Homo sapiens

0 known processes

PI4KB

phosphatidylinositol 4-kinase, catalytic, beta

(Aliases: FLJ30129,PI4KIIIBETA,PI4K-BETA,DKFZp686O1820,PI4KBETA,PIK4CB,NPIK,PI4K92)

PI4KB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 78 0.352
ras protein signal transduction GO:0007265 73 0.218
single organism cellular localization GO:1902580 332 0.130
single organism membrane organization GO:0044802 268 0.121
glycosyl compound catabolic process GO:1901658 413 0.116
purine containing compound catabolic process GO:0072523 411 0.109
locomotory behavior GO:0007626 1 0.101
membrane organization GO:0061024 292 0.092
regulation of ras protein signal transduction GO:0046578 155 0.088
somatic muscle development GO:0007525 1 0.078
purine ribonucleotide catabolic process GO:0009154 404 0.077
segmentation GO:0035282 4 0.074
regulation of cell differentiation GO:0045595 393 0.074
axon cargo transport GO:0008088 2 0.071
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.068
regulation of cell cycle GO:0051726 393 0.067
nervous system development GO:0007399 293 0.067
ribonucleoside catabolic process GO:0042454 406 0.066
nucleoside triphosphate metabolic process GO:0009141 422 0.059
regulation of rab gtpase activity GO:0032313 39 0.058
organophosphate catabolic process GO:0046434 430 0.058
inorganic ion transmembrane transport GO:0098660 231 0.056
regulation of small gtpase mediated signal transduction GO:0051056 156 0.056
cell development GO:0048468 328 0.056
purine ribonucleoside metabolic process GO:0046128 437 0.055
regulation of cellular component biogenesis GO:0044087 281 0.055
ribonucleoside triphosphate metabolic process GO:0009199 412 0.055
ribonucleotide catabolic process GO:0009261 405 0.054
gtp catabolic process GO:0006184 237 0.054
neuromuscular junction development GO:0007528 3 0.054
cell projection organization GO:0030030 252 0.054
blastoderm segmentation GO:0007350 2 0.053
positive regulation of ras gtpase activity GO:0032320 117 0.052
multicellular organismal aging GO:0010259 3 0.050
endomembrane system organization GO:0010256 196 0.049
regulation of nucleoside metabolic process GO:0009118 209 0.049
positive regulation of catabolic process GO:0009896 310 0.048
oogenesis GO:0048477 2 0.047
gtp metabolic process GO:0046039 239 0.046
ribonucleoside triphosphate catabolic process GO:0009203 391 0.045
regulation of rab protein signal transduction GO:0032483 39 0.045
nucleoside triphosphate catabolic process GO:0009143 394 0.045
monovalent inorganic cation transport GO:0015672 128 0.044
regulation of ras gtpase activity GO:0032318 128 0.044
cellular lipid metabolic process GO:0044255 303 0.044
Yeast Rat
cell cell signaling GO:0007267 155 0.044
purine nucleoside triphosphate catabolic process GO:0009146 392 0.043
cytoplasmic transport GO:0016482 379 0.043
system process GO:0003008 349 0.043
amine metabolic process GO:0009308 44 0.042
determination of adult lifespan GO:0008340 2 0.042
purine nucleotide catabolic process GO:0006195 405 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.042
cell morphogenesis GO:0000902 296 0.042
protein localization to membrane GO:0072657 160 0.042
positive regulation of rab gtpase activity GO:0032851 39 0.042
negative regulation of protein metabolic process GO:0051248 391 0.042
cellular component disassembly GO:0022411 92 0.041
regulation of synaptic plasticity GO:0048167 3 0.041
regulation of protein localization GO:0032880 296 0.040
metal ion transport GO:0030001 272 0.039
regulation of purine nucleotide metabolic process GO:1900542 264 0.039
cellular component morphogenesis GO:0032989 314 0.039
nucleotide catabolic process GO:0009166 408 0.038
memory GO:0007613 3 0.038
associative learning GO:0008306 1 0.037
purine nucleoside triphosphate metabolic process GO:0009144 412 0.037
cellular macromolecule catabolic process GO:0044265 380 0.037
neurogenesis GO:0022008 169 0.037
transmembrane transport GO:0055085 399 0.037
sodium ion transmembrane transport GO:0035725 59 0.036
potassium ion transport GO:0006813 62 0.036
anterior posterior axis specification GO:0009948 2 0.036
regulation of gtpase activity GO:0043087 180 0.036
lipid metabolic process GO:0006629 381 0.036
Yeast Rat
protein catabolic process GO:0030163 325 0.036
guanosine containing compound catabolic process GO:1901069 239 0.035
positive regulation of gtpase activity GO:0043547 166 0.035
cellular ketone metabolic process GO:0042180 80 0.035
nucleoside catabolic process GO:0009164 408 0.034
regulation of growth GO:0040008 165 0.033
positive regulation of hydrolase activity GO:0051345 331 0.033
regulation of nucleotide catabolic process GO:0030811 205 0.033
microtubule based process GO:0007017 210 0.033
purine nucleoside catabolic process GO:0006152 398 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.033
negative regulation of locomotion GO:0040013 118 0.033
neuron differentiation GO:0030182 138 0.033
regulation of establishment of protein localization GO:0070201 242 0.032
neurological system process GO:0050877 163 0.032
regulation of purine nucleotide catabolic process GO:0033121 205 0.032
protein localization to plasma membrane GO:0072659 93 0.032
rab protein signal transduction GO:0032482 4 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
long term memory GO:0007616 2 0.031
signal transduction by phosphorylation GO:0023014 297 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.030
cation transmembrane transport GO:0098655 238 0.030
protein processing GO:0016485 226 0.029
anterior posterior axis specification embryo GO:0008595 2 0.029
regulation of secretion GO:0051046 194 0.029
rna processing GO:0006396 255 0.029
microtubule cytoskeleton organization GO:0000226 176 0.029
positive regulation of phosphorylation GO:0042327 394 0.029
regulation of proteolysis GO:0030162 293 0.029
posttranscriptional regulation of gene expression GO:0010608 213 0.029
negative regulation of apoptotic process GO:0043066 316 0.028
positive regulation of transport GO:0051050 336 0.028
nucleus localization GO:0051647 1 0.028
actin filament based process GO:0030029 224 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
establishment of protein localization to membrane GO:0090150 121 0.028
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.027
autophagy GO:0006914 88 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
generation of neurons GO:0048699 152 0.027
plasma membrane organization GO:0007009 115 0.027
visual behavior GO:0007632 2 0.026
positive regulation of gtp catabolic process GO:0033126 166 0.026
growth GO:0040007 202 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
establishment of nucleus localization GO:0040023 1 0.026
organ morphogenesis GO:0009887 147 0.026
intracellular protein transport GO:0006886 270 0.026
negative regulation of developmental process GO:0051093 247 0.026
signal release GO:0023061 70 0.026
negative regulation of multicellular organismal process GO:0051241 317 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
behavior GO:0007610 112 0.026
regulation of cell morphogenesis GO:0022604 153 0.026
covalent chromatin modification GO:0016569 254 0.026
positive regulation of cellular component organization GO:0051130 376 0.025
rho protein signal transduction GO:0007266 26 0.025
oocyte differentiation GO:0009994 2 0.025
protein maturation GO:0051604 233 0.025
mitochondrion organization GO:0007005 156 0.025
cell fate determination GO:0001709 3 0.025
cellular amine metabolic process GO:0044106 41 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
cell morphogenesis involved in differentiation GO:0000904 144 0.024
inorganic cation transmembrane transport GO:0098662 194 0.024
cellular response to endogenous stimulus GO:0071495 336 0.024
basement membrane organization GO:0071711 3 0.024
canonical wnt signaling pathway GO:0060070 116 0.024
cell substrate adhesion GO:0031589 132 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
chromatin modification GO:0016568 298 0.023
negative regulation of protein modification process GO:0031400 200 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
nucleoside phosphate catabolic process GO:1901292 412 0.023
mapk cascade GO:0000165 288 0.023
regulation of cell development GO:0060284 161 0.023
atp metabolic process GO:0046034 176 0.023
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.022
chemical homeostasis GO:0048878 306 0.022
neurotransmitter secretion GO:0007269 4 0.022
regulation of protein transport GO:0051223 213 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
cellular response to external stimulus GO:0071496 111 0.022
cellular response to nitrogen compound GO:1901699 144 0.022
rna splicing GO:0008380 131 0.022
cell projection morphogenesis GO:0048858 129 0.022
positive regulation of synaptic transmission GO:0050806 4 0.022
spermatid differentiation GO:0048515 4 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
ion transmembrane transport GO:0034220 338 0.021
post embryonic development GO:0009791 2 0.021
negative regulation of cellular component movement GO:0051271 106 0.021
nuclear migration GO:0007097 1 0.021
regulation of cellular protein catabolic process GO:1903362 96 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.021
visual learning GO:0008542 1 0.021
enzyme linked receptor protein signaling pathway GO:0007167 303 0.021
response to external biotic stimulus GO:0043207 261 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.021
lipid modification GO:0030258 84 0.021
Yeast Rat
response to oxygen containing compound GO:1901700 369 0.020
spermatid development GO:0007286 4 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
cellular protein catabolic process GO:0044257 261 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
mrna metabolic process GO:0016071 175 0.020
somatic stem cell maintenance GO:0035019 4 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
biological adhesion GO:0022610 331 0.020
tripartite regional subdivision GO:0007351 2 0.020
ion homeostasis GO:0050801 230 0.020
cellular response to nutrient levels GO:0031669 69 0.020
defense response GO:0006952 315 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
establishment of protein localization to plasma membrane GO:0090002 68 0.020
inositol lipid mediated signaling GO:0048017 55 0.020
nuclear transport GO:0051169 179 0.019
circadian behavior GO:0048512 2 0.019
regulation of protein catabolic process GO:0042176 155 0.019
positive regulation of cell death GO:0010942 263 0.019
regulation of cell growth GO:0001558 135 0.019
regulation of protein kinase activity GO:0045859 289 0.019
regulation of transferase activity GO:0051338 355 0.019
protein targeting GO:0006605 187 0.019
response to other organism GO:0051707 261 0.019
neuron projection development GO:0031175 106 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
vesicle mediated transport GO:0016192 371 0.019
regulation of cell motility GO:2000145 299 0.019
regulation of secretion by cell GO:1903530 177 0.018
organelle assembly GO:0070925 176 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
regulation of hormone levels GO:0010817 125 0.018
cellular amino acid metabolic process GO:0006520 116 0.018
regulation of kinase activity GO:0043549 314 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.018
cellular homeostasis GO:0019725 196 0.018
oxidation reduction process GO:0055114 396 0.018
protein targeting to nucleus GO:0044744 104 0.018
negative regulation of organelle organization GO:0010639 126 0.018
negative regulation of cell migration GO:0030336 102 0.018
cellular response to starvation GO:0009267 58 0.018
actin cytoskeleton organization GO:0030036 207 0.018
regulation of mapk cascade GO:0043408 262 0.018
regulation of intracellular transport GO:0032386 195 0.018
negative regulation of catabolic process GO:0009895 104 0.018
secretion by cell GO:0032940 226 0.018
chemotaxis GO:0006935 157 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
regulation of autophagy GO:0010506 52 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
nerve development GO:0021675 4 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.017
cell growth GO:0016049 160 0.017
lipid biosynthetic process GO:0008610 177 0.017
endosomal transport GO:0016197 129 0.017
positive regulation of developmental process GO:0051094 314 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
innate immune response GO:0045087 178 0.016
maintenance of location GO:0051235 112 0.016
negative regulation of cell motility GO:2000146 104 0.016
immune response GO:0006955 307 0.016
carbohydrate metabolic process GO:0005975 207 0.016
response to nitrogen compound GO:1901698 184 0.016
oocyte development GO:0048599 1 0.016
cell cycle checkpoint GO:0000075 117 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
central nervous system development GO:0007417 123 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
cranial nerve development GO:0021545 4 0.016
atp catabolic process GO:0006200 157 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
negative regulation of transferase activity GO:0051348 124 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
cognition GO:0050890 43 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
cation transport GO:0006812 331 0.015
embryonic morphogenesis GO:0048598 85 0.015
epithelial cell differentiation GO:0030855 141 0.015
eye photoreceptor cell differentiation GO:0001754 2 0.015
long term synaptic potentiation GO:0060291 1 0.015
response to abiotic stimulus GO:0009628 336 0.015
chromatin organization GO:0006325 351 0.015
negative regulation of protein kinase activity GO:0006469 98 0.015
neuron development GO:0048666 113 0.015
cell adhesion GO:0007155 325 0.015
regulation of neurotransmitter secretion GO:0046928 3 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
peptidyl lysine modification GO:0018205 144 0.015
regulation of defense response GO:0031347 154 0.015
cell division GO:0051301 168 0.015
protein localization to organelle GO:0033365 280 0.015
positive regulation of hormone biosynthetic process GO:0046886 4 0.015
regulation of cellular response to stress GO:0080135 244 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
cytoskeleton dependent intracellular transport GO:0030705 21 0.014
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
macromolecular complex disassembly GO:0032984 60 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
histone modification GO:0016570 251 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
regulation of homeostatic process GO:0032844 121 0.014
negative regulation of kinase activity GO:0033673 106 0.014
rhythmic behavior GO:0007622 2 0.014
peripheral nervous system development GO:0007422 2 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
microtubule organizing center organization GO:0031023 62 0.014
internal protein amino acid acetylation GO:0006475 101 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
regulation of ion transport GO:0043269 189 0.014
negative regulation of protein maturation GO:1903318 142 0.014
regulation of immune response GO:0050776 201 0.014
wnt signaling pathway GO:0016055 156 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
single organism nuclear import GO:1902593 104 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
response to starvation GO:0042594 59 0.014
regulation of response to external stimulus GO:0032101 222 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
regulation of cytokine production GO:0001817 232 0.014
cell part morphogenesis GO:0032990 137 0.014
single organism reproductive process GO:0044702 98 0.014
regulation of cell migration GO:0030334 289 0.014
positive regulation of organ growth GO:0046622 2 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.014
regulation of protein maturation GO:1903317 150 0.013
negative regulation of growth GO:0045926 97 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
macroautophagy GO:0016236 39 0.013
regulation of cell projection organization GO:0031344 107 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
endocytosis GO:0006897 159 0.013
intracellular mrna localization GO:0008298 1 0.013
protein ubiquitination GO:0016567 314 0.013
response to nutrient levels GO:0031667 81 0.013
positive regulation of protein catabolic process GO:0045732 75 0.013
taxis GO:0042330 157 0.013
regulation of metal ion transport GO:0010959 120 0.013
regulation of innate immune response GO:0045088 97 0.013
response to extracellular stimulus GO:0009991 85 0.013
nitrogen compound transport GO:0071705 191 0.013
regulation of synaptic vesicle exocytosis GO:2000300 2 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.013
regulation of protein processing GO:0070613 150 0.012
sodium ion transport GO:0006814 61 0.012
mitotic cell cycle GO:0000278 326 0.012
organelle localization GO:0051640 84 0.012
positive regulation of immune system process GO:0002684 283 0.012
regulation of proteasomal protein catabolic process GO:0061136 87 0.012
meiotic chromosome segregation GO:0045132 4 0.012
positive regulation of proteolysis GO:0045862 142 0.012
neuroblast proliferation GO:0007405 4 0.012
protein acylation GO:0043543 138 0.012
positive regulation of defense response GO:0031349 87 0.012
synaptic transmission GO:0007268 61 0.012
regeneration GO:0031099 4 0.012
phospholipid metabolic process GO:0006644 99 0.012
Yeast Rat
response to biotic stimulus GO:0009607 276 0.012
regulation of translation GO:0006417 89 0.012
regulation of anatomical structure size GO:0090066 101 0.012
apoptotic signaling pathway GO:0097190 268 0.012
female gamete generation GO:0007292 2 0.012
regulation of multi organism process GO:0043900 157 0.012
protein stabilization GO:0050821 64 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
regulation of protein complex assembly GO:0043254 147 0.012
response to organonitrogen compound GO:0010243 156 0.012
regulation of protein stability GO:0031647 87 0.012
vesicle transport along microtubule GO:0047496 4 0.012
negative regulation of transport GO:0051051 176 0.012
positive regulation of autophagy GO:0010508 24 0.012
chromosome segregation GO:0007059 114 0.012
negative regulation of immune system process GO:0002683 136 0.012
retrograde transport endosome to golgi GO:0042147 45 0.012
regulation of membrane potential GO:0042391 95 0.012
cytokine production GO:0001816 247 0.012
regulation of nervous system development GO:0051960 88 0.012
regulation of synaptic vesicle transport GO:1902803 3 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.011
reproductive process GO:0022414 106 0.011
internal peptidyl lysine acetylation GO:0018393 97 0.011
organ formation GO:0048645 3 0.011
hindbrain development GO:0030902 3 0.011
limbic system development GO:0021761 3 0.011
regulation of cellular component movement GO:0051270 334 0.011
regulation of neurogenesis GO:0050767 82 0.011
activation of immune response GO:0002253 114 0.011
negative regulation of protein processing GO:0010955 142 0.011
embryo development GO:0009790 123 0.011
nuclear division GO:0000280 128 0.011
rna interference GO:0016246 4 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
synaptic vesicle endocytosis GO:0048488 2 0.011
regulation of cell maturation GO:1903429 3 0.011
defense response to other organism GO:0098542 129 0.011
regulation of actin filament based process GO:0032970 141 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
cdc42 protein signal transduction GO:0032488 4 0.011
potassium ion transmembrane transport GO:0071805 60 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
establishment of organelle localization GO:0051656 59 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
response to fungus GO:0009620 4 0.011
regulation of neuron projection development GO:0010975 57 0.011
regulation of transmembrane transport GO:0034762 139 0.011
endosome organization GO:0007032 20 0.011
protein localization to nucleus GO:0034504 136 0.010
central nervous system neuron axonogenesis GO:0021955 3 0.010
neuronal stem cell division GO:0036445 1 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
regulation of cellular component size GO:0032535 82 0.010
negative regulation of cell cycle GO:0045786 193 0.010
action potential GO:0001508 34 0.010
motor neuron axon guidance GO:0008045 2 0.010
cellular chemical homeostasis GO:0055082 180 0.010
mitochondrion distribution GO:0048311 3 0.010
rna splicing via transesterification reactions GO:0000375 90 0.010
protein complex disassembly GO:0043241 52 0.010
protein modification by small protein removal GO:0070646 92 0.010
regulation of cell substrate adhesion GO:0010810 68 0.010
negative regulation of cell death GO:0060548 345 0.010
translation GO:0006412 132 0.010
centrosome organization GO:0051297 58 0.010
erk1 and erk2 cascade GO:0070371 104 0.010
response to hormone GO:0009725 175 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
nuclear import GO:0051170 106 0.010

PI4KB disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.024
disease of metabolism DOID:0014667 295 0.015
cardiovascular system disease DOID:1287 106 0.015
disease of mental health DOID:150 70 0.012
musculoskeletal system disease DOID:17 223 0.011
sensory system disease DOID:0050155 203 0.010
nervous system disease DOID:863 431 0.010
neuropathy DOID:870 52 0.010