|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
1.000
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
1.000
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
1.000
|
Rat |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
1.000
|
Rat |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
1.000
|
Rat |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
1.000
|
Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.999
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.999
|
Rat |
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.999
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.999
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.999
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.999
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.999
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.999
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.999
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.998
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.998
|
Rat |
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.998
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.998
|
Fly |
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.997
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.997
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.997
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.997
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.996
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.996
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.996
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.995
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.994
|
Rat |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.994
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.993
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.992
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.992
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.990
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.989
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.989
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.989
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.988
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.987
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.987
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.987
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.986
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.986
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.985
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.985
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.984
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.984
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.984
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.983
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.983
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.982
|
Fly |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.982
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.978
|
Rat |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.977
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.976
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.976
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.975
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.974
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.973
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.973
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.973
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.971
|
Fly |
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.971
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.970
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.969
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.969
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.967
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.966
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.966
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.966
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.964
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.962
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.961
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.957
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.954
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.953
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.953
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.952
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.952
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.950
|
Fly |
|
|
response to hormone
|
GO:0009725 |
175 |
0.949
|
Rat |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.948
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.947
|
Rat |
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.946
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.941
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.941
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.939
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.939
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.938
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.938
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.938
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.932
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.932
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.930
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.920
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.914
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.913
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.913
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.908
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.907
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.901
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.900
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.899
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.898
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.897
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.895
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.895
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.890
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.890
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.890
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.889
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.881
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.881
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.877
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.876
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.875
|
Fly |
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.868
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.867
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.867
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.865
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.864
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.863
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.863
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.861
|
Rat |
|
|
positive regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010641 |
2 |
0.861
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.861
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.860
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.859
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.858
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.855
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.851
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.851
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.851
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.849
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.845
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.843
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.837
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.829
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.829
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.829
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.827
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.820
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.819
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.814
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.810
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.810
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.801
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.795
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.795
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.795
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.792
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.792
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.789
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.788
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.787
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.787
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.785
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.785
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.781
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.779
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.777
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.775
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.774
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.773
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.772
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.771
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.768
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.766
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.759
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.757
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.757
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.756
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.755
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.752
|
Rat |
|
|
negative regulation of type i interferon mediated signaling pathway
|
GO:0060339 |
4 |
0.738
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.738
|
|
|
|
positive regulation of vasodilation
|
GO:0045909 |
4 |
0.735
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.734
|
Rat |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.734
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.730
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.729
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.729
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.728
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.728
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.727
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.727
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.711
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.710
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.709
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.708
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.703
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.703
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.697
|
|
|
|
neurotrophin signaling pathway
|
GO:0038179 |
8 |
0.696
|
Rat |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.696
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.694
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.692
|
Rat |
|
|
platelet derived growth factor receptor beta signaling pathway
|
GO:0035791 |
4 |
0.687
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.686
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.686
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.681
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.680
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.668
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.667
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.666
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.664
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.662
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.661
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.657
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.657
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.655
|
Fly |
|
|
ossification
|
GO:0001503 |
121 |
0.651
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.642
|
|
|
|
replacement ossification
|
GO:0036075 |
1 |
0.641
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.634
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.632
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.629
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.629
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.625
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.622
|
|
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.618
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.614
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.593
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.591
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.590
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.589
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.589
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.588
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.582
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.582
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.578
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.578
|
Rat |
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.573
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.567
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.565
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.562
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.561
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.558
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.556
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.556
|
|
|
|
regulation of vasodilation
|
GO:0042312 |
4 |
0.553
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.551
|
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.551
|
|
|
|
positive regulation of adherens junction organization
|
GO:1903393 |
12 |
0.549
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.546
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.542
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.541
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.540
|
Rat |
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.537
|
|
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
19 |
0.536
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.531
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.526
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.517
|
|
|
|
regulation of cgmp mediated signaling
|
GO:0010752 |
1 |
0.517
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.515
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.514
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.512
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.508
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.507
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
8 |
0.506
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.502
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.491
|
|
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
27 |
0.481
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.479
|
|
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.475
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.473
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.472
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.470
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.466
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.465
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.462
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.456
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
1 |
0.456
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.454
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.453
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.453
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.453
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.446
|
|
|
|
growth
|
GO:0040007 |
202 |
0.441
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.437
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.434
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.432
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.430
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.427
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.426
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.424
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.421
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.420
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.420
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.420
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
4 |
0.418
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.417
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.415
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.415
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.407
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.405
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.403
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.403
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.396
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.395
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.394
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.391
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.389
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.386
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.385
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.381
|
|
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.381
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.378
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.377
|
|
|
|
negative regulation of insulin like growth factor receptor signaling pathway
|
GO:0043569 |
4 |
0.374
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
3 |
0.374
|
|
|
|
positive regulation of oxidoreductase activity
|
GO:0051353 |
26 |
0.366
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.363
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.362
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.360
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.359
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.358
|
|
|
|
endochondral ossification
|
GO:0001958 |
1 |
0.357
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.356
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.352
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.350
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.350
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.349
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.347
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.346
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.344
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.343
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.343
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.342
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.342
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.341
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.340
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.339
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.338
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.337
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.329
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.325
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.317
|
|
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.313
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.312
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.311
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.307
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.306
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.305
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.304
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.301
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.297
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.287
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.286
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.286
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.284
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.282
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.281
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.280
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.280
|
|
|
|
positive regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000096 |
2 |
0.279
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.274
|
|
|
|
positive regulation of cell junction assembly
|
GO:1901890 |
11 |
0.273
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.273
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.272
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.265
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.264
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.263
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.261
|
|
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.261
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.260
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.259
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.258
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.255
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.254
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.252
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
6 |
0.250
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.249
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.248
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.246
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.244
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.242
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.239
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.238
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.234
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.233
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.231
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.231
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.230
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.229
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.228
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.226
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.225
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.218
|
|
|
|
response to ph
|
GO:0009268 |
12 |
0.217
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.217
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.217
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.215
|
|
|
|
response to acidic ph
|
GO:0010447 |
5 |
0.214
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.214
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.211
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
14 |
0.208
|
Mouse |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.206
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.206
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.205
|
|
|
|
dendritic spine development
|
GO:0060996 |
6 |
0.205
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.204
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.203
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.202
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.200
|
|
|
|
transcytosis
|
GO:0045056 |
1 |
0.200
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.199
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.198
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.198
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.197
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.196
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.196
|
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.194
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.194
|
|
|
|
regulation of interleukin 6 mediated signaling pathway
|
GO:0070103 |
3 |
0.192
|
|
|
|
natural killer cell activation
|
GO:0030101 |
12 |
0.192
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.191
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.190
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.190
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
3 |
0.187
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.186
|
Fly |
|
|
taurine metabolic process
|
GO:0019530 |
1 |
0.185
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.183
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.181
|
|
|
|
clathrin mediated endocytosis
|
GO:0072583 |
8 |
0.181
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.180
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.180
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.180
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.179
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.177
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.174
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.174
|
|
|
|
branched chain amino acid metabolic process
|
GO:0009081 |
4 |
0.173
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.172
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.172
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.171
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
2 |
0.170
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.167
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.163
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.160
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.159
|
|
|
|
lymphangiogenesis
|
GO:0001946 |
7 |
0.159
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.159
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.155
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.155
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.154
|
|
|
|
regulation of inositol trisphosphate biosynthetic process
|
GO:0032960 |
1 |
0.153
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.152
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.152
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.151
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.151
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.150
|
|
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.150
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.150
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.150
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.145
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.145
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.143
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.143
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.142
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.142
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.142
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.141
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.139
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.138
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.137
|
|
|
|
establishment or maintenance of neuroblast polarity
|
GO:0045196 |
1 |
0.135
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.135
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.133
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.133
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.133
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.132
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.131
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.131
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
11 |
0.131
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.130
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.130
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.129
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.128
|
|
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.126
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.125
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.123
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.121
|
|
|
|
regulation of metalloenzyme activity
|
GO:0048552 |
3 |
0.121
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.121
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.120
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.119
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.119
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.118
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.116
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.116
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.116
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.113
|
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.112
|
|
