Homo sapiens

33 known processes

INF2

inverted formin, FH2 and WH2 domain containing

(Aliases: FLJ22056,FSGS5,MGC13251,C14orf173,DKFZp762A0214,C14orf151,pp9484)

INF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
second messenger mediated signaling GO:0019932 78 0.253
negative regulation of camp mediated signaling GO:0043951 4 0.246
cyclic nucleotide mediated signaling GO:0019935 26 0.201
ribonucleotide catabolic process GO:0009261 405 0.191
nucleoside triphosphate catabolic process GO:0009143 394 0.152
glycosyl compound catabolic process GO:1901658 413 0.136
nucleoside catabolic process GO:0009164 408 0.135
purine nucleoside catabolic process GO:0006152 398 0.130
purine ribonucleoside metabolic process GO:0046128 437 0.120
purine ribonucleoside catabolic process GO:0046130 398 0.105
positive regulation of cellular catabolic process GO:0031331 284 0.103
nervous system development GO:0007399 293 0.103
small gtpase mediated signal transduction GO:0007264 78 0.098
cellular macromolecule catabolic process GO:0044265 380 0.095
protein catabolic process GO:0030163 325 0.095
protein polyubiquitination GO:0000209 110 0.095
cellular protein catabolic process GO:0044257 261 0.090
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.090
regulation of camp mediated signaling GO:0043949 13 0.089
ras protein signal transduction GO:0007265 73 0.089
cellular component morphogenesis GO:0032989 314 0.088
camp mediated signaling GO:0019933 23 0.086
protein monoubiquitination GO:0006513 39 0.083
protein ubiquitination GO:0016567 314 0.083
cellular amino acid metabolic process GO:0006520 116 0.081
ribonucleoside triphosphate metabolic process GO:0009199 412 0.081
purine ribonucleotide catabolic process GO:0009154 404 0.081
guanosine containing compound catabolic process GO:1901069 239 0.079
purine nucleotide catabolic process GO:0006195 405 0.076
positive regulation of hydrolase activity GO:0051345 331 0.075
rho protein signal transduction GO:0007266 26 0.074
organophosphate catabolic process GO:0046434 430 0.069
post embryonic development GO:0009791 2 0.069
nucleoside phosphate catabolic process GO:1901292 412 0.067
purine nucleoside triphosphate metabolic process GO:0009144 412 0.067
nucleoside triphosphate metabolic process GO:0009141 422 0.066
regulation of locomotion GO:0040012 329 0.066
regulation of purine nucleotide catabolic process GO:0033121 205 0.065
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.063
proteasomal protein catabolic process GO:0010498 176 0.062
gtp metabolic process GO:0046039 239 0.061
cellular ketone metabolic process GO:0042180 80 0.060
cellular amine metabolic process GO:0044106 41 0.060
regulation of cellular amine metabolic process GO:0033238 11 0.060
positive regulation of nucleotide metabolic process GO:0045981 230 0.060
regulation of nucleoside metabolic process GO:0009118 209 0.058
ribonucleoside catabolic process GO:0042454 406 0.058
amine metabolic process GO:0009308 44 0.058
cell development GO:0048468 328 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.054
cell morphogenesis GO:0000902 296 0.053
regulation of nucleotide catabolic process GO:0030811 205 0.053
regulation of cellular amino acid metabolic process GO:0006521 6 0.053
protein k48 linked ubiquitination GO:0070936 38 0.052
gtp catabolic process GO:0006184 237 0.051
modification dependent protein catabolic process GO:0019941 209 0.051
purine nucleoside triphosphate catabolic process GO:0009146 392 0.051
regulation of cellular ketone metabolic process GO:0010565 50 0.050
negative regulation of intracellular signal transduction GO:1902532 183 0.050
ribonucleoside triphosphate catabolic process GO:0009203 391 0.050
nucleotide catabolic process GO:0009166 408 0.048
neurogenesis GO:0022008 169 0.047
positive regulation of nucleotide catabolic process GO:0030813 185 0.047
regulation of cellular component movement GO:0051270 334 0.045
ubiquitin dependent protein catabolic process GO:0006511 206 0.045
positive regulation of cellular amine metabolic process GO:0033240 7 0.045
regulation of nucleotide metabolic process GO:0006140 269 0.044
regulation of cell motility GO:2000145 299 0.044
regulation of purine nucleotide metabolic process GO:1900542 264 0.043
modification dependent macromolecule catabolic process GO:0043632 212 0.043
positive regulation of gtpase activity GO:0043547 166 0.042
negative regulation of catalytic activity GO:0043086 335 0.042
cell adhesion GO:0007155 325 0.041
purine containing compound catabolic process GO:0072523 411 0.041
negative regulation of cellular component organization GO:0051129 235 0.041
regulation of protein localization GO:0032880 296 0.041
multicellular organismal aging GO:0010259 3 0.041
guanosine containing compound metabolic process GO:1901068 244 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.039
regulation of cell migration GO:0030334 289 0.038
regulation of small gtpase mediated signal transduction GO:0051056 156 0.038
microtubule based process GO:0007017 210 0.038
regulation of gtpase activity GO:0043087 180 0.038
endomembrane system organization GO:0010256 196 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.037
regulation of gtp catabolic process GO:0033124 180 0.036
vesicle mediated transport GO:0016192 371 0.036
biological adhesion GO:0022610 331 0.035
cellular protein complex assembly GO:0043623 188 0.035
negative regulation of protein metabolic process GO:0051248 391 0.034
regulation of cell differentiation GO:0045595 393 0.034
cell projection organization GO:0030030 252 0.033
cellular macromolecular complex assembly GO:0034622 324 0.032
cellular lipid metabolic process GO:0044255 303 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.032
covalent chromatin modification GO:0016569 254 0.032
positive regulation of gtp catabolic process GO:0033126 166 0.031
protein modification by small protein conjugation GO:0032446 342 0.031
positive regulation of ras gtpase activity GO:0032320 117 0.030
negative regulation of protein modification process GO:0031400 200 0.030
neuromuscular junction development GO:0007528 3 0.030
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
system process GO:0003008 349 0.030
organonitrogen compound biosynthetic process GO:1901566 200 0.030
locomotory behavior GO:0007626 1 0.030
regulation of proteolysis GO:0030162 293 0.029
taxis GO:0042330 157 0.029
apoptotic signaling pathway GO:0097190 268 0.029
purine nucleoside monophosphate metabolic process GO:0009126 186 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.028
tissue migration GO:0090130 119 0.028
negative regulation of developmental process GO:0051093 247 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.027
determination of adult lifespan GO:0008340 2 0.027
positive regulation of catabolic process GO:0009896 310 0.027
regulation of synaptic plasticity GO:0048167 3 0.026
atp catabolic process GO:0006200 157 0.026
regulation of actin cytoskeleton organization GO:0032956 116 0.026
positive regulation of transport GO:0051050 336 0.026
anatomical structure formation involved in morphogenesis GO:0048646 284 0.026
positive regulation of developmental process GO:0051094 314 0.026
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
nucleoside monophosphate metabolic process GO:0009123 191 0.026
actin cytoskeleton organization GO:0030036 207 0.026
regulation of actin filament based process GO:0032970 141 0.026
lipid metabolic process GO:0006629 381 0.026
positive regulation of phosphorylation GO:0042327 394 0.026
nucleoside monophosphate catabolic process GO:0009125 159 0.026
endocytosis GO:0006897 159 0.025
chromatin organization GO:0006325 351 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
cardiovascular system development GO:0072358 262 0.024
protein maturation GO:0051604 233 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
metal ion transport GO:0030001 272 0.024
cellular lipid catabolic process GO:0044242 65 0.024
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
regulation of ras protein signal transduction GO:0046578 155 0.023
lipid localization GO:0010876 106 0.023
lipid catabolic process GO:0016042 84 0.023
carbohydrate metabolic process GO:0005975 207 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
lipid biosynthetic process GO:0008610 177 0.023
protein processing GO:0016485 226 0.023
chemotaxis GO:0006935 157 0.023
chromatin modification GO:0016568 298 0.023
mapk cascade GO:0000165 288 0.023
ameboidal type cell migration GO:0001667 135 0.023
single organism membrane organization GO:0044802 268 0.022
epithelium migration GO:0090132 119 0.022
organelle fission GO:0048285 149 0.022
histone modification GO:0016570 251 0.022
cell morphogenesis involved in differentiation GO:0000904 144 0.022
regulation of kinase activity GO:0043549 314 0.022
mitotic cell cycle process GO:1903047 286 0.022
regulation of transferase activity GO:0051338 355 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.021
response to oxygen containing compound GO:1901700 369 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
membrane organization GO:0061024 292 0.021
secretion GO:0046903 254 0.020
positive regulation of cell proliferation GO:0008284 301 0.020
neurological system process GO:0050877 163 0.020
regulation of cellular response to stress GO:0080135 244 0.020
regulation of peptidase activity GO:0052547 180 0.020
circulatory system development GO:0072359 262 0.020
regulation of protein catabolic process GO:0042176 155 0.019
cell cell signaling GO:0007267 155 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
actin filament based process GO:0030029 224 0.019
negative regulation of organelle organization GO:0010639 126 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
endothelial cell migration GO:0043542 86 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
regulation of mapk cascade GO:0043408 262 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
cytoplasmic transport GO:0016482 379 0.019
atp metabolic process GO:0046034 176 0.019
response to abiotic stimulus GO:0009628 336 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
dephosphorylation GO:0016311 209 0.018
peptidyl tyrosine modification GO:0018212 170 0.018
plasma membrane organization GO:0007009 115 0.018
epithelial cell migration GO:0010631 119 0.018
generation of neurons GO:0048699 152 0.018
actin filament organization GO:0007015 128 0.018
cellular response to endogenous stimulus GO:0071495 336 0.018
purine nucleoside monophosphate catabolic process GO:0009128 158 0.018
memory GO:0007613 3 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
mitotic nuclear division GO:0007067 119 0.017
single organism cellular localization GO:1902580 332 0.017
glycoprotein metabolic process GO:0009100 110 0.017
cell part morphogenesis GO:0032990 137 0.017
peripheral nervous system development GO:0007422 2 0.017
positive regulation of cell motility GO:2000147 177 0.017
spermatid differentiation GO:0048515 4 0.017
positive regulation of transferase activity GO:0051347 227 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
transmembrane transport GO:0055085 399 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
defense response GO:0006952 315 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
positive regulation of cell death GO:0010942 263 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
neuron differentiation GO:0030182 138 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
cell growth GO:0016049 160 0.016
secretion by cell GO:0032940 226 0.016
cell projection morphogenesis GO:0048858 129 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
segmentation GO:0035282 4 0.016
regulation of protein complex assembly GO:0043254 147 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
protein localization to plasma membrane GO:0072659 93 0.015
maintenance of location GO:0051235 112 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
g protein coupled receptor signaling pathway GO:0007186 207 0.015
immune response GO:0006955 307 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
ion homeostasis GO:0050801 230 0.015
intracellular protein transport GO:0006886 270 0.015
regulation of protein kinase activity GO:0045859 289 0.015
chemical homeostasis GO:0048878 306 0.015
protein oligomerization GO:0051259 173 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
oocyte development GO:0048599 1 0.015
oogenesis GO:0048477 2 0.015
negative regulation of cellular component movement GO:0051271 106 0.015
negative regulation of cell migration GO:0030336 102 0.015
regeneration GO:0031099 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
negative regulation of cell death GO:0060548 345 0.014
spermatid development GO:0007286 4 0.014
divalent metal ion transport GO:0070838 152 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
positive regulation of rho gtpase activity GO:0032321 56 0.014
cation transport GO:0006812 331 0.014
positive regulation of cell cycle GO:0045787 140 0.014
oocyte differentiation GO:0009994 2 0.014
female gamete generation GO:0007292 2 0.014
cell activation GO:0001775 213 0.014
peptidyl lysine modification GO:0018205 144 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
regulation of secretion by cell GO:1903530 177 0.014
ion transmembrane transport GO:0034220 338 0.014
divalent inorganic cation transport GO:0072511 158 0.013
oxidation reduction process GO:0055114 396 0.013
epithelium development GO:0060429 227 0.013
glycerolipid metabolic process GO:0046486 107 0.013
negative regulation of proteolysis GO:0045861 132 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
organelle assembly GO:0070925 176 0.013
nerve development GO:0021675 4 0.013
calcium ion homeostasis GO:0055074 122 0.013
blood vessel development GO:0001568 172 0.013
neuron development GO:0048666 113 0.013
hemopoiesis GO:0030097 180 0.013
cellular homeostasis GO:0019725 196 0.013
cytokine production GO:0001816 247 0.013
single organism cell adhesion GO:0098602 179 0.013
regulation of neuron differentiation GO:0045664 70 0.013
regulation of secretion GO:0051046 194 0.013
protein localization to organelle GO:0033365 280 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
negative regulation of protein maturation GO:1903318 142 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
negative regulation of cell motility GO:2000146 104 0.013
rna processing GO:0006396 255 0.013
cellular cation homeostasis GO:0030003 163 0.012
glycoprotein biosynthetic process GO:0009101 91 0.012
sensory perception GO:0007600 103 0.012
protein targeting GO:0006605 187 0.012
associative learning GO:0008306 1 0.012
negative regulation of transferase activity GO:0051348 124 0.012
actin filament polymerization GO:0030041 45 0.012
response to decreased oxygen levels GO:0036293 96 0.012
nuclear transport GO:0051169 179 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
response to growth factor GO:0070848 205 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
regulation of cytokine production GO:0001817 232 0.012
central nervous system development GO:0007417 123 0.012
response to other organism GO:0051707 261 0.012
angiogenesis GO:0001525 147 0.012
neuron projection development GO:0031175 106 0.012
regulation of protein maturation GO:1903317 150 0.012
salivary gland morphogenesis GO:0007435 4 0.012
negative regulation of cell cycle GO:0045786 193 0.012
response to cytokine GO:0034097 232 0.012
regulation of protein transport GO:0051223 213 0.012
organ morphogenesis GO:0009887 147 0.012
protein autophosphorylation GO:0046777 123 0.012
regulation of axon guidance GO:1902667 3 0.012
circadian behavior GO:0048512 2 0.012
negative regulation of immune system process GO:0002683 136 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
rhythmic behavior GO:0007622 2 0.012
adult locomotory behavior GO:0008344 1 0.012
metal ion homeostasis GO:0055065 169 0.012
positive regulation of organelle organization GO:0010638 195 0.012
fatty acid metabolic process GO:0006631 115 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of phosphatase activity GO:0010921 81 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of cell activation GO:0050865 125 0.011
immune system development GO:0002520 195 0.011
protein polymerization GO:0051258 71 0.011
epithelial cell differentiation GO:0030855 141 0.011
positive regulation of cell migration GO:0030335 172 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
regulation of intracellular transport GO:0032386 195 0.011
circulatory system process GO:0003013 113 0.011
regulation of growth GO:0040008 165 0.011
growth GO:0040007 202 0.011
cell projection assembly GO:0030031 126 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
regulation of protein processing GO:0070613 150 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of rho protein signal transduction GO:0035023 79 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
regulation of lipid catabolic process GO:0050994 23 0.011
cdc42 protein signal transduction GO:0032488 4 0.011
response to oxygen levels GO:0070482 100 0.011
substrate adhesion dependent cell spreading GO:0034446 41 0.011
glycerolipid catabolic process GO:0046503 18 0.011
negative regulation of kinase activity GO:0033673 106 0.011
hindbrain development GO:0030902 3 0.011
cell division GO:0051301 168 0.011
blastoderm segmentation GO:0007350 2 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
response to organonitrogen compound GO:0010243 156 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
nitrogen compound transport GO:0071705 191 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
meiotic chromosome segregation GO:0045132 4 0.011
negative regulation of locomotion GO:0040013 118 0.011
regulation of cell projection organization GO:0031344 107 0.011
regulation of actin filament length GO:0030832 56 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
protein localization to membrane GO:0072657 160 0.011
regulation of response to wounding GO:1903034 101 0.011
dna repair GO:0006281 198 0.011
response to wounding GO:0009611 168 0.011
negative regulation of catabolic process GO:0009895 104 0.010
embryo development GO:0009790 123 0.010
positive regulation of locomotion GO:0040017 186 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010
sulfur compound metabolic process GO:0006790 101 0.010
negative regulation of protein processing GO:0010955 142 0.010
cation transmembrane transport GO:0098655 238 0.010
positive regulation of secretion GO:0051047 116 0.010
regulation of rho gtpase activity GO:0032319 66 0.010
response to organic cyclic compound GO:0014070 204 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
response to biotic stimulus GO:0009607 276 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
regulation of dephosphorylation GO:0035303 96 0.010
mitochondrion organization GO:0007005 156 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
microtubule organizing center organization GO:0031023 62 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
response to nitrogen compound GO:1901698 184 0.010
positive regulation of proteolysis GO:0045862 142 0.010
positive regulation of immune system process GO:0002684 283 0.010
blood vessel morphogenesis GO:0048514 162 0.010
regulation of defense response GO:0031347 154 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
signal release GO:0023061 70 0.010

INF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 36 0.041
urinary system disease DOID:18 40 0.041
musculoskeletal system disease DOID:17 223 0.029
muscular disease DOID:0080000 114 0.019
central nervous system disease DOID:331 186 0.016
nervous system disease DOID:863 431 0.016
immune system disease DOID:2914 155 0.016
disease of metabolism DOID:0014667 295 0.016
inherited metabolic disorder DOID:655 242 0.016
muscle tissue disease DOID:66 113 0.015
sensory system disease DOID:0050155 203 0.015
connective tissue disease DOID:65 109 0.013
myopathy DOID:423 104 0.010
eye and adnexa disease DOID:1492 150 0.010
eye disease DOID:5614 149 0.010
neuropathy DOID:870 52 0.006
neuromuscular disease DOID:440 38 0.005
charcot marie tooth disease DOID:10595 33 0.004
charcot marie tooth disease intermediate type DOID:0050543 7 0.001
glomerulonephritis DOID:2921 6 0.001
nephritis DOID:10952 6 0.001
focal segmental glomerulosclerosis DOID:1312 6 0.001
glomerulosclerosis DOID:0050851 6 0.001