Homo sapiens

47 known processes

NDC80

NDC80 homolog, kinetochore complex component (S. cerevisiae)

(Aliases: HEC1,KNTC2,hsNDC80,TID3,HEC)

NDC80 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome segregation GO:0007059 114 0.982
mitotic nuclear division GO:0007067 119 0.973
Worm
organelle fission GO:0048285 149 0.946
Worm
microtubule cytoskeleton organization GO:0000226 176 0.941
mitotic sister chromatid segregation GO:0000070 53 0.937
Worm
microtubule based process GO:0007017 210 0.913
mitotic spindle organization GO:0007052 27 0.896
mitotic cell cycle process GO:1903047 286 0.887
nuclear division GO:0000280 128 0.822
Worm
sister chromatid segregation GO:0000819 54 0.815
Worm
spindle assembly checkpoint GO:0071173 17 0.786
regulation of microtubule cytoskeleton organization GO:0070507 61 0.762
negative regulation of chromosome organization GO:2001251 48 0.670
spindle organization GO:0007051 53 0.661
spindle stabilization GO:0043146 4 0.653
mitotic cell cycle GO:0000278 326 0.637
mitotic spindle assembly checkpoint GO:0007094 14 0.540
maintenance of protein location GO:0045185 57 0.538
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.490
protein depolymerization GO:0051261 30 0.455
maintenance of location in cell GO:0051651 62 0.447
negative regulation of organelle organization GO:0010639 126 0.439
regulation of mitosis GO:0007088 63 0.419
single organism cellular localization GO:1902580 332 0.381
attachment of spindle microtubules to kinetochore GO:0008608 17 0.377
microtubule polymerization or depolymerization GO:0031109 37 0.374
negative regulation of mitotic cell cycle GO:0045930 102 0.369
regulation of mitotic sister chromatid segregation GO:0033047 27 0.368
regulation of cell cycle GO:0051726 393 0.364
spindle assembly involved in mitosis GO:0090307 12 0.330
spindle assembly GO:0051225 29 0.289
protein localization to chromosome centromeric region GO:0071459 12 0.212
negative regulation of cell cycle GO:0045786 193 0.200
spindle midzone assembly GO:0051255 4 0.199
regulation of cell cycle process GO:0010564 266 0.177
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.174
regulation of chromosome segregation GO:0051983 44 0.169
mitotic spindle checkpoint GO:0071174 18 0.168
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.166
protein localization to organelle GO:0033365 280 0.158
regulation of protein localization GO:0032880 296 0.141
somatic stem cell division GO:0048103 1 0.136
microtubule based movement GO:0007018 32 0.134
regulation of cytoskeleton organization GO:0051493 177 0.127
positive regulation of programmed cell death GO:0043068 249 0.126
mitotic sister chromatid separation GO:0051306 18 0.120
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.118
protein dna complex subunit organization GO:0071824 80 0.114
regulation of protein catabolic process GO:0042176 155 0.113
regulation of cell cycle phase transition GO:1901987 126 0.113
negative regulation of sister chromatid segregation GO:0033046 17 0.109
organelle localization GO:0051640 84 0.108
circulatory system development GO:0072359 262 0.107
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.098
regulation of proteolysis GO:0030162 293 0.097
negative regulation of cell division GO:0051782 31 0.089
meiotic chromosome segregation GO:0045132 4 0.085
spindle elongation GO:0051231 4 0.084
cellular protein complex assembly GO:0043623 188 0.082
positive regulation of cellular protein catabolic process GO:1903364 37 0.081
cardiovascular system development GO:0072358 262 0.081
negative regulation of cellular component organization GO:0051129 235 0.076
proteasomal protein catabolic process GO:0010498 176 0.076
chromosome separation GO:0051304 23 0.076
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.070
organelle assembly GO:0070925 176 0.068
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.067
positive regulation of catabolic process GO:0009896 310 0.066
nucleus localization GO:0051647 1 0.065
nucleoside triphosphate metabolic process GO:0009141 422 0.065
apoptotic signaling pathway GO:0097190 268 0.065
heart development GO:0007507 95 0.064
cell division GO:0051301 168 0.064
cellular macromolecular complex assembly GO:0034622 324 0.063
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.057
negative regulation of cell cycle process GO:0010948 121 0.056
regulation of mitotic sister chromatid separation GO:0010965 27 0.056
regulation of cell division GO:0051302 116 0.055
regulation of proteasomal protein catabolic process GO:0061136 87 0.055
embryo development GO:0009790 123 0.053
Worm
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.053
modification dependent protein catabolic process GO:0019941 209 0.052
cellular component disassembly GO:0022411 92 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.050
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.045
negative regulation of chromosome segregation GO:0051985 18 0.044
microtubule organizing center organization GO:0031023 62 0.044
metaphase plate congression GO:0051310 18 0.044
establishment or maintenance of cell polarity GO:0007163 31 0.043
establishment of spindle orientation GO:0051294 9 0.042
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.042
metaphase anaphase transition of cell cycle GO:0044784 21 0.041
neuroblast proliferation GO:0007405 4 0.040
vesicle mediated transport GO:0016192 371 0.040
reproductive system development GO:0061458 56 0.040
Worm
negative regulation of mitosis GO:0045839 24 0.039
regulation of microtubule based process GO:0032886 74 0.039
regulation of protein processing GO:0070613 150 0.039
modification dependent macromolecule catabolic process GO:0043632 212 0.038
protein polymerization GO:0051258 71 0.038
regulation of mitotic cell cycle phase transition GO:1901990 118 0.037
ribonucleotide catabolic process GO:0009261 405 0.037
positive regulation of cellular catabolic process GO:0031331 284 0.037
mitotic cell cycle checkpoint GO:0007093 68 0.037
regulation of cell differentiation GO:0045595 393 0.037
regulation of sister chromatid segregation GO:0033045 27 0.036
centrosome organization GO:0051297 58 0.036
endomembrane system organization GO:0010256 196 0.035
post embryonic development GO:0009791 2 0.035
regulation of mitotic cell cycle GO:0007346 189 0.035
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.034
negative regulation of cellular protein catabolic process GO:1903363 38 0.033
blastocyst development GO:0001824 3 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.032
positive regulation of phosphorylation GO:0042327 394 0.032
cell cycle phase transition GO:0044770 173 0.032
intrinsic apoptotic signaling pathway GO:0097193 127 0.032
small gtpase mediated signal transduction GO:0007264 78 0.031
cellular protein catabolic process GO:0044257 261 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.030
sister chromatid cohesion GO:0007062 24 0.030
regulation of chromosome organization GO:0033044 103 0.030
centromeric sister chromatid cohesion GO:0070601 3 0.029
mitotic centrosome separation GO:0007100 1 0.029
maintenance of location GO:0051235 112 0.029
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
centrosome duplication GO:0051298 28 0.027
regulation of cellular component movement GO:0051270 334 0.027
Worm
regulation of cellular ketone metabolic process GO:0010565 50 0.027
dna packaging GO:0006323 77 0.027
protein processing GO:0016485 226 0.027
protein complex disassembly GO:0043241 52 0.027
protein catabolic process GO:0030163 325 0.027
positive regulation of cell death GO:0010942 263 0.027
regulation of cellular response to stress GO:0080135 244 0.027
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.026
establishment of organelle localization GO:0051656 59 0.026
nucleoside monophosphate catabolic process GO:0009125 159 0.026
positive regulation of protein phosphorylation GO:0001934 313 0.025
reproduction GO:0000003 63 0.025
Worm
negative regulation of protein metabolic process GO:0051248 391 0.025
positive regulation of mitotic sister chromatid separation GO:1901970 6 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
regulation of nuclear division GO:0051783 65 0.024
protein maturation GO:0051604 233 0.023
cell cycle checkpoint GO:0000075 117 0.023
ribonucleoside monophosphate catabolic process GO:0009158 158 0.022
positive regulation of proteolysis GO:0045862 142 0.022
oogenesis GO:0048477 2 0.022
dna ligation involved in dna repair GO:0051103 4 0.022
ribosome assembly GO:0042255 9 0.021
regulation of response to dna damage stimulus GO:2001020 94 0.021
positive regulation of wnt signaling pathway GO:0030177 54 0.021
ras protein signal transduction GO:0007265 73 0.021
regulation of kinase activity GO:0043549 314 0.021
nervous system development GO:0007399 293 0.020
positive regulation of mitosis GO:0045840 25 0.020
regeneration GO:0031099 4 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
regulation of spindle organization GO:0090224 10 0.020
negative regulation of catabolic process GO:0009895 104 0.020
negative regulation of cell death GO:0060548 345 0.020
histone modification GO:0016570 251 0.019
epithelium development GO:0060429 227 0.019
regulation of transferase activity GO:0051338 355 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
endocytosis GO:0006897 159 0.018
protein autophosphorylation GO:0046777 123 0.018
regulation of meiosis GO:0040020 3 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
Worm
purine ribonucleoside metabolic process GO:0046128 437 0.018
secretion GO:0046903 254 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
protein dna complex assembly GO:0065004 64 0.017
kinetochore organization GO:0051383 8 0.017
regulation of cellular protein catabolic process GO:1903362 96 0.016
developmental process involved in reproduction GO:0003006 66 0.016
Worm
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
neurogenesis GO:0022008 169 0.016
negative regulation of cellular catabolic process GO:0031330 83 0.016
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.016
centrosome separation GO:0051299 3 0.016
male meiosis GO:0007140 1 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
positive regulation of transferase activity GO:0051347 227 0.016
negative regulation of cell cycle phase transition GO:1901988 89 0.015
regulation of ras protein signal transduction GO:0046578 155 0.015
negative regulation of protein catabolic process GO:0042177 59 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
positive regulation of cell division GO:0051781 59 0.015
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.015
Worm
negative regulation of protein processing GO:0010955 142 0.015
single organism membrane organization GO:0044802 268 0.014
macromolecular complex disassembly GO:0032984 60 0.014
single organism reproductive process GO:0044702 98 0.014
Worm
protein localization to chromosome GO:0034502 30 0.014
regulation of protein complex assembly GO:0043254 147 0.013
blood vessel morphogenesis GO:0048514 162 0.013
stem cell division GO:0017145 2 0.013
positive regulation of attachment of spindle microtubules to kinetochore GO:0051987 2 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
organ morphogenesis GO:0009887 147 0.013
Worm
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
regulation of protein kinase activity GO:0045859 289 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
microtubule anchoring GO:0034453 24 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
negative regulation of cytoskeleton organization GO:0051494 45 0.013
positive regulation of organelle organization GO:0010638 195 0.012
positive regulation of protein transport GO:0051222 135 0.012
tissue regeneration GO:0042246 3 0.012
female gamete generation GO:0007292 2 0.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.012
response to radiation GO:0009314 151 0.012
spindle checkpoint GO:0031577 26 0.012
negative regulation of proteolysis GO:0045861 132 0.012
cellular ketone metabolic process GO:0042180 80 0.011
regulation of locomotion GO:0040012 329 0.011
Worm
ribonucleoside catabolic process GO:0042454 406 0.011
nucleotide catabolic process GO:0009166 408 0.011
growth GO:0040007 202 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.011
angiogenesis GO:0001525 147 0.011
mitotic spindle elongation GO:0000022 4 0.011
positive regulation of developmental process GO:0051094 314 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.011
positive regulation of cell cycle GO:0045787 140 0.010
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
regulation of cellular amino acid metabolic process GO:0006521 6 0.010
brain development GO:0007420 97 0.010
multicellular organismal aging GO:0010259 3 0.010
signal transduction by phosphorylation GO:0023014 297 0.010
cytokinesis completion of separation GO:0007109 3 0.010
mapk cascade GO:0000165 288 0.010
immune system development GO:0002520 195 0.010

NDC80 disease predictions

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 41 0.099
congenital nervous system abnormality DOID:2490 21 0.099
disease of cellular proliferation DOID:14566 174 0.026
cancer DOID:162 167 0.020