Homo sapiens

0 known processes

UBE2L6

ubiquitin-conjugating enzyme E2L 6

(Aliases: UBCH8,MGC40331,RIG-B)

UBE2L6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.972
viral life cycle GO:0019058 132 0.942
interspecies interaction between organisms GO:0044419 156 0.925
modification dependent protein catabolic process GO:0019941 209 0.920
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.920
viral process GO:0016032 146 0.862
regulation of viral genome replication GO:0045069 48 0.822
immune response GO:0006955 307 0.821
immune effector process GO:0002252 159 0.766
protein modification by small protein conjugation GO:0032446 342 0.725
Human
defense response GO:0006952 315 0.710
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.707
Mouse
cellular response to cytokine stimulus GO:0071345 181 0.690
negative regulation of multi organism process GO:0043901 92 0.673
negative regulation of viral process GO:0048525 66 0.661
regulation of viral process GO:0050792 103 0.608
multi organism cellular process GO:0044764 156 0.608
defense response to virus GO:0051607 71 0.557
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.523
protein ubiquitination GO:0016567 314 0.497
Human
multi organism metabolic process GO:0044033 41 0.478
entry into host GO:0044409 25 0.469
negative regulation of cellular protein metabolic process GO:0032269 353 0.466
regulation of apoptotic signaling pathway GO:2001233 175 0.464
cellular protein catabolic process GO:0044257 261 0.450
Mouse
protein catabolic process GO:0030163 325 0.418
Mouse
ubiquitin dependent protein catabolic process GO:0006511 206 0.400
defense response to other organism GO:0098542 129 0.384
negative regulation of cell death GO:0060548 345 0.376
innate immune response GO:0045087 178 0.373
negative regulation of viral genome replication GO:0045071 35 0.350
positive regulation of immune system process GO:0002684 283 0.349
response to other organism GO:0051707 261 0.338
regulation of viral transcription GO:0046782 34 0.301
modification dependent macromolecule catabolic process GO:0043632 212 0.296
Mouse
response to interferon alpha GO:0035455 11 0.294
interaction with host GO:0051701 42 0.294
cellular macromolecule catabolic process GO:0044265 380 0.287
Mouse
response to virus GO:0009615 126 0.279
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.274
negative regulation of cell motility GO:2000146 104 0.265
regulation of intracellular transport GO:0032386 195 0.247
viral genome replication GO:0019079 50 0.246
regulation of cell differentiation GO:0045595 393 0.229
protein polyubiquitination GO:0000209 110 0.216
Human
viral gene expression GO:0019080 35 0.213
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.213
Human
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.200
negative regulation of locomotion GO:0040013 118 0.198
intracellular transport of virus GO:0075733 14 0.196
positive regulation of developmental process GO:0051094 314 0.192
positive regulation of rig i signaling pathway GO:1900246 4 0.192
protein maturation GO:0051604 233 0.191
response to external biotic stimulus GO:0043207 261 0.187
positive regulation of cell differentiation GO:0045597 211 0.185
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.158
negative regulation of catalytic activity GO:0043086 335 0.153
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.149
regulation of viral entry into host cell GO:0046596 17 0.142
negative regulation of cell proliferation GO:0008285 228 0.138
cytokine mediated signaling pathway GO:0019221 109 0.132
viral transcription GO:0019083 35 0.127
regulation of cell migration GO:0030334 289 0.120
regulation of immune response GO:0050776 201 0.117
regulation of locomotion GO:0040012 329 0.115
negative regulation of viral entry into host cell GO:0046597 12 0.114
positive regulation of programmed cell death GO:0043068 249 0.114
regulation of cell motility GO:2000145 299 0.113
intracellular protein transport GO:0006886 270 0.113
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.111
negative regulation of cell migration GO:0030336 102 0.110
mitochondrion organization GO:0007005 156 0.108
nuclear transport GO:0051169 179 0.105
entry into host cell GO:0030260 25 0.102
cytokine production GO:0001816 247 0.100
response to biotic stimulus GO:0009607 276 0.100
regulation of proteolysis GO:0030162 293 0.098
negative regulation of protein metabolic process GO:0051248 391 0.098
response to type i interferon GO:0034340 14 0.097
regulation of protein transport GO:0051223 213 0.096
nucleocytoplasmic transport GO:0006913 176 0.095
cytoplasmic transport GO:0016482 379 0.093
multi organism localization GO:1902579 14 0.091
regulation of transferase activity GO:0051338 355 0.090
Human
i kappab kinase nf kappab signaling GO:0007249 166 0.087
positive regulation of apoptotic process GO:0043065 246 0.084
regulation of protein export from nucleus GO:0046825 15 0.083
regulation of cellular component movement GO:0051270 334 0.082
negative regulation of protein maturation GO:1903318 142 0.079
negative regulation of cellular component movement GO:0051271 106 0.079
nucleoside phosphate biosynthetic process GO:1901293 109 0.078
positive regulation of osteoblast differentiation GO:0045669 23 0.075
negative regulation of programmed cell death GO:0043069 321 0.075
negative regulation of peptidase activity GO:0010466 91 0.074
positive regulation of cell death GO:0010942 263 0.071
regulation of establishment of protein localization GO:0070201 242 0.070
regulation of peptidase activity GO:0052547 180 0.070
cellular macromolecular complex assembly GO:0034622 324 0.068
regulation of endopeptidase activity GO:0052548 170 0.067
chemical homeostasis GO:0048878 306 0.065
negative regulation of viral transcription GO:0032897 23 0.063
cellular lipid metabolic process GO:0044255 303 0.060
viral entry into host cell GO:0046718 24 0.059
regulation of protein ubiquitination GO:0031396 95 0.059
Human
negative regulation of multicellular organismal process GO:0051241 317 0.058
cardiovascular system development GO:0072358 262 0.058
regulation of cytoskeleton organization GO:0051493 177 0.058
negative regulation of phosphate metabolic process GO:0045936 267 0.056
leukocyte activation GO:0045321 164 0.055
positive regulation of proteolysis GO:0045862 142 0.055
regulation of intracellular transport of viral material GO:1901252 2 0.054
establishment of protein localization to organelle GO:0072594 172 0.054
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.051
regulation of anatomical structure morphogenesis GO:0022603 286 0.051
negative regulation of endopeptidase activity GO:0010951 84 0.050
single organism cellular localization GO:1902580 332 0.049
positive regulation of endopeptidase activity GO:0010950 84 0.049
regulation of actin filament based process GO:0032970 141 0.047
metal ion transport GO:0030001 272 0.047
regulation of cytoplasmic transport GO:1903649 149 0.046
cellular response to type i interferon GO:0071357 12 0.045
secretion GO:0046903 254 0.044
negative regulation of protein processing GO:0010955 142 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
protein processing GO:0016485 226 0.044
cation transport GO:0006812 331 0.041
anatomical structure homeostasis GO:0060249 100 0.041
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.040
osteoblast differentiation GO:0001649 92 0.040
positive regulation of viral entry into host cell GO:0046598 3 0.039
negative regulation of protein modification process GO:0031400 200 0.039
response to interferon gamma GO:0034341 39 0.039
protein localization to organelle GO:0033365 280 0.038
apoptotic signaling pathway GO:0097190 268 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.037
immune response activating signal transduction GO:0002757 90 0.037
hematopoietic or lymphoid organ development GO:0048534 186 0.037
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.037
negative regulation of intracellular transport of viral material GO:1901253 2 0.037
extrinsic apoptotic signaling pathway GO:0097191 119 0.036
epinephrine secretion GO:0048242 1 0.035
organ morphogenesis GO:0009887 147 0.035
regulation of protein catabolic process GO:0042176 155 0.035
positive regulation of actin filament polymerization GO:0030838 38 0.035
secretion by cell GO:0032940 226 0.035
regulation of membrane depolarization GO:0003254 19 0.034
interferon gamma production GO:0032609 39 0.033
mitotic cell cycle GO:0000278 326 0.033
cellular component morphogenesis GO:0032989 314 0.033
cellular protein complex assembly GO:0043623 188 0.033
negative regulation of apoptotic process GO:0043066 316 0.033
regulation of cysteine type endopeptidase activity GO:2000116 127 0.032
regulation of cytokine production GO:0001817 232 0.032
activation of cysteine type endopeptidase activity GO:0097202 57 0.031
negative regulation of apoptotic signaling pathway GO:2001234 97 0.031
negative regulation of transport GO:0051051 176 0.031
regulation of multi organism process GO:0043900 157 0.030
positive regulation of cell cycle GO:0045787 140 0.029
t cell proliferation GO:0042098 45 0.029
type i interferon signaling pathway GO:0060337 11 0.029
regulation of protein deubiquitination GO:0090085 4 0.029
regulation of cell cycle GO:0051726 393 0.028
regulation of membrane potential GO:0042391 95 0.028
regulation of binding GO:0051098 111 0.028
entry into other organism involved in symbiotic interaction GO:0051828 25 0.027
regulation of secretion by cell GO:1903530 177 0.027
divalent metal ion transport GO:0070838 152 0.027
positive regulation of hydrolase activity GO:0051345 331 0.027
negative regulation of protein phosphorylation GO:0001933 140 0.026
antigen receptor mediated signaling pathway GO:0050851 38 0.026
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
mitotic cell cycle process GO:1903047 286 0.025
mapk cascade GO:0000165 288 0.025
regulation of kinase activity GO:0043549 314 0.025
post embryonic development GO:0009791 2 0.025
leukocyte mediated immunity GO:0002443 59 0.025
positive regulation of interleukin 13 production GO:0032736 4 0.025
regulation of dna metabolic process GO:0051052 153 0.025
nervous system development GO:0007399 293 0.025
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.024
positive regulation of multi organism process GO:0043902 56 0.024
purine ribonucleotide catabolic process GO:0009154 404 0.024
muscle structure development GO:0061061 98 0.024
regulation of protein localization GO:0032880 296 0.024
multi organism transport GO:0044766 14 0.024
positive regulation of peptidase activity GO:0010952 88 0.024
response to cytokine GO:0034097 232 0.024
positive regulation of cellular component biogenesis GO:0044089 158 0.023
cytidine metabolic process GO:0046087 7 0.023
regulation of protein stability GO:0031647 87 0.023
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.023
transmembrane transport GO:0055085 399 0.023
positive regulation of cellular component organization GO:0051130 376 0.022
response to interferon beta GO:0035456 11 0.022
female gamete generation GO:0007292 2 0.022
positive regulation of intracellular transport GO:0032388 104 0.022
proteasomal protein catabolic process GO:0010498 176 0.022
glycosylation GO:0070085 71 0.022
negative regulation of proteolysis GO:0045861 132 0.022
nuclear export GO:0051168 69 0.021
regulation of cellular protein catabolic process GO:1903362 96 0.021
negative regulation of kinase activity GO:0033673 106 0.021
positive regulation of cytokine production GO:0001819 167 0.021
movement in host environment GO:0052126 25 0.021
ion transmembrane transport GO:0034220 338 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.021
natural killer cell mediated immunity GO:0002228 23 0.021
determination of adult lifespan GO:0008340 2 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
positive regulation of response to external stimulus GO:0032103 88 0.020
protein export from nucleus GO:0006611 29 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.020
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.020
zymogen activation GO:0031638 70 0.020
regulation of defense response to virus GO:0050688 33 0.020
glucose metabolic process GO:0006006 45 0.020
tripartite regional subdivision GO:0007351 2 0.020
developmental programmed cell death GO:0010623 3 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
regulation of actin cytoskeleton organization GO:0032956 116 0.019
membrane organization GO:0061024 292 0.019
regulation of leukocyte activation GO:0002694 115 0.019
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
regulation of protein maturation GO:1903317 150 0.018
positive regulation of viral process GO:0048524 37 0.018
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
endomembrane system organization GO:0010256 196 0.018
circulatory system development GO:0072359 262 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
cell cycle arrest GO:0007050 71 0.017
regulation of response to biotic stimulus GO:0002831 55 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
negative regulation of cytokine production GO:0001818 82 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
ion homeostasis GO:0050801 230 0.016
regulation of osteoblast differentiation GO:0045667 38 0.016
chromatin organization GO:0006325 351 0.016
myeloid cell homeostasis GO:0002262 34 0.016
regulation of fas signaling pathway GO:1902044 2 0.016
regulation of ion homeostasis GO:2000021 73 0.015
regulation of cell growth GO:0001558 135 0.015
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.015
ossification GO:0001503 121 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.015
purine nucleotide biosynthetic process GO:0006164 84 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
negative regulation of cell cycle GO:0045786 193 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.015
protein localization to membrane GO:0072657 160 0.015
nucleotide catabolic process GO:0009166 408 0.015
positive regulation of interferon alpha production GO:0032727 11 0.015
immune response regulating signaling pathway GO:0002764 97 0.015
intracellular receptor signaling pathway GO:0030522 104 0.014
single organism membrane organization GO:0044802 268 0.014
positive regulation of organelle organization GO:0010638 195 0.014
maintenance of location GO:0051235 112 0.014
immune system development GO:0002520 195 0.014
organic hydroxy compound metabolic process GO:1901615 147 0.014
nucleoside catabolic process GO:0009164 408 0.014
multicellular organismal aging GO:0010259 3 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
protein k63 linked ubiquitination GO:0070534 31 0.013
positive regulation of transport GO:0051050 336 0.013
regulation of lymphocyte activation GO:0051249 103 0.013
regulation of secretion GO:0051046 194 0.013
regulation of leukocyte proliferation GO:0070663 67 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
negative regulation of protein transport GO:0051224 75 0.013
positive regulation of locomotion GO:0040017 186 0.013
positive regulation of immune response GO:0050778 159 0.013
regulation of mononuclear cell proliferation GO:0032944 65 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
negative regulation of interleukin 2 secretion GO:1900041 2 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.013
regulation of gene expression epigenetic GO:0040029 73 0.012
regulation of response to cytokine stimulus GO:0060759 46 0.012
rig i signaling pathway GO:0039529 7 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
positive regulation of protein transport GO:0051222 135 0.012
antigen processing and presentation of exogenous antigen GO:0019884 4 0.012
positive regulation of secretion GO:0051047 116 0.012
negative regulation of intracellular transport GO:0032387 60 0.012
negative regulation of immune system process GO:0002683 136 0.012
response to nitrogen compound GO:1901698 184 0.012
regulation of innate immune response GO:0045088 97 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
response to tumor necrosis factor GO:0034612 76 0.012
negative regulation of protein ubiquitination GO:0031397 35 0.012
response to corticosteroid GO:0031960 15 0.012
Human
adenosine to inosine editing GO:0006382 3 0.012
negative regulation of cellular component organization GO:0051129 235 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.011
regulation of homeostatic process GO:0032844 121 0.011
protein targeting to nucleus GO:0044744 104 0.011
regulation of transmembrane transport GO:0034762 139 0.011
regulation of immune effector process GO:0002697 91 0.011
apoptotic mitochondrial changes GO:0008637 57 0.011
actin polymerization or depolymerization GO:0008154 56 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.011
regulation of anatomical structure size GO:0090066 101 0.011
positive regulation of cell development GO:0010720 92 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.011
spindle elongation GO:0051231 4 0.011
atp metabolic process GO:0046034 176 0.011
cellular response to external stimulus GO:0071496 111 0.011
glycoprotein metabolic process GO:0009100 110 0.011
retrograde transport endosome to golgi GO:0042147 45 0.011
positive regulation of kinase activity GO:0033674 204 0.011
blood vessel morphogenesis GO:0048514 162 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
lipoprotein metabolic process GO:0042157 42 0.010
regulation of cytokine mediated signaling pathway GO:0001959 41 0.010
regulation of growth GO:0040008 165 0.010
purine containing compound catabolic process GO:0072523 411 0.010
regulation of protein processing GO:0070613 150 0.010
regulation of cellular component size GO:0032535 82 0.010
negative regulation of binding GO:0051100 57 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
cell cycle phase transition GO:0044770 173 0.010
Human
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.010
response to bacterium GO:0009617 144 0.010
antigen processing and presentation GO:0019882 33 0.010

UBE2L6 disease predictions

Disease DO term ID Size Probability Func Analog Org
aicardi goutieres syndrome DOID:0050629 7 0.042
urinary system disease DOID:18 40 0.037
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.018
sensory system disease DOID:0050155 203 0.012
eye and adnexa disease DOID:1492 150 0.012
nervous system disease DOID:863 431 0.012
eye disease DOID:5614 149 0.012
diabetes mellitus DOID:9351 31 0.011
disease of metabolism DOID:0014667 295 0.011
carbohydrate metabolism disease DOID:0050013 32 0.011
glucose metabolism disease DOID:4194 32 0.011
acquired metabolic disease DOID:0060158 58 0.011