Homo sapiens

133 known processes

CST3

cystatin C

(Aliases: MGC117328,ARMD11)

CST3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.227
Human
tissue homeostasis GO:0001894 63 0.143
Human
protein processing GO:0016485 226 0.137
sensory perception of bitter taste GO:0050913 28 0.131
Human
positive regulation of cellular component organization GO:0051130 376 0.128
response to external biotic stimulus GO:0043207 261 0.112
cell adhesion GO:0007155 325 0.110
anatomical structure homeostasis GO:0060249 100 0.110
Human
cellular macromolecule catabolic process GO:0044265 380 0.103
response to biotic stimulus GO:0009607 276 0.100
multicellular organismal aging GO:0010259 3 0.098
cellular amino acid metabolic process GO:0006520 116 0.096
positive regulation of cellular amine metabolic process GO:0033240 7 0.090
negative regulation of cell proliferation GO:0008285 228 0.085
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.082
regulation of cell motility GO:2000145 299 0.080
positive regulation of kinase activity GO:0033674 204 0.078
positive regulation of phosphorylation GO:0042327 394 0.075
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
response to other organism GO:0051707 261 0.070
determination of adult lifespan GO:0008340 2 0.068
system process GO:0003008 349 0.066
Human
innate immune response GO:0045087 178 0.064
post embryonic development GO:0009791 2 0.064
negative regulation of cellular protein metabolic process GO:0032269 353 0.064
biological adhesion GO:0022610 331 0.063
detection of chemical stimulus GO:0009593 55 0.062
Human
amine metabolic process GO:0009308 44 0.058
negative regulation of multicellular organismal process GO:0051241 317 0.058
signal transduction by phosphorylation GO:0023014 297 0.058
neurological system process GO:0050877 163 0.056
Human
sensory perception of taste GO:0050909 36 0.053
Human
negative regulation of hydrolase activity GO:0051346 182 0.053
regulation of cellular amino acid metabolic process GO:0006521 6 0.052
multicellular organismal homeostasis GO:0048871 67 0.052
Human
vesicle mediated transport GO:0016192 371 0.052
epithelium development GO:0060429 227 0.051
Rat
antigen processing and presentation GO:0019882 33 0.050
positive regulation of developmental process GO:0051094 314 0.050
response to wounding GO:0009611 168 0.049
Rat
protein catabolic process GO:0030163 325 0.049
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.048
chemical homeostasis GO:0048878 306 0.048
metal ion transport GO:0030001 272 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.048
regulation of cell differentiation GO:0045595 393 0.048
regulation of cellular ketone metabolic process GO:0010565 50 0.045
regulation of mapk cascade GO:0043408 262 0.042
negative regulation of catalytic activity GO:0043086 335 0.042
sensory perception of chemical stimulus GO:0007606 38 0.042
Human
negative regulation of cell death GO:0060548 345 0.042
Rat
cellular amine metabolic process GO:0044106 41 0.041
cellular protein catabolic process GO:0044257 261 0.041
regulation of cellular amine metabolic process GO:0033238 11 0.040
negative regulation of apoptotic process GO:0043066 316 0.040
negative regulation of dendritic cell differentiation GO:2001199 2 0.040
regulation of cell migration GO:0030334 289 0.040
immune system development GO:0002520 195 0.040
leukocyte differentiation GO:0002521 98 0.040
cellular ketone metabolic process GO:0042180 80 0.039
negative regulation of cellular catabolic process GO:0031330 83 0.039
lipid metabolic process GO:0006629 381 0.038
negative regulation of proteolysis GO:0045861 132 0.038
negative regulation of protein metabolic process GO:0051248 391 0.037
gtp metabolic process GO:0046039 239 0.037
cellular protein complex assembly GO:0043623 188 0.036
single organism membrane organization GO:0044802 268 0.036
antigen processing and presentation of peptide antigen GO:0048002 18 0.036
regulation of transferase activity GO:0051338 355 0.036
defense response GO:0006952 315 0.035
regulation of protein processing GO:0070613 150 0.033
regulation of proteolysis GO:0030162 293 0.033
cellular amide metabolic process GO:0043603 69 0.032
regeneration GO:0031099 4 0.032
immune response GO:0006955 307 0.032
hemopoiesis GO:0030097 180 0.032
positive regulation of t cell tolerance induction GO:0002666 2 0.032
thiamine transport GO:0015888 3 0.031
cell development GO:0048468 328 0.031
Rat
actin filament based process GO:0030029 224 0.031
positive regulation of transferase activity GO:0051347 227 0.031
central nervous system development GO:0007417 123 0.030
Rat
positive regulation of cell differentiation GO:0045597 211 0.030
regulation of lipid metabolic process GO:0019216 96 0.030
cytoplasmic transport GO:0016482 379 0.030
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.029
glycerophospholipid metabolic process GO:0006650 84 0.029
carbohydrate derivative biosynthetic process GO:1901137 207 0.028
chemical homeostasis within a tissue GO:0048875 3 0.028
positive regulation of protein phosphorylation GO:0001934 313 0.028
endocytosis GO:0006897 159 0.027
regulation of kinase activity GO:0043549 314 0.027
mapk cascade GO:0000165 288 0.027
regulation of protein maturation GO:1903317 150 0.027
cytokine production GO:0001816 247 0.027
positive regulation of programmed cell death GO:0043068 249 0.026
positive regulation of transport GO:0051050 336 0.026
membrane organization GO:0061024 292 0.026
negative regulation of catabolic process GO:0009895 104 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
female gamete generation GO:0007292 2 0.025
neurogenesis GO:0022008 169 0.025
thiamine transmembrane transport GO:0071934 2 0.025
positive regulation of cell motility GO:2000147 177 0.025
regulation of gtp catabolic process GO:0033124 180 0.025
regulation of nucleotide metabolic process GO:0006140 269 0.024
positive regulation of protein kinase activity GO:0045860 190 0.024
regulation of vesicle mediated transport GO:0060627 130 0.024
positive regulation of catabolic process GO:0009896 310 0.023
epithelial cell differentiation GO:0030855 141 0.023
Rat
ribonucleotide catabolic process GO:0009261 405 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
response to bacterium GO:0009617 144 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
response to cytokine GO:0034097 232 0.022
antigen processing and presentation via mhc class ib GO:0002475 3 0.022
negative regulation of peptidase activity GO:0010466 91 0.022
regulation of leukocyte differentiation GO:1902105 61 0.022
autophagy GO:0006914 88 0.022
positive regulation of cytokine production GO:0001819 167 0.022
regulation of ion transport GO:0043269 189 0.021
circulatory system development GO:0072359 262 0.021
positive regulation of organelle organization GO:0010638 195 0.021
positive regulation of cell migration GO:0030335 172 0.021
camp biosynthetic process GO:0006171 47 0.021
endothelial cell migration GO:0043542 86 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
regulation of epithelial cell proliferation GO:0050678 113 0.020
regulation of protein kinase activity GO:0045859 289 0.020
wound healing GO:0042060 115 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
cellular macromolecular complex assembly GO:0034622 324 0.019
cellular response to external stimulus GO:0071496 111 0.019
tissue regeneration GO:0042246 3 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
response to fungus GO:0009620 4 0.019
plasma membrane fusion GO:0045026 2 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
protein maturation GO:0051604 233 0.019
cation transport GO:0006812 331 0.019
regulation of cellular response to stress GO:0080135 244 0.019
cell morphogenesis GO:0000902 296 0.019
negative regulation of cell migration GO:0030336 102 0.019
kidney development GO:0001822 53 0.019
apoptotic signaling pathway GO:0097190 268 0.019
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.018
leukocyte proliferation GO:0070661 74 0.018
leukocyte activation GO:0045321 164 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
Rat
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
organic hydroxy compound transport GO:0015850 63 0.018
ras protein signal transduction GO:0007265 73 0.017
negative regulation of developmental process GO:0051093 247 0.017
cellular component morphogenesis GO:0032989 314 0.017
detection of chemical stimulus involved in sensory perception of taste GO:0050912 31 0.017
Human
regulation of cellular component biogenesis GO:0044087 281 0.017
prostate gland development GO:0030850 3 0.017
t cell proliferation GO:0042098 45 0.017
cell activation GO:0001775 213 0.017
Rat
lipid biosynthetic process GO:0008610 177 0.017
lipid localization GO:0010876 106 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
ameboidal type cell migration GO:0001667 135 0.017
cellular response to thyroid hormone stimulus GO:0097067 9 0.017
locomotory behavior GO:0007626 1 0.017
regulation of cellular component movement GO:0051270 334 0.017
single organism reproductive process GO:0044702 98 0.017
Rat
positive regulation of cell death GO:0010942 263 0.017
peptidyl lysine modification GO:0018205 144 0.017
embryo development GO:0009790 123 0.016
organelle assembly GO:0070925 176 0.016
positive regulation of map kinase activity GO:0043406 80 0.016
regulation of blood vessel remodeling GO:0060312 2 0.016
myeloid cell differentiation GO:0030099 117 0.016
regulation of cell development GO:0060284 161 0.016
regulation of protein catabolic process GO:0042176 155 0.016
glycerolipid biosynthetic process GO:0045017 51 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.016
phospholipid metabolic process GO:0006644 99 0.016
head development GO:0060322 108 0.016
Rat
circulatory system process GO:0003013 113 0.016
nervous system development GO:0007399 293 0.016
Rat
regulation of lymphocyte activation GO:0051249 103 0.015
regulation of exocytosis GO:0017157 46 0.015
heart process GO:0003015 62 0.015
regulation of peptidase activity GO:0052547 180 0.015
detection of stimulus involved in sensory perception GO:0050906 43 0.015
Human
positive regulation of epithelial cell proliferation GO:0050679 65 0.015
camp metabolic process GO:0046058 61 0.015
detection of biotic stimulus GO:0009595 21 0.015
nucleoside catabolic process GO:0009164 408 0.015
t cell activation GO:0042110 99 0.015
vacuole organization GO:0007033 44 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
segmentation GO:0035282 4 0.015
membrane protein proteolysis GO:0033619 38 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
regulation of tolerance induction GO:0002643 4 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
ossification GO:0001503 121 0.014
rho protein signal transduction GO:0007266 26 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
memory GO:0007613 3 0.014
response to starvation GO:0042594 59 0.014
regulation of actin filament based process GO:0032970 141 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
cell projection organization GO:0030030 252 0.014
oxidation reduction process GO:0055114 396 0.014
positive regulation of locomotion GO:0040017 186 0.014
growth GO:0040007 202 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
cellular response to nutrient levels GO:0031669 69 0.014
response to organic cyclic compound GO:0014070 204 0.014
Rat
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
neuromuscular junction development GO:0007528 3 0.014
cellular lipid metabolic process GO:0044255 303 0.013
azole transport GO:0045117 4 0.013
t cell tolerance induction GO:0002517 4 0.013
embryonic hemopoiesis GO:0035162 4 0.013
positive regulation of immune system process GO:0002684 283 0.013
regulation of hormone levels GO:0010817 125 0.013
inner ear morphogenesis GO:0042472 4 0.013
single organism cellular localization GO:1902580 332 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.013
wnt signaling pathway GO:0016055 156 0.013
regulation of defense response GO:0031347 154 0.013
lymphocyte activation GO:0046649 133 0.013
muscle cell cellular homeostasis GO:0046716 3 0.013
cell growth GO:0016049 160 0.013
response to axon injury GO:0048678 1 0.013
Rat
lymphocyte proliferation GO:0046651 70 0.013
lung alveolus development GO:0048286 4 0.013
negative regulation of trophoblast cell migration GO:1901164 3 0.013
response to radiation GO:0009314 151 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.012
regulation of secretion GO:0051046 194 0.012
actin mediated cell contraction GO:0070252 12 0.012
interleukin 12 production GO:0032615 15 0.012
regulation of cytokine production GO:0001817 232 0.012
peptide metabolic process GO:0006518 51 0.012
epithelial cell migration GO:0010631 119 0.012
brain development GO:0007420 97 0.012
Rat
regulation of blood pressure GO:0008217 30 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
regulation of neuron differentiation GO:0045664 70 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
reproductive process GO:0022414 106 0.012
Rat
blastocyst development GO:0001824 3 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
regulation of locomotion GO:0040012 329 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
negative regulation of dna catabolic process GO:1903625 2 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
positive regulation of cytoskeleton organization GO:0051495 83 0.012
eye development GO:0001654 42 0.012
Rat
glycerophospholipid biosynthetic process GO:0046474 40 0.012
positive regulation of ras gtpase activity GO:0032320 117 0.012
negative regulation of transferase activity GO:0051348 124 0.012
positive regulation of leukocyte activation GO:0002696 80 0.012
cell chemotaxis GO:0060326 112 0.012
regulation of cytoskeleton organization GO:0051493 177 0.011
negative regulation of metalloenzyme activity GO:0048553 1 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
blood circulation GO:0008015 113 0.011
response to hormone GO:0009725 175 0.011
Rat
regulation of intracellular transport GO:0032386 195 0.011
cholesterol transport GO:0030301 39 0.011
regulation of angiotensin levels in blood GO:0002002 3 0.011
regulation of lymphocyte proliferation GO:0050670 64 0.011
epithelium migration GO:0090132 119 0.011
regulation of gtpase activity GO:0043087 180 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
regulation of rubidium ion transport GO:2000680 3 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
surfactant homeostasis GO:0043129 3 0.011
regulation of immune effector process GO:0002697 91 0.011
leukocyte mediated cytotoxicity GO:0001909 27 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 28 0.011
Human
regulation of endocytosis GO:0030100 72 0.011
regulation of lymphocyte mediated immunity GO:0002706 33 0.011
protein localization to organelle GO:0033365 280 0.011
metencephalon development GO:0022037 2 0.011
regulation of rho gtpase activity GO:0032319 66 0.011
positive regulation of t cell activation GO:0050870 54 0.011
nucleotide catabolic process GO:0009166 408 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
spermatid differentiation GO:0048515 4 0.011
protein localization to membrane GO:0072657 160 0.011
cellular homeostasis GO:0019725 196 0.011
lipid homeostasis GO:0055088 39 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
heart contraction GO:0060047 62 0.011
response to alcohol GO:0097305 64 0.011
Rat
regulation of growth GO:0040008 165 0.011
transmission of nerve impulse GO:0019226 11 0.011
phosphatidylinositol metabolic process GO:0046488 53 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
maintenance of location GO:0051235 112 0.010
cellular modified amino acid metabolic process GO:0006575 64 0.010
oogenesis GO:0048477 2 0.010
regulation of camp metabolic process GO:0030814 52 0.010
protein stabilization GO:0050821 64 0.010
activation of protein kinase activity GO:0032147 90 0.010
nucleoside phosphate biosynthetic process GO:1901293 109 0.010
positive regulation of endocytosis GO:0045807 42 0.010
neuron projection development GO:0031175 106 0.010
peripheral nervous system development GO:0007422 2 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
regulation of cell cycle process GO:0010564 266 0.010
muscle contraction GO:0006936 73 0.010
necrotic cell death GO:0070265 21 0.010
regulation of leukocyte activation GO:0002694 115 0.010
generation of precursor metabolites and energy GO:0006091 68 0.010
blastoderm segmentation GO:0007350 2 0.010

CST3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.645
inherited metabolic disorder DOID:655 242 0.325
lipid storage disease DOID:9455 28 0.164
lysosomal storage disease DOID:3211 47 0.164
immune system disease DOID:2914 155 0.048
hematopoietic system disease DOID:74 100 0.030
central nervous system disease DOID:331 186 0.029
neurodegenerative disease DOID:1289 102 0.029
nervous system disease DOID:863 431 0.029
neuronal ceroid lipofuscinosis DOID:14503 11 0.017
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
retinal disease DOID:5679 118 0.006
retinal degeneration DOID:8466 89 0.005
acquired metabolic disease DOID:0060158 58 0.003
macular degeneration DOID:4448 20 0.003
amyloidosis DOID:9120 10 0.002
degeneration of macula and posterior pole DOID:2007 17 0.002
age related macular degeneration DOID:10871 17 0.001
cerebral amyloid angiopathy DOID:9246 3 0.000