Homo sapiens

62 known processes

PSMF1

proteasome (prosome, macropain) inhibitor subunit 1 (PI31)

(Aliases: PI31)

PSMF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 175 0.273
rna splicing GO:0008380 131 0.170
epidermis morphogenesis GO:0048730 3 0.109
gabaergic neuron differentiation GO:0097154 1 0.102
mrna splicing via spliceosome GO:0000398 89 0.094
rna processing GO:0006396 255 0.091
protein modification by small protein conjugation GO:0032446 342 0.085
mrna processing GO:0006397 133 0.083
modification dependent macromolecule catabolic process GO:0043632 212 0.083
motor neuron axon guidance GO:0008045 2 0.082
sex determination GO:0007530 3 0.082
single organism cellular localization GO:1902580 332 0.079
oogenesis GO:0048477 2 0.079
vesicle mediated transport GO:0016192 371 0.071
ubiquitin dependent protein catabolic process GO:0006511 206 0.070
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.067
post embryonic development GO:0009791 2 0.066
negative regulation of phosphate metabolic process GO:0045936 267 0.064
mating GO:0007618 1 0.061
regulation of establishment of protein localization GO:0070201 242 0.061
autophagy GO:0006914 88 0.058
biological adhesion GO:0022610 331 0.056
cell morphogenesis GO:0000902 296 0.054
regulation of cellular amino acid metabolic process GO:0006521 6 0.052
mitotic cell cycle GO:0000278 326 0.051
oxidation reduction process GO:0055114 396 0.049
protein localization to organelle GO:0033365 280 0.048
regulation of cellular amine metabolic process GO:0033238 11 0.047
cellular protein catabolic process GO:0044257 261 0.047
negative regulation of protein metabolic process GO:0051248 391 0.046
cellular amino acid metabolic process GO:0006520 116 0.045
cellular component morphogenesis GO:0032989 314 0.045
cell projection morphogenesis GO:0048858 129 0.043
mitotic cell cycle process GO:1903047 286 0.040
single organism carbohydrate metabolic process GO:0044723 193 0.039
negative regulation of phosphorus metabolic process GO:0010563 267 0.038
apoptotic signaling pathway GO:0097190 268 0.038
positive regulation of transport GO:0051050 336 0.037
amine metabolic process GO:0009308 44 0.037
hemopoiesis GO:0030097 180 0.037
cell development GO:0048468 328 0.036
hindbrain development GO:0030902 3 0.035
glycoprotein metabolic process GO:0009100 110 0.034
endocytosis GO:0006897 159 0.034
nervous system development GO:0007399 293 0.034
cellular response to dna damage stimulus GO:0006974 379 0.034
protein ubiquitination GO:0016567 314 0.034
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.033
regulation of protein kinase activity GO:0045859 289 0.033
female gamete generation GO:0007292 2 0.033
cell fate commitment involved in pattern specification GO:0060581 1 0.032
intracellular protein transport GO:0006886 270 0.032
nitrogen compound transport GO:0071705 191 0.032
cytoplasmic transport GO:0016482 379 0.032
enzyme linked receptor protein signaling pathway GO:0007167 303 0.031
negative regulation of catalytic activity GO:0043086 335 0.031
regulation of cell differentiation GO:0045595 393 0.030
rna splicing via transesterification reactions GO:0000375 90 0.030
regulation of kinase activity GO:0043549 314 0.029
cellular amine metabolic process GO:0044106 41 0.029
regulation of transferase activity GO:0051338 355 0.029
cellular component assembly involved in morphogenesis GO:0010927 73 0.029
spermatid differentiation GO:0048515 4 0.029
protein catabolic process GO:0030163 325 0.028
negative regulation of developmental process GO:0051093 247 0.028
endosomal transport GO:0016197 129 0.028
methylation GO:0032259 106 0.027
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.027
intracellular receptor signaling pathway GO:0030522 104 0.027
immune system development GO:0002520 195 0.027
limbic system development GO:0021761 3 0.027
single organism membrane fusion GO:0044801 37 0.027
cilium organization GO:0044782 68 0.026
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.026
inner ear morphogenesis GO:0042472 4 0.025
protein targeting GO:0006605 187 0.025
negative regulation of protein maturation GO:1903318 142 0.025
endodermal cell fate specification GO:0001714 4 0.025
regulation of protein serine threonine kinase activity GO:0071900 179 0.025
negative regulation of protein modification process GO:0031400 200 0.025
neuromuscular junction development GO:0007528 3 0.025
regulation of mrna metabolic process GO:1903311 53 0.024
negative regulation of cell fate specification GO:0009996 3 0.024
response to abiotic stimulus GO:0009628 336 0.024
hematopoietic or lymphoid organ development GO:0048534 186 0.024
regulation of protein localization GO:0032880 296 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.024
epithelial cell differentiation GO:0030855 141 0.023
positive regulation of developmental process GO:0051094 314 0.023
cell part morphogenesis GO:0032990 137 0.023
regulation of cell cycle process GO:0010564 266 0.023
negative regulation of protein phosphorylation GO:0001933 140 0.023
oocyte development GO:0048599 1 0.023
regulation of protein transport GO:0051223 213 0.023
neural crest cell development GO:0014032 3 0.022
positive regulation of map kinase activity GO:0043406 80 0.022
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.022
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
organ formation GO:0048645 3 0.021
microtubule based process GO:0007017 210 0.020
vasodilation GO:0042311 4 0.020
axoneme assembly GO:0035082 3 0.020
embryonic epithelial tube formation GO:0001838 4 0.020
secretion GO:0046903 254 0.020
mitochondrion organization GO:0007005 156 0.020
establishment or maintenance of monopolar cell polarity GO:0061339 1 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
locomotory behavior GO:0007626 1 0.020
regulation of mrna splicing via spliceosome GO:0048024 32 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
regulation of protein processing GO:0070613 150 0.020
negative regulation of transferase activity GO:0051348 124 0.019
cell adhesion GO:0007155 325 0.019
negative regulation of cell fate commitment GO:0010454 3 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
regulation of intracellular transport GO:0032386 195 0.019
single organism cell adhesion GO:0098602 179 0.019
establishment of planar polarity GO:0001736 3 0.019
regulation of mesonephros development GO:0061217 3 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
cell fate determination GO:0001709 3 0.018
spliceosomal snrnp assembly GO:0000387 28 0.018
regulation of mitotic cell cycle GO:0007346 189 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
reproductive process GO:0022414 106 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
negative regulation of cell cycle GO:0045786 193 0.018
organelle assembly GO:0070925 176 0.018
spermatid development GO:0007286 4 0.018
dna repair GO:0006281 198 0.018
muscle cell fate commitment GO:0042693 4 0.017
cytokine production GO:0001816 247 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
cellular lipid metabolic process GO:0044255 303 0.017
cilium morphogenesis GO:0060271 75 0.017
organelle localization GO:0051640 84 0.017
cellular ketone metabolic process GO:0042180 80 0.017
secretion by cell GO:0032940 226 0.017
dosage compensation GO:0007549 3 0.017
regulation of translation GO:0006417 89 0.017
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.017
axis elongation GO:0003401 4 0.017
negative regulation of kinase activity GO:0033673 106 0.017
lipid catabolic process GO:0016042 84 0.016
morphogenesis of a polarized epithelium GO:0001738 3 0.016
negative regulation of protein processing GO:0010955 142 0.016
protein maturation GO:0051604 233 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
basement membrane organization GO:0071711 3 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
mitochondrial transport GO:0006839 60 0.016
epithelium development GO:0060429 227 0.016
neural tube formation GO:0001841 3 0.016
histone modification GO:0016570 251 0.016
regulation of mrna processing GO:0050684 48 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
wnt signaling pathway GO:0016055 156 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
negative regulation of immune system process GO:0002683 136 0.015
negative regulation of catabolic process GO:0009895 104 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
regulation of mapk cascade GO:0043408 262 0.015
regulation of secretion GO:0051046 194 0.015
organ induction GO:0001759 4 0.015
rna interference GO:0016246 4 0.015
regulation of protein catabolic process GO:0042176 155 0.015
cell substrate adhesion GO:0031589 132 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
lipid metabolic process GO:0006629 381 0.015
cochlea morphogenesis GO:0090103 1 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
positive regulation of synaptic transmission GO:0050806 4 0.014
dephosphorylation GO:0016311 209 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
glial cell migration GO:0008347 4 0.014
regulation of cardioblast differentiation GO:0051890 4 0.014
positive regulation of catabolic process GO:0009896 310 0.014
regulation of heart morphogenesis GO:2000826 4 0.014
positive regulation of intracellular transport GO:0032388 104 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
nucleobase containing compound transport GO:0015931 51 0.014
response to hypoxia GO:0001666 96 0.014
regulation of definitive erythrocyte differentiation GO:0010724 2 0.014
response to wounding GO:0009611 168 0.014
heart formation GO:0060914 2 0.014
brain development GO:0007420 97 0.014
lymphocyte activation GO:0046649 133 0.014
cell projection organization GO:0030030 252 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
ribonucleoprotein complex subunit organization GO:0071826 81 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
neural crest cell migration GO:0001755 2 0.013
positive regulation of mesonephros development GO:0061213 2 0.013
developmental process involved in reproduction GO:0003006 66 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
neurotransmitter secretion GO:0007269 4 0.013
protein monoubiquitination GO:0006513 39 0.013
circulatory system process GO:0003013 113 0.013
tube closure GO:0060606 3 0.013
cellular response to oxidative stress GO:0034599 85 0.013
response to endoplasmic reticulum stress GO:0034976 49 0.013
cardiac cell fate specification GO:0060912 1 0.013
positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 11 0.013
regeneration GO:0031099 4 0.013
actin cytoskeleton organization GO:0030036 207 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
positive regulation of nucleobase containing compound transport GO:0032241 1 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.013
regulation of rna splicing GO:0043484 62 0.013
organ morphogenesis GO:0009887 147 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
compound eye development GO:0048749 1 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
cell projection assembly GO:0030031 126 0.013
chromatin modification GO:0016568 298 0.013
oocyte differentiation GO:0009994 2 0.013
regulation of cell cycle GO:0051726 393 0.013
retinal ganglion cell axon guidance GO:0031290 2 0.013
neuron development GO:0048666 113 0.013
nerve development GO:0021675 4 0.012
system process GO:0003008 349 0.012
cofactor metabolic process GO:0051186 87 0.012
single organism reproductive process GO:0044702 98 0.012
primary neural tube formation GO:0014020 3 0.012
regulation of heart induction GO:0090381 2 0.012
nuclear transport GO:0051169 179 0.012
specification of organ identity GO:0010092 3 0.012
actin filament based process GO:0030029 224 0.012
heart induction GO:0003129 4 0.012
heart field specification GO:0003128 2 0.012
nucleotide catabolic process GO:0009166 408 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
interleukin 8 production GO:0032637 51 0.012
regulation of cell development GO:0060284 161 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
ossification GO:0001503 121 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
neurological system process GO:0050877 163 0.012
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
cellular response to extracellular stimulus GO:0031668 72 0.011
purine containing compound catabolic process GO:0072523 411 0.011
cell cycle phase transition GO:0044770 173 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
endodermal cell fate commitment GO:0001711 4 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.011
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
establishment of protein localization to mitochondrion GO:0072655 22 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
generation of neurons GO:0048699 152 0.011
central nervous system development GO:0007417 123 0.011
protein localization to membrane GO:0072657 160 0.011
regulation of organ formation GO:0003156 4 0.011
protein localization to mitochondrion GO:0070585 25 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
double strand break repair GO:0006302 101 0.011
regulation of locomotion GO:0040012 329 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
carbohydrate catabolic process GO:0016052 36 0.011
establishment of tissue polarity GO:0007164 3 0.011
adult locomotory behavior GO:0008344 1 0.011
neuron differentiation GO:0030182 138 0.011
behavior GO:0007610 112 0.011
positive regulation of protein transport GO:0051222 135 0.011
neuroblast proliferation GO:0007405 4 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
chemical homeostasis GO:0048878 306 0.011
nucleoside phosphate catabolic process GO:1901292 412 0.011
myeloid cell differentiation GO:0030099 117 0.011
response to external biotic stimulus GO:0043207 261 0.011
atp catabolic process GO:0006200 157 0.011
regulation of autophagy GO:0010506 52 0.011
macromolecule glycosylation GO:0043413 63 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
positive regulation of interleukin 8 production GO:0032757 36 0.011
nuclear export GO:0051168 69 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
chromatin organization GO:0006325 351 0.011
cardioblast cell fate commitment GO:0042684 1 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
rhythmic behavior GO:0007622 2 0.010
erbb signaling pathway GO:0038127 44 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
single organism membrane organization GO:0044802 268 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.010
regulation of binding GO:0051098 111 0.010
positive regulation of chondrocyte differentiation GO:0032332 4 0.010
muscle structure development GO:0061061 98 0.010
cilium assembly GO:0042384 63 0.010
membrane fusion GO:0061025 43 0.010
cochlea development GO:0090102 1 0.010
regulation of map kinase activity GO:0043405 108 0.010
multicellular organismal aging GO:0010259 3 0.010
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
covalent chromatin modification GO:0016569 254 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010

PSMF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.083
nervous system disease DOID:863 431 0.083
sensory system disease DOID:0050155 203 0.074
eye and adnexa disease DOID:1492 150 0.074
retinal disease DOID:5679 118 0.052
eye disease DOID:5614 149 0.052
neurodegenerative disease DOID:1289 102 0.041
parkinson s disease DOID:14330 18 0.028
synucleinopathy DOID:0050890 22 0.028
retinal degeneration DOID:8466 89 0.021
retinitis pigmentosa DOID:10584 51 0.021
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
bone disease DOID:0080001 88 0.017
musculoskeletal system disease DOID:17 223 0.017
connective tissue disease DOID:65 109 0.017
disease of metabolism DOID:0014667 295 0.016
inherited metabolic disorder DOID:655 242 0.013
organ system cancer DOID:0050686 164 0.011
muscular disease DOID:0080000 114 0.010
muscle tissue disease DOID:66 113 0.010