|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
1.000
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.999
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.999
|
|
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
1 |
0.998
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.997
|
|
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.996
|
|
|
|
mitral valve development
|
GO:0003174 |
3 |
0.995
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.994
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.994
|
|
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.989
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.987
|
Mouse |
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
0.986
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.984
|
|
|
|
endocardial cushion cell fate commitment
|
GO:0061445 |
1 |
0.982
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.976
|
|
|
|
positive regulation of bone mineralization
|
GO:0030501 |
19 |
0.976
|
|
|
|
septum primum development
|
GO:0003284 |
1 |
0.973
|
|
|
|
atrial septum morphogenesis
|
GO:0060413 |
5 |
0.972
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.964
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.961
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.961
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.960
|
|
|
|
positive regulation of trophoblast cell migration
|
GO:1901165 |
2 |
0.960
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.956
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.952
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.952
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.948
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.935
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.935
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.932
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.932
|
|
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
7 |
0.931
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.928
|
|
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.926
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.917
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.917
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.913
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.909
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.908
|
|
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.903
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.902
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.901
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.898
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.896
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.893
|
|
|
|
response to cholesterol
|
GO:0070723 |
11 |
0.888
|
|
|
|
atrial septum development
|
GO:0003283 |
8 |
0.881
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.877
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.876
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.876
|
|
|
|
maintenance of protein location in nucleus
|
GO:0051457 |
12 |
0.863
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.852
|
|
|
|
endocardial cell fate commitment
|
GO:0060957 |
1 |
0.847
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.846
|
|
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.843
|
|
|
|
cardiac atrium development
|
GO:0003230 |
10 |
0.840
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.821
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.820
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.810
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.808
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.807
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.805
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.794
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.793
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.792
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.789
|
Mouse |
|
|
blood circulation
|
GO:0008015 |
113 |
0.780
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.778
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.770
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.769
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.763
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.754
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.751
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.740
|
|
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.736
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.734
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.733
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.730
|
|
|
|
response to sterol
|
GO:0036314 |
14 |
0.723
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.722
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.720
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.715
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.714
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.709
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.709
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.708
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.706
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.701
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.701
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.699
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.699
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.691
|
|
|
|
maintenance of protein localization in organelle
|
GO:0072595 |
15 |
0.690
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.682
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.680
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.676
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
14 |
0.673
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.663
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.661
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.654
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.647
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.647
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.643
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.638
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.635
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.623
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.622
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.622
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.622
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.622
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.621
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.612
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.607
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.607
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.604
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.602
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.600
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.598
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.594
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.588
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.587
|
Human Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.587
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.587
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.586
|
|
|
|
negative regulation of adherens junction organization
|
GO:1903392 |
5 |
0.585
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.583
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.578
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.578
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.578
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.575
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.575
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.574
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.566
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.562
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.560
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.556
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.554
|
|
|
|
heart valve development
|
GO:0003170 |
8 |
0.547
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.546
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.545
|
Human |
|
|
response to starvation
|
GO:0042594 |
59 |
0.544
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.543
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.541
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.537
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.532
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.530
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.530
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.529
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.526
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.519
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.518
|
Mouse |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.515
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.514
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.511
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.508
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.505
|
Human |
|
|
response to radiation
|
GO:0009314 |
151 |
0.504
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.503
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.500
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.497
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.493
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.493
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.490
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.489
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.485
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.483
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.481
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.481
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.476
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.475
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.475
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.472
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.472
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.470
|
Mouse |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.470
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.469
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.469
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.468
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.467
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.464
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.456
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.451
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.451
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.448
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.439
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.439
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.439
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.436
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.430
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.426
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.423
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.416
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.414
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.413
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.413
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.410
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.408
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.403
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.403
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.403
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.403
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.402
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.402
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.401
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.401
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.401
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.400
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.397
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.397
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.393
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.391
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.391
|
Mouse |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.390
|
Mouse |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.387
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.387
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.386
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.385
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.381
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.379
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
75 |
0.379
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.377
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.373
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.368
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.366
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.360
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.358
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.357
|
Human Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.356
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.356
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.355
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.355
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.355
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.352
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.352
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.350
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.349
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.343
|
Mouse |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.342
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.338
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.337
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.336
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.332
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.332
|
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.330
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.329
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.328
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.328
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.328
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.326
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.326
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.326
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.324
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.324
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.323
|
Mouse |
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.322
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.320
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.319
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.318
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.317
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.317
|
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.316
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.316
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.313
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.312
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.311
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.309
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.309
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.307
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.303
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.302
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.302
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.302
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.299
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
9 |
0.298
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.298
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.298
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.297
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.296
|
|
|
|
negative regulation of activin receptor signaling pathway
|
GO:0032926 |
6 |
0.296
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.294
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.293
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.291
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.290
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.289
|
|
|
|
nodal signaling pathway
|
GO:0038092 |
5 |
0.289
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.286
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.284
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.283
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.280
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.279
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.278
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.277
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.277
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.274
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.273
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.272
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.268
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.267
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.267
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.264
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.264
|
|
|
|
heart valve morphogenesis
|
GO:0003179 |
8 |
0.263
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.262
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.261
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.261
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.260
|
Mouse |
|
|
endoderm development
|
GO:0007492 |
33 |
0.259
|
|
|
|
wound healing spreading of epidermal cells
|
GO:0035313 |
6 |
0.258
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.257
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.257
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.256
|
|
|
|
lymphatic endothelial cell differentiation
|
GO:0060836 |
3 |
0.256
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.251
|
|
|
|
system process
|
GO:0003008 |
349 |
0.251
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
261 |
0.250
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.249
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.248
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.239
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.238
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.238
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.235
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.234
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.234
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.233
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.233
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.231
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.231
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.231
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.227
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.227
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.226
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.226
|
|
|
|
negative regulation of focal adhesion assembly
|
GO:0051895 |
5 |
0.225
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.223
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.221
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.221
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.221
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.219
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.218
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.218
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.218
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.217
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.215
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.214
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.213
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.212
|
|
|
|
head development
|
GO:0060322 |
108 |
0.211
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.210
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.209
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.208
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.207
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.205
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.202
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.201
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.201
|
|
|
|
growth
|
GO:0040007 |
202 |
0.198
|
|
|
|
morphogenesis of an endothelium
|
GO:0003159 |
6 |
0.196
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.195
|
Human Mouse |
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.194
|
|
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.193
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.188
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.188
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.187
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.187
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.187
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.186
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.185
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.184
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.184
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.184
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.183
|
|
|
|
negative regulation of endothelial cell differentiation
|
GO:0045602 |
2 |
0.183
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.182
|
Mouse |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.181
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.181
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.180
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.179
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.177
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.176
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.176
|
|
|
|
molting cycle process
|
GO:0022404 |
12 |
0.175
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.175
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.174
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.173
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.170
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.170
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.169
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.168
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.164
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.164
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.162
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.161
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.159
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.158
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.156
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.155
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.151
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.149
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.144
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.142
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.142
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.141
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.140
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.139
|
Human Mouse |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.137
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.135
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.135
|
|
|
|
positive regulation of activin receptor signaling pathway
|
GO:0032927 |
6 |
0.133
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.129
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.129
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.129
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.128
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.128
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.127
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.125
|
Human Mouse |
|
|
response to uv
|
GO:0009411 |
73 |
0.125
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.125
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.123
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.123
|
|
|
|
female pregnancy
|
GO:0007565 |
17 |
0.122
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.122
|
|
|
|
molting cycle
|
GO:0042303 |
28 |
0.121
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.121
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.120
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.119
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.117
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.115
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.114
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.114
|
|
|
|
limb development
|
GO:0060173 |
23 |
0.114
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.114
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.113
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.113
|
|
|
|
aging
|
GO:0007568 |
66 |
0.112
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.111
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.111
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.110
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.110
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.110
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.108
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.107
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.107
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.106
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.104
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.103
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.103
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.101
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.101
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.101
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.100
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.099
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.099
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.099
|
Mouse |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.099
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.098
|
Human Mouse |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.098
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.098
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.097
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.097
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.097
|
Human Mouse |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.097
|
Human Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.096
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.095
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.095
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.094
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.094
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.094
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.093
|
Mouse |
|
|
regulation of dna biosynthetic process
|
GO:2000278 |
18 |
0.091
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.091
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.086
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.086
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.084
|
Human Mouse |
|
|
epiboly
|
GO:0090504 |
9 |
0.084
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.084
|
|
|
|
lymph vessel development
|
GO:0001945 |
9 |
0.084
|
|
|
|
limb morphogenesis
|
GO:0035108 |
16 |
0.084
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.083
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.083
|
|
|
|
hair follicle development
|
GO:0001942 |
11 |
0.082
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.082
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.080
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.080
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.080
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.080
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.079
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.079
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.079
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.079
|
Human Mouse |
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.077
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.077
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.077
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.076
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.076
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.075
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.075
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.075
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.075
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.074
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.074
|
|