Homo sapiens

9 known processes

GPI

glucose-6-phosphate isomerase

(Aliases: PHI,SA36,DKFZp686C13233,SA-36,GNPI,PGI,NLK,AMF)

GPI biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 185 0.998
Mouse
oxidation reduction process GO:0055114 396 0.993
glycolytic process GO:0006096 17 0.990
Mouse
single organism carbohydrate catabolic process GO:0044724 33 0.978
Mouse
single organism carbohydrate metabolic process GO:0044723 193 0.971
Mouse
generation of precursor metabolites and energy GO:0006091 68 0.971
Mouse
pyruvate metabolic process GO:0006090 26 0.969
Mouse
carbohydrate metabolic process GO:0005975 207 0.943
Mouse
nucleotide biosynthetic process GO:0009165 109 0.912
carbohydrate catabolic process GO:0016052 36 0.910
Mouse
organophosphate biosynthetic process GO:0090407 163 0.837
determination of adult lifespan GO:0008340 2 0.802
Worm
ribonucleotide biosynthetic process GO:0009260 81 0.713
purine ribonucleotide biosynthetic process GO:0009152 79 0.651
post embryonic development GO:0009791 2 0.611
ribonucleoside biosynthetic process GO:0042455 25 0.594
ribonucleoside monophosphate metabolic process GO:0009161 187 0.593
ribose phosphate biosynthetic process GO:0046390 82 0.546
ribonucleoside monophosphate biosynthetic process GO:0009156 17 0.498
atp biosynthetic process GO:0006754 11 0.493
oxidoreduction coenzyme metabolic process GO:0006733 19 0.489
somatic muscle development GO:0007525 1 0.484
nucleoside biosynthetic process GO:0009163 26 0.470
purine nucleoside monophosphate metabolic process GO:0009126 186 0.462
purine ribonucleoside biosynthetic process GO:0046129 23 0.455
atp metabolic process GO:0046034 176 0.406
monosaccharide metabolic process GO:0005996 74 0.379
nucleoside phosphate biosynthetic process GO:1901293 109 0.376
myoblast fusion GO:0007520 1 0.359
cellular homeostasis GO:0019725 196 0.355
fructose 1 6 bisphosphate metabolic process GO:0030388 5 0.334
response to mercury ion GO:0046689 4 0.318
system process GO:0003008 349 0.312
purine nucleotide biosynthetic process GO:0006164 84 0.308
carbohydrate derivative biosynthetic process GO:1901137 207 0.297
carbohydrate phosphorylation GO:0046835 17 0.297
multicellular organismal aging GO:0010259 3 0.294
Worm
cellular protein complex assembly GO:0043623 188 0.289
hexose metabolic process GO:0019318 55 0.274
regulation of cell cycle GO:0051726 393 0.259
regulation of mitotic cell cycle phase transition GO:1901990 118 0.249
cellular carbohydrate metabolic process GO:0044262 84 0.231
myosin filament organization GO:0031033 2 0.221
negative regulation of cell cycle process GO:0010948 121 0.216
fructose metabolic process GO:0006000 3 0.213
pyridine nucleotide metabolic process GO:0019362 14 0.200
myosin filament assembly GO:0031034 2 0.200
isocitrate metabolic process GO:0006102 1 0.188
anatomical structure homeostasis GO:0060249 100 0.185
striated muscle myosin thick filament assembly GO:0071688 2 0.178
purine ribonucleoside metabolic process GO:0046128 437 0.173
glycosyl compound biosynthetic process GO:1901659 27 0.171
organonitrogen compound biosynthetic process GO:1901566 200 0.168
nucleoside triphosphate metabolic process GO:0009141 422 0.163
anatomical structure formation involved in morphogenesis GO:0048646 284 0.163
Mouse
nadh metabolic process GO:0006734 1 0.162
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.154
purine containing compound biosynthetic process GO:0072522 88 0.150
positive regulation of protein kinase a signaling GO:0010739 4 0.134
purine nucleoside monophosphate biosynthetic process GO:0009127 16 0.133
muscle cell cellular homeostasis GO:0046716 3 0.132
cellular amino acid metabolic process GO:0006520 116 0.132
organic acid biosynthetic process GO:0016053 97 0.130
aldehyde biosynthetic process GO:0046184 3 0.128
purine nucleoside triphosphate metabolic process GO:0009144 412 0.126
nucleoside triphosphate biosynthetic process GO:0009142 20 0.125
regulation of hormone levels GO:0010817 125 0.124
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.119
protein oligomerization GO:0051259 173 0.117
somitogenesis GO:0001756 2 0.115
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.115
energy derivation by oxidation of organic compounds GO:0015980 43 0.109
regulation of nucleotide metabolic process GO:0006140 269 0.106
striated muscle contraction GO:0006941 52 0.103
purine ribonucleoside monophosphate biosynthetic process GO:0009168 16 0.102
regulation of secretion by cell GO:1903530 177 0.097
fatty acid metabolic process GO:0006631 115 0.096
coenzyme catabolic process GO:0009109 5 0.095
glucan metabolic process GO:0044042 22 0.095
cofactor metabolic process GO:0051186 87 0.094
aging GO:0007568 66 0.093
Worm
striated muscle cell differentiation GO:0051146 43 0.093
carboxylic acid catabolic process GO:0046395 71 0.092
negative regulation of cell cycle phase transition GO:1901988 89 0.092
cellular macromolecular complex assembly GO:0034622 324 0.090
cellular modified amino acid metabolic process GO:0006575 64 0.090
female gamete generation GO:0007292 2 0.089
response to decreased oxygen levels GO:0036293 96 0.088
regulation of anatomical structure morphogenesis GO:0022603 286 0.085
secretion GO:0046903 254 0.084
sulfur compound metabolic process GO:0006790 101 0.084
embryo development GO:0009790 123 0.083
Mouse Worm
purine nucleoside monophosphate catabolic process GO:0009128 158 0.077
response to abiotic stimulus GO:0009628 336 0.077
cellular respiration GO:0045333 21 0.076
glucose metabolic process GO:0006006 45 0.075
mitotic dna integrity checkpoint GO:0044774 30 0.074
neurological system process GO:0050877 163 0.073
striated muscle cell development GO:0055002 27 0.072
regulation of secretion GO:0051046 194 0.071
cell projection organization GO:0030030 252 0.068
cellular amide metabolic process GO:0043603 69 0.067
cellular response to dna damage stimulus GO:0006974 379 0.066
amine metabolic process GO:0009308 44 0.066
cell development GO:0048468 328 0.064
negative regulation of mitotic cell cycle GO:0045930 102 0.062
secretion by cell GO:0032940 226 0.059
nucleoside monophosphate metabolic process GO:0009123 191 0.057
cellular component assembly involved in morphogenesis GO:0010927 73 0.057
taxis GO:0042330 157 0.057
carboxylic acid biosynthetic process GO:0046394 97 0.056
negative regulation of catalytic activity GO:0043086 335 0.055
tricarboxylic acid cycle GO:0006099 4 0.055
syncytium formation by plasma membrane fusion GO:0000768 2 0.054
anion transport GO:0006820 161 0.054
ribonucleoside triphosphate metabolic process GO:0009199 412 0.053
regulation of atp metabolic process GO:1903578 29 0.051
regulation of cellular ketone metabolic process GO:0010565 50 0.050
cellular component morphogenesis GO:0032989 314 0.049
muscle system process GO:0003012 81 0.049
cellular amino acid catabolic process GO:0009063 31 0.048
citrate metabolic process GO:0006101 2 0.048
regulation of cell cycle process GO:0010564 266 0.046
ribonucleoside triphosphate biosynthetic process GO:0009201 12 0.046
pyridine containing compound metabolic process GO:0072524 18 0.045
segmentation GO:0035282 4 0.045
tricarboxylic acid metabolic process GO:0072350 4 0.045
epithelial cell differentiation GO:0030855 141 0.045
cell cycle checkpoint GO:0000075 117 0.044
muscle contraction GO:0006936 73 0.043
mitotic cell cycle checkpoint GO:0007093 68 0.043
negative regulation of cell cycle GO:0045786 193 0.041
apoptotic signaling pathway GO:0097190 268 0.040
dna integrity checkpoint GO:0031570 71 0.040
nervous system development GO:0007399 293 0.039
microtubule based process GO:0007017 210 0.038
organic acid catabolic process GO:0016054 71 0.038
actomyosin structure organization GO:0031032 59 0.037
lipid storage GO:0019915 28 0.037
ion homeostasis GO:0050801 230 0.036
purine ribonucleoside catabolic process GO:0046130 398 0.036
epithelium development GO:0060429 227 0.035
cell cycle phase transition GO:0044770 173 0.034
embryo development ending in birth or egg hatching GO:0009792 34 0.034
Mouse Worm
metal ion transport GO:0030001 272 0.034
response to organonitrogen compound GO:0010243 156 0.034
dicarboxylic acid metabolic process GO:0043648 29 0.034
regulation of glucose metabolic process GO:0010906 28 0.033
mitotic cell cycle phase transition GO:0044772 162 0.033
protein secretion GO:0009306 98 0.033
positive regulation of cell death GO:0010942 263 0.032
response to hypoxia GO:0001666 96 0.032
hormone secretion GO:0046879 65 0.032
protein homooligomerization GO:0051260 100 0.032
muscle cell differentiation GO:0042692 63 0.032
mitotic g2 dna damage checkpoint GO:0007095 7 0.031
behavior GO:0007610 112 0.031
cell cell signaling GO:0007267 155 0.031
regulation of nucleoside metabolic process GO:0009118 209 0.031
vesicle mediated transport GO:0016192 371 0.030
cellular response to hormone stimulus GO:0032870 125 0.030
alpha amino acid metabolic process GO:1901605 72 0.030
protein processing GO:0016485 226 0.030
ribonucleoside catabolic process GO:0042454 406 0.029
regulation of ion transmembrane transport GO:0034765 132 0.029
nitrogen compound transport GO:0071705 191 0.029
regulation of establishment of protein localization GO:0070201 242 0.028
midbrain development GO:0030901 45 0.028
maintenance of location GO:0051235 112 0.028
fructose 6 phosphate metabolic process GO:0006002 3 0.027
cation transport GO:0006812 331 0.027
microtubule cytoskeleton organization GO:0000226 176 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
regulation of cell cycle phase transition GO:1901987 126 0.027
cellular chemical homeostasis GO:0055082 180 0.027
nucleotide catabolic process GO:0009166 408 0.026
regulation of growth GO:0040008 165 0.026
response to mechanical stimulus GO:0009612 51 0.026
cell part morphogenesis GO:0032990 137 0.026
regulation of cell morphogenesis GO:0022604 153 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.025
g2 dna damage checkpoint GO:0031572 26 0.025
regulation of oxidative phosphorylation GO:0002082 3 0.025
monocarboxylic acid biosynthetic process GO:0072330 67 0.024
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.024
purine nucleoside biosynthetic process GO:0042451 23 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
response to hormone GO:0009725 175 0.024
positive regulation of protein transport GO:0051222 135 0.024
purine nucleoside triphosphate biosynthetic process GO:0009145 11 0.024
organelle assembly GO:0070925 176 0.024
nucleoside monophosphate biosynthetic process GO:0009124 19 0.024
single organism reproductive process GO:0044702 98 0.024
small molecule biosynthetic process GO:0044283 157 0.024
fatty acid derivative metabolic process GO:1901568 35 0.023
positive regulation of developmental process GO:0051094 314 0.023
regulation of fibroblast proliferation GO:0048145 32 0.023
muscle structure development GO:0061061 98 0.023
regulation of developmental growth GO:0048638 30 0.023
coenzyme metabolic process GO:0006732 65 0.023
negative regulation of organelle organization GO:0010639 126 0.023
brain development GO:0007420 97 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
regulation of mapk cascade GO:0043408 262 0.021
purine ribonucleoside triphosphate biosynthetic process GO:0009206 11 0.021
unsaturated fatty acid metabolic process GO:0033559 37 0.021
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.021
cell morphogenesis GO:0000902 296 0.021
mitotic cell cycle GO:0000278 326 0.021
icosanoid metabolic process GO:0006690 35 0.020
cellular polysaccharide metabolic process GO:0044264 27 0.020
actin filament based process GO:0030029 224 0.020
lipid localization GO:0010876 106 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
adult locomotory behavior GO:0008344 1 0.020
cellular carbohydrate biosynthetic process GO:0034637 21 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
oogenesis GO:0048477 2 0.020
response to biotic stimulus GO:0009607 276 0.019
dephosphorylation GO:0016311 209 0.019
cell adhesion GO:0007155 325 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
regeneration GO:0031099 4 0.019
myotube differentiation GO:0014902 22 0.019
small molecule catabolic process GO:0044282 92 0.019
mitotic cell cycle process GO:1903047 286 0.019
cellular ketone metabolic process GO:0042180 80 0.019
regulation of peptide transport GO:0090087 62 0.019
calcium ion homeostasis GO:0055074 122 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
ion transmembrane transport GO:0034220 338 0.018
regulation of peptidase activity GO:0052547 180 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
developmental process involved in reproduction GO:0003006 66 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
positive regulation of growth GO:0045927 58 0.018
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
myofibril assembly GO:0030239 10 0.018
somite development GO:0061053 7 0.018
aerobic respiration GO:0009060 7 0.018
prostaglandin metabolic process GO:0006693 17 0.017
translation GO:0006412 132 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
cation transmembrane transport GO:0098655 238 0.017
regulation of peptide secretion GO:0002791 42 0.017
regulation of gene expression epigenetic GO:0040029 73 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.017
growth GO:0040007 202 0.016
wnt protein secretion GO:0061355 1 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.016
multicellular organism reproduction GO:0032504 42 0.016
carbohydrate biosynthetic process GO:0016051 42 0.016
regulation of leukocyte activation GO:0002694 115 0.016
cellular ion homeostasis GO:0006873 168 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
response to oxygen containing compound GO:1901700 369 0.016
negative regulation of transport GO:0051051 176 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.016
response to metal ion GO:0010038 84 0.016
muscle cell development GO:0055001 29 0.015
protein maturation GO:0051604 233 0.015
central nervous system development GO:0007417 123 0.015
peptide transport GO:0015833 74 0.015
mammary gland morphogenesis GO:0060443 2 0.015
reproductive process GO:0022414 106 0.015
response to oxygen levels GO:0070482 100 0.015
lipid biosynthetic process GO:0008610 177 0.015
posttranscriptional gene silencing by rna GO:0035194 25 0.015
vitamin metabolic process GO:0006766 26 0.015
negative regulation of cell death GO:0060548 345 0.015
cellular response to glucocorticoid stimulus GO:0071385 4 0.015
regulation of erk1 and erk2 cascade GO:0070372 99 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
amide transport GO:0042886 76 0.015
cytokine production GO:0001816 247 0.015
cellular lipid metabolic process GO:0044255 303 0.015
fatty acid biosynthetic process GO:0006633 46 0.014
negative regulation of mapk cascade GO:0043409 56 0.014
organic hydroxy compound biosynthetic process GO:1901617 71 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
ossification GO:0001503 121 0.014
regulation of hormone secretion GO:0046883 57 0.014
aspartate metabolic process GO:0006531 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.014
reproductive system development GO:0061458 56 0.014
glomerular mesangial cell development GO:0072144 1 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
nucleobase containing compound transport GO:0015931 51 0.013
oxidative phosphorylation GO:0006119 10 0.013
cellular response to lipid GO:0071396 127 0.013
pattern specification process GO:0007389 43 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
circulatory system development GO:0072359 262 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
neurogenesis GO:0022008 169 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
response to nitrogen compound GO:1901698 184 0.012
cellular amine metabolic process GO:0044106 41 0.012
regulation of cellular response to stress GO:0080135 244 0.012
cellular glucan metabolic process GO:0006073 22 0.012
fatty acid derivative biosynthetic process GO:1901570 18 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
response to endoplasmic reticulum stress GO:0034976 49 0.012
regulation of peptide hormone secretion GO:0090276 41 0.012
cytokine secretion GO:0050663 64 0.012
gonad development GO:0008406 34 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
substantia nigra development GO:0021762 45 0.012
reproduction GO:0000003 63 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
positive regulation of lymphocyte proliferation GO:0050671 46 0.012
chemotaxis GO:0006935 157 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
dicarboxylic acid biosynthetic process GO:0043650 4 0.012
regulation of cell shape GO:0008360 48 0.012
biological adhesion GO:0022610 331 0.011
osteoblast differentiation GO:0001649 92 0.011
regulation of b cell activation GO:0050864 24 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
regulation of cellular amide metabolic process GO:0034248 9 0.011
negative regulation of secretion by cell GO:1903531 52 0.011
mitochondrion organization GO:0007005 156 0.011
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.011
positive regulation of catabolic process GO:0009896 310 0.011
neural nucleus development GO:0048857 47 0.011
regulation of organ morphogenesis GO:2000027 24 0.011
regulation of protein processing GO:0070613 150 0.011
response to other organism GO:0051707 261 0.011
lipid metabolic process GO:0006629 381 0.011
organic acid transport GO:0015849 65 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
rna interference GO:0016246 4 0.011
lymphocyte activation GO:0046649 133 0.011
regulation of transporter activity GO:0032409 82 0.011
regulation of transmembrane transport GO:0034762 139 0.011
leukocyte proliferation GO:0070661 74 0.011
unsaturated fatty acid biosynthetic process GO:0006636 21 0.011
positive regulation of b cell proliferation GO:0030890 12 0.011
calcium ion transport GO:0006816 147 0.010
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.010
regulation of cytokine production GO:0001817 232 0.010
negative regulation of developmental process GO:0051093 247 0.010
regulation of oxidoreductase activity GO:0051341 43 0.010
developmental growth GO:0048589 48 0.010
protein kinase a signaling GO:0010737 9 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
immune response GO:0006955 307 0.010

GPI disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.289
carbohydrate metabolism disease DOID:0050013 32 0.289
acquired metabolic disease DOID:0060158 58 0.289
glucose metabolism disease DOID:4194 32 0.130
amino acid metabolic disorder DOID:9252 50 0.114
inherited metabolic disorder DOID:655 242 0.114
central nervous system disease DOID:331 186 0.016
nervous system disease DOID:863 431 0.016
neurodegenerative disease DOID:1289 102 0.014
retinal disease DOID:5679 118 0.012
sensory system disease DOID:0050155 203 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
immune system disease DOID:2914 155 0.002
hematopoietic system disease DOID:74 100 0.001
hemolytic anemia DOID:583 20 0.001
normocytic anemia DOID:720 20 0.001
anemia DOID:2355 55 0.001
congenital hemolytic anemia DOID:589 9 0.000