|
|
pattern specification involved in kidney development
|
GO:0061004 |
1 |
1.000
|
|
|
|
renal system pattern specification
|
GO:0072048 |
1 |
1.000
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
1.000
|
|
|
|
negative regulation of glomerulus development
|
GO:0090194 |
2 |
1.000
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
1.000
|
|
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
1.000
|
|
|
|
negative regulation of cell proliferation involved in kidney development
|
GO:1901723 |
2 |
1.000
|
|
|
|
negative regulation of mesenchymal cell proliferation
|
GO:0072201 |
3 |
1.000
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
1.000
|
|
|
|
negative regulation of glucocorticoid biosynthetic process
|
GO:0031947 |
4 |
1.000
|
|
|
|
negative regulation of steroid hormone biosynthetic process
|
GO:0090032 |
4 |
1.000
|
|
|
|
branch elongation involved in ureteric bud branching
|
GO:0060681 |
2 |
1.000
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
1.000
|
Mouse |
|
|
nephric duct formation
|
GO:0072179 |
1 |
1.000
|
|
|
|
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0016338 |
2 |
1.000
|
|
|
|
negative regulation of cardiac muscle cell differentiation
|
GO:2000726 |
3 |
1.000
|
|
|
|
regulation of aldosterone biosynthetic process
|
GO:0032347 |
6 |
1.000
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
1.000
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
1.000
|
|
|
|
ureteric bud elongation
|
GO:0060677 |
2 |
1.000
|
|
|
|
ureter development
|
GO:0072189 |
3 |
1.000
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
1.000
|
|
|
|
negative regulation of glomerular mesangial cell proliferation
|
GO:0072125 |
2 |
1.000
|
|
|
|
negative regulation of mesonephros development
|
GO:0061218 |
1 |
1.000
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.999
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.999
|
|
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.999
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.999
|
Mouse |
|
|
positive regulation of p38mapk cascade
|
GO:1900745 |
8 |
0.999
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.999
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.999
|
|
|
|
nephric duct development
|
GO:0072176 |
4 |
0.999
|
|
|
|
cortisol biosynthetic process
|
GO:0034651 |
8 |
0.999
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.999
|
Mouse |
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.999
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.999
|
|
|
|
negative regulation of glucocorticoid metabolic process
|
GO:0031944 |
4 |
0.998
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.998
|
|
|
|
aldosterone biosynthetic process
|
GO:0032342 |
9 |
0.998
|
|
|
|
endodermal mesodermal cell signaling involved in heart induction
|
GO:0003134 |
3 |
0.997
|
|
|
|
bmp signaling pathway involved in heart induction
|
GO:0003130 |
3 |
0.997
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.997
|
Human |
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.997
|
|
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.997
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.996
|
Human Mouse |
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.995
|
Fly |
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.994
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.994
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.994
|
Fly |
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.993
|
|
|
|
metanephric s shaped body morphogenesis
|
GO:0072284 |
4 |
0.992
|
|
|
|
secondary heart field specification
|
GO:0003139 |
2 |
0.992
|
|
|
|
regulation of cortisol biosynthetic process
|
GO:2000064 |
5 |
0.992
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.992
|
Human |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.992
|
Human |
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.992
|
|
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.992
|
|
|
|
negative regulation of endodermal cell differentiation
|
GO:1903225 |
2 |
0.990
|
|
|
|
mineralocorticoid metabolic process
|
GO:0008212 |
9 |
0.990
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.990
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.988
|
Human |
|
|
s shaped body morphogenesis
|
GO:0072050 |
4 |
0.988
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.986
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.984
|
Mouse |
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
1 |
0.984
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.984
|
Fly |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.982
|
Human |
|
|
epithelial cell proliferation involved in lung morphogenesis
|
GO:0060502 |
3 |
0.982
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.978
|
Human |
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
7 |
0.977
|
|
|
|
renal vesicle morphogenesis
|
GO:0072077 |
4 |
0.977
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.975
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.975
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.972
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.971
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
3 |
0.971
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.971
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.970
|
|
|
|
proteoglycan metabolic process
|
GO:0006029 |
29 |
0.970
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.969
|
|
|
|
regulation of aldosterone metabolic process
|
GO:0032344 |
6 |
0.969
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.968
|
|
|
|
mineralocorticoid biosynthetic process
|
GO:0006705 |
9 |
0.968
|
|
|
|
regulation of wnt signaling pathway involved in heart development
|
GO:0003307 |
3 |
0.964
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.960
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.959
|
Human |
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.958
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.958
|
Human |
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.956
|
Human |
|
|
ketone biosynthetic process
|
GO:0042181 |
17 |
0.955
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.952
|
Human |
|
|
negative regulation of aldosterone biosynthetic process
|
GO:0032348 |
4 |
0.950
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.946
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
2 |
0.946
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.945
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.944
|
|
|
|
heart induction
|
GO:0003129 |
4 |
0.943
|
|
|
|
organ induction
|
GO:0001759 |
4 |
0.942
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.939
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.938
|
|
|
|
negative regulation of epidermal cell differentiation
|
GO:0045605 |
4 |
0.936
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.933
|
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.930
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.927
|
|
|
|
glomerular mesangial cell proliferation
|
GO:0072110 |
3 |
0.921
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.920
|
Human |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.919
|
Mouse Fly |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.918
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.917
|
|
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.911
|
|
|
|
renal vesicle development
|
GO:0072087 |
4 |
0.911
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.909
|
Human |
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.907
|
Mouse Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.903
|
|
|
|
negative regulation of metanephros development
|
GO:0072217 |
1 |
0.903
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.902
|
Human |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.902
|
Human |
|
|
branching involved in ureteric bud morphogenesis
|
GO:0001658 |
9 |
0.901
|
|
|
|
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
|
GO:0002043 |
3 |
0.893
|
|
|
|
c21 steroid hormone biosynthetic process
|
GO:0006700 |
11 |
0.893
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.893
|
|
|
|
regulation of mesonephros development
|
GO:0061217 |
3 |
0.891
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.889
|
Human Mouse |
|
|
negative regulation of cortisol biosynthetic process
|
GO:2000065 |
4 |
0.889
|
|
|
|
metanephric renal vesicle morphogenesis
|
GO:0072283 |
4 |
0.887
|
|
|
|
regulation of cardiac muscle cell differentiation
|
GO:2000725 |
7 |
0.886
|
|
|
|
branch elongation of an epithelium
|
GO:0060602 |
3 |
0.885
|
|
|
|
negative regulation of insulin like growth factor receptor signaling pathway
|
GO:0043569 |
4 |
0.884
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.884
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.879
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.877
|
|
|
|
negative regulation of wnt signaling pathway involved in heart development
|
GO:0003308 |
2 |
0.877
|
|
|
|
positive regulation of cardiac muscle cell differentiation
|
GO:2000727 |
4 |
0.876
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.874
|
Human |
|
|
axis elongation
|
GO:0003401 |
4 |
0.870
|
|
|
|
negative regulation of kidney development
|
GO:0090185 |
2 |
0.867
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.866
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.864
|
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.863
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.858
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.857
|
Human |
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.855
|
Fly |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.853
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.852
|
Human |
|
|
wnt signaling pathway involved in heart development
|
GO:0003306 |
5 |
0.848
|
|
|
|
negative regulation of epithelial cell differentiation
|
GO:0030857 |
6 |
0.847
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.846
|
|
|
|
metanephric comma shaped body morphogenesis
|
GO:0072278 |
2 |
0.845
|
|
|
|
lung morphogenesis
|
GO:0060425 |
6 |
0.845
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.843
|
Human |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.841
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.839
|
Fly |
|
|
aldosterone metabolic process
|
GO:0032341 |
9 |
0.838
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.836
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.833
|
Human |
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.827
|
Human |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.825
|
Human |
|
|
c21 steroid hormone metabolic process
|
GO:0008207 |
17 |
0.823
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.823
|
Human |
|
|
dorsal ventral axis specification
|
GO:0009950 |
7 |
0.821
|
Mouse |
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.818
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.815
|
Human |
|
|
heart valve development
|
GO:0003170 |
8 |
0.815
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.813
|
Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.812
|
Worm Fly |
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.812
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.809
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.809
|
Human |
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.809
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.809
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.807
|
Human |
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
3 |
0.802
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.801
|
Mouse Fly |
|
|
regulation of collagen metabolic process
|
GO:0010712 |
15 |
0.798
|
|
|
|
glucocorticoid biosynthetic process
|
GO:0006704 |
8 |
0.798
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.795
|
Human |
|
|
semicircular canal morphogenesis
|
GO:0048752 |
1 |
0.794
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.790
|
Human |
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.790
|
|
|
|
response to bmp
|
GO:0071772 |
8 |
0.789
|
Human |
|
|
cell proliferation involved in heart morphogenesis
|
GO:0061323 |
1 |
0.784
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.783
|
Human Zebrafish |
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.781
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.779
|
|
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
6 |
0.775
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.775
|
Human |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.771
|
|
|
|
heart valve morphogenesis
|
GO:0003179 |
8 |
0.770
|
Human |
|
|
endocrine pancreas development
|
GO:0031018 |
11 |
0.769
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.769
|
|
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
8 |
0.768
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
9 |
0.768
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.762
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.758
|
Human |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.755
|
|
|
|
negative regulation of epidermis development
|
GO:0045683 |
5 |
0.754
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.753
|
|
|
|
negative regulation of aldosterone metabolic process
|
GO:0032345 |
4 |
0.747
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.746
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.742
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.736
|
Human |
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
5 |
0.731
|
Mouse |
|
|
cardiac muscle fiber development
|
GO:0048739 |
4 |
0.730
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.729
|
Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.729
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.723
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.721
|
Human |
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.721
|
|
|
|
regulation of insulin like growth factor receptor signaling pathway
|
GO:0043567 |
8 |
0.720
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.718
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
15 |
0.716
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.716
|
|
|
|
morphogenesis of an endothelium
|
GO:0003159 |
6 |
0.714
|
Human |
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.713
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.713
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.706
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.700
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.697
|
|
|
|
comma shaped body morphogenesis
|
GO:0072049 |
2 |
0.697
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.696
|
|
|
|
p38mapk cascade
|
GO:0038066 |
9 |
0.695
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.694
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.694
|
Human Zebrafish Mouse Fly |
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.694
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.689
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
13 |
0.688
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.688
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.687
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.686
|
Human Mouse |
|
|
type b pancreatic cell differentiation
|
GO:0003309 |
5 |
0.685
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.682
|
Human |
|
|
bone mineralization
|
GO:0030282 |
34 |
0.682
|
|
|
|
pancreas development
|
GO:0031016 |
19 |
0.681
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.676
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.675
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.675
|
Mouse |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.672
|
Human |
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.672
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.671
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.669
|
Human Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.666
|
|
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.666
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.666
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.665
|
Human Zebrafish Mouse |
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.665
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.665
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.665
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.663
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.662
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.661
|
Human Zebrafish |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.660
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.657
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.653
|
Human |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.653
|
|
|
|
glomerulus vasculature development
|
GO:0072012 |
6 |
0.648
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.645
|
Human |
|
|
lung epithelium development
|
GO:0060428 |
7 |
0.642
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
10 |
0.641
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.640
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
10 |
0.637
|
|
|
|
kidney vasculature development
|
GO:0061440 |
7 |
0.636
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.631
|
|
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.629
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.624
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.624
|
Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.624
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.623
|
Human Fly |
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.622
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.622
|
Human Mouse Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.616
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
8 |
0.614
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.613
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.610
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.608
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.607
|
Human |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.606
|
|
|
|
ventricular cardiac muscle cell differentiation
|
GO:0055012 |
1 |
0.605
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.603
|
Human |
|
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.599
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.599
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.598
|
Human |
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.595
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.595
|
Human |
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
12 |
0.592
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.589
|
Human |
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.589
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.586
|
Human |
|
|
endoderm development
|
GO:0007492 |
33 |
0.582
|
Mouse Fly |
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.580
|
Human |
|
|
metanephric nephron development
|
GO:0072210 |
9 |
0.578
|
|
|
|
bone maturation
|
GO:0070977 |
5 |
0.576
|
|
|
|
positive regulation of osteoblast proliferation
|
GO:0033690 |
3 |
0.575
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.572
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.571
|
|
|
|
glucocorticoid metabolic process
|
GO:0008211 |
10 |
0.570
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.570
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.569
|
Human |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.569
|
|
|
|
ossification involved in bone maturation
|
GO:0043931 |
4 |
0.569
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.564
|
Mouse |
|
|
renal tubule development
|
GO:0061326 |
19 |
0.564
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.563
|
|
|
|
semicircular canal formation
|
GO:0060876 |
1 |
0.561
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.559
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.558
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.557
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.555
|
Human |
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.553
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.547
|
|
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
0.545
|
Human |
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.544
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.544
|
Human |
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.543
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.542
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.541
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.541
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.540
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.538
|
Human Zebrafish Mouse Fly |
|
|
cortisol metabolic process
|
GO:0034650 |
8 |
0.534
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.534
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.533
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.532
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
6 |
0.530
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.530
|
Human Worm Fly |
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.530
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.529
|
Mouse Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.527
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.526
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.517
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.516
|
Human |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.514
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.512
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.511
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.510
|
Human |
|
|
dna replication
|
GO:0006260 |
116 |
0.509
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.507
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.506
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.506
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.504
|
|
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.504
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.493
|
|
|
|
semicircular canal development
|
GO:0060872 |
1 |
0.492
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.491
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.489
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.489
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.487
|
Mouse |
|
|
epithelial cell morphogenesis
|
GO:0003382 |
8 |
0.487
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.484
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.483
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.478
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.478
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.477
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.477
|
Human |
|
|
negative regulation of thymocyte apoptotic process
|
GO:0070244 |
1 |
0.476
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.473
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.472
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.472
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.470
|
Human |
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.470
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.469
|
Mouse |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.468
|
Human |
|
|
regulation of collagen biosynthetic process
|
GO:0032965 |
11 |
0.467
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.467
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.464
|
Worm |
|
|
mesenchymal cell proliferation
|
GO:0010463 |
7 |
0.463
|
Mouse |
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
0.462
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
7 |
0.460
|
Fly |
|
|
glomerulus development
|
GO:0032835 |
15 |
0.460
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.458
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.455
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.454
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.451
|
Mouse Fly |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.450
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.448
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
75 |
0.448
|
Mouse Fly |
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.440
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.440
|
Human |
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.439
|
Human |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.438
|
Mouse |
|
|
regulation of cell proliferation involved in heart morphogenesis
|
GO:2000136 |
1 |
0.438
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
11 |
0.436
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.436
|
Fly |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.434
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
11 |
0.433
|
Zebrafish |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.432
|
Human Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.431
|
Mouse Worm |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.427
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.426
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.425
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.423
|
Human Zebrafish |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.417
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.416
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.415
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.414
|
|
|
|
regulation of branch elongation involved in ureteric bud branching
|
GO:0072095 |
1 |
0.414
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.412
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.411
|
Human Worm Fly |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.409
|
Human |
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.409
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
12 |
0.407
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.405
|
Human Mouse |
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.403
|
Fly |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.401
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.398
|
Human Mouse Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.398
|
Human |
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.396
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.395
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.393
|
Human |
|
|
negative regulation of steroid metabolic process
|
GO:0045939 |
15 |
0.392
|
|
|
|
mesenchymal to epithelial transition
|
GO:0060231 |
6 |
0.392
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.387
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.387
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.385
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.385
|
Human |
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.384
|
Human |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.382
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.381
|
Human Worm Fly |
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.377
|
Human |
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.377
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.376
|
Fly |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.375
|
Human |
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
5 |
0.375
|
Fly |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.374
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.374
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.372
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.370
|
Human |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.369
|
Human Mouse |
|
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.369
|
|
|
|
nephron tubule development
|
GO:0072080 |
17 |
0.369
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.369
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.368
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.367
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.367
|
|
|
|
regulation of gastrulation
|
GO:0010470 |
12 |
0.365
|
Mouse |
|
|
immature t cell proliferation
|
GO:0033079 |
1 |
0.365
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.362
|
Human Mouse |
|
|
forebrain development
|
GO:0030900 |
26 |
0.357
|
Mouse |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.357
|
|
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
3 |
0.353
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.352
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.352
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.351
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.350
|
Human Worm Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.350
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.350
|
Human |
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.349
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.349
|
Human Mouse |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.348
|
Human |
|
|
osteoblast proliferation
|
GO:0033687 |
8 |
0.347
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.347
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.345
|
Human Zebrafish Mouse Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.344
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.343
|
Human |
|
|
renal tubule morphogenesis
|
GO:0061333 |
14 |
0.338
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.337
|
Human Mouse |
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.336
|
Human Zebrafish |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.335
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.334
|
|
|
|
artery morphogenesis
|
GO:0048844 |
7 |
0.334
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.334
|
Human |
|
|
kidney development
|
GO:0001822 |
53 |
0.332
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.331
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.331
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.331
|
Human Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.330
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.329
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.328
|
|
|
|
regulation of calcium independent cell cell adhesion
|
GO:0051040 |
2 |
0.327
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.325
|
|
|
|
regulation of kidney development
|
GO:0090183 |
10 |
0.323
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.323
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.321
|
Human |
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.321
|
|
|
|
regulation of glucocorticoid biosynthetic process
|
GO:0031946 |
5 |
0.319
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.317
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.315
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.314
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.313
|
|
|
|
regulation of skeletal muscle tissue development
|
GO:0048641 |
15 |
0.311
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.308
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.308
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.308
|
Human |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.303
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.302
|
Fly |
|
|
monocyte differentiation
|
GO:0030224 |
15 |
0.302
|
|
|
|
negative regulation of t cell differentiation in thymus
|
GO:0033085 |
2 |
0.301
|
|
|
|
regulation of steroid hormone biosynthetic process
|
GO:0090030 |
6 |
0.300
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.300
|
|
