|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
1.000
|
|
|
|
regulation of heart induction by regulation of canonical wnt signaling pathway
|
GO:0090081 |
1 |
1.000
|
|
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
1.000
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
1.000
|
Human |
|
|
regulation of methylation dependent chromatin silencing
|
GO:0090308 |
3 |
0.999
|
|
|
|
extraocular skeletal muscle development
|
GO:0002074 |
1 |
0.990
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.984
|
|
|
|
negative regulation of posttranscriptional gene silencing
|
GO:0060149 |
3 |
0.972
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.971
|
Human Mouse |
|
|
bmp signaling pathway involved in heart induction
|
GO:0003130 |
3 |
0.937
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.927
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.924
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.919
|
|
|
|
ectodermal cell fate commitment
|
GO:0001712 |
1 |
0.904
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.894
|
|
|
|
endodermal mesodermal cell signaling involved in heart induction
|
GO:0003134 |
3 |
0.885
|
|
|
|
menstrual cycle phase
|
GO:0022601 |
2 |
0.878
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.876
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.875
|
|
|
|
negative regulation of gene silencing by rna
|
GO:0060967 |
3 |
0.874
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.850
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.840
|
Human Mouse |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.838
|
Human |
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.834
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.833
|
|
|
|
regulation of wnt signaling pathway involved in heart development
|
GO:0003307 |
3 |
0.813
|
|
|
|
negative regulation of gene silencing by mirna
|
GO:0060965 |
3 |
0.795
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.789
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.788
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.784
|
Human |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.768
|
Human Zebrafish Mouse |
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.744
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.742
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.731
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.729
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.708
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.706
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.700
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.700
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.692
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.683
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.666
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.655
|
|
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.590
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.535
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.512
|
Human Mouse |
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.509
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.507
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.507
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.476
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.455
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.446
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.440
|
Human Mouse |
|
|
epithelium development
|
GO:0060429 |
227 |
0.434
|
Human Mouse |
|
|
heart induction
|
GO:0003129 |
4 |
0.434
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.415
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.415
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.401
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.400
|
Human |
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.391
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.377
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.371
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.364
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.363
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.347
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.345
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.337
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.332
|
|
|
|
system process
|
GO:0003008 |
349 |
0.332
|
Mouse |
|
|
heart field specification
|
GO:0003128 |
2 |
0.330
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.313
|
Human Zebrafish Mouse Fly |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.304
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.298
|
|
|
|
enteric nervous system development
|
GO:0048484 |
1 |
0.295
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.275
|
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.269
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.268
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.267
|
Human Zebrafish Mouse Fly |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.265
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.256
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.249
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.246
|
Human |
|
|
gland development
|
GO:0048732 |
48 |
0.243
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.242
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.238
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.235
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.234
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.233
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.231
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.229
|
Fly |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.225
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.221
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.220
|
|
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.211
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.210
|
Human |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.208
|
Human Mouse |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.207
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.207
|
Human Mouse |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.207
|
Mouse |
|
|
organ induction
|
GO:0001759 |
4 |
0.205
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.205
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.204
|
Fly |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.201
|
Human |
|
|
soft palate development
|
GO:0060023 |
3 |
0.201
|
|
|
|
embryonic digit morphogenesis
|
GO:0042733 |
6 |
0.196
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.193
|
Human |
|
|
ectoderm development
|
GO:0007398 |
3 |
0.191
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.187
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.186
|
|
|
|
renal vesicle development
|
GO:0072087 |
4 |
0.185
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.180
|
Human Zebrafish Mouse Fly |
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.180
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.178
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.174
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.174
|
Human |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.171
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.171
|
Human Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.170
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.170
|
Fly |
|
|
menstruation
|
GO:0042703 |
1 |
0.167
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.163
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.163
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.160
|
Human |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.159
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.159
|
Human |
|
|
telencephalon development
|
GO:0021537 |
17 |
0.157
|
Mouse |
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.156
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
15 |
0.154
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.154
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.154
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.152
|
Human |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.151
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.150
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.148
|
Human |
|
|
renal vesicle morphogenesis
|
GO:0072077 |
4 |
0.148
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.147
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.143
|
Human |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.142
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
9 |
0.140
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.140
|
Fly |
|
|
connective tissue development
|
GO:0061448 |
39 |
0.136
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.136
|
Human Mouse |
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.134
|
Human Mouse |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.132
|
Human Mouse |
|
|
forebrain dorsal ventral pattern formation
|
GO:0021798 |
1 |
0.131
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.130
|
Human Mouse |
|
|
kidney development
|
GO:0001822 |
53 |
0.129
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.129
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.128
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.127
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.127
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.125
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.124
|
|
|
|
mrna transcription from rna polymerase ii promoter
|
GO:0042789 |
6 |
0.124
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.123
|
Mouse |
|
|
sensory organ development
|
GO:0007423 |
52 |
0.123
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.122
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.122
|
Mouse |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.121
|
Human Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.121
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.120
|
Fly |
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.119
|
Human |
|
|
cell division
|
GO:0051301 |
168 |
0.118
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.118
|
Mouse |
|
|
segmentation
|
GO:0035282 |
4 |
0.118
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.117
|
Mouse |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.115
|
Human |
|
|
embryo development
|
GO:0009790 |
123 |
0.115
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.114
|
Human |
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.111
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.108
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.108
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.108
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.107
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.106
|
Zebrafish Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.106
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.104
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.104
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.104
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.104
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.104
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.103
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.103
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.103
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.102
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.102
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.102
|
Human |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.101
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.100
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.099
|
Zebrafish |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.098
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.098
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.097
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.097
|
Mouse |
|
|
response to hormone
|
GO:0009725 |
175 |
0.096
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.093
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.093
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.093
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.093
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.093
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.092
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.091
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.091
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.090
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.090
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.089
|
Fly |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.089
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.088
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.088
|
Human Mouse |
|
|
glial cell differentiation
|
GO:0010001 |
11 |
0.088
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.087
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.087
|
|
|
|
outer ear morphogenesis
|
GO:0042473 |
2 |
0.087
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.086
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.086
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.086
|
Human |
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.086
|
Human Mouse |
|
|
response to wounding
|
GO:0009611 |
168 |
0.086
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.085
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.084
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.084
|
Human |
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.083
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.083
|
Human Mouse |
|
|
vasculature development
|
GO:0001944 |
181 |
0.083
|
Human |
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.083
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.082
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.082
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.082
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.082
|
Human |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.081
|
Mouse |
|
|
viral life cycle
|
GO:0019058 |
132 |
0.081
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.081
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.080
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.080
|
Human |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.079
|
Human |
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.079
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.078
|
|
|
|
metanephric nephron morphogenesis
|
GO:0072273 |
7 |
0.077
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.077
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.076
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.076
|
Human |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.076
|
Human |
|
|
olfactory lobe development
|
GO:0021988 |
5 |
0.076
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.076
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.075
|
|
|
|
olfactory bulb development
|
GO:0021772 |
5 |
0.074
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.073
|
|
|
|
growth
|
GO:0040007 |
202 |
0.073
|
Human Zebrafish |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.072
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.072
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.071
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.071
|
Human Mouse |
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.071
|
Mouse |
|
|
negative regulation by host of viral transcription
|
GO:0043922 |
12 |
0.071
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.070
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.070
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.070
|
Mouse |
|
|
immune system development
|
GO:0002520 |
195 |
0.070
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.070
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.070
|
|
|
|
pancreatic a cell differentiation
|
GO:0003310 |
1 |
0.070
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.069
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.069
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.069
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.069
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.069
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.068
|
Human |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.068
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.068
|
|
|
|
regulation of transcription involved in cell fate commitment
|
GO:0060850 |
6 |
0.068
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
6 |
0.068
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.068
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.067
|
|
|
|
limb morphogenesis
|
GO:0035108 |
16 |
0.067
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.067
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.067
|
Zebrafish |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.066
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.066
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.065
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.065
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.065
|
Human |
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.063
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.063
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.063
|
Human Mouse |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.062
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.062
|
Human |
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.062
|
|
|
|
ectoderm formation
|
GO:0001705 |
1 |
0.062
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.061
|
|
|
|
ear morphogenesis
|
GO:0042471 |
7 |
0.061
|
Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.061
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.061
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.061
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.060
|
|
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
26 |
0.059
|
|
|
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.059
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.059
|
|
|
|
metanephric nephron development
|
GO:0072210 |
9 |
0.058
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.058
|
Human |
|
|
modulation of transcription in other organism involved in symbiotic interaction
|
GO:0052312 |
20 |
0.058
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.058
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.058
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.058
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.058
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.057
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.057
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.057
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.056
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.056
|
|
|
|
metanephric renal vesicle morphogenesis
|
GO:0072283 |
4 |
0.056
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.056
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.056
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.055
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.055
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.055
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.055
|
Human |
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.055
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.055
|
|
|
|
developmental induction
|
GO:0031128 |
5 |
0.055
|
Mouse |
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
22 |
0.054
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.054
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
8 |
0.053
|
|
|
|
head development
|
GO:0060322 |
108 |
0.053
|
|
|
|
male gonad development
|
GO:0008584 |
23 |
0.053
|
Human |
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.053
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.053
|
Human |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.053
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.052
|
Human |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.052
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.052
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.052
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.052
|
Zebrafish |
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.051
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.051
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.051
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.051
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.051
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.050
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.050
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.050
|
Human |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.050
|
Fly |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.049
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.049
|
Mouse |
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.049
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.049
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.049
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.048
|
Human |
|
|
modulation by host of symbiont transcription
|
GO:0052472 |
20 |
0.048
|
|
|
|
limb development
|
GO:0060173 |
23 |
0.048
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.048
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
23 |
0.048
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.048
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.048
|
Human |
|
|
epidermis development
|
GO:0008544 |
59 |
0.048
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.048
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.047
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.047
|
Zebrafish Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.047
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.047
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.047
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.047
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.046
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.046
|
Human |
|
|
exocytosis
|
GO:0006887 |
71 |
0.045
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.044
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.044
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.044
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.044
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.044
|
Human |
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.044
|
Human Mouse |
|
|
protein targeting
|
GO:0006605 |
187 |
0.044
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.044
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.043
|
Human Mouse |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.043
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.043
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.043
|
Human |
|
|
positive regulation of cell fate specification
|
GO:0042660 |
2 |
0.043
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.043
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.042
|
|
|
|
ear development
|
GO:0043583 |
14 |
0.042
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.042
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.042
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.042
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.042
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.041
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.041
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.041
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.041
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.041
|
Human |
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.041
|
Human Mouse |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.041
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.041
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.041
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.041
|
Mouse |
|
|
male genitalia development
|
GO:0030539 |
1 |
0.041
|
Mouse |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.041
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.040
|
|
|
|
regulation of acrosome reaction
|
GO:0060046 |
4 |
0.040
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.040
|
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
23 |
0.040
|
|
|
|
memory
|
GO:0007613 |
3 |
0.040
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.040
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.040
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.040
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.040
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.039
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.039
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.039
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.039
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.039
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.039
|
Human |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.039
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.039
|
|
|
|
intracellular estrogen receptor signaling pathway
|
GO:0030520 |
23 |
0.039
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.039
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.039
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.039
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.038
|
Zebrafish |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.038
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.038
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.038
|
Mouse |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.038
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.038
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.037
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.037
|
|
|
|
ventral spinal cord interneuron differentiation
|
GO:0021514 |
1 |
0.037
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.037
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.037
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.037
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.037
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.037
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.037
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.037
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.036
|
Human |
|
|
pancreas development
|
GO:0031016 |
19 |
0.036
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.036
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in heart development
|
GO:1901213 |
6 |
0.036
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.036
|
Mouse |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.035
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.035
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.035
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.035
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.035
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.035
|
Human |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.035
|
Fly |
|
|
hormone secretion
|
GO:0046879 |
65 |
0.034
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.034
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.034
|
Mouse |
|
|
negative regulation of epithelial to mesenchymal transition
|
GO:0010719 |
14 |
0.034
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.034
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.034
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.034
|
Human |
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.034
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.034
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.034
|
Human |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.033
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.033
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.033
|
Human |
|
|
aging
|
GO:0007568 |
66 |
0.033
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.033
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.033
|
Human |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.033
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.033
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.033
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.033
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.033
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.033
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.033
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.033
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.033
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.033
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.033
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.032
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.032
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.032
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.032
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.032
|
Human Mouse |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.032
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.032
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.032
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.032
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.032
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.032
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.031
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.031
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.031
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.031
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.031
|
|
|
|
interaction with symbiont
|
GO:0051702 |
26 |
0.031
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.030
|
|
