Homo sapiens

179 known processes

TNFRSF11A

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

(Aliases: ODFR,OFE,FEO,CD265,PDB2,RANK,OPTB7,TRANCER,LOH18CR1,OSTS)

TNFRSF11A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 80 0.130
cellular amine metabolic process GO:0044106 41 0.129
regulation of cytokine production GO:0001817 232 0.128
Human
response to oxygen containing compound GO:1901700 369 0.121
Human Mouse
cellular response to oxygen containing compound GO:1901701 276 0.116
Human
positive regulation of protein phosphorylation GO:0001934 313 0.110
i kappab kinase nf kappab signaling GO:0007249 166 0.109
Human
regulation of transferase activity GO:0051338 355 0.109
regulation of kinase activity GO:0043549 314 0.107
cellular amino acid metabolic process GO:0006520 116 0.105
mapk cascade GO:0000165 288 0.104
regulation of cellular amino acid metabolic process GO:0006521 6 0.103
positive regulation of phosphorylation GO:0042327 394 0.094
response to lipid GO:0033993 206 0.092
Human Mouse
response to other organism GO:0051707 261 0.092
Human Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.092
Human
cytokine production GO:0001816 247 0.088
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.088
signal transduction by phosphorylation GO:0023014 297 0.086
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.086
positive regulation of mapk cascade GO:0043410 190 0.085
regulation of cell differentiation GO:0045595 393 0.080
cellular response to cytokine stimulus GO:0071345 181 0.080
regulation of mapk cascade GO:0043408 262 0.078
purine containing compound catabolic process GO:0072523 411 0.076
Human
small gtpase mediated signal transduction GO:0007264 78 0.076
positive regulation of cytokine production GO:0001819 167 0.075
Human
purine nucleotide catabolic process GO:0006195 405 0.074
Human
response to biotic stimulus GO:0009607 276 0.074
Human Mouse
positive regulation of transferase activity GO:0051347 227 0.074
positive regulation of protein kinase activity GO:0045860 190 0.071
positive regulation of programmed cell death GO:0043068 249 0.070
Human
secretion GO:0046903 254 0.069
Mouse
positive regulation of stress activated mapk cascade GO:0032874 60 0.066
organophosphate catabolic process GO:0046434 430 0.066
Human
system process GO:0003008 349 0.065
Human
response to external biotic stimulus GO:0043207 261 0.065
Human Mouse
protein modification by small protein conjugation GO:0032446 342 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.064
positive regulation of map kinase activity GO:0043406 80 0.063
positive regulation of cell death GO:0010942 263 0.063
Human
cdc42 protein signal transduction GO:0032488 4 0.062
regulation of cellular ketone metabolic process GO:0010565 50 0.061
ribonucleoside triphosphate metabolic process GO:0009199 412 0.060
Human
positive regulation of kinase activity GO:0033674 204 0.060
regulation of protein kinase activity GO:0045859 289 0.059
immune response GO:0006955 307 0.058
response to cytokine GO:0034097 232 0.058
amine metabolic process GO:0009308 44 0.057
regulation of proteolysis GO:0030162 293 0.057
Human
positive regulation of developmental process GO:0051094 314 0.057
rho protein signal transduction GO:0007266 26 0.057
ribonucleoside triphosphate catabolic process GO:0009203 391 0.056
Human
metal ion homeostasis GO:0055065 169 0.056
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.055
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.054
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.054
Human
post embryonic development GO:0009791 2 0.053
guanosine containing compound catabolic process GO:1901069 239 0.053
Human
positive regulation of apoptotic process GO:0043065 246 0.053
Human
cellular lipid metabolic process GO:0044255 303 0.052
nucleotide catabolic process GO:0009166 408 0.052
Human
immune response activating signal transduction GO:0002757 90 0.052
positive regulation of immune system process GO:0002684 283 0.052
purine nucleoside catabolic process GO:0006152 398 0.052
Human
positive regulation of cell differentiation GO:0045597 211 0.051
defense response GO:0006952 315 0.050
Mouse
activation of immune response GO:0002253 114 0.050
immune system development GO:0002520 195 0.049
immune response regulating signaling pathway GO:0002764 97 0.048
ion homeostasis GO:0050801 230 0.048
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.048
Human
protein autoubiquitination GO:0051865 37 0.047
locomotory behavior GO:0007626 1 0.047
negative regulation of neurological system process GO:0031645 2 0.046
Human
regulation of cellular response to stress GO:0080135 244 0.046
purine ribonucleotide catabolic process GO:0009154 404 0.045
Human
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.045
cellular cation homeostasis GO:0030003 163 0.045
Human
positive regulation of jnk cascade GO:0046330 52 0.045
myeloid cell differentiation GO:0030099 117 0.045
protein polyubiquitination GO:0000209 110 0.044
regulation of immune response GO:0050776 201 0.044
regulation of secretion by cell GO:1903530 177 0.043
ribonucleotide catabolic process GO:0009261 405 0.043
Human
cellular response to lipid GO:0071396 127 0.043
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.043
response to tumor necrosis factor GO:0034612 76 0.042
cellular divalent inorganic cation homeostasis GO:0072503 128 0.042
Human
cytokine mediated signaling pathway GO:0019221 109 0.041
activation of protein kinase activity GO:0032147 90 0.041
response to abiotic stimulus GO:0009628 336 0.041
Human
lipid metabolic process GO:0006629 381 0.041
positive regulation of catabolic process GO:0009896 310 0.040
Human
ras protein signal transduction GO:0007265 73 0.040
cation transport GO:0006812 331 0.040
regulation of cell motility GO:2000145 299 0.039
multicellular organismal aging GO:0010259 3 0.039
regulation of cellular component movement GO:0051270 334 0.039
purine nucleoside triphosphate metabolic process GO:0009144 412 0.039
Human
cellular homeostasis GO:0019725 196 0.039
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.039
Human
positive regulation of transport GO:0051050 336 0.038
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.038
guanosine containing compound metabolic process GO:1901068 244 0.038
Human
regulation of stress activated mapk cascade GO:0032872 84 0.038
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.037
secretion by cell GO:0032940 226 0.037
regulation of cell migration GO:0030334 289 0.037
calcium ion homeostasis GO:0055074 122 0.037
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.037
cellular ion homeostasis GO:0006873 168 0.037
Human
purine ribonucleoside catabolic process GO:0046130 398 0.037
Human
regulation of gtpase activity GO:0043087 180 0.037
Human
apoptotic signaling pathway GO:0097190 268 0.037
Human
protein oligomerization GO:0051259 173 0.037
regulation of cellular amine metabolic process GO:0033238 11 0.036
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.036
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.036
Human
positive regulation of nucleoside metabolic process GO:0045979 186 0.036
Human
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.036
Human
positive regulation of immune response GO:0050778 159 0.036
positive regulation of cell proliferation GO:0008284 301 0.036
myeloid leukocyte differentiation GO:0002573 60 0.036
nucleoside catabolic process GO:0009164 408 0.035
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.035
regulation of myeloid cell differentiation GO:0045637 81 0.035
regulation of secretion GO:0051046 194 0.035
Mouse
hemopoiesis GO:0030097 180 0.035
protein catabolic process GO:0030163 325 0.034
Human
positive regulation of cellular catabolic process GO:0031331 284 0.034
Human
positive regulation of gtpase activity GO:0043547 166 0.034
Human
regulation of locomotion GO:0040012 329 0.034
cellular response to tumor necrosis factor GO:0071356 63 0.034
negative regulation of phosphorus metabolic process GO:0010563 267 0.034
cellular metal ion homeostasis GO:0006875 146 0.033
Human
regulation of purine nucleotide catabolic process GO:0033121 205 0.033
Human
regulation of ras protein signal transduction GO:0046578 155 0.033
Human
negative regulation of multicellular organismal process GO:0051241 317 0.033
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.032
positive regulation of hydrolase activity GO:0051345 331 0.032
Human
cation homeostasis GO:0055080 189 0.032
Human
gtp catabolic process GO:0006184 237 0.032
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.032
cellular response to biotic stimulus GO:0071216 71 0.032
Human
regulation of binding GO:0051098 111 0.031
negative regulation of apoptotic process GO:0043066 316 0.031
nervous system development GO:0007399 293 0.031
Human
cellular chemical homeostasis GO:0055082 180 0.031
Human
chemical homeostasis GO:0048878 306 0.031
Human
cellular response to molecule of bacterial origin GO:0071219 62 0.031
Human
regulation of jnk cascade GO:0046328 73 0.031
regulation of hormone levels GO:0010817 125 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.031
divalent inorganic cation homeostasis GO:0072507 136 0.031
Human
regulation of response to external stimulus GO:0032101 222 0.031
Mouse
cellular calcium ion homeostasis GO:0006874 117 0.030
Human
positive regulation of cellular component organization GO:0051130 376 0.030
regulation of small gtpase mediated signal transduction GO:0051056 156 0.030
Human
regulation of gtp catabolic process GO:0033124 180 0.030
Human
cardiovascular system development GO:0072358 262 0.030
segmentation GO:0035282 4 0.030
vesicle mediated transport GO:0016192 371 0.029
cellular response to lipopolysaccharide GO:0071222 57 0.029
Human
transmembrane transport GO:0055085 399 0.029
biological adhesion GO:0022610 331 0.029
negative regulation of protein metabolic process GO:0051248 391 0.029
negative regulation of developmental process GO:0051093 247 0.029
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.029
Human
ion transmembrane transport GO:0034220 338 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
regulation of jun kinase activity GO:0043506 27 0.029
regulation of immune effector process GO:0002697 91 0.029
response to interleukin 1 GO:0070555 47 0.029
Mouse
protein homooligomerization GO:0051260 100 0.029
determination of adult lifespan GO:0008340 2 0.029
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.028
regulation of protein transport GO:0051223 213 0.028
positive regulation of ras gtpase activity GO:0032320 117 0.028
Human
neuromuscular junction development GO:0007528 3 0.028
regulation of protein binding GO:0043393 66 0.028
jnk cascade GO:0007254 80 0.028
immune effector process GO:0002252 159 0.027
single organism membrane organization GO:0044802 268 0.027
epithelium development GO:0060429 227 0.027
single organism cellular localization GO:1902580 332 0.026
enzyme linked receptor protein signaling pathway GO:0007167 303 0.026
innate immune response GO:0045087 178 0.026
female gamete generation GO:0007292 2 0.026
cell development GO:0048468 328 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
response to bacterium GO:0009617 144 0.025
Human Mouse
memory GO:0007613 3 0.025
adult locomotory behavior GO:0008344 1 0.025
nitrogen compound transport GO:0071705 191 0.025
hematopoietic or lymphoid organ development GO:0048534 186 0.025
cell morphogenesis GO:0000902 296 0.025
g protein coupled receptor signaling pathway GO:0007186 207 0.025
cellular component morphogenesis GO:0032989 314 0.025
positive regulation of gtp catabolic process GO:0033126 166 0.025
Human
metal ion transport GO:0030001 272 0.025
extrinsic apoptotic signaling pathway GO:0097191 119 0.025
Human
interleukin 2 production GO:0032623 20 0.025
actin filament based process GO:0030029 224 0.025
response to molecule of bacterial origin GO:0002237 82 0.025
Human Mouse
carbohydrate metabolic process GO:0005975 207 0.025
oogenesis GO:0048477 2 0.025
positive regulation of apoptotic signaling pathway GO:2001235 70 0.024
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.024
stress activated mapk cascade GO:0051403 93 0.024
positive regulation of synaptic transmission GO:0050806 4 0.023
regulation of map kinase activity GO:0043405 108 0.023
cytoplasmic transport GO:0016482 379 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.023
Human
peptidyl tyrosine modification GO:0018212 170 0.023
Human
cellular response to endogenous stimulus GO:0071495 336 0.023
response to lipopolysaccharide GO:0032496 70 0.023
Human Mouse
response to nitrogen compound GO:1901698 184 0.023
positive regulation of locomotion GO:0040017 186 0.023
membrane organization GO:0061024 292 0.023
regulation of leukocyte mediated immunity GO:0002703 38 0.023
positive regulation of secretion by cell GO:1903532 108 0.023
inorganic ion transmembrane transport GO:0098660 231 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
cell adhesion GO:0007155 325 0.022
negative regulation of cell death GO:0060548 345 0.022
cellular response to external stimulus GO:0071496 111 0.022
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
Human
regulation of protein localization GO:0032880 296 0.022
regulation of system process GO:0044057 101 0.022
Human
inorganic cation transmembrane transport GO:0098662 194 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
neurotransmitter secretion GO:0007269 4 0.022
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
mitotic cell cycle GO:0000278 326 0.021
oxidation reduction process GO:0055114 396 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
regulation of cell cycle GO:0051726 393 0.021
negative regulation of protein modification process GO:0031400 200 0.021
blastoderm segmentation GO:0007350 2 0.021
cell projection organization GO:0030030 252 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
cell fate determination GO:0001709 3 0.021
positive regulation of proteolysis GO:0045862 142 0.021
Human
monocarboxylic acid metabolic process GO:0032787 185 0.021
cell activation GO:0001775 213 0.021
oocyte differentiation GO:0009994 2 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
Human
circulatory system development GO:0072359 262 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.020
protein maturation GO:0051604 233 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
Human
negative regulation of programmed cell death GO:0043069 321 0.020
neuroblast proliferation GO:0007405 4 0.020
lymphocyte mediated immunity GO:0002449 48 0.020
response to nitric oxide GO:0071731 4 0.020
regulation of defense response GO:0031347 154 0.020
Mouse
positive regulation of cell motility GO:2000147 177 0.020
sensory perception of pain GO:0019233 4 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
forebrain generation of neurons GO:0021872 3 0.020
dephosphorylation GO:0016311 209 0.020
positive regulation of secretion GO:0051047 116 0.020
Mouse
cation transmembrane transport GO:0098655 238 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
activation of nf kappab inducing kinase activity GO:0007250 9 0.020
embryonic epithelial tube formation GO:0001838 4 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
regeneration GO:0031099 4 0.019
stem cell division GO:0017145 2 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
positive regulation of leukocyte mediated immunity GO:0002705 24 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
endomembrane system organization GO:0010256 196 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
Human
organ formation GO:0048645 3 0.019
regulation of myeloid leukocyte differentiation GO:0002761 39 0.019
protein ubiquitination GO:0016567 314 0.019
compound eye development GO:0048749 1 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.019
regulation of synaptic plasticity GO:0048167 3 0.019
protein k63 linked ubiquitination GO:0070534 31 0.019
cell cell signaling GO:0007267 155 0.019
positive regulation of myeloid cell differentiation GO:0045639 39 0.019
positive regulation of protein catabolic process GO:0045732 75 0.018
Human
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.018
oocyte development GO:0048599 1 0.018
spermatid differentiation GO:0048515 4 0.018
cellular protein complex assembly GO:0043623 188 0.018
positive regulation of rho gtpase activity GO:0032321 56 0.018
Human
associative learning GO:0008306 1 0.018
cardiac muscle cell contraction GO:0086003 4 0.018
anterior posterior axis specification GO:0009948 2 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
Human
rhythmic behavior GO:0007622 2 0.018
lipid transport GO:0006869 90 0.018
Mouse
positive regulation of jun kinase activity GO:0043507 23 0.018
intracellular protein transport GO:0006886 270 0.018
blood vessel development GO:0001568 172 0.018
neural tube formation GO:0001841 3 0.018
regulation of ras gtpase activity GO:0032318 128 0.018
Human
somatic stem cell division GO:0048103 1 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
Human
gtp metabolic process GO:0046039 239 0.018
Human
regulation of establishment of protein localization GO:0070201 242 0.017
cellular protein catabolic process GO:0044257 261 0.017
leukocyte mediated immunity GO:0002443 59 0.017
adaptive immune response GO:0002250 49 0.017
peripheral nervous system development GO:0007422 2 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
protein localization to organelle GO:0033365 280 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
protein processing GO:0016485 226 0.017
cytokine production involved in immune response GO:0002367 27 0.017
blood vessel morphogenesis GO:0048514 162 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
response to growth factor GO:0070848 205 0.017
positive regulation of protein transport GO:0051222 135 0.017
response to organic cyclic compound GO:0014070 204 0.017
epithelial cell differentiation GO:0030855 141 0.017
cellular response to abiotic stimulus GO:0071214 117 0.017
Human
regulation of nucleotide metabolic process GO:0006140 269 0.017
Human
regulation of cytoskeleton organization GO:0051493 177 0.016
response to fungus GO:0009620 4 0.016
chromatin organization GO:0006325 351 0.016
regulation of cell cycle process GO:0010564 266 0.016
protein secretion GO:0009306 98 0.016
motor neuron axon guidance GO:0008045 2 0.016
regulation of neurotransmitter secretion GO:0046928 3 0.016
regulation of peptidase activity GO:0052547 180 0.016
hindbrain development GO:0030902 3 0.016
regulation of multi organism process GO:0043900 157 0.016
cell type specific apoptotic process GO:0097285 125 0.016
Human
nerve development GO:0021675 4 0.016
circadian behavior GO:0048512 2 0.016
spermatid development GO:0007286 4 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
Human
inner ear morphogenesis GO:0042472 4 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.016
Human
positive regulation of cellular component movement GO:0051272 181 0.016
specification of organ identity GO:0010092 3 0.016
positive regulation of nik nf kappab signaling GO:1901224 10 0.016
transmission of nerve impulse GO:0019226 11 0.016
regulation of leukocyte differentiation GO:1902105 61 0.016
response to inorganic substance GO:0010035 127 0.016
primary neural tube formation GO:0014020 3 0.016
multi organism cellular process GO:0044764 156 0.016
protein localization to membrane GO:0072657 160 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
visual behavior GO:0007632 2 0.015
small molecule biosynthetic process GO:0044283 157 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
regulation of ion transport GO:0043269 189 0.015
Mouse
organic acid biosynthetic process GO:0016053 97 0.015
chromatin modification GO:0016568 298 0.015
positive regulation of binding GO:0051099 45 0.015
mating GO:0007618 1 0.015
regulation of rho gtpase activity GO:0032319 66 0.015
Human
sequestering of metal ion GO:0051238 24 0.015
regulation of lymphocyte mediated immunity GO:0002706 33 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
anion transport GO:0006820 161 0.015
Mouse
actin cytoskeleton organization GO:0030036 207 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
actin mediated cell contraction GO:0070252 12 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
Human
organic anion transport GO:0015711 103 0.015
Mouse
regulation of cytokine production involved in immune response GO:0002718 22 0.015
antigen receptor mediated signaling pathway GO:0050851 38 0.015
maintenance of location GO:0051235 112 0.015
t cell receptor signaling pathway GO:0050852 21 0.015
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.015
negative regulation of cell cycle GO:0045786 193 0.014
muscle contraction GO:0006936 73 0.014
multicellular organismal response to stress GO:0033555 1 0.014
regulation of membrane potential GO:0042391 95 0.014
multicellular organismal signaling GO:0035637 34 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
positive regulation of organelle organization GO:0010638 195 0.014
carboxylic acid biosynthetic process GO:0046394 97 0.014
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.014
regulation of dna binding GO:0051101 37 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
fatty acid metabolic process GO:0006631 115 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
lipid biosynthetic process GO:0008610 177 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
salivary gland morphogenesis GO:0007435 4 0.014
morphogenesis of a polarized epithelium GO:0001738 3 0.014
actin filament based movement GO:0030048 17 0.014
divalent metal ion transport GO:0070838 152 0.014
response to organonitrogen compound GO:0010243 156 0.014
regulation of intracellular transport GO:0032386 195 0.014
regulation of adaptive immune response GO:0002819 33 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
sequestering of calcium ion GO:0051208 17 0.014
tripartite regional subdivision GO:0007351 2 0.014
positive regulation of osteoclast differentiation GO:0045672 9 0.014
thymus development GO:0048538 3 0.014
covalent chromatin modification GO:0016569 254 0.014
regulation of cell adhesion GO:0030155 166 0.014
neurological system process GO:0050877 163 0.014
Human
positive regulation of defense response GO:0031349 87 0.014
Mouse
regulation of osteoclast differentiation GO:0045670 18 0.014
spinal cord development GO:0021510 4 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
positive regulation of leukocyte differentiation GO:1902107 37 0.013
positive regulation of protein binding GO:0032092 24 0.013
negative regulation of transferase activity GO:0051348 124 0.013
tube closure GO:0060606 3 0.013
hormone metabolic process GO:0042445 61 0.013
lipid localization GO:0010876 106 0.013
Mouse
growth GO:0040007 202 0.013
histone modification GO:0016570 251 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
negative regulation of immune system process GO:0002683 136 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.013
Human
interspecies interaction between organisms GO:0044419 156 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
regulation of protein complex assembly GO:0043254 147 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
positive regulation of immune effector process GO:0002699 40 0.013
regulation of lymphocyte activation GO:0051249 103 0.013
central nervous system development GO:0007417 123 0.013
glycerolipid metabolic process GO:0046486 107 0.013
somatic stem cell maintenance GO:0035019 4 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
neurogenesis GO:0022008 169 0.013
endosomal transport GO:0016197 129 0.013
leukocyte migration GO:0050900 107 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
Human
nik nf kappab signaling GO:0038061 12 0.013
regulation of cell development GO:0060284 161 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
negative regulation of kinase activity GO:0033673 106 0.013
regulation of protein maturation GO:1903317 150 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.013
endocytosis GO:0006897 159 0.013
protein targeting GO:0006605 187 0.013
muscle system process GO:0003012 81 0.013
calcium ion transport GO:0006816 147 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
vasculature development GO:0001944 181 0.013
mitotic cell cycle process GO:1903047 286 0.013
plasma membrane organization GO:0007009 115 0.013
t cell cytokine production GO:0002369 12 0.013
cell division GO:0051301 168 0.013
metencephalon development GO:0022037 2 0.013
epithelial cell proliferation GO:0050673 128 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
nuclear transport GO:0051169 179 0.013
viral process GO:0016032 146 0.013
divalent inorganic cation transport GO:0072511 158 0.013
single organism cell adhesion GO:0098602 179 0.013
endodermal cell fate commitment GO:0001711 4 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
inflammatory response GO:0006954 79 0.012
Mouse
establishment of protein localization to membrane GO:0090150 121 0.012
regulation of nervous system development GO:0051960 88 0.012
Human
lymphocyte activation GO:0046649 133 0.012
regulation of actin filament based process GO:0032970 141 0.012
sulfur compound metabolic process GO:0006790 101 0.012
establishment of planar polarity GO:0001736 3 0.012

TNFRSF11A disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.027
sensory system disease DOID:0050155 203 0.025
nervous system disease DOID:863 431 0.025
musculoskeletal system disease DOID:17 223 0.024
inherited metabolic disorder DOID:655 242 0.024
eye and adnexa disease DOID:1492 150 0.021
eye disease DOID:5614 149 0.021
central nervous system disease DOID:331 186 0.019
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.019
connective tissue disease DOID:65 109 0.016
cardiovascular system disease DOID:1287 106 0.016
immune system disease DOID:2914 155 0.015
hematopoietic system disease DOID:74 100 0.015
retinal disease DOID:5679 118 0.015
bone disease DOID:0080001 88 0.014