Homo sapiens

0 known processes

IKZF1

IKAROS family zinc finger 1 (Ikaros)

(Aliases: IK1,Hs.54452,LYF1,IKAROS,PRO0758,hIk-1,ZNFN1A1)

IKZF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell activation GO:0001775 213 0.282
Zebrafish Mouse
post embryonic development GO:0009791 2 0.255
response to cytokine GO:0034097 232 0.198
immune response GO:0006955 307 0.192
regulation of cellular ketone metabolic process GO:0010565 50 0.183
regulation of locomotion GO:0040012 329 0.179
regulation of cellular component movement GO:0051270 334 0.166
negative regulation of cell proliferation GO:0008285 228 0.166
cellular amino acid metabolic process GO:0006520 116 0.159
regulation of cell motility GO:2000145 299 0.145
enzyme linked receptor protein signaling pathway GO:0007167 303 0.144
amine metabolic process GO:0009308 44 0.143
regulation of lymphocyte activation GO:0051249 103 0.142
Mouse
ras protein signal transduction GO:0007265 73 0.140
regulation of cellular amine metabolic process GO:0033238 11 0.120
regulation of leukocyte activation GO:0002694 115 0.117
Mouse
regulation of cell activation GO:0050865 125 0.116
Mouse
cellular ketone metabolic process GO:0042180 80 0.115
immune effector process GO:0002252 159 0.113
hematopoietic or lymphoid organ development GO:0048534 186 0.112
Zebrafish Mouse
immune system development GO:0002520 195 0.110
Zebrafish Mouse
regulation of cell differentiation GO:0045595 393 0.109
Mouse
positive regulation of cellular component organization GO:0051130 376 0.105
positive regulation of developmental process GO:0051094 314 0.105
Mouse
regulation of anatomical structure morphogenesis GO:0022603 286 0.102
biological adhesion GO:0022610 331 0.102
t cell activation GO:0042110 99 0.102
Zebrafish Mouse
leukocyte activation GO:0045321 164 0.099
Zebrafish Mouse
lymphocyte activation GO:0046649 133 0.099
Zebrafish Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.096
regulation of immune response GO:0050776 201 0.087
small gtpase mediated signal transduction GO:0007264 78 0.083
response to external biotic stimulus GO:0043207 261 0.081
response to biotic stimulus GO:0009607 276 0.076
response to other organism GO:0051707 261 0.075
positive regulation of cellular amine metabolic process GO:0033240 7 0.074
leukocyte differentiation GO:0002521 98 0.074
Zebrafish Mouse
leukocyte proliferation GO:0070661 74 0.073
mapk cascade GO:0000165 288 0.073
protein autophosphorylation GO:0046777 123 0.071
organ formation GO:0048645 3 0.071
gtp metabolic process GO:0046039 239 0.071
regulation of mononuclear cell proliferation GO:0032944 65 0.070
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.068
oogenesis GO:0048477 2 0.068
defense response GO:0006952 315 0.066
single organism cell adhesion GO:0098602 179 0.066
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.065
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.064
negative regulation of apoptotic process GO:0043066 316 0.063
hemopoiesis GO:0030097 180 0.063
Zebrafish Mouse
negative regulation of cellular amine metabolic process GO:0033239 3 0.062
chromatin organization GO:0006325 351 0.060
regulation of cellular amino acid metabolic process GO:0006521 6 0.060
activation of immune response GO:0002253 114 0.058
immune response regulating signaling pathway GO:0002764 97 0.058
vesicle mediated transport GO:0016192 371 0.058
positive regulation of cell differentiation GO:0045597 211 0.057
Mouse
positive regulation of immune system process GO:0002684 283 0.057
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.056
Mouse
regulation of cell migration GO:0030334 289 0.055
response to growth factor GO:0070848 205 0.055
cell adhesion GO:0007155 325 0.054
endomembrane system organization GO:0010256 196 0.053
regulation of mapk cascade GO:0043408 262 0.053
positive regulation of phosphorylation GO:0042327 394 0.052
response to virus GO:0009615 126 0.051
cell fate commitment involved in pattern specification GO:0060581 1 0.051
signal transduction by phosphorylation GO:0023014 297 0.050
positive regulation of hydrolase activity GO:0051345 331 0.049
taxis GO:0042330 157 0.049
positive regulation of cell proliferation GO:0008284 301 0.048
response to oxygen containing compound GO:1901700 369 0.048
positive regulation of cell activation GO:0050867 81 0.048
Mouse
lymphocyte differentiation GO:0030098 35 0.048
Zebrafish Mouse
positive regulation of cell migration GO:0030335 172 0.047
defense response to other organism GO:0098542 129 0.047
multicellular organismal aging GO:0010259 3 0.046
cell fate determination GO:0001709 3 0.046
single organismal cell cell adhesion GO:0016337 148 0.045
regulation of nucleotide metabolic process GO:0006140 269 0.045
t cell differentiation in thymus GO:0033077 4 0.045
Zebrafish
positive regulation of mapk cascade GO:0043410 190 0.045
histone modification GO:0016570 251 0.045
system process GO:0003008 349 0.044
covalent chromatin modification GO:0016569 254 0.044
female gamete generation GO:0007292 2 0.043
positive regulation of transport GO:0051050 336 0.043
regulation of cytokine production GO:0001817 232 0.043
chromatin modification GO:0016568 298 0.043
wnt signaling pathway GO:0016055 156 0.043
positive regulation of nucleotide metabolic process GO:0045981 230 0.043
ribonucleoside triphosphate metabolic process GO:0009199 412 0.042
cytokine biosynthetic process GO:0042089 37 0.041
cellular response to endogenous stimulus GO:0071495 336 0.041
negative regulation of cellular component organization GO:0051129 235 0.041
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.041
angiogenesis GO:0001525 147 0.041
cellular response to growth factor stimulus GO:0071363 197 0.041
cellular component morphogenesis GO:0032989 314 0.041
regulation of reactive oxygen species metabolic process GO:2000377 41 0.040
positive regulation of gtp catabolic process GO:0033126 166 0.040
organophosphate catabolic process GO:0046434 430 0.040
cellular response to oxygen containing compound GO:1901701 276 0.040
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.040
purine ribonucleoside catabolic process GO:0046130 398 0.039
regulation of response to external stimulus GO:0032101 222 0.039
neuromuscular junction development GO:0007528 3 0.039
azole transport GO:0045117 4 0.039
cellular amine metabolic process GO:0044106 41 0.038
lymphocyte proliferation GO:0046651 70 0.038
blood coagulation GO:0007596 76 0.038
cell development GO:0048468 328 0.037
growth GO:0040007 202 0.037
Mouse
gtp catabolic process GO:0006184 237 0.037
regulation of response to wounding GO:1903034 101 0.037
regulation of protein localization GO:0032880 296 0.037
mononuclear cell proliferation GO:0032943 71 0.037
regulation of t cell activation GO:0050863 77 0.037
Mouse
immune response activating signal transduction GO:0002757 90 0.036
cellular response to cytokine stimulus GO:0071345 181 0.036
regulation of cell adhesion GO:0030155 166 0.036
innate immune response GO:0045087 178 0.035
cell chemotaxis GO:0060326 112 0.035
vasculature development GO:0001944 181 0.035
nucleotide catabolic process GO:0009166 408 0.035
reactive oxygen species metabolic process GO:0072593 75 0.035
negative regulation of cell death GO:0060548 345 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
maintenance of location GO:0051235 112 0.034
glycosyl compound catabolic process GO:1901658 413 0.034
regulation of epithelial cell migration GO:0010632 93 0.034
cytokine production GO:0001816 247 0.034
defense response to virus GO:0051607 71 0.034
regulation of wnt signaling pathway GO:0030111 123 0.034
regulation of cellular response to growth factor stimulus GO:0090287 76 0.034
regulation of transferase activity GO:0051338 355 0.034
regulation of purine nucleotide metabolic process GO:1900542 264 0.033
rho protein signal transduction GO:0007266 26 0.033
positive regulation of locomotion GO:0040017 186 0.033
cellular response to abiotic stimulus GO:0071214 117 0.033
peptidyl lysine modification GO:0018205 144 0.033
ribonucleoside catabolic process GO:0042454 406 0.033
organ morphogenesis GO:0009887 147 0.033
cellular response to dna damage stimulus GO:0006974 379 0.033
negative regulation of programmed cell death GO:0043069 321 0.033
ameboidal type cell migration GO:0001667 135 0.033
regulation of cell development GO:0060284 161 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.032
regulation of rho protein signal transduction GO:0035023 79 0.032
regulation of cytokine biosynthetic process GO:0042035 35 0.032
regulation of cell cycle GO:0051726 393 0.032
response to abiotic stimulus GO:0009628 336 0.032
behavior GO:0007610 112 0.032
dephosphorylation GO:0016311 209 0.032
epithelial cell migration GO:0010631 119 0.031
protein acylation GO:0043543 138 0.031
reproductive process GO:0022414 106 0.031
regulation of immune effector process GO:0002697 91 0.031
cell division GO:0051301 168 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.031
positive regulation of gtpase activity GO:0043547 166 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.030
protein processing GO:0016485 226 0.030
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.030
cytokine metabolic process GO:0042107 38 0.030
regulation of nucleotide catabolic process GO:0030811 205 0.030
regulation of defense response GO:0031347 154 0.030
regulation of b cell differentiation GO:0045577 2 0.030
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.029
positive regulation of programmed cell death GO:0043068 249 0.029
digestive tract development GO:0048565 75 0.029
cellular response to lipid GO:0071396 127 0.029
post embryonic organ development GO:0048569 1 0.029
leukocyte chemotaxis GO:0030595 76 0.029
purine containing compound catabolic process GO:0072523 411 0.029
oocyte differentiation GO:0009994 2 0.029
response to lipid GO:0033993 206 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
single organism cellular localization GO:1902580 332 0.029
nitrogen compound transport GO:0071705 191 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
regulation of leukocyte proliferation GO:0070663 67 0.028
positive regulation of nucleoside metabolic process GO:0045979 186 0.028
regulation of protein kinase activity GO:0045859 289 0.028
regulation of ras protein signal transduction GO:0046578 155 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
cytoplasmic transport GO:0016482 379 0.027
i kappab kinase nf kappab signaling GO:0007249 166 0.027
determination of adult lifespan GO:0008340 2 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
positive regulation of immune response GO:0050778 159 0.027
positive regulation of growth GO:0045927 58 0.027
Mouse
positive regulation of catabolic process GO:0009896 310 0.027
regulation of neuron differentiation GO:0045664 70 0.026
peptidyl tyrosine modification GO:0018212 170 0.026
pericardium development GO:0060039 2 0.026
wound healing GO:0042060 115 0.026
leukocyte migration GO:0050900 107 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
chemical homeostasis GO:0048878 306 0.026
memory GO:0007613 3 0.025
negative regulation of immune system process GO:0002683 136 0.025
reactive nitrogen species metabolic process GO:2001057 3 0.025
nucleoside catabolic process GO:0009164 408 0.025
protein maturation GO:0051604 233 0.025
sequestering of calcium ion GO:0051208 17 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
response to wounding GO:0009611 168 0.025
peptidyl lysine acetylation GO:0018394 101 0.024
reactive oxygen species biosynthetic process GO:1903409 4 0.024
guanosine containing compound catabolic process GO:1901069 239 0.024
positive regulation of organelle organization GO:0010638 195 0.024
oocyte development GO:0048599 1 0.024
stem cell division GO:0017145 2 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
golgi organization GO:0007030 38 0.023
cellular lipid metabolic process GO:0044255 303 0.023
neuron differentiation GO:0030182 138 0.023
regulation of homeostatic process GO:0032844 121 0.023
actin cytoskeleton organization GO:0030036 207 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
positive regulation of defense response GO:0031349 87 0.023
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
regulation of protein transport GO:0051223 213 0.023
tissue migration GO:0090130 119 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
negative regulation of cytokine production GO:0001818 82 0.023
inflammatory response GO:0006954 79 0.023
regulation of leukocyte mediated immunity GO:0002703 38 0.023
regulation of vesicle mediated transport GO:0060627 130 0.023
positive regulation of ras gtpase activity GO:0032320 117 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
phosphatidylinositol mediated signaling GO:0048015 55 0.022
positive regulation of map kinase activity GO:0043406 80 0.022
negative regulation of cell migration GO:0030336 102 0.022
regulation of cell cycle process GO:0010564 266 0.022
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
central nervous system development GO:0007417 123 0.022
Mouse
purine nucleotide catabolic process GO:0006195 405 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
regulation of gtp catabolic process GO:0033124 180 0.022
regulation of endothelial cell migration GO:0010594 67 0.022
embryonic epithelial tube formation GO:0001838 4 0.022
amide transport GO:0042886 76 0.021
neurogenesis GO:0022008 169 0.021
embryo development GO:0009790 123 0.021
positive regulation of kinase activity GO:0033674 204 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.021
cardiovascular system development GO:0072358 262 0.021
regulation of cell division GO:0051302 116 0.021
internal peptidyl lysine acetylation GO:0018393 97 0.021
intracellular protein transport GO:0006886 270 0.021
regulation of multi organism process GO:0043900 157 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
cell projection organization GO:0030030 252 0.021
regulation of secretion by cell GO:1903530 177 0.021
regulation of neurogenesis GO:0050767 82 0.021
chemotaxis GO:0006935 157 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.020
single organism reproductive process GO:0044702 98 0.020
actin filament based process GO:0030029 224 0.020
protein kinase b signaling GO:0043491 69 0.020
lipid metabolic process GO:0006629 381 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
regeneration GO:0031099 4 0.020
positive regulation of cell motility GO:2000147 177 0.020
positive regulation of cell development GO:0010720 92 0.020
motor neuron axon guidance GO:0008045 2 0.020
regulation of leukocyte differentiation GO:1902105 61 0.020
Mouse
negative regulation of organelle organization GO:0010639 126 0.020
regulation of proteolysis GO:0030162 293 0.020
epithelium development GO:0060429 227 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
divalent metal ion transport GO:0070838 152 0.019
regulation of kinase activity GO:0043549 314 0.019
regulation of intracellular transport GO:0032386 195 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
regulation of gtpase activity GO:0043087 180 0.019
positive regulation of response to external stimulus GO:0032103 88 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
cellular metal ion homeostasis GO:0006875 146 0.019
positive regulation of cell death GO:0010942 263 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.019
regulation of cytokine secretion GO:0050707 57 0.019
secretion by cell GO:0032940 226 0.019
negative regulation of protein modification process GO:0031400 200 0.019
somatic stem cell division GO:0048103 1 0.019
cell morphogenesis GO:0000902 296 0.019
positive regulation of cytokine production GO:0001819 167 0.019
histone h4 acetylation GO:0043967 47 0.019
epithelium migration GO:0090132 119 0.019
endocytosis GO:0006897 159 0.019
muscle structure development GO:0061061 98 0.019
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.018
negative regulation of cell motility GO:2000146 104 0.018
histone deacetylation GO:0016575 32 0.018
regulation of peptide transport GO:0090087 62 0.018
negative regulation of cell cycle GO:0045786 193 0.018
tissue regeneration GO:0042246 3 0.018
regulation of lymphocyte proliferation GO:0050670 64 0.018
leukocyte mediated immunity GO:0002443 59 0.018
segmentation GO:0035282 4 0.018
apoptotic signaling pathway GO:0097190 268 0.018
regulation of jak stat cascade GO:0046425 44 0.018
neuroblast proliferation GO:0007405 4 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
cell projection morphogenesis GO:0048858 129 0.018
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.018
phospholipid metabolic process GO:0006644 99 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
response to transforming growth factor beta GO:0071559 94 0.017
negative regulation of transport GO:0051051 176 0.017
blood vessel morphogenesis GO:0048514 162 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.017
regulation of cell cell adhesion GO:0022407 57 0.017
nervous system development GO:0007399 293 0.017
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
negative regulation of developmental process GO:0051093 247 0.017
metal ion transport GO:0030001 272 0.017
regulation of peptidase activity GO:0052547 180 0.017
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.017
behavioral response to ethanol GO:0048149 2 0.017
guanosine containing compound metabolic process GO:1901068 244 0.016
cation homeostasis GO:0055080 189 0.016
positive regulation of nervous system development GO:0051962 54 0.016
developmental process involved in reproduction GO:0003006 66 0.016
response to fungus GO:0009620 4 0.016
regulation of binding GO:0051098 111 0.016
jak stat cascade GO:0007259 46 0.016
cellular response to organonitrogen compound GO:0071417 124 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
organelle assembly GO:0070925 176 0.016
negative regulation of proteolysis GO:0045861 132 0.016
humoral immune response GO:0006959 49 0.016
protein localization to organelle GO:0033365 280 0.016
positive regulation of lymphocyte activation GO:0051251 73 0.016
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.016
anatomical structure homeostasis GO:0060249 100 0.016
peripheral nervous system development GO:0007422 2 0.016
regulation of dna metabolic process GO:0051052 153 0.016
pattern specification process GO:0007389 43 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
nuclear transport GO:0051169 179 0.016
positive regulation of gliogenesis GO:0014015 4 0.016
endothelial cell migration GO:0043542 86 0.016
intracellular receptor signaling pathway GO:0030522 104 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
regulation of vasculature development GO:1901342 97 0.016
regulation of protein processing GO:0070613 150 0.016
blastoderm segmentation GO:0007350 2 0.016
ossification GO:0001503 121 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
regulation of chemokine production GO:0032642 31 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
long term memory GO:0007616 2 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
t cell selection GO:0045058 4 0.015
positive regulation of secretion by cell GO:1903532 108 0.015
erk1 and erk2 cascade GO:0070371 104 0.015
response to lipopolysaccharide GO:0032496 70 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
secretion GO:0046903 254 0.015
negative regulation of growth GO:0045926 97 0.015
microtubule based process GO:0007017 210 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
regulation of cellular response to stress GO:0080135 244 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
internal protein amino acid acetylation GO:0006475 101 0.015
myeloid cell differentiation GO:0030099 117 0.015
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.015
stress activated protein kinase signaling cascade GO:0031098 94 0.015
regulation of angiogenesis GO:0045765 92 0.015
compound eye development GO:0048749 1 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
positive regulation of leukocyte activation GO:0002696 80 0.015
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
positive regulation of mononuclear cell proliferation GO:0032946 47 0.015
regulation of innate immune response GO:0045088 97 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
sequestering of metal ion GO:0051238 24 0.015
neural tube formation GO:0001841 3 0.015
regulation of immunoglobulin production GO:0002637 4 0.014
tube morphogenesis GO:0035239 95 0.014
negative regulation of locomotion GO:0040013 118 0.014
regulation of nervous system development GO:0051960 88 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
regulation of secretion GO:0051046 194 0.014
response to radiation GO:0009314 151 0.014
cellular cation homeostasis GO:0030003 163 0.014
regulation of epithelial cell proliferation GO:0050678 113 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
positive regulation of cell adhesion GO:0045785 84 0.014
cytokine secretion GO:0050663 64 0.014
single organism membrane organization GO:0044802 268 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
salivary gland morphogenesis GO:0007435 4 0.014
negative regulation of immune response GO:0050777 40 0.014
pattern recognition receptor signaling pathway GO:0002221 48 0.014
regulation of b cell proliferation GO:0030888 18 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
antigen receptor mediated signaling pathway GO:0050851 38 0.014
regulation of chromatin organization GO:1902275 56 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
regulation of actin filament based process GO:0032970 141 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
protein acetylation GO:0006473 116 0.014
positive regulation of transferase activity GO:0051347 227 0.014
cation transport GO:0006812 331 0.014
regulation of transcription by chromatin organization GO:0034401 1 0.014
pyrimidine containing compound transmembrane transport GO:0072531 4 0.014
cellular response to lipopolysaccharide GO:0071222 57 0.014
histone acetylation GO:0016573 93 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
regulation of erk1 and erk2 cascade GO:0070372 99 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
regulation of growth GO:0040008 165 0.013
Mouse
regulation of endocytosis GO:0030100 72 0.013
innate immune response activating signal transduction GO:0002758 48 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
inner ear morphogenesis GO:0042472 4 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.013
myeloid leukocyte activation GO:0002274 34 0.013
membrane organization GO:0061024 292 0.013
positive regulation of leukocyte proliferation GO:0070665 48 0.013
cell growth GO:0016049 160 0.013
adaptive immune response GO:0002250 49 0.013
positive regulation of interferon gamma production GO:0032729 26 0.013
protein targeting to nucleus GO:0044744 104 0.013
protein secretion GO:0009306 98 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.013
spermatid differentiation GO:0048515 4 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.013
regulation of b cell activation GO:0050864 24 0.013
Mouse
regulation of protein secretion GO:0050708 86 0.013
stem cell differentiation GO:0048863 93 0.013
b cell activation GO:0042113 33 0.013
Zebrafish Mouse
dna recombination GO:0006310 77 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
cellular extravasation GO:0045123 21 0.013
mitotic cell cycle GO:0000278 326 0.013
protein targeting GO:0006605 187 0.013
activation of innate immune response GO:0002218 55 0.013
vitamin transmembrane transport GO:0035461 4 0.013
response to bacterium GO:0009617 144 0.013
platelet activation GO:0030168 44 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
regulation of ion homeostasis GO:2000021 73 0.012
regulation of smooth muscle cell differentiation GO:0051150 3 0.012
response to nitrogen compound GO:1901698 184 0.012
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.012
mitotic cell cycle process GO:1903047 286 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
nerve development GO:0021675 4 0.012
endosomal transport GO:0016197 129 0.012
positive regulation of protein transport GO:0051222 135 0.012
regulation of glial cell differentiation GO:0045685 3 0.012
positive regulation of immunoglobulin production GO:0002639 4 0.012
regulation of protein maturation GO:1903317 150 0.012
thiamine transport GO:0015888 3 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
glycoprotein metabolic process GO:0009100 110 0.012
regulation of neuroblast proliferation GO:1902692 3 0.012
chemokine production GO:0032602 32 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
regulation of hormone levels GO:0010817 125 0.012
cellular protein complex assembly GO:0043623 188 0.012
negative regulation of protein maturation GO:1903318 142 0.012
response to alcohol GO:0097305 64 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012

IKZF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.044
sensory system disease DOID:0050155 203 0.023
eye and adnexa disease DOID:1492 150 0.023
nervous system disease DOID:863 431 0.023
eye disease DOID:5614 149 0.023
musculoskeletal system disease DOID:17 223 0.016
disease of cellular proliferation DOID:14566 174 0.015
central nervous system disease DOID:331 186 0.014
hematopoietic system disease DOID:74 100 0.012
primary immunodeficiency disease DOID:612 36 0.012