regulation of organelle organization GO:0010639 126 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.014
cellular response to external stimulus GO:0071496 111 0.014
glycerophospholipid metabolic process GO:0006650 84 0.014
calcium ion transport GO:0006816 147 0.014
single organism membrane organization GO:0044802 268 0.014
regulation of mitotic cell cycle phase transition GO:1901990 118 0.014
cell cycle g1 s phase transition GO:0044843 80 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
protein catabolic process GO:0030163 325 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
response to lipid GO:0033993 206 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
regulation of synaptic vesicle exocytosis GO:2000300 2 0.013
histone acetylation GO:0016573 93 0.013
wound healing GO:0042060 115 0.013
response to external biotic stimulus GO:0043207 261 0.013
positive regulation of catabolic process GO:0009896 310 0.013
organic acid biosynthetic process GO:0016053 97 0.013
phospholipid metabolic process GO:0006644 99 0.013
chemical homeostasis GO:0048878 306 0.013
cell growth GO:0016049 160 0.013
spermatid development GO:0007286 4 0.013
protein stabilization GO:0050821 64 0.013
somitogenesis GO:0001756 2 0.013
regulation of cellular component movement GO:0051270 334 0.013
regulation of protein kinase activity GO:0045859 289 0.013
regulation of protein maturation GO:1903317 150 0.013
response to fungus GO:0009620 4 0.013
nucleosome assembly GO:0006334 50 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
carboxylic acid biosynthetic process GO:0046394 97 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
jnk cascade GO:0007254 80 0.012
epithelial cell differentiation GO:0030855 141 0.012
cation transport GO:0006812 331 0.012
actin filament based movement GO:0030048 17 0.012
head development GO:0060322 108 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
dna packaging GO:0006323 77 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
regulation of protein transport GO:0051223 213 0.012
rap protein signal transduction GO:0032486 7 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
ras protein signal transduction GO:0007265 73 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
regulation of cell division GO:0051302 116 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
actin mediated cell contraction GO:0070252 12 0.012
actin filament bundle organization GO:0061572 54 0.012
negative regulation of kinase activity GO:0033673 106 0.012
atp metabolic process GO:0046034 176 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
translation GO:0006412 132 0.012
Human
regulation of atp metabolic process GO:1903578 29 0.012
positive regulation of exocytosis GO:0045921 35 0.012
calcium ion transmembrane transport GO:0070588 76 0.012
glycolipid metabolic process GO:0006664 27 0.012
negative regulation of binding GO:0051100 57 0.011
protein localization to nucleus GO:0034504 136 0.011
oocyte differentiation GO:0009994 2 0.011
t cell receptor signaling pathway GO:0050852 21 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
g2 m transition of mitotic cell cycle GO:0000086 41 0.011
methylation GO:0032259 106 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
phosphatidylinositol metabolic process GO:0046488 53 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
cellular response to glucocorticoid stimulus GO:0071385 4 0.011
regulation of gtpase activity GO:0043087 180 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
vasodilation GO:0042311 4 0.011
regulation of cell projection organization GO:0031344 107 0.011
response to hormone GO:0009725 175 0.011
glycolipid biosynthetic process GO:0009247 12 0.011
generation of neurons GO:0048699 152 0.011
response to organic cyclic compound GO:0014070 204 0.011
morphogenesis of an epithelium GO:0002009 60 0.011
protein homooligomerization GO:0051260 100 0.011
immune system development GO:0002520 195 0.011
central nervous system development GO:0007417 123 0.011
positive regulation of protein transport GO:0051222 135 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
regulation of leukocyte differentiation GO:1902105 61 0.011
rna processing GO:0006396 255 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
regulation of locomotion GO:0040012 329 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
blastocyst development GO:0001824 3 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
transmembrane transport GO:0055085 399 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
regulation of interleukin 1 mediated signaling pathway GO:2000659 3 0.010
cell division GO:0051301 168 0.010
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
cytokine production GO:0001816 247 0.010
response to interleukin 1 GO:0070555 47 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
positive regulation of cell size GO:0045793 3 0.010
morphogenesis of a polarized epithelium GO:0001738 3 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.010
positive regulation of endopeptidase activity GO:0010950 84 0.010
signal transduction by p53 class mediator GO:0072331 72 0.010
regulation of cell activation GO:0050865 125 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.010
cellular component assembly involved in morphogenesis GO:0010927 73 0.010
regulation of erk1 and erk2 cascade GO:0070372 99 0.010

ZNF267 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.023
eye and adnexa disease DOID:1492 150 0.023
nervous system disease DOID:863 431 0.023
eye disease DOID:5614 149 0.023
musculoskeletal system disease DOID:17 223 0.020
connective tissue disease DOID:65 109 0.020
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.019
retinal disease DOID:5679 118 0.018
retinal degeneration DOID:8466 89 0.018
immune system disease DOID:2914 155 0.012
disease of metabolism DOID:0014667 295 0.012
retinitis pigmentosa DOID:10584 51 0.011
hematopoietic system disease DOID:74 100 0.010
inherited metabolic disorder DOID:655 242 0.010