Homo sapiens

0 known processes

GBP4

guanylate binding protein 4

(Aliases: Mpa2)

GBP4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to cytokine GO:0034097 232 0.664
Mouse
immune response GO:0006955 307 0.549
Mouse
response to biotic stimulus GO:0009607 276 0.430
Mouse
response to external biotic stimulus GO:0043207 261 0.265
Mouse
cellular response to interferon gamma GO:0071346 24 0.257
Mouse
cellular response to cytokine stimulus GO:0071345 181 0.239
Mouse
response to other organism GO:0051707 261 0.233
Mouse
defense response to other organism GO:0098542 129 0.229
Mouse
cell activation GO:0001775 213 0.220
response to interferon gamma GO:0034341 39 0.217
Mouse
defense response GO:0006952 315 0.214
Mouse
leukocyte activation GO:0045321 164 0.200
interspecies interaction between organisms GO:0044419 156 0.198
Mouse
innate immune response GO:0045087 178 0.153
Mouse
biological adhesion GO:0022610 331 0.149
Mouse
cellular response to interferon beta GO:0035458 6 0.145
Mouse
regulation of cell activation GO:0050865 125 0.141
cytokine production GO:0001816 247 0.125
positive regulation of immune system process GO:0002684 283 0.116
chemical homeostasis GO:0048878 306 0.112
immune effector process GO:0002252 159 0.101
defense response to bacterium GO:0042742 63 0.095
Mouse
positive regulation of immune response GO:0050778 159 0.090
leukocyte differentiation GO:0002521 98 0.082
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.080
Mouse
intracellular protein transport GO:0006886 270 0.078
multi organism cellular process GO:0044764 156 0.075
regulation of leukocyte activation GO:0002694 115 0.075
cytokine mediated signaling pathway GO:0019221 109 0.075
response to interferon beta GO:0035456 11 0.073
Mouse
positive regulation of programmed cell death GO:0043068 249 0.073
regulation of immune response GO:0050776 201 0.070
inorganic anion transmembrane transport GO:0098661 47 0.069
positive regulation of transport GO:0051050 336 0.068
inorganic ion transmembrane transport GO:0098660 231 0.064
regulation of body fluid levels GO:0050878 99 0.062
t cell activation GO:0042110 99 0.061
chloride transport GO:0006821 41 0.059
regulation of cell differentiation GO:0045595 393 0.059
lymphocyte activation GO:0046649 133 0.057
negative regulation of developmental process GO:0051093 247 0.056
positive regulation of cell death GO:0010942 263 0.055
positive regulation of cytokine production GO:0001819 167 0.055
negative regulation of protein metabolic process GO:0051248 391 0.052
regulation of secretion GO:0051046 194 0.051
negative regulation of multicellular organismal process GO:0051241 317 0.051
response to abiotic stimulus GO:0009628 336 0.050
nucleoside triphosphate metabolic process GO:0009141 422 0.050
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.050
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.048
immune system development GO:0002520 195 0.047
response to virus GO:0009615 126 0.047
response to nitrogen compound GO:1901698 184 0.047
negative regulation of cell proliferation GO:0008285 228 0.045
purine containing compound catabolic process GO:0072523 411 0.045
hemopoiesis GO:0030097 180 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
regulation of protein localization GO:0032880 296 0.044
negative regulation of intracellular signal transduction GO:1902532 183 0.044
purine nucleoside triphosphate catabolic process GO:0009146 392 0.043
positive regulation of developmental process GO:0051094 314 0.043
detection of muramyl dipeptide GO:0032498 1 0.043
cellular response to oxygen containing compound GO:1901701 276 0.042
purine ribonucleotide catabolic process GO:0009154 404 0.041
anatomical structure formation involved in morphogenesis GO:0048646 284 0.041
cell fate determination GO:0001709 3 0.041
regulation of mononuclear cell proliferation GO:0032944 65 0.040
negative regulation of apoptotic process GO:0043066 316 0.040
ribonucleoside triphosphate catabolic process GO:0009203 391 0.039
negative regulation of response to external stimulus GO:0032102 83 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.039
hematopoietic or lymphoid organ development GO:0048534 186 0.038
cellular response to nitrogen compound GO:1901699 144 0.038
positive regulation of innate immune response GO:0045089 79 0.038
guanosine containing compound catabolic process GO:1901069 239 0.038
negative regulation of immune system process GO:0002683 136 0.037
cell adhesion GO:0007155 325 0.037
negative regulation of catalytic activity GO:0043086 335 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
cytoplasmic transport GO:0016482 379 0.037
regulation of t helper 2 cell cytokine production GO:2000551 2 0.037
purine nucleoside triphosphate metabolic process GO:0009144 412 0.037
regulation of dna metabolic process GO:0051052 153 0.036
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.036
positive regulation of hydrolase activity GO:0051345 331 0.036
defense response to gram positive bacterium GO:0050830 29 0.036
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
regulation of protein transport GO:0051223 213 0.036
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.035
regulation of angiogenesis GO:0045765 92 0.035
cardiovascular system development GO:0072358 262 0.035
cellular homeostasis GO:0019725 196 0.035
circulatory system development GO:0072359 262 0.035
regulation of cell adhesion GO:0030155 166 0.035
cellular amino acid metabolic process GO:0006520 116 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
vesicle mediated transport GO:0016192 371 0.033
cellular ketone metabolic process GO:0042180 80 0.033
glycosylation GO:0070085 71 0.033
regulation of cytokine production GO:0001817 232 0.033
positive regulation of cellular amine metabolic process GO:0033240 7 0.032
ras protein signal transduction GO:0007265 73 0.032
post embryonic development GO:0009791 2 0.032
anion transport GO:0006820 161 0.032
glycosyl compound catabolic process GO:1901658 413 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
angiogenesis GO:0001525 147 0.031
positive regulation of cellular component organization GO:0051130 376 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
organophosphate biosynthetic process GO:0090407 163 0.030
regulation of cell migration GO:0030334 289 0.030
response to bacterium GO:0009617 144 0.030
Mouse
negative regulation of cellular component organization GO:0051129 235 0.030
regulation of protein secretion GO:0050708 86 0.030
rho protein signal transduction GO:0007266 26 0.030
purine ribonucleoside catabolic process GO:0046130 398 0.029
secretion by cell GO:0032940 226 0.029
nucleotide catabolic process GO:0009166 408 0.029
regulation of response to external stimulus GO:0032101 222 0.029
system process GO:0003008 349 0.029
regulation of anatomical structure morphogenesis GO:0022603 286 0.029
activation of immune response GO:0002253 114 0.028
positive regulation of secretion GO:0051047 116 0.028
organophosphate catabolic process GO:0046434 430 0.028
regulation of secretion by cell GO:1903530 177 0.028
response to oxygen containing compound GO:1901700 369 0.028
regulation of transferase activity GO:0051338 355 0.028
negative regulation of cell cycle GO:0045786 193 0.028
negative regulation of vasculature development GO:1901343 43 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
negative regulation of apoptotic signaling pathway GO:2001234 97 0.027
positive regulation of cytoplasmic transport GO:1903651 82 0.027
secretion GO:0046903 254 0.027
regulation of cellular amine metabolic process GO:0033238 11 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
positive regulation of phosphorylation GO:0042327 394 0.026
hemostasis GO:0007599 76 0.026
sequestering of metal ion GO:0051238 24 0.026
extracellular transport GO:0006858 4 0.026
immune response activating signal transduction GO:0002757 90 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
regulation of leukocyte proliferation GO:0070663 67 0.025
protein secretion GO:0009306 98 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.025
vasculature development GO:0001944 181 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.024
cellular chemical homeostasis GO:0055082 180 0.024
regulation of peptidase activity GO:0052547 180 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
cellular amine metabolic process GO:0044106 41 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
positive regulation of cell differentiation GO:0045597 211 0.024
ion homeostasis GO:0050801 230 0.024
regulation of immune effector process GO:0002697 91 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
maintenance of location GO:0051235 112 0.023
cation homeostasis GO:0055080 189 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
regulation of endopeptidase activity GO:0052548 170 0.023
protein targeting GO:0006605 187 0.023
transmembrane transport GO:0055085 399 0.023
myoblast fusion GO:0007520 1 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
chemotaxis GO:0006935 157 0.023
regulation of lymphocyte activation GO:0051249 103 0.023
amine metabolic process GO:0009308 44 0.023
protein localization to organelle GO:0033365 280 0.023
regulation of cell cycle GO:0051726 393 0.022
cation transport GO:0006812 331 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
cytolysis GO:0019835 8 0.022
positive regulation of leukocyte activation GO:0002696 80 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
positive regulation of protein transport GO:0051222 135 0.022
apoptotic signaling pathway GO:0097190 268 0.022
negative regulation of cell death GO:0060548 345 0.022
response to organic cyclic compound GO:0014070 204 0.022
negative regulation of cell differentiation GO:0045596 171 0.022
regulation of cellular component movement GO:0051270 334 0.022
signal transduction by phosphorylation GO:0023014 297 0.022
single organism cellular localization GO:1902580 332 0.022
negative regulation of protein maturation GO:1903318 142 0.022
positive regulation of catabolic process GO:0009896 310 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
regulation of cytoplasmic transport GO:1903649 149 0.021
positive regulation of intracellular protein transport GO:0090316 76 0.021
regulation of cell motility GO:2000145 299 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.021
nucleoside catabolic process GO:0009164 408 0.021
chloride transmembrane transport GO:1902476 38 0.021
cell chemotaxis GO:0060326 112 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
taxis GO:0042330 157 0.020
negative regulation of blood vessel morphogenesis GO:2000181 41 0.020
calcium ion homeostasis GO:0055074 122 0.020
negative regulation of transport GO:0051051 176 0.020
blood vessel morphogenesis GO:0048514 162 0.020
positive regulation of intracellular transport GO:0032388 104 0.020
blood vessel development GO:0001568 172 0.020
defense response to virus GO:0051607 71 0.020
response to tumor necrosis factor GO:0034612 76 0.020
positive regulation of locomotion GO:0040017 186 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
regulation of protein kinase activity GO:0045859 289 0.019
negative regulation of angiogenesis GO:0016525 39 0.019
regulation of intracellular transport GO:0032386 195 0.019
compound eye development GO:0048749 1 0.019
regulation of cell development GO:0060284 161 0.019
cell cycle arrest GO:0007050 71 0.019
viral life cycle GO:0019058 132 0.019
divalent inorganic cation homeostasis GO:0072507 136 0.019
negative regulation of leukocyte activation GO:0002695 26 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
immune response regulating signaling pathway GO:0002764 97 0.019
regulation of mapk cascade GO:0043408 262 0.019
positive regulation of cell proliferation GO:0008284 301 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
response to organonitrogen compound GO:0010243 156 0.018
positive regulation of secretion by cell GO:1903532 108 0.018
receptor metabolic process GO:0043112 81 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
regulation of cell cell adhesion GO:0022407 57 0.018
divalent inorganic cation transport GO:0072511 158 0.018
protein maturation GO:0051604 233 0.018
multicellular organismal aging GO:0010259 3 0.018
positive regulation of cell motility GO:2000147 177 0.018
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.018
regulation of kinase activity GO:0043549 314 0.018
positive regulation of transferase activity GO:0051347 227 0.018
regulation of mhc class ii biosynthetic process GO:0045346 4 0.018
positive regulation of cell migration GO:0030335 172 0.018
negative regulation of cell activation GO:0050866 33 0.018
female gamete generation GO:0007292 2 0.018
protein localization to membrane GO:0072657 160 0.017
endocytosis GO:0006897 159 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
single organism membrane organization GO:0044802 268 0.017
myeloid leukocyte differentiation GO:0002573 60 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.017
memory GO:0007613 3 0.017
wound healing GO:0042060 115 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
positive regulation of proteolysis GO:0045862 142 0.017
innate immune response activating signal transduction GO:0002758 48 0.017
regulation of innate immune response GO:0045088 97 0.017
cellular response to organic cyclic compound GO:0071407 127 0.017
determination of adult lifespan GO:0008340 2 0.017
nuclear transport GO:0051169 179 0.017
regulation of vasculature development GO:1901342 97 0.017
cell cycle phase transition GO:0044770 173 0.017
cellular cation homeostasis GO:0030003 163 0.017
regulation of cellular component biogenesis GO:0044087 281 0.016
cell development GO:0048468 328 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
spermatid differentiation GO:0048515 4 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
cellular component morphogenesis GO:0032989 314 0.016
inorganic anion transport GO:0015698 60 0.016
cellular response to abiotic stimulus GO:0071214 117 0.016
regulation of protein serine threonine kinase activity GO:0071900 179 0.016
response to phenylpropanoid GO:0080184 1 0.016
positive regulation of kinase activity GO:0033674 204 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
locomotory behavior GO:0007626 1 0.016
response to radiation GO:0009314 151 0.016
regulation of multi organism process GO:0043900 157 0.016
spermatid development GO:0007286 4 0.016
ion transmembrane transport GO:0034220 338 0.016
positive regulation of protein localization to nucleus GO:1900182 48 0.016
response to molecule of bacterial origin GO:0002237 82 0.016
positive regulation of stress activated mapk cascade GO:0032874 60 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
syncytium formation by plasma membrane fusion GO:0000768 2 0.016
platelet activation GO:0030168 44 0.015
cellular metal ion homeostasis GO:0006875 146 0.015
gtp catabolic process GO:0006184 237 0.015
negative regulation of viral genome replication GO:0045071 35 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.015
neuromuscular junction development GO:0007528 3 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
negative regulation of protein modification process GO:0031400 200 0.015
positive regulation of endopeptidase activity GO:0010950 84 0.015
rna interference GO:0016246 4 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
receptor internalization GO:0031623 43 0.015
positive regulation of t cell activation GO:0050870 54 0.015
positive regulation of organelle organization GO:0010638 195 0.015
regulation of chemotaxis GO:0050920 74 0.015
regulation of protein import into nucleus GO:0042306 78 0.014
positive regulation of peptidase activity GO:0010952 88 0.014
nervous system development GO:0007399 293 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
gtp metabolic process GO:0046039 239 0.014
cytokine secretion GO:0050663 64 0.014
cellular divalent inorganic cation homeostasis GO:0072503 128 0.014
regulation of viral process GO:0050792 103 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
oogenesis GO:0048477 2 0.014
mhc class ii biosynthetic process GO:0045342 4 0.014
lipid metabolic process GO:0006629 381 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
divalent metal ion transport GO:0070838 152 0.014
negative regulation of multi organism process GO:0043901 92 0.014
anion transmembrane transport GO:0098656 76 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
regulation of locomotion GO:0040012 329 0.014
metal ion homeostasis GO:0055065 169 0.014
regulation of defense response to virus GO:0050688 33 0.014
pattern recognition receptor signaling pathway GO:0002221 48 0.014
protein import into nucleus GO:0006606 104 0.014
negative regulation of interleukin 1 secretion GO:0050711 4 0.014
blood coagulation GO:0007596 76 0.014
positive regulation of homeostatic process GO:0032846 47 0.014
guanosine containing compound metabolic process GO:1901068 244 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
cellular response to lipid GO:0071396 127 0.013
mitotic cell cycle GO:0000278 326 0.013
regulation of protein maturation GO:1903317 150 0.013
protein localization to nucleus GO:0034504 136 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
regulation of defense response to virus by host GO:0050691 22 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
protein targeting to nucleus GO:0044744 104 0.013
regulation of protein catabolic process GO:0042176 155 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
cellular ion homeostasis GO:0006873 168 0.013
rna processing GO:0006396 255 0.013
protein ubiquitination GO:0016567 314 0.013
establishment of planar polarity GO:0001736 3 0.012
cell type specific apoptotic process GO:0097285 125 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
cellular lipid metabolic process GO:0044255 303 0.012
circadian behavior GO:0048512 2 0.012
regulation of interleukin 10 secretion GO:2001179 4 0.012
cell morphogenesis GO:0000902 296 0.012
jnk cascade GO:0007254 80 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
nuclear import GO:0051170 106 0.012
regulation of protein binding GO:0043393 66 0.012
erk1 and erk2 cascade GO:0070371 104 0.012
mitotic cell cycle process GO:1903047 286 0.012
regulation of lymphocyte proliferation GO:0050670 64 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
regulation of defense response GO:0031347 154 0.012
cellular calcium ion homeostasis GO:0006874 117 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.012
muscle structure development GO:0061061 98 0.012
cellular response to biotic stimulus GO:0071216 71 0.012
cellular response to interferon alpha GO:0035457 4 0.012
regulation of proteolysis GO:0030162 293 0.012
regulation of nervous system development GO:0051960 88 0.012
regulation of protein localization to nucleus GO:1900180 85 0.012
protein catabolic process GO:0030163 325 0.012
peripheral nervous system development GO:0007422 2 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
regulation of binding GO:0051098 111 0.011
cellular protein catabolic process GO:0044257 261 0.011
chromatin modification GO:0016568 298 0.011
response to mechanical stimulus GO:0009612 51 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
coagulation GO:0050817 78 0.011
activation of innate immune response GO:0002218 55 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
regulation of camp metabolic process GO:0030814 52 0.011
response to growth factor GO:0070848 205 0.011
monosaccharide metabolic process GO:0005996 74 0.011
cyclic nucleotide metabolic process GO:0009187 82 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
leukocyte migration GO:0050900 107 0.011
cellular protein complex assembly GO:0043623 188 0.011
cell substrate adhesion GO:0031589 132 0.011
positive regulation of cell activation GO:0050867 81 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
positive regulation of lymphocyte activation GO:0051251 73 0.011
negative regulation of cytolysis GO:0045918 3 0.011
blood circulation GO:0008015 113 0.011
regulation of erk1 and erk2 cascade GO:0070372 99 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
adaptive immune response GO:0002250 49 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
digestive system development GO:0055123 75 0.010
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.010
ubiquitin dependent protein catabolic process GO:0006511 206 0.010
response to dsrna GO:0043331 25 0.010
cell projection organization GO:0030030 252 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
negative regulation of blood pressure GO:0045776 3 0.010
positive regulation of map kinase activity GO:0043406 80 0.010
response to nutrient levels GO:0031667 81 0.010
interleukin 10 production GO:0032613 17 0.010
neurological system process GO:0050877 163 0.010
negative regulation of mhc class ii biosynthetic process GO:0045347 1 0.010
positive regulation of leukocyte differentiation GO:1902107 37 0.010
regulation of protein processing GO:0070613 150 0.010
single organism nuclear import GO:1902593 104 0.010
regulation of cellular response to stress GO:0080135 244 0.010
cytosolic calcium ion homeostasis GO:0051480 89 0.010
stress activated mapk cascade GO:0051403 93 0.010
intracellular receptor signaling pathway GO:0030522 104 0.010
myeloid cell differentiation GO:0030099 117 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010

GBP4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.021
musculoskeletal system disease DOID:17 223 0.015
urinary system disease DOID:18 40 0.014
cancer DOID:162 167 0.014
organ system cancer DOID:0050686 164 0.013
sensory system disease DOID:0050155 203 0.011
nervous system disease DOID:863 431 0.011
kidney disease DOID:557 36 0.010