Homo sapiens

56 known processes

CHCHD4

coiled-coil-helix-coiled-coil-helix domain containing 4

(Aliases: TIMM40,MIA40,FLJ31709)

CHCHD4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 156 0.441
post embryonic development GO:0009791 2 0.319
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.149
nadh dehydrogenase complex assembly GO:0010257 16 0.124
single organism membrane organization GO:0044802 268 0.096
vesicle mediated transport GO:0016192 371 0.085
determination of adult lifespan GO:0008340 2 0.057
immune response GO:0006955 307 0.040
actin filament based process GO:0030029 224 0.040
multicellular organismal aging GO:0010259 3 0.039
cellular amino acid metabolic process GO:0006520 116 0.038
single organism cellular localization GO:1902580 332 0.038
negative regulation of protein metabolic process GO:0051248 391 0.038
neuromuscular junction development GO:0007528 3 0.036
endocytosis GO:0006897 159 0.035
cytoplasmic transport GO:0016482 379 0.035
positive regulation of programmed cell death GO:0043068 249 0.035
mitochondrial respiratory chain complex assembly GO:0033108 23 0.035
protein localization to organelle GO:0033365 280 0.034
positive regulation of hydrolase activity GO:0051345 331 0.032
negative regulation of catalytic activity GO:0043086 335 0.031
defense response GO:0006952 315 0.030
response to external biotic stimulus GO:0043207 261 0.030
growth GO:0040007 202 0.030
intracellular protein transport GO:0006886 270 0.029
positive regulation of cell death GO:0010942 263 0.029
regulation of defense response GO:0031347 154 0.029
regulation of peptidase activity GO:0052547 180 0.029
cellular ketone metabolic process GO:0042180 80 0.029
cellular protein complex assembly GO:0043623 188 0.028
protein maturation GO:0051604 233 0.028
positive regulation of developmental process GO:0051094 314 0.028
sulfur compound metabolic process GO:0006790 101 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
intracellular protein transmembrane transport GO:0065002 24 0.027
positive regulation of apoptotic process GO:0043065 246 0.026
monocarboxylic acid metabolic process GO:0032787 185 0.026
innate immune response GO:0045087 178 0.026
posttranscriptional regulation of gene expression GO:0010608 213 0.025
positive regulation of nucleoside metabolic process GO:0045979 186 0.025
coenzyme metabolic process GO:0006732 65 0.025
protein localization to mitochondrion GO:0070585 25 0.025
negative regulation of immune system process GO:0002683 136 0.024
regulation of proteolysis GO:0030162 293 0.024
protein localization to membrane GO:0072657 160 0.024
protein import GO:0017038 130 0.024
response to other organism GO:0051707 261 0.023
respiratory chain complex iv assembly GO:0008535 9 0.023
receptor mediated endocytosis GO:0006898 84 0.023
embryo development GO:0009790 123 0.023
negative regulation of peptidase activity GO:0010466 91 0.022
dephosphorylation GO:0016311 209 0.022
negative regulation of protein modification process GO:0031400 200 0.021
transmembrane transport GO:0055085 399 0.021
membrane organization GO:0061024 292 0.020
regulation of protein maturation GO:1903317 150 0.020
negative regulation of organelle organization GO:0010639 126 0.020
negative regulation of cell death GO:0060548 345 0.020
regulation of cysteine type endopeptidase activity GO:2000116 127 0.020
regulation of protein kinase activity GO:0045859 289 0.020
regulation of immune response GO:0050776 201 0.020
negative regulation of protein maturation GO:1903318 142 0.019
chemical homeostasis GO:0048878 306 0.019
positive regulation of catabolic process GO:0009896 310 0.019
muscle system process GO:0003012 81 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
regulation of innate immune response GO:0045088 97 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
glycerol metabolic process GO:0006071 4 0.018
protein processing GO:0016485 226 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
protein ubiquitination GO:0016567 314 0.018
nerve development GO:0021675 4 0.018
cellular lipid metabolic process GO:0044255 303 0.018
regulation of kinase activity GO:0043549 314 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
oogenesis GO:0048477 2 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
mitochondrial transport GO:0006839 60 0.017
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.016
lipid metabolic process GO:0006629 381 0.016
response to abiotic stimulus GO:0009628 336 0.016
cofactor metabolic process GO:0051186 87 0.016
system process GO:0003008 349 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
apoptotic signaling pathway GO:0097190 268 0.016
negative regulation of protein processing GO:0010955 142 0.016
ion homeostasis GO:0050801 230 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.015
protein targeting GO:0006605 187 0.015
cellular protein catabolic process GO:0044257 261 0.015
defense response to other organism GO:0098542 129 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
regulation of protein processing GO:0070613 150 0.015
regulation of growth GO:0040008 165 0.015
cellular chemical homeostasis GO:0055082 180 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
carboxylic acid biosynthetic process GO:0046394 97 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
cellular cation homeostasis GO:0030003 163 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.015
mitochondrial respiratory chain complex i assembly GO:0032981 16 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
amine metabolic process GO:0009308 44 0.014
protein targeting to mitochondrion GO:0006626 19 0.014
regulation of cell cycle GO:0051726 393 0.014
locomotory behavior GO:0007626 1 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
cellular ion homeostasis GO:0006873 168 0.013
adult locomotory behavior GO:0008344 1 0.013
regulation of ion transport GO:0043269 189 0.013
carbohydrate metabolic process GO:0005975 207 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
response to biotic stimulus GO:0009607 276 0.013
rna interference GO:0016246 4 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
cation homeostasis GO:0055080 189 0.013
positive regulation of peptidase activity GO:0010952 88 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
positive regulation of transport GO:0051050 336 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
regulation of protein localization GO:0032880 296 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
negative regulation of proteolysis GO:0045861 132 0.012
protein catabolic process GO:0030163 325 0.012
metal ion transport GO:0030001 272 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.012
single organism reproductive process GO:0044702 98 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
maintenance of location GO:0051235 112 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
small molecule biosynthetic process GO:0044283 157 0.011
hindbrain development GO:0030902 3 0.011
negative regulation of muscle hypertrophy GO:0014741 3 0.011
cofactor biosynthetic process GO:0051188 31 0.011
cytokine mediated signaling pathway GO:0019221 109 0.011
biological adhesion GO:0022610 331 0.011
organophosphate catabolic process GO:0046434 430 0.011
mitotic cell cycle process GO:1903047 286 0.011
segmentation GO:0035282 4 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
cardiovascular system development GO:0072358 262 0.011
positive regulation of cell motility GO:2000147 177 0.011
microtubule based process GO:0007017 210 0.011
regulation of cellular amine metabolic process GO:0033238 11 0.011
mitochondrial membrane organization GO:0007006 40 0.011
negative regulation of transferase activity GO:0051348 124 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
nucleoside phosphate catabolic process GO:1901292 412 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
zymogen activation GO:0031638 70 0.011
organelle fission GO:0048285 149 0.011
neurogenesis GO:0022008 169 0.010
epithelium development GO:0060429 227 0.010
trna metabolic process GO:0006399 35 0.010
regulation of cell motility GO:2000145 299 0.010
cell adhesion GO:0007155 325 0.010
female gamete generation GO:0007292 2 0.010
response to cytokine GO:0034097 232 0.010
negative regulation of endopeptidase activity GO:0010951 84 0.010
gtp metabolic process GO:0046039 239 0.010
central nervous system development GO:0007417 123 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
single organism membrane fusion GO:0044801 37 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010

CHCHD4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.033
inherited metabolic disorder DOID:655 242 0.033
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015