Homo sapiens

49 known processes

PAIP2

poly(A) binding protein interacting protein 2

(Aliases: MGC72018,PAIP2A)

PAIP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 380 0.630
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.575
translation GO:0006412 132 0.534
mrna 3 end processing GO:0031124 24 0.500
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.225
cellular protein catabolic process GO:0044257 261 0.215
post embryonic development GO:0009791 2 0.200
modification dependent macromolecule catabolic process GO:0043632 212 0.198
positive regulation of cellular component organization GO:0051130 376 0.174
negative regulation of protein metabolic process GO:0051248 391 0.169
positive regulation of organelle organization GO:0010638 195 0.158
mrna catabolic process GO:0006402 56 0.150
rna 3 end processing GO:0031123 35 0.145
regulation of translation GO:0006417 89 0.131
positive regulation of cellular catabolic process GO:0031331 284 0.124
positive regulation of catabolic process GO:0009896 310 0.122
posttranscriptional regulation of gene expression GO:0010608 213 0.119
protein catabolic process GO:0030163 325 0.116
rna processing GO:0006396 255 0.106
positive regulation of cellular component biogenesis GO:0044089 158 0.099
rna catabolic process GO:0006401 71 0.098
nuclear transcribed mrna catabolic process GO:0000956 48 0.097
cellular response to dna damage stimulus GO:0006974 379 0.093
dna repair GO:0006281 198 0.087
purine nucleoside catabolic process GO:0006152 398 0.087
proteasomal protein catabolic process GO:0010498 176 0.082
cellular component disassembly GO:0022411 92 0.076
mrna metabolic process GO:0016071 175 0.076
positive regulation of translation GO:0045727 35 0.076
intracellular protein transport GO:0006886 270 0.075
negative regulation of cellular component organization GO:0051129 235 0.074
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.074
purine containing compound catabolic process GO:0072523 411 0.073
regulation of cellular component movement GO:0051270 334 0.071
ribonucleoprotein complex assembly GO:0022618 78 0.071
negative regulation of cellular protein metabolic process GO:0032269 353 0.071
negative regulation of protein modification process GO:0031400 200 0.070
meiosis i GO:0007127 4 0.068
organelle assembly GO:0070925 176 0.064
regulation of chromatin organization GO:1902275 56 0.063
negative regulation of rna catabolic process GO:1902369 4 0.062
ribonucleoprotein complex biogenesis GO:0022613 116 0.062
negative regulation of phosphate metabolic process GO:0045936 267 0.058
protein targeting GO:0006605 187 0.057
negative regulation of protein k63 linked ubiquitination GO:1900045 4 0.057
double strand break repair GO:0006302 101 0.056
positive regulation of protein transport GO:0051222 135 0.056
regulation of cellular amino acid metabolic process GO:0006521 6 0.055
negative regulation of catabolic process GO:0009895 104 0.055
regulation of protein polyubiquitination GO:1902914 8 0.054
negative regulation of protein polyubiquitination GO:1902915 4 0.053
regulation of mrna processing GO:0050684 48 0.052
positive regulation of cell cycle GO:0045787 140 0.052
regulation of proteolysis GO:0030162 293 0.052
regulation of histone modification GO:0031056 47 0.050
positive regulation of cell proliferation GO:0008284 301 0.049
female gamete generation GO:0007292 2 0.049
wnt signaling pathway GO:0016055 156 0.048
regulation of meiosis GO:0040020 3 0.048
glycosyl compound catabolic process GO:1901658 413 0.048
cell division GO:0051301 168 0.047
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.046
regulation of wnt signaling pathway GO:0030111 123 0.046
cellular macromolecular complex assembly GO:0034622 324 0.045
ubiquitin dependent protein catabolic process GO:0006511 206 0.045
negative regulation of mrna catabolic process GO:1902373 4 0.045
single organism cellular localization GO:1902580 332 0.043
modification dependent protein catabolic process GO:0019941 209 0.043
regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000622 3 0.043
mitotic nuclear division GO:0007067 119 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.042
negative regulation of histone modification GO:0031057 19 0.041
negative regulation of response to dna damage stimulus GO:2001021 33 0.041
ribonucleoside triphosphate metabolic process GO:0009199 412 0.041
regulation of cytoplasmic mrna processing body assembly GO:0010603 5 0.040
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 8 0.040
mrna processing GO:0006397 133 0.039
positive regulation of mrna 3 end processing GO:0031442 12 0.038
purine nucleotide catabolic process GO:0006195 405 0.038
protein complex disassembly GO:0043241 52 0.037
cellular response to external stimulus GO:0071496 111 0.036
rna interference GO:0016246 4 0.035
protein localization to organelle GO:0033365 280 0.035
organelle fission GO:0048285 149 0.034
oocyte differentiation GO:0009994 2 0.034
oocyte development GO:0048599 1 0.034
single organism carbohydrate metabolic process GO:0044723 193 0.033
canonical wnt signaling pathway GO:0060070 116 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
negative regulation of chromatin modification GO:1903309 21 0.032
nucleus localization GO:0051647 1 0.032
anterior posterior axis specification GO:0009948 2 0.032
protein localization to membrane GO:0072657 160 0.031
protein dna complex subunit organization GO:0071824 80 0.031
positive regulation of organelle assembly GO:1902117 17 0.031
positive regulation of mrna catabolic process GO:0061014 10 0.030
regulation of establishment of protein localization GO:0070201 242 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.030
regulation of protein maturation GO:1903317 150 0.030
response to external biotic stimulus GO:0043207 261 0.030
regulation of mrna catabolic process GO:0061013 13 0.030
nucleotide catabolic process GO:0009166 408 0.029
oogenesis GO:0048477 2 0.029
positive regulation of cell division GO:0051781 59 0.029
regulation of cell division GO:0051302 116 0.029
regulation of mrna 3 end processing GO:0031440 12 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
recombinational repair GO:0000725 50 0.028
response to biotic stimulus GO:0009607 276 0.028
spermatid differentiation GO:0048515 4 0.028
negative regulation of protein processing GO:0010955 142 0.028
mapk cascade GO:0000165 288 0.027
mitotic cell cycle process GO:1903047 286 0.027
autophagy GO:0006914 88 0.027
regulation of intracellular protein transport GO:0033157 123 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
histone h2a ubiquitination GO:0033522 17 0.026
ribonucleoprotein complex subunit organization GO:0071826 81 0.026
positive regulation of meiotic cell cycle GO:0051446 2 0.026
plasma membrane organization GO:0007009 115 0.026
regulation of cellular response to stress GO:0080135 244 0.026
regulation of nuclear division GO:0051783 65 0.026
negative regulation of cellular catabolic process GO:0031330 83 0.026
multi organism reproductive process GO:0044703 54 0.026
Mouse
protein processing GO:0016485 226 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.025
protein alkylation GO:0008213 74 0.025
cellular response to endogenous stimulus GO:0071495 336 0.025
methylation GO:0032259 106 0.025
regulation of mrna metabolic process GO:1903311 53 0.024
nuclear transport GO:0051169 179 0.024
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.024
protein ubiquitination GO:0016567 314 0.024
sex differentiation GO:0007548 45 0.023
regulation of canonical wnt signaling pathway GO:0060828 88 0.023
organophosphate catabolic process GO:0046434 430 0.023
reproductive process GO:0022414 106 0.023
Mouse
negative regulation of organelle organization GO:0010639 126 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
negative regulation of proteolysis GO:0045861 132 0.023
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.022
memory GO:0007613 3 0.022
Mouse
positive regulation of transport GO:0051050 336 0.022
cellular amino acid metabolic process GO:0006520 116 0.022
positive regulation of protein catabolic process GO:0045732 75 0.022
regulation of protein processing GO:0070613 150 0.022
covalent chromatin modification GO:0016569 254 0.022
translational initiation GO:0006413 48 0.022
regulation of protein localization to nucleus GO:1900180 85 0.021
cytoplasmic mrna processing body assembly GO:0033962 10 0.021
positive regulation of mrna metabolic process GO:1903313 19 0.021
spermatid development GO:0007286 4 0.021
amine metabolic process GO:0009308 44 0.021
histone h2a k63 linked ubiquitination GO:0070535 5 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
cellular amine metabolic process GO:0044106 41 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
embryonic hemopoiesis GO:0035162 4 0.021
negative regulation of transport GO:0051051 176 0.021
locomotory behavior GO:0007626 1 0.020
regulation of chromosome organization GO:0033044 103 0.020
gtp metabolic process GO:0046039 239 0.020
cellular ketone metabolic process GO:0042180 80 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
negative regulation of cell death GO:0060548 345 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
negative regulation of protein maturation GO:1903318 142 0.020
positive regulation of wnt signaling pathway GO:0030177 54 0.020
regulation of protein kinase activity GO:0045859 289 0.020
cytokinesis GO:0000910 96 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
chromatin modification GO:0016568 298 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
immune system development GO:0002520 195 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
meiotic nuclear division GO:0007126 10 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
regulation of transferase activity GO:0051338 355 0.019
dna recombination GO:0006310 77 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
protein localization to nucleus GO:0034504 136 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
establishment of nucleus localization GO:0040023 1 0.019
lipid metabolic process GO:0006629 381 0.019
macromolecular complex disassembly GO:0032984 60 0.019
regulation of mapk cascade GO:0043408 262 0.019
anterior posterior axis specification embryo GO:0008595 2 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
endocytosis GO:0006897 159 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
positive regulation of catenin import into nucleus GO:0035413 9 0.018
regulation of growth GO:0040008 165 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
regulation of protein ubiquitination GO:0031396 95 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.018
determination of adult lifespan GO:0008340 2 0.018
regulation of protein import into nucleus GO:0042306 78 0.018
endomembrane system organization GO:0010256 196 0.018
response to extracellular stimulus GO:0009991 85 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.017
protein methylation GO:0006479 74 0.017
regulation of cell cycle GO:0051726 393 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
regulation of protein targeting GO:1903533 91 0.017
regulation of protein localization GO:0032880 296 0.017
protein maturation GO:0051604 233 0.017
mrna splicing via spliceosome GO:0000398 89 0.017
ras protein signal transduction GO:0007265 73 0.017
internal peptidyl lysine acetylation GO:0018393 97 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
regulation of cell maturation GO:1903429 3 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
cell growth GO:0016049 160 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
regulation of protein catabolic process GO:0042176 155 0.016
vesicle mediated transport GO:0016192 371 0.016
stress activated mapk cascade GO:0051403 93 0.016
heart development GO:0007507 95 0.016
protein k63 linked ubiquitination GO:0070534 31 0.016
protein acetylation GO:0006473 116 0.016
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.015
positive regulation of intracellular protein transport GO:0090316 76 0.015
regulation of protein transport GO:0051223 213 0.015
glycerolipid metabolic process GO:0046486 107 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
membrane organization GO:0061024 292 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
regulation of chromatin modification GO:1903308 51 0.015
regulation of cell growth GO:0001558 135 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
rab protein signal transduction GO:0032482 4 0.014
cilium assembly GO:0042384 63 0.014
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.014
regulation of catenin import into nucleus GO:0035412 18 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
cilium organization GO:0044782 68 0.014
nuclear import GO:0051170 106 0.014
receptor metabolic process GO:0043112 81 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
postreplication repair GO:0006301 12 0.014
regulation of dna metabolic process GO:0051052 153 0.014
positive regulation of nuclear division GO:0051785 27 0.014
long term memory GO:0007616 2 0.014
regulation of oocyte development GO:0060281 1 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
hemopoiesis GO:0030097 180 0.014
rna splicing GO:0008380 131 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
macromolecule methylation GO:0043414 97 0.013
cytoplasmic transport GO:0016482 379 0.013
nuclear migration GO:0007097 1 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
regulation of peptide transport GO:0090087 62 0.013
cell cycle g1 s phase transition GO:0044843 80 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
development of primary sexual characteristics GO:0045137 35 0.013
regulation of peptidase activity GO:0052547 180 0.013
response to other organism GO:0051707 261 0.013
positive regulation of proteolysis GO:0045862 142 0.013
blastoderm segmentation GO:0007350 2 0.013
regulation of intracellular transport GO:0032386 195 0.013
gonad development GO:0008406 34 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
multicellular organismal aging GO:0010259 3 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
regulation of response to dna damage stimulus GO:2001020 94 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
chromatin organization GO:0006325 351 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
oxidation reduction process GO:0055114 396 0.012
adult locomotory behavior GO:0008344 1 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
chromosome segregation GO:0007059 114 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.012
cell cycle phase transition GO:0044770 173 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
reproduction GO:0000003 63 0.012
Mouse
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
peptide transport GO:0015833 74 0.012
response to abiotic stimulus GO:0009628 336 0.012
double strand break repair via homologous recombination GO:0000724 50 0.012
single organism membrane organization GO:0044802 268 0.012
amide transport GO:0042886 76 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
response to inorganic substance GO:0010035 127 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.012
reproductive system development GO:0061458 56 0.012
regulation of ras gtpase activity GO:0032318 128 0.011
regulation of rab gtpase activity GO:0032313 39 0.011
neuromuscular junction development GO:0007528 3 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
immune response GO:0006955 307 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
apoptotic signaling pathway GO:0097190 268 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of cytokine production GO:0001817 232 0.011
regulation of locomotion GO:0040012 329 0.011
negative regulation of cell cycle GO:0045786 193 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
catenin import into nucleus GO:0035411 18 0.011
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.011
carbohydrate metabolic process GO:0005975 207 0.011
gene silencing by rna GO:0031047 26 0.011
positive regulation of meiosis i GO:0060903 1 0.011
histone ubiquitination GO:0016574 31 0.011
response to ionizing radiation GO:0010212 65 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
atp catabolic process GO:0006200 157 0.011
system process GO:0003008 349 0.011
Mouse
regeneration GO:0031099 4 0.011
protein acylation GO:0043543 138 0.011
segmentation GO:0035282 4 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
dephosphorylation GO:0016311 209 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.010
regulation of mitochondrion organization GO:0010821 54 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010
negative regulation of transferase activity GO:0051348 124 0.010
embryo development GO:0009790 123 0.010
camp metabolic process GO:0046058 61 0.010
protein modification by small protein conjugation GO:0032446 342 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
response to nutrient levels GO:0031667 81 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
meiotic chromosome segregation GO:0045132 4 0.010
regulation of carbohydrate metabolic process GO:0006109 54 0.010
regulation of organelle assembly GO:1902115 40 0.010
cellular lipid metabolic process GO:0044255 303 0.010
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.010
positive regulation of phosphorylation GO:0042327 394 0.010
histone modification GO:0016570 251 0.010
protein import GO:0017038 130 0.010

PAIP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.027
nervous system disease DOID:863 431 0.027
immune system disease DOID:2914 155 0.017
hematopoietic system disease DOID:74 100 0.017
anemia DOID:2355 55 0.016
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
organ system cancer DOID:0050686 164 0.016
neurodegenerative disease DOID:1289 102 0.016
sensory system disease DOID:0050155 203 0.011
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011