Homo sapiens

27 known processes

USP6

ubiquitin specific peptidase 6 (Tre-2 oncogene)

(Aliases: USP6-short,TRE2,Tre-2,TRE17,HRP1)

USP6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein deubiquitination GO:0016579 79 0.527
protein modification by small protein removal GO:0070646 92 0.446
regulation of canonical wnt signaling pathway GO:0060828 88 0.307
negative regulation of wnt signaling pathway GO:0030178 69 0.286
canonical wnt signaling pathway GO:0060070 116 0.268
glial cell migration GO:0008347 4 0.239
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.173
regulation of wnt signaling pathway GO:0030111 123 0.159
wnt signaling pathway GO:0016055 156 0.137
histone modification GO:0016570 251 0.108
biological adhesion GO:0022610 331 0.107
chromatin organization GO:0006325 351 0.071
covalent chromatin modification GO:0016569 254 0.067
cell morphogenesis GO:0000902 296 0.066
nucleoside catabolic process GO:0009164 408 0.065
nervous system development GO:0007399 293 0.061
cell adhesion GO:0007155 325 0.058
chromatin modification GO:0016568 298 0.058
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.056
glycosyl compound catabolic process GO:1901658 413 0.055
post embryonic development GO:0009791 2 0.054
single organismal cell cell adhesion GO:0016337 148 0.051
purine ribonucleotide catabolic process GO:0009154 404 0.050
coagulation GO:0050817 78 0.050
regulation of cellular amino acid metabolic process GO:0006521 6 0.049
amine metabolic process GO:0009308 44 0.049
regulation of cellular amine metabolic process GO:0033238 11 0.048
purine nucleoside triphosphate metabolic process GO:0009144 412 0.046
multicellular organismal aging GO:0010259 3 0.046
determination of adult lifespan GO:0008340 2 0.046
regulation of cellular ketone metabolic process GO:0010565 50 0.045
nucleoside phosphate catabolic process GO:1901292 412 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
blood coagulation GO:0007596 76 0.044
purine ribonucleoside metabolic process GO:0046128 437 0.044
single organism cell adhesion GO:0098602 179 0.043
cellular amino acid metabolic process GO:0006520 116 0.042
organophosphate catabolic process GO:0046434 430 0.042
nucleoside triphosphate catabolic process GO:0009143 394 0.042
hemostasis GO:0007599 76 0.042
regulation of growth GO:0040008 165 0.041
system process GO:0003008 349 0.040
locomotory behavior GO:0007626 1 0.040
oogenesis GO:0048477 2 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
regulation of purine nucleotide metabolic process GO:1900542 264 0.038
histone deubiquitination GO:0016578 16 0.038
cell development GO:0048468 328 0.037
organ morphogenesis GO:0009887 147 0.036
regulation of cell differentiation GO:0045595 393 0.036
regulation of cell growth GO:0001558 135 0.035
regulation of body fluid levels GO:0050878 99 0.035
neurogenesis GO:0022008 169 0.035
cellular component morphogenesis GO:0032989 314 0.035
protein catabolic process GO:0030163 325 0.034
lipid metabolic process GO:0006629 381 0.034
generation of neurons GO:0048699 152 0.033
segmentation GO:0035282 4 0.033
cell growth GO:0016049 160 0.032
platelet activation GO:0030168 44 0.032
dephosphorylation GO:0016311 209 0.032
actin filament based process GO:0030029 224 0.032
mitotic cell cycle GO:0000278 326 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.031
transmembrane transport GO:0055085 399 0.031
rho protein signal transduction GO:0007266 26 0.031
regulation of cell cycle GO:0051726 393 0.031
neuron projection development GO:0031175 106 0.030
growth GO:0040007 202 0.030
circulatory system development GO:0072359 262 0.030
tissue morphogenesis GO:0048729 96 0.030
cell activation GO:0001775 213 0.030
cell projection morphogenesis GO:0048858 129 0.030
positive regulation of transport GO:0051050 336 0.029
chemical homeostasis GO:0048878 306 0.029
cell part morphogenesis GO:0032990 137 0.029
cellular ketone metabolic process GO:0042180 80 0.029
cardiovascular system development GO:0072358 262 0.028
vesicle mediated transport GO:0016192 371 0.028
atp catabolic process GO:0006200 157 0.028
ribonucleoside monophosphate metabolic process GO:0009161 187 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
ras protein signal transduction GO:0007265 73 0.028
regulation of kinase activity GO:0043549 314 0.027
cellular lipid metabolic process GO:0044255 303 0.027
metal ion transport GO:0030001 272 0.027
cytoplasmic transport GO:0016482 379 0.027
positive regulation of catabolic process GO:0009896 310 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.027
response to wounding GO:0009611 168 0.026
female gamete generation GO:0007292 2 0.026
neuromuscular junction development GO:0007528 3 0.026
memory GO:0007613 3 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
hindbrain development GO:0030902 3 0.026
actin filament based movement GO:0030048 17 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
ion transmembrane transport GO:0034220 338 0.025
negative regulation of catalytic activity GO:0043086 335 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
guanosine containing compound catabolic process GO:1901069 239 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
protein ubiquitination GO:0016567 314 0.024
nitrogen compound transport GO:0071705 191 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
single organism cellular localization GO:1902580 332 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
homotypic cell cell adhesion GO:0034109 47 0.023
negative regulation of cell growth GO:0030308 83 0.022
heart morphogenesis GO:0003007 48 0.022
cellular protein catabolic process GO:0044257 261 0.022
regulation of cellular response to stress GO:0080135 244 0.022
blastoderm segmentation GO:0007350 2 0.022
microtubule based process GO:0007017 210 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
anterior posterior axis specification GO:0009948 2 0.022
cardiac muscle tissue development GO:0048738 39 0.021
nucleoside monophosphate catabolic process GO:0009125 159 0.021
oocyte development GO:0048599 1 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
cellular protein complex assembly GO:0043623 188 0.021
regulation of transferase activity GO:0051338 355 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
oocyte differentiation GO:0009994 2 0.021
cardiac ventricle morphogenesis GO:0003208 20 0.021
platelet aggregation GO:0070527 32 0.021
protein autophosphorylation GO:0046777 123 0.021
negative regulation of cellular component organization GO:0051129 235 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
regeneration GO:0031099 4 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
proteasomal protein catabolic process GO:0010498 176 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
guanosine containing compound metabolic process GO:1901068 244 0.019
photoreceptor cell differentiation GO:0046530 2 0.019
regulation of mapk cascade GO:0043408 262 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
neuron development GO:0048666 113 0.019
regulation of proteolysis GO:0030162 293 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
heart development GO:0007507 95 0.019
cellular homeostasis GO:0019725 196 0.019
metencephalon development GO:0022037 2 0.019
regulation of synaptic plasticity GO:0048167 3 0.018
single organism membrane organization GO:0044802 268 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
wound healing GO:0042060 115 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
negative regulation of protein modification process GO:0031400 200 0.018
cation transmembrane transport GO:0098655 238 0.018
regulation of vesicle mediated transport GO:0060627 130 0.018
neuroblast proliferation GO:0007405 4 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
cellular amine metabolic process GO:0044106 41 0.018
regulation of intracellular transport GO:0032386 195 0.018
cellular cation homeostasis GO:0030003 163 0.018
dna repair GO:0006281 198 0.018
peripheral nervous system development GO:0007422 2 0.018
maintenance of location GO:0051235 112 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
cell morphogenesis involved in differentiation GO:0000904 144 0.018
actin mediated cell contraction GO:0070252 12 0.017
spermatid differentiation GO:0048515 4 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
carbohydrate metabolic process GO:0005975 207 0.017
defense response GO:0006952 315 0.017
cardiac muscle cell contraction GO:0086003 4 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
regulation of multi organism process GO:0043900 157 0.017
endosomal transport GO:0016197 129 0.017
tripartite regional subdivision GO:0007351 2 0.017
gtp catabolic process GO:0006184 237 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
muscle tissue development GO:0060537 62 0.017
intracellular protein transport GO:0006886 270 0.017
adult locomotory behavior GO:0008344 1 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
regulation of protein serine threonine kinase activity GO:0071900 179 0.016
calcium ion transport GO:0006816 147 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
positive regulation of organelle organization GO:0010638 195 0.016
neurological system process GO:0050877 163 0.016
protein maturation GO:0051604 233 0.016
multi organism cellular process GO:0044764 156 0.016
cell projection organization GO:0030030 252 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
endocytosis GO:0006897 159 0.016
cell fate determination GO:0001709 3 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
spermatid development GO:0007286 4 0.016
nerve development GO:0021675 4 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
epithelium development GO:0060429 227 0.016
innate immune response GO:0045087 178 0.016
regulation of actin filament based process GO:0032970 141 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
mapk cascade GO:0000165 288 0.015
negative regulation of developmental process GO:0051093 247 0.015
cardiac chamber development GO:0003205 30 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
striated muscle tissue development GO:0014706 59 0.015
compound eye development GO:0048749 1 0.015
regulation of cell migration GO:0030334 289 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
protein targeting GO:0006605 187 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
lipid biosynthetic process GO:0008610 177 0.015
inner ear morphogenesis GO:0042472 4 0.015
regulation of protein kinase activity GO:0045859 289 0.015
regulation of ion transport GO:0043269 189 0.015
immune system development GO:0002520 195 0.015
regulation of protein transport GO:0051223 213 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
positive regulation of kinase activity GO:0033674 204 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.015
positive regulation of cell death GO:0010942 263 0.015
regulation of cytokine production GO:0001817 232 0.015
cellular metal ion homeostasis GO:0006875 146 0.015
metal ion homeostasis GO:0055065 169 0.015
rhythmic behavior GO:0007622 2 0.015
neuron differentiation GO:0030182 138 0.015
response to abiotic stimulus GO:0009628 336 0.015
positive regulation of transferase activity GO:0051347 227 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
immune response GO:0006955 307 0.014
mating GO:0007618 1 0.014
cranial nerve development GO:0021545 4 0.014
secretion by cell GO:0032940 226 0.014
negative regulation of organelle organization GO:0010639 126 0.014
cardiac chamber morphogenesis GO:0003206 26 0.014
cytokine production GO:0001816 247 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
circadian behavior GO:0048512 2 0.014
response to fungus GO:0009620 4 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
muscle tissue morphogenesis GO:0060415 19 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
cerebellum development GO:0021549 2 0.014
regulation of protein processing GO:0070613 150 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
sequestering of metal ion GO:0051238 24 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
negative regulation of cell death GO:0060548 345 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
regulation of peptidase activity GO:0052547 180 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.014
response to oxygen containing compound GO:1901700 369 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.013
interspecies interaction between organisms GO:0044419 156 0.013
mrna metabolic process GO:0016071 175 0.013
regulation of cell cycle process GO:0010564 266 0.013
stem cell division GO:0017145 2 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
regulation of protein localization GO:0032880 296 0.013
positive regulation of developmental process GO:0051094 314 0.013
detection of stimulus GO:0051606 85 0.013
regulation of cell motility GO:2000145 299 0.013
t cell differentiation in thymus GO:0033077 4 0.013
taxis GO:0042330 157 0.013
cellular chemical homeostasis GO:0055082 180 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
protein localization to organelle GO:0033365 280 0.013
viral process GO:0016032 146 0.013
sequestering of calcium ion GO:0051208 17 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
muscle structure development GO:0061061 98 0.013
secretion GO:0046903 254 0.013
regulation of viral process GO:0050792 103 0.013
rna interference GO:0016246 4 0.013
protein localization to membrane GO:0072657 160 0.013
neuron projection morphogenesis GO:0048812 50 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
peptidyl serine modification GO:0018209 106 0.013
limbic system development GO:0021761 3 0.013
response to external biotic stimulus GO:0043207 261 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
protein processing GO:0016485 226 0.013
cellular divalent inorganic cation homeostasis GO:0072503 128 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.012
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
visual behavior GO:0007632 2 0.012
organ formation GO:0048645 3 0.012
negative regulation of protein maturation GO:1903318 142 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
glycoprotein metabolic process GO:0009100 110 0.012
protein oligomerization GO:0051259 173 0.012
regulation of cell division GO:0051302 116 0.012
hemopoiesis GO:0030097 180 0.012
associative learning GO:0008306 1 0.012
specification of organ identity GO:0010092 3 0.012
post embryonic organ development GO:0048569 1 0.012
muscle system process GO:0003012 81 0.012
negative regulation of protein processing GO:0010955 142 0.012
positive regulation of locomotion GO:0040017 186 0.012
nuclear transport GO:0051169 179 0.012
regulation of dna metabolic process GO:0051052 153 0.012
regulation of phosphatase activity GO:0010921 81 0.012
viral life cycle GO:0019058 132 0.012
response to other organism GO:0051707 261 0.012
regulation of cell development GO:0060284 161 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
glycerolipid metabolic process GO:0046486 107 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
oxidation reduction process GO:0055114 396 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
cardiac ventricle development GO:0003231 23 0.012
striated muscle contraction GO:0006941 52 0.012
stress activated protein kinase signaling cascade GO:0031098 94 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
small molecule biosynthetic process GO:0044283 157 0.012
cell projection assembly GO:0030031 126 0.011
neurotransmitter secretion GO:0007269 4 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
response to cytokine GO:0034097 232 0.011
regulation of protein maturation GO:1903317 150 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
cdc42 protein signal transduction GO:0032488 4 0.011
membrane organization GO:0061024 292 0.011
endomembrane system organization GO:0010256 196 0.011
mitotic nuclear division GO:0007067 119 0.011
negative regulation of cell cycle GO:0045786 193 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
regulation of protein catabolic process GO:0042176 155 0.011
negative regulation of transport GO:0051051 176 0.011
regulation of locomotion GO:0040012 329 0.011
long term memory GO:0007616 2 0.011
response to activity GO:0014823 0 0.011
eye photoreceptor cell differentiation GO:0001754 2 0.011
negative regulation of proteolysis GO:0045861 132 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
thymus development GO:0048538 3 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
fatty acid metabolic process GO:0006631 115 0.011
response to axon injury GO:0048678 1 0.011
cell type specific apoptotic process GO:0097285 125 0.011
defense response to fungus GO:0050832 4 0.011
cardiac muscle tissue morphogenesis GO:0055008 18 0.011
positive regulation of cell migration GO:0030335 172 0.011
meiotic chromosome segregation GO:0045132 4 0.011
response to radiation GO:0009314 151 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
sensory perception of smell GO:0007608 2 0.011
tissue regeneration GO:0042246 3 0.011
jnk cascade GO:0007254 80 0.011
axonogenesis GO:0007409 31 0.011
organic acid biosynthetic process GO:0016053 97 0.011
calcium ion homeostasis GO:0055074 122 0.011
somatic stem cell division GO:0048103 1 0.011
somatic muscle development GO:0007525 1 0.011
regulation of transmembrane transport GO:0034762 139 0.011
tube closure GO:0060606 3 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
regulation of dephosphorylation GO:0035303 96 0.010
small molecule catabolic process GO:0044282 92 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.010
central nervous system development GO:0007417 123 0.010
asymmetric stem cell division GO:0098722 1 0.010
sensory perception GO:0007600 103 0.010
ossification GO:0001503 121 0.010
protein homooligomerization GO:0051260 100 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
mitotic cell cycle process GO:1903047 286 0.010
meiosis i GO:0007127 4 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
regulation of cell adhesion GO:0030155 166 0.010
phospholipid metabolic process GO:0006644 99 0.010
response to biotic stimulus GO:0009607 276 0.010
melanin metabolic process GO:0006582 1 0.010
modification dependent protein catabolic process GO:0019941 209 0.010
anion transport GO:0006820 161 0.010
regulation of secretion by cell GO:1903530 177 0.010
cell substrate adhesion GO:0031589 132 0.010
muscle organ development GO:0007517 56 0.010
response to inorganic substance GO:0010035 127 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
negative regulation of catabolic process GO:0009895 104 0.010
regulation of cellular component movement GO:0051270 334 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.010
ventricular cardiac muscle tissue development GO:0003229 14 0.010
amide transport GO:0042886 76 0.010
positive regulation of protein transport GO:0051222 135 0.010
apoptotic signaling pathway GO:0097190 268 0.010
brain development GO:0007420 97 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
glycosylation GO:0070085 71 0.010
somitogenesis GO:0001756 2 0.010
angiogenesis GO:0001525 147 0.010
regulation of meiosis GO:0040020 3 0.010
heart formation GO:0060914 2 0.010
receptor metabolic process GO:0043112 81 0.010

USP6 disease predictions

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 106 0.158
heart disease DOID:114 68 0.157
myopathy DOID:423 104 0.150
muscular disease DOID:0080000 114 0.150
cardiomyopathy DOID:0050700 50 0.150
intrinsic cardiomyopathy DOID:0060036 50 0.150
musculoskeletal system disease DOID:17 223 0.150
muscle tissue disease DOID:66 113 0.150
hypertrophic cardiomyopathy DOID:11984 21 0.078
sensory system disease DOID:0050155 203 0.025
nervous system disease DOID:863 431 0.025
central nervous system disease DOID:331 186 0.021
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
disease of metabolism DOID:0014667 295 0.018
organ system cancer DOID:0050686 164 0.018
eye and adnexa disease DOID:1492 150 0.017
eye disease DOID:5614 149 0.017
immune system disease DOID:2914 155 0.014
retinal disease DOID:5679 118 0.013
inherited metabolic disorder DOID:655 242 0.013
connective tissue disease DOID:65 109 0.012
neurodegenerative disease DOID:1289 102 0.012
bone disease DOID:0080001 88 0.011
auditory system disease DOID:2742 53 0.011