Homo sapiens

109 known processes

UBE2L3

ubiquitin-conjugating enzyme E2L 3

(Aliases: UbcM4,E2-F1,UBCH7,L-UBC)

UBE2L3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.978
protein polyubiquitination GO:0000209 110 0.968
protein k48 linked ubiquitination GO:0070936 38 0.894
protein ubiquitination GO:0016567 314 0.880
protein k63 linked ubiquitination GO:0070534 31 0.592
modification dependent macromolecule catabolic process GO:0043632 212 0.558
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.505
cell development GO:0048468 328 0.489
cellular protein catabolic process GO:0044257 261 0.423
cellular macromolecule catabolic process GO:0044265 380 0.393
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.343
protein catabolic process GO:0030163 325 0.327
modification dependent protein catabolic process GO:0019941 209 0.308
oogenesis GO:0048477 2 0.301
female gamete generation GO:0007292 2 0.285
ubiquitin dependent protein catabolic process GO:0006511 206 0.235
post embryonic development GO:0009791 2 0.175
regulation of protein ubiquitination GO:0031396 95 0.153
chromatin organization GO:0006325 351 0.151
protein monoubiquitination GO:0006513 39 0.137
cellular macromolecular complex assembly GO:0034622 324 0.133
vesicle mediated transport GO:0016192 371 0.110
cell cell signaling GO:0007267 155 0.109
covalent chromatin modification GO:0016569 254 0.103
cellular ketone metabolic process GO:0042180 80 0.102
protein autoubiquitination GO:0051865 37 0.101
immune system development GO:0002520 195 0.094
mapk cascade GO:0000165 288 0.093
nervous system development GO:0007399 293 0.093
chemical homeostasis GO:0048878 306 0.086
histone ubiquitination GO:0016574 31 0.086
secretion by cell GO:0032940 226 0.083
positive regulation of cellular catabolic process GO:0031331 284 0.081
negative regulation of cellular component organization GO:0051129 235 0.079
generation of neurons GO:0048699 152 0.078
chromatin modification GO:0016568 298 0.076
growth GO:0040007 202 0.075
histone modification GO:0016570 251 0.074
cellular homeostasis GO:0019725 196 0.068
rna splicing via transesterification reactions GO:0000375 90 0.068
mrna processing GO:0006397 133 0.065
hematopoietic or lymphoid organ development GO:0048534 186 0.063
regulation of cellular ketone metabolic process GO:0010565 50 0.062
hindbrain development GO:0030902 3 0.060
mitotic nuclear division GO:0007067 119 0.060
determination of adult lifespan GO:0008340 2 0.059
positive regulation of developmental process GO:0051094 314 0.057
cell cycle phase transition GO:0044770 173 0.055
single organism cellular localization GO:1902580 332 0.055
regulation of mitotic cell cycle GO:0007346 189 0.055
nitrogen compound transport GO:0071705 191 0.054
neuromuscular junction development GO:0007528 3 0.054
divalent inorganic cation homeostasis GO:0072507 136 0.053
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.052
secretion GO:0046903 254 0.052
purine containing compound catabolic process GO:0072523 411 0.051
positive regulation of programmed cell death GO:0043068 249 0.049
positive regulation of cellular component organization GO:0051130 376 0.049
ion homeostasis GO:0050801 230 0.048
hemopoiesis GO:0030097 180 0.044
mitotic cell cycle process GO:1903047 286 0.043
anatomical structure formation involved in morphogenesis GO:0048646 284 0.043
signal transduction by phosphorylation GO:0023014 297 0.042
regulation of cellular amine metabolic process GO:0033238 11 0.040
cellular cation homeostasis GO:0030003 163 0.040
locomotory behavior GO:0007626 1 0.039
positive regulation of cellular component biogenesis GO:0044089 158 0.039
regulation of protein transport GO:0051223 213 0.039
transmembrane transport GO:0055085 399 0.039
positive regulation of cell cycle GO:0045787 140 0.039
regulation of establishment of protein localization GO:0070201 242 0.038
regulation of protein localization GO:0032880 296 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.036
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.035
intracellular protein transport GO:0006886 270 0.035
single organism reproductive process GO:0044702 98 0.034
amine metabolic process GO:0009308 44 0.033
regulation of cellular component biogenesis GO:0044087 281 0.033
negative regulation of protein transport GO:0051224 75 0.033
cell projection organization GO:0030030 252 0.033
protein deubiquitination GO:0016579 79 0.032
negative regulation of programmed cell death GO:0043069 321 0.032
positive regulation of catabolic process GO:0009896 310 0.032
regulation of mapk cascade GO:0043408 262 0.031
cytoplasmic transport GO:0016482 379 0.030
proteasomal protein catabolic process GO:0010498 176 0.030
endocytosis GO:0006897 159 0.030
cation transport GO:0006812 331 0.030
regulation of nucleotide metabolic process GO:0006140 269 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
cellular lipid metabolic process GO:0044255 303 0.029
ribonucleoprotein complex assembly GO:0022618 78 0.029
negative regulation of cell death GO:0060548 345 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.029
neurogenesis GO:0022008 169 0.029
oocyte development GO:0048599 1 0.028
multicellular organismal aging GO:0010259 3 0.028
cation homeostasis GO:0055080 189 0.028
small gtpase mediated signal transduction GO:0007264 78 0.028
regulation of cell cycle GO:0051726 393 0.028
cytosolic calcium ion homeostasis GO:0051480 89 0.028
regulation of secretion by cell GO:1903530 177 0.028
anterior posterior axis specification GO:0009948 2 0.028
regulation of cellular protein catabolic process GO:1903362 96 0.027
regulation of protein complex assembly GO:0043254 147 0.027
intracellular protein transmembrane transport GO:0065002 24 0.027
positive regulation of apoptotic process GO:0043065 246 0.027
cellular metal ion homeostasis GO:0006875 146 0.026
organelle localization GO:0051640 84 0.026
regulation of peptide transport GO:0090087 62 0.026
maintenance of location GO:0051235 112 0.026
Worm
circulatory system development GO:0072359 262 0.025
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.025
single organism membrane organization GO:0044802 268 0.025
cellular component morphogenesis GO:0032989 314 0.025
negative regulation of phosphorylation GO:0042326 174 0.025
regulation of translation GO:0006417 89 0.024
oocyte differentiation GO:0009994 2 0.024
positive regulation of proteolysis GO:0045862 142 0.024
membrane organization GO:0061024 292 0.023
protein maturation GO:0051604 233 0.023
positive regulation of protein ubiquitination GO:0031398 53 0.022
protein localization to membrane GO:0072657 160 0.022
protein localization to organelle GO:0033365 280 0.022
cellular amino acid metabolic process GO:0006520 116 0.022
membrane fusion GO:0061025 43 0.022
nuclear migration GO:0007097 1 0.022
peripheral nervous system development GO:0007422 2 0.022
apoptotic signaling pathway GO:0097190 268 0.022
regulation of ras protein signal transduction GO:0046578 155 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
cellular protein complex assembly GO:0043623 188 0.020
cellular chemical homeostasis GO:0055082 180 0.020
mitotic cell cycle GO:0000278 326 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
ras protein signal transduction GO:0007265 73 0.020
protein depolymerization GO:0051261 30 0.019
cell growth GO:0016049 160 0.019
blastoderm segmentation GO:0007350 2 0.019
reproductive process GO:0022414 106 0.019
cytokine production GO:0001816 247 0.019
protein processing GO:0016485 226 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
maintenance of location in cell GO:0051651 62 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
protein targeting GO:0006605 187 0.019
adult locomotory behavior GO:0008344 1 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
fatty acid biosynthetic process GO:0006633 46 0.018
actin filament based process GO:0030029 224 0.018
cellular amine metabolic process GO:0044106 41 0.018
ribonucleoprotein complex subunit organization GO:0071826 81 0.018
regulation of ion transport GO:0043269 189 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
organelle assembly GO:0070925 176 0.018
establishment of nucleus localization GO:0040023 1 0.018
hematopoietic stem cell proliferation GO:0071425 6 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
carboxylic acid biosynthetic process GO:0046394 97 0.018
positive regulation of immune system process GO:0002684 283 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
amide transport GO:0042886 76 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
protein acylation GO:0043543 138 0.017
endomembrane system organization GO:0010256 196 0.017
intracellular protein transmembrane import GO:0044743 23 0.017
regulation of intracellular transport GO:0032386 195 0.017
regulation of actin filament based process GO:0032970 141 0.017
regulation of kinase activity GO:0043549 314 0.017
response to oxygen containing compound GO:1901700 369 0.017
positive regulation of transport GO:0051050 336 0.017
dna repair GO:0006281 198 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
cellular calcium ion homeostasis GO:0006874 117 0.017
endosomal transport GO:0016197 129 0.017
negative regulation of protein modification process GO:0031400 200 0.016
positive regulation of protein complex assembly GO:0031334 86 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
lipid metabolic process GO:0006629 381 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
regulation of proteolysis GO:0030162 293 0.016
positive regulation of ligase activity GO:0051351 19 0.016
developmental programmed cell death GO:0010623 3 0.016
protein import GO:0017038 130 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
system process GO:0003008 349 0.016
cell part morphogenesis GO:0032990 137 0.016
divalent metal ion transport GO:0070838 152 0.016
regulation of meiotic cell cycle GO:0051445 4 0.016
establishment of organelle localization GO:0051656 59 0.015
regulation of cell cycle process GO:0010564 266 0.015
developmental cell growth GO:0048588 18 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
negative regulation of organelle organization GO:0010639 126 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
striated muscle contraction GO:0006941 52 0.015
positive regulation of apoptotic signaling pathway GO:2001235 70 0.015
golgi vesicle transport GO:0048193 80 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
peptide transport GO:0015833 74 0.015
neuron development GO:0048666 113 0.015
response to nutrient levels GO:0031667 81 0.015
cellular divalent inorganic cation homeostasis GO:0072503 128 0.014
segmentation GO:0035282 4 0.014
positive regulation of secretion by cell GO:1903532 108 0.014
oxidation reduction process GO:0055114 396 0.014
multicellular organismal reproductive process GO:0048609 40 0.014
regulation of transmembrane transport GO:0034762 139 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
gtp catabolic process GO:0006184 237 0.014
regulation of chromosome organization GO:0033044 103 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
organ morphogenesis GO:0009887 147 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
developmental growth GO:0048589 48 0.013
metal ion transport GO:0030001 272 0.013
regulation of ubiquitin protein transferase activity GO:0051438 28 0.013
signal release GO:0023061 70 0.013
nuclear transport GO:0051169 179 0.013
regulation of metal ion transport GO:0010959 120 0.012
multicellular organism reproduction GO:0032504 42 0.012
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.012
maintenance of protein location in cell GO:0032507 56 0.012
behavior GO:0007610 112 0.012
meiotic chromosome segregation GO:0045132 4 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
protein targeting to nucleus GO:0044744 104 0.012
central nervous system development GO:0007417 123 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
positive regulation of organelle organization GO:0010638 195 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
embryo development GO:0009790 123 0.012
ribonucleoside catabolic process GO:0042454 406 0.012
monosaccharide metabolic process GO:0005996 74 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
response to inorganic substance GO:0010035 127 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
endoplasmic reticulum organization GO:0007029 20 0.011
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
cardiac muscle cell apoptotic process GO:0010659 3 0.011
regulation of protein deubiquitination GO:0090085 4 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
nucleus localization GO:0051647 1 0.011
organophosphate catabolic process GO:0046434 430 0.011
microtubule based process GO:0007017 210 0.011
pattern specification process GO:0007389 43 0.011
rna splicing GO:0008380 131 0.011
cellular response to glucocorticoid stimulus GO:0071385 4 0.011
neuron differentiation GO:0030182 138 0.011
protein dephosphorylation GO:0006470 81 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
cell morphogenesis GO:0000902 296 0.011
response to fungus GO:0009620 4 0.011
cellular response to oxygen levels GO:0071453 55 0.011
mrna metabolic process GO:0016071 175 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
multi organism reproductive process GO:0044703 54 0.011
spermatid differentiation GO:0048515 4 0.010
regulation of cytokine production GO:0001817 232 0.010
organic acid biosynthetic process GO:0016053 97 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
regulation of chromatin organization GO:1902275 56 0.010
regulation of protein targeting GO:1903533 91 0.010
immune effector process GO:0002252 159 0.010
positive regulation of gtp catabolic process GO:0033126 166 0.010
reproduction GO:0000003 63 0.010
cell projection morphogenesis GO:0048858 129 0.010
cellular ion homeostasis GO:0006873 168 0.010

UBE2L3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.047
nervous system disease DOID:863 431 0.047
cancer DOID:162 167 0.044
disease of cellular proliferation DOID:14566 174 0.044
organ system cancer DOID:0050686 164 0.037
neurodegenerative disease DOID:1289 102 0.025
parkinson s disease DOID:14330 18 0.010
synucleinopathy DOID:0050890 22 0.010